Ozokusebenzisa ngoba imisipha ukukhula. Yiziphi hormone ukukhula kubagijimi imfundamakhwela?

Okwamanje le hormone ukukhula kwemisipha ukukhula cishe isizathu esiyinhloko ukuthi abasubathi yesimanje bheka nje omkhulu. Ngokuphathelene ingqikithi bonke abasubathi, kuze kube sekupheleni of the 80s kwekhulu elidlule ngalokhu, azikho ochwepheshe wayengazi lutho. Sekuyisikhathi eside Wonke umuntu azi ukuthi nokusetshenziswa kwezidakamizwa ngoba sawo esiningi kuyinto ebalulekile okuyingxenye. Kodwa kulo mqondo, hormone ukukhula ngoba imisipha ukukhula ekhetheke kakhulu indaba ephathwayo, njengoba ngisho manje, ngoba amanani eqolo ukuyivumela okwamanje asikwazi ukukwenza konke. Nakuba izinga kuyazuzisa yini ngempela. Akufanele sibakhohlwe ukuthi lena ngokuphelele izidakamizwa zomthetho, ngokungafani ezinye izinhlobo steroid. Lokhu i-hormone cishe ayinayo imiphumela eseceleni, okungase kuholele izinkinga emzimbeni. Kodwa reception kuphela elungile anganikeza yalokho okuhle, ezoqhubeka isikhathi eside.

Enkabeni yalo, kuba hormone yemvelo ukuthi Asingeni ingxabano yimiphi imisebenzi yomzimba, ngakho-ke iba omunye imithi eminye esebenza ngempumelelo kakhulu ezingasiza ekufezeni izinhloso.

Ubuhlobo izidakamizwa

Esikhathini ezemidlalo imvelo imicabango yabantu kunalokho ephikisanayo mayelana izidakamizwa - kusukela enjabulo nomdlandla nesiphetho kokuqapha ngendelelo. Lokhu kungenxa yokuthi okuqanjwa kabusha noma kungekho lutho ukuba uphumelele, noma behluleka. Ngeshwa, lokhu izidakamizwa waphuma muva nje, kodwa hhayi ngenxa nokungasebenzi ngendlela yayo futhi ngenxa yokuthi le hormone i-imisipha ukukhula - ozokusebenzisa - kwabanye abagijimi nakanjani engenamsebenzi, kuyilapho abanye - ukwethula panacea. Ngesikhathi esifanayo abantu abangaphezu kwengxenye kwabadlali abasebenzisa le hormone, ukwenza into engalungile. Ukuzuza ukusebenza kuphela ngokwenza amaphutha, kodwa zinikezwe izindleko zomuthi, hhayi wonke umuntu ongakwazi ukulikhokhela.

hhayi indlela efanele yokusetshenziswa izidakamizwa kufanele kube njalo ukuze wonge imali yabo. Kunalokho, isetshenziswa empeleni athole umphumela omuhle, okuyinto nomsubathi. ukusebenza izidakamizwa akuxhomekile nje kuphela esimweni isicelo efanele, njengoba abanye imingcele angabeka ezibangela lokhu.

Abacwaningi bezokwelapha bazishaya Professional

Kabanzi ukuqonda umphumela ke emzimbeni kuzosiza biology. ozokusebenzisa, okuyinto saphathwa iziguli yabonisa ngokwanele okuxubile. Ucwaningo enkulu ayingqalasizinda, ukwenze impendulo enkulu, lwenziwe nguDkt Rudman, ngubani eyakhupha imiphumela encwadini yezokwelapha, July 5, 1990. Ngokusekelwe idatha, ososayensi kuphumelele izinyanga 6 anda izifundo yemisipha ngu 8.8%, kanti lokhu ngaphandle kokuvivinya umzimba. Futhi salotshwa ukulahlekelwa amafutha ongama e inani 14.4% ngaphandle ukuzincisha ukudla nokudla izinguquko. Naphezu kweqiniso lokuthi Embikweni wakhe, kusho umbiko, kanye nezinye izinzuzo, imiphumela enjalo akekho umuntu owayeyifuna bakwazi nokumele bakuzuze. Ingabe-ke ngenxa ezingeni eliphezulu nobuchwepheshe bale udokotela futhi ngokuzinikela kwakhe ekunakekeleni abantu kuncike, noma idatha baye bakhiwe, akekho owaziyo.

