"Corinfar": kuzibuyekezo, izintengo, yokusetshenziswa

"Corinfar" - umuthi bohlanga ka-calcium channel blocker. Umuthi evimbela Ukungena kwe-calcium ion e ulwelwesi cell, ngaleyo ndlela kuncishiswe ithoni izindonga imithambo yegazi, ngakho-ke livame ukusetshenziswa ngesikhathi ingcindezi ephakeme. I nomuthi has umphumela antianginal, kanjalo iphathwa ngempumelelo esingamahlalakhona senhliziyo yesifo senhliziyo. "Corinfar Uno" izilinganiso ukuboniswa njengenhlangano agent eliphumelelayo ekupholiseni angina.

ifomu ukukhululwa, izithako ekhona Ukwakheka

Umuthi itholakala amaphilisi, ifilimu-camera. isithako, njengoba nifedipine isetshenziswa ukubunjwa iphilisi elilodwa elikhona 10, 20 noma 40 mg.

izithako Asizayo kukhona magnesium stearate, amazambane isitashi, lichaza ekwakheni yethuliwe povidone K25, monohydrate lactose futhi microcrystalline cellulose.

imiphumela kwemithi

umphumela Hypotensive zomuthi ingawenza buthaka futhi wenze zisaphila ambalwa. Izinguquko ezinjalo, ngakho emzimbeni kungaholela ekuncipheni isidingo inhliziyo ukuze umoya-mpilo. Enhanced yenhliziyo ukugeleza kwegazi sebephuze izingilazi izindlela "Corinfar". Yokusetshenziswa, izimpendulo ibonisa ukuthi ukwelashwa nale izidakamizwa kuholela ushintsho oluhle ezindaweni we myocardium, lapho abaphukile kwegazi.

I nomuthi iqala ukwenza emva mayelana amabili imizuzu emva ukusetshenziswa, umphumela okuholela ihlala amahora amahlanu. Ngemva pheshana emathunjini lingene egazini lingena mayelana 90% izidakamizwa, ileveli enkulu ejenti asebenzayo kufinyelelwa kungakapheli amahora amathathu ngokwesilinganiso. Ukulungiswa has okusezingeni eliphezulu bioavailability izinkomba (50 ku-70%), okuyinto enomthelela ukwandisa ukudla, futhi ngenxa plasma amaprotheni (95%). Amafomu izidakamizwa edepho kusindisa yi at angu-24.

Kuyaziwa ukuthi sidlula zemvelo izithiyo ukulungiselela "Corinfar" ngesikhatsi ukwelashwa ezaziwayo. Izibuyekezo babike ukuthi imithi akwazi ukuwela placenta futhi gazi ebuchosheni, butholakala ukubunjwa ubisi lwebele. Umzimba "corinfar" kwenzeka esibindini. Izinqubo hydrolyzation kanye namachibi kuholela ekwakhekeni metabolites ngasebenzi, iningi okuyinto excreted ku umchamo, lonke - ngokusebenzisa emathunjini e Bile. 1% zomuthi akukwazi izinqubo umzimba, futhi sidlula izinso zinjalo. ukuqedwa kwengxenye zomuthi Kwenziwa amahora amabili kuya kwamahlanu, izinkinga esibindini - eside.

ubufakazi

Umuthi ezinqunyiwe nomfutho wegazi ophezulu, kanye okufana angina, ezinzile pectoris angina namafomu okungamahlalakhona (CHD). Ngu izinkomba zihlanganisa isifo Raynaud sika, colic (emathunjini, biliary, kwezinso), ukuvimbela bronchial, isifuba somoya bronchial (ukwelashwa eziyinkimbinkimbi).

Izimo

Imiyalelo emuthini "Corinfar" Izibuyekezo babike ukuthi ukwelashwa ngalo muthi akuvunyelwe kulezi zimo ezilandelayo:

• Hypersensitivity kuya izindlela ebalulekile;
• ukushaqeka cardiogenic;
• acute esivimba amanzi infarction umumo (kuqala amasonto 4);
• umfutho ophansi wegazi - hypotension, lapho-systolic blood pressure lehla ngezansi 90 mm HG. Article.
• lwemithambo stenosis (esibi kakhulu);
• angina (engazinzile) ;
• amafomu njalo congestive inhliziyo ukwehluleka (isinyathelo decompensation);
• senyanga yokuqala lapho okuvikela ingane breastfeeds.

Ezimweni lapho kuhlelwe lokufeza ukwelashwa izidakamizwa "Corinfar" Izibuyekezo ukuncoma ngokuqapha ekukhombeni lezi zithi:

• ukwehluleka isibindi, izinso,
• umfutho wegazi ophakeme emithanjeni kokuba uhlamvu abulalayo;
• wamathumbu isimiso;
• bradycardia, tachycardia;
• isilethikusebenza (ikakhulukazi ezimweni lapho bekubona ventricular kwesokunxele ukwehluleka) ;
• notshwala okukhulu kwegazi cerebral;
• stenosis lapho valve mitral kuthintwa;
• ubudala esingaphansi 18 noma kuka-60.

