Izidakamizwa hypoglycemic isizukulwane esisha kanye ngezigaba zabo

Abantu abanesifo sikashukela Uhlobo II sikashukela kufanele sihlale njalo siqaphele ezingeni glucose egazini. Kuphela uma nemingcele evamile Ungaphila impilo evamile. Lapho kashukela liphume, udokotela wakho angase akunikeze wokulungiselela okukhethekile ukuzinza kwesimiso lesiguli. Iningi izidakamizwa kuleli qembu ekhiqizwa amaphilisi. Yonke imithi (antidiabetic) zihlukaniswe sulfonylurea okunye, prandial glucose nabalawuli, biguanides, alpha-glucosidase inhibitor futhi insulini sensitayzery. futhi inhlanganisela kusho liyatholakala nasemiBhalweni Pharmacy.

sulfonylureas

ukwelashwa izidakamizwa baqala zaphathwa iziguli sikashukela ohlobo II ngasekuqaleni 60 leminyaka eledlule. Namuhla nemikhiqizo sulfonylurea athandwa kakhulu. Imithi ahlukaniswe isizukulwane sokuqala nesesibili. Eyokuqala practice yesimanje kuyaqabukela esetshenziswa. Izidakamizwa kule hypoglycemic iqembu ebekiwe iziguli isisindo umzimba ezinkulu, uma kukhona non-insulini sikashukela engaphansi mellitus. Ukuswelakala kokusebenza ngokuhlanganyela ukunxeshezelwa carbohydrate umzimba kuyinto grandstanding ngqo ngenjongo sulfonylurea nemikhiqizo.

izidakamizwa Antidiabetic isizukulwane esisha wadala ngesisekelo the sulfonylureas ayikwazi ukusetshenziswa njengesilwane izindlela ezimele yokwelashwa. Imithi yokwelapha aphelele kuphela. Nokho, indima esemqoka udlalwa yi-ekudleni. Uma isiguli ngeke udle ukudla isithelo esenqatshelwe ngenkathi ukuphuza amaphilisi, ukwehlisa ushukela egazini, yalokho okuhle kungalindeleka.

Nakani! ejenti hypoglycemic engamiswanga ukuba iziguli insulini kanye nesifo sikashukela pancreatic. Awukwazi ukusebenzisa imithi le izingane iqembu, futhi abesifazane abakhulelwe kanye lactating.

"Glipizide"

Ukulungiselela iphathelene yesibili sulfonylureas isizukulwane. Esebenzisa inkanuko insulini okukhiphayo kusukela amanyikwe ka ezisebenza asebenzayo beta-amaseli, futhi ilawula inani glucose kumaseli kweziguli amafomu nokulinganisela okunzima sikashukela insulini nasekuthengeni. I nomuthi is edayiswa Pharmacy ngesimo amaphilisi, ngamunye equkethe 0,005 g lomcebo asebenzayo. Ukulungiselela "Glipizide" iqala ukwenza ngemva kwemizuzu engu-30 ngemva kokuphathwa nangemva kwamahora angu-24 yaphela kusuka emzimbeni.

Umthamo zomuthi Kumiswa udokotela ngamunye. Noma yimuphi izidakamizwa hypoglycemic kuyabekwa kuphela emva kokuxilongwa. Udokotela kufanele usungule ephelele isithombe emtholampilo. kokuqala umthamo wansuku zonke kumele singeqi 0,005 g (iphilisi elilodwa). Emacaleni angu-olunzima isiguli kungathatha amaphilisi 2-3 ngesikhathi. esiphezulu I umthamo wansuku zonke akufanele idlule 0.045, izibhebhe zithathwa imizuzu engu-30 ngaphambi kokudla. Ngo aphuma insulini, amazinga igazi glucose kuyadingeka ukulawula sezinsuku ezimbalwa zokuqala.

