Nomuthi "metipred" libhekisela isigaba izimali nomsebenzi glucocorticosteroid. Ingqikithi asebenzayo izenzo methylprednisolone. Ukulungiswa ine immunosuppressive, isenzo antiinflammatory, antiallergic umphumela sibonisa. Kusho "metipred" (imibono kusukela ochwepheshe ukhombe ke) kunciphisa isivuno lysosomal enzyme by ezibangela ukuzinza emkhayeni ulwelwesi zokugcina. Synthesis hyaluronidase nomuthi siyehla, kuvimbela ukwakheka exudate ukuvuvukala, ekunciphiseni capillary permeability, sithuthukisa microcirculation. Umuthi unomthelela ophawulekayo endleleni izinqubo umzimba. Ikakhulukazi, kwandisa ezicutshini amaprotheni ukuwohloka futhi zamagama, Hyperglycemia ithuthukisa futhi kukhona ukuhanjiswa inyuka fat muscle isibindi glycogen amazinga, ekuvimbeleni ezilamatshe aligugu e bone izicubu. Lapho ezithathwe ngomlomo, bekulokhu ukumuncwa ngokushesha futhi cishe ngokuphelele. Umuthi uyakwazi ukuwela placenta futhi gazi ebuchosheni ukuze ukungena ubisi. Excretion imikhiqizo kwamazinyo wenziwa umchamo.
"Metipred" imithi. isicelo
Umuthi Kunconywa esingamahlalakhona adrenocortical uhlobo lesibili noma eyinhloko, isifo Addison sika, thyroiditis nonsuppurative, uyisithulu Hyperplasia adrenal ngokwemvelo, hypercalcemia ngenxa izinqubo anomdlavuza. Ngu ubufakazi isimo zihlanganisa ezishile, anaphylactic, cardiogenic, ukushaqeka esibuhlungu, ukuhlukumezeka okukhulu, amanani azo ayanda ebuchosheni. Izidakamizwa "metipred" (ukubuyekezwa odokotela uqinisekise lolu lwazi) Kunconywa njengoba ithuluzi ezengeziwe exacerbation noma Yiqiniso okukhulu pathologies rheumatism. Ikakhulu, i-izidakamizwa kuboniswa ngenxa samathambo arthritis psoriatic, ankylosing spondylitis, bursitis (subacute noma sibi), tenosynovitis (acute nonspecific), i-osteoarthritis ukucindezeleka kwangemva kwenhlekelele, epicondylitis. Ngu izinkomba zihlanganisa lupus letindzala, izifo zesikhumba, ukugula serum, rhinitis (yesizini, noma zisetshenziswa), dermatitis herpetiformis uhlobo bullous. Izidakamizwa "metipred" (Odokotela futhi libuyekeza leli phuzu) siyasebenza ngoba pathologies ocular, neuritis we-optic nerve pathologies e umgudu wokuphefumula, isifo sofuba yamaphaphu, isifiso nenyumoniya. Ngu izinkomba futhi zihlanganisa izilonda e isimiso sokugaya ukudla bungene. Ikakhulu, i-nomuthi kuboniswa isifo Crohn, izilonda emathunjini, isifo sokusha kwesibindi, enteritis wendawo. izindlela letibekiwe "metipred" uma uhlela noma ngesikhathi sokukhulelwa. Kulokhu, umthamo imithi kufanele akhethwe kahle onguchwepheshe. It Kunconywa izindlela yezifo ezithile zesimiso sezinzwa. Ekunike umuthi multiple sclerosis, myasthenia gravis, ukucanuzela kwenhliziyo noma ukuhlanza ngesisekelo kokuthola cytostatics.
Izimo
izidakamizwa ezinconyiwe "metipred" (ukubuyekezwa odokotela ukuxwayisa ngale) e viral, pathologies webhaktheriya, Yiqiniso oyingozi noma ezingamahlalakhona ngamakhemikhali ngaphandle ukuvikelwa. Izimo zihlanganisa AIDS, hypersensitivity, anastomosis emathunjini, umfutho wegazi ophakeme, congestive inhliziyo ukwehluleka ezifana, kolwelwesi, iziyaluyalu umsebenzi wesibindi, poliomyelitis. Hhayi prescribers preterm izinsana, lactating iziguli.