I-Cushing's syndrome: izimpawu, ukuxilongwa, ukwelashwa

I-Cushing's syndrome ivela uma kwenzeka ukwanda kwezinga le-glucocorticoids ku- cortex ye-adrenal. Lesi sifo sivame ukutholakala kwabesifazane. Isizathu esivame kakhulu sesifo ukukhiqizwa kwe-ACTH (i-adrenocorticotropic hormone) ye-pituitary, ethinta umsebenzi we-acteal cortex futhi iholela ekwandeni izinga lama-hormone. Ngokuvamile ukukhululwa okukhulu kwe-hormone ye-adrenocorticotropic kukhishwa yisifo se-pituitary, futhi kwezinye izimo ngesifo sezinye izingxenye. Lesi sifo singakhula ngokulawulwa kwemithi emikhulu yama-steroid amalungiselelo aqukethe i-cortisone, noma ama-agent ane-ACTH (evame ukusetshenziswa ukunciphisa umsebenzi wokuzivikela ngomzimba ngesikhathi sokufakelwa komzimba).

I-Cushing's Syndrome: Izimpawu

Impilo jikelele kanye nobulili kuthinta izimpawu zalesi sifo. Izimpawu ezivamile zalesi sifo yilokhu:

• Inzuzo yesisindo esheshayo. Amafutha athuthukile ahlala ebusweni futhi ikakhulukazi emhlane ongaphezulu;
• Stria (welula amanothi) esiswini, esifubeni, izingalo namathanga;
• Ukubonakala kokulimaza, ukuncibilikisa isikhumba;
• Amanxeba aphilisa kabi;
• Inqubo ephuthumayo yokuphulukisa emva kwezifo ezithathelwanayo eziyingozi;
• Ubuthakathaka, ukukhathala;
• Ukukhathazeka, ukulala;
• Ukuzwela ngokweqile;
• Izinsizwa;
• Ukunciphisa inkumbulo namakhono engqondo;
• Kwabesifazane, umjikelezo wokuya esikhathini ukulibaziseka;
• Ukungahambisani ne-glucose, okuholela ekushukela kwesifo sikashukela;
• I-hypertension.

I-Cushing's syndrome: ukuxilongwa

Ukuxilongwa kwangaphambili kungenziwa ngesisekelo sezibonakaliso zesifo. Ukuze uthole ukuxilongwa okunokwethenjelwa, ucwaningo olwengeziwe luyadingeka, ngosizo lwezimbangela ezibangelwa i-Cushing's syndrome. Ukuze wenze lokhu, kuyadingeka ukuthi uhlaziye umchamo bese unquma izinga le-cortisone. Ucwaningo oluqhubekayo lubonisa ukuhlola isiguli ngokuhlolwa kwe-dexamethanosone, lapho isiguli sidla amagremu amabili. I-Dexamethasone, futhi ngemuva kwamahora angu-9 izinga le-cortisone eplasma lilinganiswa.

Ukunquma izimbangela ezingabangela i-Cushing's syndrome, izinga le-ACTH lilinganiswa. Ngakho, izinga eliphakanyisiwe le-hormone likwazi ukukhuluma ngokungasebenzi kwemithi, futhi kakhulu kakhulu - mayelana nokuphazamiseka kwe-hypophysial.

I-Cushing's syndrome: ukwelashwa

Ukwelashwa okuvame kakhulu futhi okuphumelelayo kwalesi sifo kuwukukhetha okwenziwe yi-adenomectomy transsphenoidal. Uma izifundo zikwazi ukucacisa indawo eqondile ye-tumor ye-pituitary gland, ukungenelela kwe-neurosurgical kwenziwa. Le ndlela ayikwazi ukusetshenziselwa uma isiguli sinesimo esibi kakhulu saleso sifo noma sinezibalo ze-pathologies.

Enye indlela yokwelashwa ukubhujiswa kwezingqungquthela eziyingozi. Ngokusungulwa kwezidakamizwa ze-sclerosing, kungenzeka ukuthi ususe imithi engenawo amandla. Inqubo yenziwa ngokusebenzisa izindlela ze- ultrasound ne-CT.

Kukhona futhi indlela yokwelapha i-Cushing's syndrome, njengokwelashwa kweproton. Le ndlela isetshenzisiwe uma kungekho izindlela ezinokwethenjelwa zesisu se-pituitary gland. Kungenzeka futhi ukuthi ukwelapha lokhu okuphathelene nokukhubazeka ngokwemithi. Kulesi simo, imali isetshenziselwa ukuvimbela ukukhiqizwa kwe-ACTH. Ukwelashwa okuyisimiso okuhloswe ngazo ekwelapheni izinzwa, isifo sikashukela, kanye ne-osteoporosis nakho kwenziwa. Kwezinye izimo, indlela yokwelapha imishanguzo ingasetshenziswa. I-Cushing's syndrome ihilela ukuthatha izidakamizwa , ama-bisphosphonates, amavithamini neminye imithi. Lesi sifo kulula kakhulu ukuphatha futhi lapho kuqala ukwelashwa izimpawu ziphela kancane kancane.