Izinhlobo ozokusebenzisa

Somatropin - hormone ukukhula womuntu. Peptides kuyisisekelo sesihlalo ozokusebenzisa, okuyinto kulindeleke ukuthi baphothule ubunikazi okufanayo acid acid ukulandelana nolimi lokuqala, ekhishwa emzimbeni. Somatropin - kuyinto akhiphe we indlala pituitary elalikade eyatholakala kusukela izidumbu, kodwa okwamanje le ndlela akuvunyelwe. Manje ngenxa ama-hormone okukhula komuntu kusetshenziswa izakhi amagciwane amaseli. Ngakho ngaleyo ndlela etholwe ukuqala izinto ngokuvamile akahlukile original adalwe hypothalamus. Kubhekiselwa kuye ngokuthi rHG (isakhi sokuzakhela ozokusebenzisa), kodwa uvame ukubizwa ngokuthi somatropin noma somatrem.

I wokukhula ongokwemvelo-hormone okuthiwa i uketshezi

ukukhula Human ngenxa yokuba khona emzimbeni we somatotropin. Ngakho, egazini besilisa okuqukethwe kwawo at 1-5 ng / ml. Kodwa lesi sibalo ngisho phakathi, ngoba emini iguquka futhi ungaya kufike ku-20 noma ngisho 40 ng / ml. Lokhu ukushintshashintsha kuncike ngabanye, futhi uma umuntu ne izinga eliphakeme lama-hormone emzimbeni ukwethula ingxenye eyengeziwe-ke, cishe, ngeke uzizwe umehluko ekhethekile, naye futhi, ngeke ubonakale ezingeni ngokomzimba. Phela, "indlela Abantu sika" ukuzimisela inqwaba hormone usasebenza. Ngakho, nomuntu obuka izinyawo akhe nezintende zezandla: ubungako bawo kumele kube isilinganiso okuningi. Lona yofuzo imuphi omunye umuntu. Kucatshangwa ngakho konke lokhu akukwazi kubhekwe kuphela indlela yeqiniso, njengoba kukhona kilomlayo, okuyinto asisho abophe usayizi izingxenye ngazinye umzimba nezinga hormone. Zonke ngamunye esimweni ngasinye.

Lokho ulawula uketshezi engokwemvelo ozokusebenzisa?

Ukuze inqubo okuhambelana endocrine indlala sise esesiqwini sobuchopho kanye nethonya wekukhula, intfutfuko kanye umzimba umzimba.

Izinga ozokusebenzisa ilawula ngokuqondile le ngxenye. By the way, kuba isilawuli ophambili kuleli cala kwezitho zobulili. Inani ozokusebenzisa futhi isidingo yayo ngoba umzimba kuchazwe hormone ezimbili peptide:

• Somatostatin.
• Somatoliberin.

Ngakho, uma ngiphoqelekile ngempela, bathola ngqo indlala pituitary. ozokusebenzisa iqala kukhiqizwa ngesikhathi esifanayo ngokushesha ngoba amasignali Micropulse, kodwa kungenziwa ngcono ngosizo ukuxhaphaza abavamile:

• peptides;
• somatoliberin;
• ghrelin;
• uketshezi androgen;
• ubuthongo enempilo;
• ukuqeqeshwa ngokomzimba;
• esiningi amaprotheni.

Ngalezi zindlela kungenzeka ukwandisa lokuhlushwa i-hormone zemvelo ukukhula okungenani izikhathi ezintathu noma emihlanu, kodwa ungakhohlwa ukuthi kuphela inhlanganisela ezinengqondo-hormone, sijime futhi ubuthongo anganika imiphumela emihle.

