Ukwelapha olusha luzohlinzeka Ukuvikelwa impilo engezwani ezinzima?

Ososayensi base-University of Queensland e-Australia bathole indlela "Ukuvula" futhi "off" ukuzivikela komzimba kwabanye komzimba okukhulu njengesifuba somoya.

Lolu cwaningo, eyanyatheliswa kuyi JCI Insight, kusikisela ukuthi abantu endleleni umzimba osabela ngayo ukuba nomzimba ezivamile, ezifana amantongomane ne-shellfish, asisakwazi wesabe azidle. Abacwaningi bathi indlela yabo kuzosiza ukugwema izimpawu okukhulu.

Izici Ezihilelekile Kule nqubo entsha

Le nqubo entsha esekelwe Ukusula memory ukubulawa amasosha omzimba eyaziwa ngokuthi ama-T cell. Kungenxa yokuthi lokhu yokungezwani komzimba inkumbulo emithini yomugqa. Nokho, ngosizo ukwelapha ngezakhi zofuzo ithimba wakwazi ukunciphisa ukuzwela kwesimiso somzimba sokuzivikela ezifweni futhi linikeza isivikelo sangempela.

"Izimpawu ezenzeka umuntu abanomzimba ongezwani nezinto ezithile noma isifuba somoya, ziwumphumela ukusabela amaseli abazazi allergen amaprotheni, - kusho uProfesa Ray Steptoe, owayehola kulolu cwaningo -. Emsebenzini wabo abacwaningi esetshenziswa allergen yokwenza icuphe somoya, kodwa indlela entsha kungaba esetshenziselwa abantu abanemizimba engezwani ezinzima ukuze amantongomane, bee Isihlungu, izimbaza, kanye nezinye izinto. "

Ekutadisheni kwabo, abacwaningi baye bathola ama-stem cell yegazi ungeze isakhi ulawula allergen amaprotheni. Bathola ukuthi inkumbulo yokungezwani komzimba maqondana ukuzivikela komzimba kungaba zisuswe. Ngakho, nge ukuchayeka ngokuphindaphindiwe kuze allergen kuba nokwenzeka ayeke ukusabela komzimba kuso. Lokhu kusho ukuthi, esikhundleni kokuma izimpawu, ososayensi sizokwazi ukunqanda lesi sifo uqobo, ngisho nangaphambi sinezimfanelo.

Ngasiphi isigaba uphenyo

Okwamanje, ucwaningo esigabeni preclinical, ie ingakamiswa evivinywa abantu. Kulesi sigaba, abacwaningi esetshenziswa amagundane lapho umzimba kuye kwaba allergen somoya ethize, futhi kungavimbela ukusabela kwawo nomzimba. Isinyathelo esilandelayo - ukuhlola indlela entsha ku amangqamuzana omuntu egunjini lokucwaninga esibhedlela.

Ngenxa yaleli ukuthuthukiswa, izingane abanomzimba ongezwani nezinto ezithile kuya amantongomane, isibonelo, uyokwazi ukuya esikoleni ngaphandle kokwesaba ukuthi ukudla kusuka enkantini yesikole kungase kubangele komzimba.

Ekugcineni, ososayensi banethemba lokuthi abantu abanomzimba ongezwani nezinto ezithile engase ebulalayo ingelapheka nge umjovo owodwa. Umgomo wabo oyinhloko - ukwenza lezi imijovo njengoba elula futhi lutholakale kalula, ezifana, isibonelo nje, umgomo ngokumelene umkhuhlane. Uma imiphumela yocwaningo ayaqinisekiswa, lezi imijovo Ungashintshanisa ukwelashwa ngesikhathi esifushane, okuyinto okwamanje kufanele iphendukele abanye abantu abanemizimba engezwani.

Lapho ukwelashwa sekudlulile zizokwenziwa umphakathi

Ososayensi balinganisela ukuthi kusadingeka okungenani iminyaka emihlanu yomsebenzi endaweni yokucwaninga, ngaphambi kokuthi sifeze ucwaningo abantu. Kodwa uma umsebenzi wabo ukuze uphumelele, imiphumela yayo akufanele ulinde isikhathi eside kangaka, ngoba kucatshangwa ukuthi umphumela umjovo owodwa izoqhubeka iminyaka 10-15. Ngakho, uma indlela entsha kuzothatha lonke uvivinyo ezidingekayo futhi izotholakala uquqaba, kuyoba lula ukuphila kwezigidi zabantu abanemizimba engezwani.