Ejenti Antihypertensive 'Enap'. Yokusetshenziswa zomuthi

"Enap" libhekisela ukulungiswa kuhlanganiswe. It has isenzo asebenzayo hypotensive futhi isisu itholakala amaphilisi, omhlophe (amayunithi 10 emaphaketheni nentaba).

Enap. izinkomba

Phakathi ejenti antihypertensive, kabanzi namuhla zokwelapha, ke usesikhundleni esikhethekile endaweni izidakamizwa "Enap". Iziyalezo amagama ukusetshenziswa izinkomba ezimbalwa inhloso yazo:

- nomfutho wegazi ophezulu;

- kwesokunxele ventricular ukungasebenzi;

- ukumelwa inhliziyo.

Qaphela ukuthi enap kuthathwa njengesibikezelo prodrug, umsebenzi wayo kuboniswa ngemva kokufaka umzimba, lapho izingxenye izidakamizwa by hydrolysis ukwakha enalaprilat, nakho kuvimbela ACE.

Ukuze izinto asebenzayo ekulungisweni "Enap", ngaphezu enalapril, hydrochlorothiazide fanele, okuqondene iqembu isisu thiazide. Mshini isenzo ahlangene izidakamizwa kubangelwa ivolumu encishisiwe kanye sodium ketshezi imithambo yegazi, okuholela ukwehla okukhipha inhliziyo nomfutho wegazi.

Iziguli isilethikusebenza njengoba izidakamizwa "Enap" inikezwa. Yokusetshenziswa ubonisa ukuthi yokwamukela a nomuthi ezimweni ezinjalo kunganciphisa ezindaweni ezithintekile of necrosis futhi sithuthukise umzimba imisipha yenhliziyo.

Enap nethonya elihle kwezinso ukugeleza kwegazi, umuthi akusho neqhaza ekwandeni potassium excreted, okuyinto ebalulekile umfutho wegazi ophakeme emithanjeni. Lokhu kuvimbela ukuthuthukiswa izinga izidakamizwa in iziguli esingamahlalakhona kwezinso.

Iziguli isifo senhliziyo kuthuthukisa impilo ekwelapheni kusho "Enap". Yokusetshenziswa ukhuthaza izidakamizwa ngenxa ukuncishiswa ngokwempilo yangenyama laligujwa in iziguli congestive yokumelwa yinhliziyo. Ukuphumelela kusho ukungakwamukeli encishisiwe kuye ezingeni renin e oketshezini olungenambala lwegazi, ubudala lesiguli, ubulili bakhe. kungekho izincazelo amacala ukonakaliswa izidakamizwa "Enap" umsebenzi zocansi zokwelapha. Ukufundiswa futhi kukhomba ukungabi khona umphumela ongemuhle zomuthi ku lipid kanye carbohydrate umzimba emzimbeni.

"Enap" izidakamizwa. izakhiwo pharmacokinetic

Absorption ye-ejenti asebenzayo kwenzeka ogxile ngokusebenzisa ipheshana wokugaya ukudla (cishe 60%), inqubo ukuncela akuxhomekile isikhathi ngemva kwesidlo. Kakade emva 1 ihora kukhona ekuqaleni "Enap" zomuthi. Umhlahlandlela kubonisa umphumela evelele zokwelapha zomuthi, okuyinto eyenzeka emva esiphezulu 6 amahora ngemva kokuphathwa, esebenzayo izidakamizwa umphumela iqhubeka izinsuku.

Izimo futhi side effects

Izimo ukusetshenziswa kwezidakamizwa "Enap" imiyalelo ukusebenzisa:

- anda nozwela isiguli izingxenye zalo;

- porphyria;

- angioedema ;

- nokukhulelwa;

- lactation.

Kunezindlela eziningana amathuba okuba nemiphumela engemihle ezenzeka kwezinye izimo ukuthatha izidakamizwa, "Enap". Umhlahlandlela lixwayisa ukuphathwa ngesikhathi esisodwa iziguli nezinye isisu engaholela kahle umsebenzi kwezinso. izinso iyaqala ukusebenza ukususa izidakamizwa.

Ezimweni ezingavamile, kukhona i hypotension lwemithambo (uhlamvu short-term), iziguli esekhala ikhanda njalo. Kwezinye iziguli ukuthatha izidakamizwa kuphakamisa ukuhlanza nesicanucanu, imisipha amajaqamba futhi ukuqubuka.

Izidakamizwa "Enap". ukweqisa izidakamizwa

Izimpawu main kubangelwa ukweqisa izidakamizwa isidakamizwa "Enap", yokusetshenziswa libhekisela ezimpawini hypotension. Lapho okubonakalisa nesineke kufanele abulawe, isicelo lavage esiswini futhi unike namalahle isebenze. Khona-ke kufanele kuthathwe izinyathelo ukubuyisela ivolumu wegazi afundwa kakhulu emzimbeni. Ngenxa yale njongo, isiguli iqondiswa (ngemithambo yegazi) isixazululo sodium chloride, ngakho-ke kuyadingeka ukuba balawule konke ohlelweni esibalulekile.

Ukuze ugweme ukusebenza kanzima elihlobene ne ukweqisa izidakamizwa noma imiphumela engemihle, "Enap" ukulungiselela kuyadingeka ngaphambi kokuthatha bonana nodokotela wakho.