Lokho angakwenza

amathonya kwama-hormone ukukhula womuntu, yingakho banayo lelo gama. Ngaphezu inkanuko imisipha, futhi amanothi nomthelela omuhle eziningi nezinye izindawo zomzimba:

• It ngcono lipid yokwakheka igazi ;
• normalises izinqubo umzimba;
• kwandisa umsebenzi wocansi;
• engasenamahloni izinqubo catabolic e imisipha;
• amalunga omzimba enamandla nemisipha;
• sithuthukiswe esivuthayo fat;
• It ngesivinini ukukhula intsha (eneminyaka engaphansi kwengu-25);
• kwandisa ukunikezela edepho ka glycogen esibindini;
• kwandisa ithoni kwesikhumba;
• ngokushesha Underwear uphulukisa amanxeba kanye regenerates yakhe izicubu ezintsha;
• It kwandisa usayizi inani lamaseli isibindi, ubulili kanye nezindlala thymus.

Kuthiwa ama-hormone: Itafula yobudala

Isiqongo esiphezulu ozokusebenzisa ecela kwengu-20 edlule. Ngemva kwalokhu uketshezi liyancipha nge-avareji ka-15% eminyakeni engaphezu kwengu-10.

Ngezinye ezahlukene isikhathi amaphuzu lokuhlushwa ukuphila somatotropin ekushintsheni. Kunoma ikuphi, aba maningi ubudala, ama-hormone kancane umzimba sika odlalwa. Ithebula ubonisa ngokucacile umkhuba ukunciphisa isilinganiso ozokusebenzisa ngokuphila. Ngakho, kuyacaca ukuthi engu engcono anakekele yena nomzimba wakhe, kuyoba kusukela engu-15 kuya ku-25, futhi kungcono kakhulu ukuba uzibandakanye intsha ekuseni. Ngamanye amazwi, "le elibi nenqwaba imisipha" kuyoba ikhiqize kakhudlwana okwamanje izinkathi kunazo asebenzayo we ukukhiqizwa kwama-hormone. Kodwa lokhu akufanele kuthathwe ukuze emva kweminyaka 25, akekho ithuba ukuya ejimini futhi ubone umphumela umsebenzi, uyomane cishe enze umzamo omkhulu.

Kuhle kokusho ukuthi uketshezi hormone ukukhula has iziqongo zalo emini. ukuthuthukiswa Peak njalo emahoreni 4-5, futhi okukhulu kakhulu iqala ebusuku, ngemizuzu engaba ngu-60 ngemva ngilale.

isizukulwane indlela kanje. Hypothalamus liyala indlala pituitary okuyinto yena, iqala synthesize ozokusebenzisa. I-hormone ingena egazini uhambela kwesibindi lapho aguqulwa bese uba somatomedins. Kuyinto yalolu ketshezi futhi phakathi kwezicubu imisipha samaqanda.

Field kwesicelo lo mdlalo

hormone ukukhula ukuze abantu kabanzi abadlali nabagijimi ikakhulu 4 ezindaweni:

• setha yemisipha;
• ukuphulukiswa okusheshayo kakhulu amalunga ukuthi baye balinyazwa (kungenxa yokuthi i-hormone ngempumelelo ekwelapheni imisipha, it is ngenkuthalo esetshenziswa hhayi kuphela umkhuba amandla, kodwa futhi athletics, ibhola lomphebezo kanye football, lapho umonakalo "Achilles" kuyinto njalo kunalokho);
• evutha yamafutha amaningi emzimbeni;
• usizo yabadlali abanale ozokusebenzisa uqala wehlise ngenxa yezinguquko ezihlobene nokukhula.

Imvamisa umjovo

ozokusebenzisa Human zizosebenza kuphela uma uphuzwe kahle. Somatropin saphathwa ngaphambilini ngomjovo izikhathi 3 ngesonto, kodwa ngokushesha ochwepheshe banikeza imijovo nsuku ukwandisa ukusebenza kahle yayo futhi ukunciphisa izici ezingezinhle kokubili. Ososayensi bakwazi abuqede kwinkulumompikiswano zisetshenziswa engamele ukuqondiswa efanele kwama-hormone. Indlela ephumelela kakhulu is injected nsuku yesibili. Kuyinto ngenxa imikhuba enjalo ayikwazanga kuphela ukwandisa izinga nekhwalithi yekusebenta, kodwa futhi ukuqinisekisa ukuthi ngeke awusebenzi kwehle nozwela receptor, kungakhathaliseki ukuthi isikhathi eside yokuvuma Yiqiniso.

