Treponema pallidum (Treponema pallidum) - i-ejenti causative of ugcunsula

Treponema pallidum - igciwane kuyingozi kakhulu, i-ejenti causative of ugcunsula. It ngokushesha lingena singene nomzimba womuntu futhi ngezinga elifanayo Ukhuthaza, ngaleyo ndlela eziphatha kakhulu kwezitho zangaphakathi.

incazelo amagciwane

Treponema pallidum - bacterium kokuba ulwelwesi cell. Ukwazi ukuphila isikhathi esithile e imvelo. Lokhu igciwane kungokwalabo spirochaetes. Kubonakala sengathi i-curls Kuvunguza encane, okungaba kusukela izingcezu eziyisishiyagalombili kuya kweziyishumi nambili. Vele ngobuningi balokho okunikelwayo yabo futhi uhlobo igciwane kutholwa lapho microscopy smear kwenziwa.

Lokhu silwanyana neze ezinemibala udayi, ezisetshenziswa i-microbiology. Ukuze ubone igciwane esetshenziswa Ngokuphambene microscopy. Lokhu kungenxa yokuthi igobolondo mncane kakhulu micro-umzimba ngaphansi kwethonya utshwala ezilimele ngokushesha (futhi nje asetshenziselwa umbala nenkanuko edlulele). Lapho ama-bacterium esiliva-kuhlinzwa kuba nombala onsundu-black.

isikhathi esingakanani ama-bacterium bukhoma

Treponema pallidum nabo izinto (ikakhulukazi utshani kanye amathawula) inakekelwa kuze substrate ezomile, lapho kwaba. Ngokuvamile kuba ngamathe ezikhishwe uketshezi izilonda futhi erosions, isidoda kanye nokunye. D. At lokushisa amahlanu nanhlanu degrees igciwane angaphila cishe imizuzu engu-nanhlanu. Ngezinye die ephakeme ngokushesha. Phakathi abilayo amabhaktheriya afele indaba ngemizuzwana, okungukuthi, ngokuphazima kweso.

Yikuphi okungukuthi umonakala amagciwane

Ukuze Treponema pallidum ezinye imvelo eziyingozi kanye izinto:

• bismuth futhi arsenic;
• mercury;
• penicillin akuzange kusize,
• alikhali futhi acid;
• antiseptics futhi izibulali-magciwane;
• uviniga utshwala;
• Ufo nokukhanya.

Ngokocwaningo olwenziwa futhi ucwaningo olwenziwe ososayensi, kwatholakala ukuthi lolu igciwane kungaba ziqhubeke isikhathi eside isikhathi esithile futhi nangaphansi kwezimo ezingezinhle ngenxa yalo. Ngokwesibonelo, endaweni embi, ngaphansi ekukhanyeni, isimo omisiwe noma khona komoya-mpilo. Uma uhlangabezana ikhophi silwanyana, ke bangaphila endaweni enobutha ngaye iminyaka emithathu.

Treponema ukukhula antigen ezinkulu

Treponema pallidum kahle kutshalwa ngenxa capriciousness yayo. Amaseli we iphuphu zemibungu womuntu ayifanele ukutshala lolu umzimba. Kunezindlela ezimbili, indlela isiko kungathiwa. Eyokuqala - amabhaktheriya ngegciwane onogwaja laboratory, bese ulinda ukuthuthukiswa kwalezi zilwane orchitis ethize. Okwesibili - treponemu zingatshalwa kwimidiya ekhethekile ngaphansi uwoyela amaminerali. Ukuba khona kwalawa eziphilayo kuyadingeka ukuze uthole antigen ngawo ugcunsula kunqunywa.

Pathogenicity Treponema pallidum

Pathogenic amagciwane treponema pallidum has izici zayo siqu:

• sibonga amaprotheni adhesin ukuthi kuwuthinta fibronectin mucosal enikeziwe 'osekela ngcono "ukusingatha amaseli;
• khona myofibrils nomumo Kuvunguza Treponema pallidum ukukhuthaza Ukungena ezijulile futhi abangele yokufuduka umzimba;
• antifagotsitarnaya umsebenzi kungenxa ikhono amabhaktheriya ukuba ngibophe abanhliziyo fibronectin;
• kuba abavusa ngenxa yokubakhona Esilula ulwelwesi;
• treponema pallidum amelana ejenti elwa namagciwane ngenxa kokuhlukana izakhiwo antigenic futhi ikhono kumiswa L-amafomu, okwenza kube akukwazeki ukudala wokugoma;
• Lezi amabhaktheriya akuzona kuphela okwazi ukuphila le interstices, kodwa futhi anandise khona.

Amasosha Omzimba ukuze Treponema pallidum

Treponema pallidum ikakhulukazi eqoqwe nolwelwesi lwamafinyila. Ngakho-ke ngobulili nje kuphela ngokusebenzisa ubuhlobo bobulili, kodwa futhi ekuphileni kwansuku zonke kalula. Iningi ngokuvamile ngokusebenzisa amathawula, izinto noma Kissing. Ngeshwa, umzimba womuntu awukwazi ukuthuthukisa amasosha omzimba ukuba la magciwane. Ngakho-ke, ngisho nangemva ikhambi eliphelele yesifo ugcunsula ungabuyela.