Ngesikhathi sokwelashwa kufanele uhlukane nale ubhamubhamu juice, ngoba ngemva ukusetshenziswa kwayo kuhlukumeza umzimba isithako zomuthi.

ukwelashwa

Sebenzisa "Corinfar" ukubuyekezwa, imiyalelo Kunconywa emva kokudla, hhayi liquid usebenzisa amanzi amaningi. Umthamo izidakamizwa akhethiwe kumuntu ngamunye, kuya ukuzwela yezingxenye kanye nesineke.

angina Vasospastic amafomu ezingamahlalakhona ekuqaleni babelwe izindlela ezimbili noma ezintathu ethola e umthamo owodwa we-10 mg. Phezu kokuthola umphumela enganele okwandisa umthamo nomuthi inemvume mg 20. Emini awukwazi ukuthatha ezingaphezu kuka-40 mg zomuthi.

Lapho kubalulekile nomfutho wegazi ophezulu umthamo isilinganiso izidakamizwa luyadingeka ukwamukela ngosuku oluhambisana izibhebhe ezimbili noma ezintathu 10 mg. Ngesinye isikhathi ungase aphuze iphilisi elilodwa. A umthamo owodwa kungase kukhule ku izibhebhe ezimbili. Usuku angeke baphuze amaphilisi angaphezu kuka ezine. Kuyadingeka ukuba bagcine lesine isikhawu esincane phakathi ngamunye engayitholi izidakamizwa.

10 mg Tablets

Isikali ezinconyiwe - iphilisi elilodwa engayitholi nsuku zonke, kabili kuya kulokutsatfu uma kunesidingo ukwandisa umthamo - izibhebhe ezimbili ngesikhathi imvamisa kwesicelo kanye noma kabili ngelanga. Akuvunyelwe zisebenzisa usuku ezingaphezu kuka-40 mg zomuthi.

Tablets 20 mg 40

"Izibuyekezo Corinfar kuthiye ukukhula 'futhi Umhlahlandlela Kunconywa ukuba asebenzise okungenani kabili ngosuku - amaphilisi elilodwa noma amabili kuphela ngesikhathi.

Umuthi ngesikhathi umthamo 40 mg ( "Corinfar Uno") okumele asetshenziswe kanye ngosuku, okungcono ekuseni, esinye isibhebhe sibonisa kwanele.

side effects

izenzo Esibi okungabangela izidakamizwa ne obuhlukahlukene Isikali ingxenye main zihlanganisa yokuphazamiseka esimiso senhliziyo nemithambo yegazi kanye uhlelo hemopoietic, ngomgudu womchamo, ekusebenzeni kwesibindi kanye emathunjini. Imiphumela emibi engase yenzeke isimiso sezinzwa esiyinhloko, uhlelo zemisipha. komzimba.

Uma wokugoqa kwenzeka, kukhona ubuhlungu esifubeni, umuthi ngokushesha amankeyane. Ezimweni lapho umthamo watusa weqiwe, ingaqala myalgia, paresthesia nemilenze babonakala ezimweni ezingajwayelekile isikhashana siyabhubha umbono, ukukhathala samanje. ngezinye izikhathi ukwelashwa eside kuholela ukubukeka gynecomastia kwasebekhulile, ekuthuthukiseni Hyperplasia gingival futhi Hyperglycemia. Kungatholakala nezinye izinkinga. Ngokuvamile, i-ukunyamalala side effects esanele ukwenza ukuqedwa zomuthi.

Izindleko izidakamizwa analogue

Kunconywa ukuba ubuyekeze isitatimende Imininingwane unamathele izidakamizwa "Corinfar" intengo, nozakwabo yangempela. Thenga imithi (amaphilisi 50) kungabangwa ruble 70-85 ngokwesilinganiso.

Phakathi kwezidakamizwa analogue - "Nikardiya", "fenigidin", "Nifadyev". Ngenxa esikhundleni ingasetshenziswa "Nifelat", "Kaltsigard", "Farmadipin" noma "Nifedikap". Mhlawumbe ukwelashwa nge "Nifecard", "cordipin", "Adalat", "Nifebene", "Nifedipine". I analogs kwesakhiwo eyakhe "Kordafen", "Kordafleks". "Nifedikor" futhi "Nifegeksal" efanelekayo ukuqaliswa yokwelapha.

Izibuyekezo

Uma uhlela ukuqala ukwelashwa "Corinfar" imiyalelo ukulungiselela, intengo, ukubuyekezwa, analogue ivumela ukukhetha imithi efanele kakhulu. Izibuyekezo ukukhombisa ukuthi izidakamizwa inikeza ukunciphisa okusheshayo wegazi (isigamu sehora). Umphumela ubonakala ngisho emva eyamukelayo olulodwa kusho. Ukuze snizalos ingcindezi kumanani evamile, udokotela kufanele bakhethe umthamo ofanele kakhulu. Ngokuvamile, okwandisa umthamo isebenze uma siletha imiphumela efiselekayo akuyona etholwe, azikho ukulinganiselwa kanye nemiphumela engemihle. Abathengi ngifuna ngemali ephansi bese ukuphumelela ukwelashwa izidakamizwa. Mayelana side effects e ukubuyekeza, akukhulunywa ngaye.