It is, Nokho, uma sibala into eyodwa: umkhuba imijovo Njalo ngemva kosuku olulodwa isebenza kahle kuphela uma ekudleni msubathi ayikho ngaphansi ukusikeka, futhi lo msubathi uthola lemali edingekile kilojoule ngesikhathi isisindo setha. Ngo nenkathi predsorevnovatelny Kunconywa imijovo nsuku zonke. Lokhu kungenxa yokuthi edonsa ikhalori kuyehla ngalesi sikhathi.

Isikhathi esingcono kakhulu sokuba imijovo kuyahlukahluka ngesilinganiso samakhilomitha 1-2 amahora ngaphambi noma ngemva kokuzivivinya. Kuleso simo, uma isifundo senzeka ebusuku, kubalulekile ukuba kancane ulungise inkambo ukuthatha hormone ukuze umjovo wokuqala kwenziwa ekuseni, kanti eyesibili - ukuze amahora ambalwa ngaphambi kokuba umsebenzi.

Njengoba kwaphawula ochwepheshe, ukuze uthole impumela engcono phakathi Inkambo yokwelashwa nge-hormone kungcono kakhulu ukulungisa ngokugcwele evamile ukuzivivinya umzimba wakho bese uqale kokuvakashela Igumbi ngosuku olulandelayo, kanye kokuthatha lesi imithi. Yiqiniso, lokhu kuyiqiniso kuphela ngesikhathi "umsebenzi isisindo."

i-hormone ukusebenza asebenzayo ebiziwe futhi isigamu-nokuphila ezomhlaba kusukela amahora 2 kuya ku-4. Naphezu kweqiniso lokuthi lena akuyona nengxenye-ukuphila zomuthi ngomqondo classic, esigabeni ezimatasa siyenzeka ngalesi sikhathi. Lokhu kungenxa yokuthi ngemva 4 amahora zomuthi eyeka nokucindezela uketshezi ayo ozokusebenzisa, kodwa ezingeni uhlala ephakeme cishe amahora 14. Kulesi sisekelo it is hhayi Kunconywa ukuba bafake ngesikhathi sokulala ezingeni uketshezi ayo iyona esebenzayo kakhulu ngehora lokuqala ubuthongo. Kodwa kuyafaneleka yokuthi iba namandla futhi ezijulile ukwethulwa ubuthongo umjovo liyewushona. Phakathi nale nkathi, ukushiswa fat okukhulu kakhulu, ngakho umbuzo ngasiphi isikhathi ukukwenza imijovo, iba kuyindaba yokukhathalelwa umuntu esekelwe imigomo eqondile kanye nezinhloso.

side effects

Nge zonke izikhathi ezinhle futhi eyingqayizivele ozokusebenzisa ngoba imisipha ukukhula has eziningana engathandeki side effects, okungase ukuzibonakalisa ekwenyukeni wegazi, yegilo iziyaluyalu ukusebenza, ukwanda ubukhulu izinso kanye nesifo senhliziyo, kahle kungakhuphula izinga likashukela. Endabeni eside izifundo nge umthamo omkhulu ungavela ingozi ukuthuthuka komqondo sikashukela kulezo abasubathi abanale yofuzo ngokwemvelo kulesi sifo, noma osevele uhlushwa nabo ngezigaba kokuqala.

