Monocytes igazi anda: njengoba kufakazelwa ukuhlaziywa

Sonke ngezikhathi senzakalo ngezokwelapha usithe. Njengoba CBC ukudlula konke, kukhona njalo nawu umbuzo, uyini monocytes, bangaki kubo kumele kube usegazini, futhi njengoba kufakazelwa ukubaluleka etholakale lapho igazi monocytes bayanda?

Monocytes - makhulu ngobukhulu kwamangqamuzana egazi abomvu, okuqondene ekilasini amangqamuzana amhlophe egazi. Ngokusho isakhiwo - amaseli okusaqanda ne-nucleus ezinkulu kanye nokuntuleka zokusanhlamvu cytoplasm (agranulocytes) Sabela ngokushesha izinqubo ukuvuvukala kule ukwanda umzimba egazini labo. Isimo lapho monocytes igazi ephakeme, ngokuthi monocytosis.

La mangqamuzana akhiwa umnkantsha ka monoblastov ngenkathi they ezihlukaniswe meiosis, futhi ngemva kwezinsuku ezimbalwa uthuthe kusukela egazini ezicutshini, futhi kukhona emangqamuzaneni ehilelekile phagocytosis. Ezimweni eziningi, le nqubo siyenzeka ekuphenduleni Ukungena ukutheleleka lapho monocytes babe macrophage kakade axhunyiwe ukusekela amasosha omzimba futhi ivimbela amaprotheni angaphandle ukwakha inhlanganisela antigen-omzimba. Ngo inqubo phagocytosis ka monocytes kungukuthi liqothulwe, njengalokho ngokuvamile kwenzeka eosinophils futhi neutrophil, kodwa yakha umgodi belinganisa isayithi ukuvuvukala. Sici sici iyafana ukuziphatha kwalezi amaseli ezindaweni ene-asidi.

Monocyte iqukethe inqwaba lysosomes, okuyinto inhlabamkhosi iseli fagotsitiruemye izinto nokususa lesion indawo futhi silungiselela wona ukuvuselelwa. Ingabe ngokuyinhloko monocytes egazini, kukhona ngobuningi ekhona ubende, izindlala zamanzi kanye umnkantsha, ngakho ukulimala komunye wabo uzokwehla monocytes. Monocytosis liphinyiselwe izimila ebulalayo, izifo ezithathelwanayo (ugcunsula, isifo sofuba), izifo letindzala (lupus erythematosus, izifo wegazi), collagenosis, granulomatosis.

Okuqukethwe lezi leukocyte mononuclear ku evamile neuropathy igazi - hhayi ngaphezulu kuka-0.03 - 1.00 × 109 / L, futhi lemali yabo Imininingwane kumele singeqi 8-10% we-leukocyte Imininingwane. Uma monocytes ngenhla kuyinsakavukela, kuba yithuba iphumelele ekuhlolweni ezengeziwe zokubona umthombo ukutheleleka kanye imithi yokwelashwa engafanele. Monocytes nethonya cytotoxic (nethonya elilimazayo isimila cells kanye izifo ezifana umalaleveva), ukukhiqiza eselaphayo (IFN), zinengxenye ukuqashelwa amanxusa akwamanye amazwe.

Ngisho noma monocytes igazi bayanda, akunakwenzeka ukuba kahle ukuchaza isithombe izibikezelo ukuvuvukala, okusekelwe kuphela izinkomba zabo ambalwa. Ngenxa yale njongo silinganisela inani leukocyte formula igazi: uma eziningi monocytes, begodu kukhula isibalo lymphocyte futhi, kanti ingxenye efanayo eosinophils, kodwa inombolo ukuncipha T-lymphocyte okuqukethwe, kungase kubhekwe njengokwelapha isizathu umphumela omuhle ka isimo sokugembula. Ngokungafani nesimo lapho monocytes igazi matasa ngokwengeziwe ngokomoya njengoba isibalo neutrophil leukocyte shift kwesokunxele, kanyekanye ukwehla inani eosinophils ne-T-lymphocyte.

Uma nokwehla elibukhali inani monocytes siyenzeka egazini, bese kuziwa esimweni ezifana monocytopenia (monotsitopeniya). Lesi sithombe siyenzeka egazini umnkantsha izilonda, lapho gemapoeza inqubo i- e generalized ubovu izifo, izifo igazi, imithi hormone, ukucindezeleka futhi ukushaqeka izimo, sokubeletha izinqubo zokuhlinza, kanye ukulimala emizimbeni lapho monocytes zisekelwe. Esimeni inani monocytes egazini neuropathy kubalulekile ukuqhuba ukuhlolwa igazi yesibili. Kulesi sisekelo, kuyothiwa babelwe ukuphathwa okuhambisanayo eziyinkimbinkimbi lesi sifo ecashile. Njengoba monocytes aphendule khona ukutheleleka emzimbeni, kungashiwo kushiwo ngokuqiniseka ukuthi main kuzogxilwa yokwelapha ngemithi elwa namagciwane plus ukwelashwa lingaze.