-hemoglobin Glycosylated - ukuhlolwa kuphoqelekile sitholakele ngifundise ngesifo sikashukela kanye nokuhlola ezingeni isinxephezelo yayo

Zokwelapha kukhona izimo lapho ukuba nokuhlola ukusebenza imithi zikashukela-ukwehlisa, kanye nokwanela ukwelashwa ebekiwe iziguli sikashukela mellitus kungase kube nzima. Kubonakala sengathi umuntu azizwa kahle, kuphela ngokukhuleka nangokuzila ukudla glucose in evamile yakhe, kodwa yini amathuba yezinkinga kule nesineke? Phela, inani glucose egazini kuphela esikalini ngesikhathi kulesi sifundo, lo sibalo esisodwa.

Ngezinye izikhathi ukwandisa amazinga igazi glucose ezitholakala kubantu enempilo, isibonelo, ngemuva kokuthola semali carbohydrate noma ukucindezeleka ngokomzwelo nasendleleni yokucabanga ngokweqile. On ushukela amazinga kungathinta edonsa kunemithi noma amaphilisi owaphuzayo, ezifana nokukhandela imbeleko temlomo, abanye isisu, izidakamizwa zengqondo. Kuzo zonke izimo ezinzima basisize i Ukuhlaziywa endocrinology ngoba elithwala umoya-mpilo glycated, bebheke uphenyo, yena ubizwa ngokuthi HbA1c.

-hemoglobin Glycosylated - lokhu uxhumano sekukhona molecule glucose ne-hemoglobin A, ngokuvamile le nqubo ithatha indawo ngokuqhubekayo abantu enempilo. Inani i-hemoglobin ubhekene glycation - 5-8%. Ngo iziguli sikashukela, lesi sibalo ukhula ngokuphindwe izikhathi ezingu-2-3 kanye iqhubeka kulo ukuphila egazi abomvu, okungukuthi, izinsuku 120. Ngoba igazi iqukethe kokubili corpuscles abasha elibomvu elivuthiwe, ngakho-ke, kuthathwe isilinganiso seminyaka yobudala ingqamuzana elibomvu, okuyinto ilingana isikhathi ingxenye yokuphila kwakhe - ezinsukwini ezingu-60.

Glycosylated elithwala umoya-mpilo, izinga okuyinto 4-6.1% wezindleko-hemoglobin ezingeni, kubonisa glucose isilinganiso izinyanga ezimbili kuze ukuhlolwa igazi. Ngakho-ke, kungenzeka ukuthola ukuthi ukwanda eside e-glucose noma ngaphakathi 2 izinyanga lokhu Inkomba kwaba esimweni esejwayelekile. Ukuhlanganisa emkhatsini HbA1c kanye glucose egazini wazibonakalisa kweminyaka yocwaningo, empirically uzimisele ukuthi ukwanda igazi glucose at 1.59 mmol / l ngayinye 1%-hemoglobin ngaphansi glycation.

Kwezinye izimo, isivivinyo engabelwe-hemoglobin glycated?

- I- ekuxilongweni sikashukela futhi ekuboneni izinga yayo isinxephezelo;

- ukuqapha ekwelapheni ejenti hypoglycemic ;

- ukunquma ingozi yezinkinga semithambo sikashukela;

- kuzo zonke izimo of kahle glucose ukubekezelelana kanye ukuxilongwa zangaphambi sikashukela;

- abesifazane abakhulelwe basengozini yokuba nesifo sikashukela.

Ukuhunyushwa ukuhlolwa imiphumela sikashukela:

Ukuze 5.8% - isifo sikashukela kanye inzuzo.

Kusukela ngomhlaka 8 kuya ku-10% - ngokwengxenye ihlawulelwa sikashukela.

Over 12% - ukulimala isifo esibi.

Endocrinology zama ukukhetha yokwelapha ukuze hemoglobin glycated kwaba ku ezahlukene kusukela 7 kuya kwezingu-8%. Lapho ebekiwe ngokufanele ukwelashwa aphakeme HbA1c level eza emuva evamile ngenyanga eyodwa emva ukulungiswa.

I-American Diabetes Association uncoma ucwaningo olwenziwe akukho kancane njalo kuka njalo emva kwezinyanga eziyi6. ERussia, ukuhlaziywa HbA1c inikezwe zonke iziguli ethola insulini kanye hypoglycemic izidakamizwa, kanye njalo ezinyangeni ezi-3. Ngokusho ezingeni-hemoglobin HbA1c kungenziwa yahlulelwe ngabe awokuthi zokugula ngesineke microvessels ngwengwzi, ukulimala kwezinso, futhi nezinzwa.

Kwezinye izimo, kungenzeka ukuhlanekezela ukuhlaziywa HbA1c?

Waqanjelwa aphakeme Imiphumela waphawula ne bandise izindlela-hemoglobin fetus egazini nensimbi ukuntula igazi. izinkomba Amanga Kutholwe ukwehla ukwa ngenxa hemolysis zama-erythrocyte ngemva kokumpontshelwa igazi igazi noma ezophe.

Ukuhlaziya i-hemoglobin glycated babelwe kancane ngaphezulu (1 inyanga ngayinye) iziguli Yiqiniso angajwayelekile lesi sifo, uma isifo ezinzima concomitant, abesifazane abakhulelwe abanesifo sikashukela ukuvimbela ukuthuthukiswa isifo ku-fetus.