Ngokukhethekile ithatha kahle kungakhuphula izinga likashukela. Lokhu i-hormone kunciphisa umsebenzi we-insulin. Ngakho, uma kuba indlela ukuzivikela, elikwaziyo ukuze ixwayise i ikhoma esizohlasela hypoglycemic. Noma yimuphi athlete uyazi ukuthi ngokushesha nje lapho yehlise amazinga kashukela egazini, ngokushesha kwandisa uketshezi we-hormone ukukhula. Kodwa ngesikhathi lo msubathi isetshenziswa ukudla okwakha ngesikhathi iqoqo isisindo, i-hormone kuvusa ukukhululwa kwe-insulini kanye ezinkulu. Ngakho-ke, kwezinye izikhathi kwandisa ingozi kahle kungakhuphula izinga likashukela. Futhi, kanye prolactin egazini zingandiswa, kepha wesabe kakhulu ukuthi akwenzi mqondo, ngoba abasubathi nozwelo akusiyo ezingaphezu kuka 1/3. Kodwa ngisho noma kukhona ke kulula ukusingatha ngosizo bromocriptine. Umthetho wokugcina imiphumela engemihle engase zamanje angabhekwa "carpal Umhubhe syndrome" okuyinto kubangelwa pinching izinzwa e umsele carpal.

Ukukhuluma lakamuva. Enough "ezithakazelisayo" side effect ukusetshenziswa ozokusebenzisa okubizwa ngokuthi "Umhubhe syndrome." Lesisifo ejwayelekile for labo sebenza okuningi kwi-computer, futhi isifo esithinta izinzwa libhekene ubuhlungu isikhathi eside futhi ukungabi namizwa iminwe.

Nakulokhu futhi phezu umehluko zofuzo

Nakulokhu futhi kuyafaneleka ukukhumbula ukuthi hormone ukukhula ngoba imisipha ukukhula kuthinta wonke umuntu ngendlela ehlukile. Abanye abasubathi ungazizwa nanoma imuphi umthelela umzimba, ngenxa yokuthi amasosha omzimba akhiwa, kodwa nabanye abasubathi kuba panacea yangempela. Ngakho, kukhona yanda isisindo noma fat esivuthayo senzo sibonisa izidakamizwa. Olunye ucwaningo athakazelisayo atholakala ukuthi impendulo ozokusebenzisa, lokhu kuncike izinga kwe-testosterone.

ozokusebenzisa futhi Ama-anabolic steroid

Kubalulekile nokukhumbula okulandelayo: ukuze ayibulale fat ngokweqile noma ukwandisa isisindo somzimba, akwanele ukuba aphuze nje hormone ukukhula. Ama-steroid kulokhu kuyoba ngaphezu kakhulu. Ukusetshenziswa ebaluleke kakhulu i-testosterone ozokusebenzisa, amalungiselelo akhethekile "Stanozol", "trenbolone" noma "Methandrostenolone".

Ngakho, uma nomsubathi kuyinto ndlela wemfanelo kakhulu ukukhethwa umthamo zomuthi, hormone ukukhula kungakusiza ufinyelele imiphumela oyifunayo futhi akubangi izigigaba ezingezinhle. Kodwa ngisho noma benza zenzeka cishe emuva. By the way, plus konke kuwufanele unezela ukuthi abacwaningi bathola, futhi abanye umphumela anti-ukuguga le-hormone emzimbeni (kanye nabanye nemiphumela emihle).

Ngokwemvelo, kufanele kuholele kuphela impilo enempilo futhi uqede yonke imikhuba emibi, futhi esimweni imithi futhi wenze konke okusemandleni ukuba uthintane onguchwepheshe noma udokotela.

Ngakho manje unayo umbono walokho hormone obangela ukukhula, kukanjani zamagama alo futhi ukuthi lingangisiza kanjani ekufezeni umgomo. Nakanjani kudingeka bathenge imithi yokwelapha kuphela izikhungo ezikhethekile, okuyinto unawo wonke amaphepha adingekayo namalayisense. Naphezu kweqiniso lokuthi le ezilimele noma kudedelwa eshalofini yokuphila hormone ukukhula kakhulu akanamandla imiphumela emibi emzimbeni, ukusetshenziswa umkhiqizo elinjalo futhi ngeke, futhi imali ngesikhathi esifanayo uzobe esichithekayo. Ukunamathela imithetho elula mayelana ukuthenga yayo kanye nokusetshenziswa kungaba kalula futhi ngokushesha ngangokunokwenzeka ukuze kuzuzwe imiphumela oyifunayo.