Ukuze ubone ukuthi lesi sifo igazi uyiswa ugcunsula. Iningi itheleleke babe amasosha Treponema pallidum. Ngo isifo eyinhloko futhi yansukuzonke - e 88 kanye 78% ngokulandelana. Konke okunye ngabe yini avelayo noma lumane. Kodwa ukungabi omzimba akufakazeli ukuthi uphathwa yimpumelelo. On esigabeni esicashile zesifo i omzimba ikakhulukazi wathola amaphesenti 20 kuphela eziguli.

Ngemva kwamasonto 1-2 kusukela ekuqaleni lesi sifo ukuhlaziya serum. Igm futhi Iga amasosha treponema pallidum e serum avele ngalesi sikhathi. Phakathi nenkathi ngemva kwezinyanga eziyisithupha kuya eziyisishiyagalolunye izinyanga titers ka immunoglobulin ekuphumeni ke iqala ukwehla hlangana nenani labo. Ngokusebenzisa isikhathi lize liba ngaphansi kwe value enqunyiwe nangokwazi ezingeni kwamasosha omzimba. Ezinye ayikwazi ngocansi kusuka kumama kuya enganeni.

IgG amasosha omzimba ukuvela ngemuva 3-4 amasonto ukutheleleka nge ugcunsula. A 6-9 ngesonto ukufinyelela Selilonke. A lokuhlushwa enkulu omzimba inakekelwa isikhathi eside, futhi kunciphe kancane kakhulu futhi kuphela emva kokwelashwa. A titers asalile kungase kuphikelele emzimbeni impilo.

Treponemal amasosha omzimba zingaba kuphela Treponema pallidum. Ngakho-ke, lapho khona kwabo ongacela ngokunembile ukuthi ugcunsula kuyinto okwamanje noma ihanjiswe ngaphambili.

Izimpawu ze-isifo Treponema pallidum

Kunezindlela eziningana izimpawu eveza khona emzimbeni womuntu Treponema pallidum. Lapho zivela kudingekile ukuba unikele ngegazi ukuze ugcunsula. Izimpawu kungehluka kuye ngokuthi isiphi isigaba sayo lesi sifo.

Esikhathini sokuqala:

• ngamathumba amabi kuvele chancre, ise umlomo, ingemuva noma Izitho zangasese;
• evuvukele zamanzi;
• ngokuzimela izilonda kuthiwa some okungenani amaviki amathathu, inqubo kungathatha izinyanga eziyisithupha.

On the yesibili:

• ziyalingana okhanyayo ukuqubuka syphilitic liyavela umzimba;
• ikhanda, ukucobeka umkhuhlane;
• evuvukele zamanzi;
• ngezinye izikhathi ukulahlekelwa izinwele zakhe, warts zangasese avele ebanzi.

Ngekhulu lesithathu kukhona ukunqotshwa:

• isimiso sezinzwa;
• asebuchosheni nomgogodla;
• izitho zangaphakathi;
• amathambo.

Ezigabeni lokuqala nelesibili ukwelashwa ngempumelelo oluphelele ebandakanya antibiotic, Physiotherapy, ngokubhukula futhi immunostimulants amalungiselelo. Kodwa uma isikhathi akusho ukubona udokotela, iminyaka ke ezimbalwa kamuva waqala esigabeni sesithathu lesi sifo, ukwelapha ukuthi cishe kungenakwenzeka.

Njengoba kwembulwe treponema okhanyayo?

Ukuze anqume ukuthi bukhona yini emzimbeni amagciwane ezibangela ugcunsula, kuba ukuhlaziywa ezifanele. imizamo Treponema pallidum wokuphila emkhakheni wamuva wezokwelapha kungatholakala ngezindlela eziningana:

• Ngo esigabeni sokuqala ugcunsula isiguli esithathelanayo kakhulu futhi zigqamise emhlabeni eziningi zama-bacterium. Kulokhu i-microscopy smear. Ukuze uthole imiphumela olunembile, izilonda ziphathwe Washout nosawoti ngokuphazamisana flora. Khona-ke wazenzela nokususa, wabumba smear.
• Non-treponemal ukuhlolwa. Kube wasebenzisa izindlela ukuhlolwa. Ziyakwazi kuhle uphethwe kokuqala nokulandelela ngesikhatsi ukwelashwa kanye luhlolo emtholampilo. Kodwa lolu vivinyo bavame ukunikeza imiphumela emihle zamanga. Treponema pallidum kulokhu kungase kungabi khona emzimbeni. Kungenxa yokuthi nomfutho wegazi ophezulu (amasosha omzimba ngokumelene antigen) kungukuthi kuthathwe lwegciwane.
• ukuhlolwa Treponemal asetshenziswa kuyinto ukuthola Treponema pallidum. Lezi izindlela ezisetshenziswa ukuqinisekisa ukuxilongwa kanye exclusion ugcunsula ngesikhathi okungalungile Ukuhlolwa ukuhlolwa.