Amavithamini Found ukuthi ukwandisa ubude bempilo

Nakuba ememezela yokusesha waphumelela njengendawo elixir wokungafi kancane ngaphambi kwesikhathi, kodwa impumelelo esiphawulekayo ngomzamo yokuqeda ukufa nokushwabana ifinyelelwe. Ngokocwaningo entsha eyanyatheliswa kumagazini i-Science, Vitamin unelungelo nicotinamide riboside (NR) ilahlekelwe ikhono zishukumisa ukuvuselelwa kwemisipha izicubu in amagundane asebekhulile, kube kwandziswa yempilo yabo.

Ukukhuluma ngale ukufohla sobala, umholi wocwaningo uJohan Averks wachaza ukuthi imithi okuzivuselela ungathola izinzuzo ezinkulu kule nguqulo. Uthi ngelinye ilanga ngosizo Izithako zokudla, singenza ngaphandle ukuhlinzwa.

Ikhono sikhiqize

Njengazo zonke ezinye izilwane, ngokuhamba kwesikhathi ekuphileni komuntu kancane kancane ilahlekelwa amaseli ngenxa yokuguga. Le nqubo yaziwa nangokuthi yokufa kwamangqamuzana engokwemvelo. Kodwa esikhundleni avele afe, umzimba wethu kuvuselela supply yayo, ekhuthaza ukuthuthukiswa stem cells.

Nokho, ngenxa yokungapheleli kwethu emhlabeni ukuthi ngokuhamba kwesikhathi, leli khono yokuvuselela kubambezela, futhi ekugcineni kuholela ekufeni komzimba. Ososayensi anentshisekelo ukunweba ukuphila komuntu. Ngakho-ke, njalo ngifuna izindlela ngokushesha uqale futhi isenzo sokuthola ngokushesha lapho kuqala sokuhudula izinyawo lesi. manje Iqembu lomhlaba wonke abacwaningi kungacacisa ukuthi okungenani eyodwa isiqeshana puzzle.

Iyini imfihlo ye-mitochondria?

Ngokwe iqembu lososayensi, ukhiye kufihlwe mitochondria zethu, okuyinto avamise ukubizwa ngokuthi "izitshalo amandla" ezitokisini zethu. Lezi organelles ezincane ukukhiqiza amandla awadingayo ukuze anhlobonhlobo izinqubo yeselula. Ukuthuthukiswa ezikhethekile stem cells, isibonelo, kuncike amandla ekhiqizwa kuleli mitochondria.

Kuye kwatholakala ukuthi ukungasebenzi mitochondrial ingenye izimpawu zokuguga. Ngakho-ke, abalobi cwaningo sinqume ukubuka ukuxhumana okuqondile phakathi lokhu ukungasebenzi kanye cell ikhono sikhiqize, benethemba lokuthola indlela ayibuyisele.

Lapho ama-stem cell ukuthuthukisa, basebenzisa amasheya osesikhundleni kwakwakhe nicotinamide adenine ihambisane dinucleotide (nad +). Kufeza indima ebalulekile ekuqinisekiseni ukusebenza evamile mitochondria. Ngakho abacwaningi wanquma ukwethula amagundane ubudala NR, okuyinto kuyisandulela nad +, ukuze sibone ukuthi yini umphumela ke kuyodingeka ekhonweni labo yokuvuselela imisipha amaseli.

imiphumela yocwaningo

Imiphumela yabonisa ukuthi ngemva nokuphathwa NR, amagundane bakwazi ukukhiqiza inombolo enkulu imisipha stem cells ukuthi kamuva eyaba imisipha besebenzisa amangqamuzana asekhulile, okwandisa ukukhuthazela umsebenzi wabo. Ngokwesibonelo, ezase bakwazi ukusebenza isikhathi eside futhi babe esimeme ngaphezulu.

Amagundane ziphathwe NR, nawo ayehlala isikhathi eside kunaleso labo abangazange inikezwe Vitamin, sifana _3. Kuyaphawuleka ukuthi balolu cwaningo akazange ayembule iyiphi enqabayo side effects ngisho nalapho iqondiswa at ebulilini NR.

Yiqiniso, umsebenzi owengeziwe kuyadingeka ngaphambi baphikisa ngokuthi ososayensi baye bakwazi ukuthuthukisa ikhambi. Phela, it is ayikaziwa kanjani ngempumelelo noma iphephile, saleli vithamini ingasetshenziswa for ekwelapheni ukuguga kubantu.