Imiphumela engemihle uma usebenzisa izidakamizwa "Glipizide" cishe lingekho. Ezimweni ezingavamile, kungenzeka ubuthakathaka, nesiyezi. enkingeni ababhekene nesimo esinje kungabaduduza kalula aqedwa Oqondisa umthamo. Ngokuvamile imiphumela emibi zenzeka ezigulini esezikhulile. izidakamizwa Antidiabetic isizukulwane esisha okuhloswe ngayo ukwenza ngcono impilo yabantu abanesifo sikashukela. Noma yimuphi ukusabela ezingemnandi zinyamalale ezinsukwini ezimbalwa ngemva Ukuqalwa yokwelapha. Contraindication ukwamukela izimali "Glipizide" kuyinto ukukhulelwa futhi isici esiyingqayizivele sulfonamides. Izingane imithi futhi ayizange inikezwe.

"Gliquidone"

Enye ejenti hypoglycemic, esiphathelene amagama ahlobene of sulfonylureas. Njengoba phansi nokucindezelwa ngezindlela zokuthi owedlule, it ezizokhuthaza ukukhiqizwa kwamangqamuzana insulin beta amaseli kwamanyikwe futhi kuthuthukisa insulini ukuzwela kwezicubu neuropathy. Kusho "gliquidone" libhekene nomphumela omuhle futhi ikhumbuleka isikhathi eside. imithi eminingi (hypoglycemic) imbangela hyperinsulinemia. Yini engase ishiwo nemithi "gliquidone".

Umuthi itholakala Pharmacy amaphilisi. Yabela ke iziguli Uhlobo II sikashukela, futhi iziguli esezikhulile okungekho yokwelapha yokudla akukuniki yalokho okuhle. Umthamo kunqunywa esekelwe izici ngabanye lomuntu, kanye isithombe yayo emtholampilo. ubuncane umthamo nsuku zonke 15 mg, esiphezulu - 120 mg. Tablets bayiswa phambi nje ngokudla. Ngo amafomu onomoya omnene sikashukela, iphilisi elilodwa kuphela ngelanga. thatha izidakamizwa kancane kaningi 2-3 izikhathi ngosuku.

Imiphumela engemihle evela eyamukelayo kusho "gliquidone" khona, kodwa emuva. Ngesikhathi sokuqala ukwelashwa kungenzeka ezigulini pruritus nesiyezi. izimpawu ezingemnandi zinyamalale ngakusasa ngemuva kokuqala ukwelashwa. Khansela isidakamizwa kuphela uma kwenzeka ukusabela okukhulu nomzimba. ukungabekezelelani ngamunye kwenzeka njalo. amalungiselelo hypoglycemic salolu chungechunge ongabekiwe iziguli nge Uhlobo lokuqala sikashukela. Phakathi ukwelashwa, akumelwe sikhohlwe ukulawula likashukela egazini lakho. Uma izibalo kuyoba ephakeme kunokuvamile, kufanele uxhumane nodokotela ngubani kuzoshintsha lwemithi yokwelapha.

Lapho hhayi prescribers sulfonilmochevny?

Predkomatoznoe izwe, ikhoma sikashukela kuyinto contraindication sina eya endaweni phezu ukuthaka imithi isisekelo sulfonilmochevny. Ayisetshenziswa temlomo ejenti hypoglycemic kulolu chungechunge futhi phakathi nokukhulelwa kanye lactation, kungakhathaliseki ukuthi aba namuphi umphumela osekuzuziwe ngaphambili.

usongo olukhulu empilweni yomuntu, abaphethwe Uhlobo II sikashukela, unazo ukuhlinzwa. Ukuze uthuthukise nesineke amabutho ukuphepha, nemikhiqizo sulfonilmochevny kukhanselwe okwesikhashana. Balandele lesi simiso e izifo ezithathelwanayo. Ukugcizelela main ibekwe ku ekwelapheni lesi sifo esigabeni oyingozi. Njengoba nje isiguli uzizwa emuva evamile, zingase a imithi emisha antidiabetic ebekiwe. Uma contraindications ukusetshenziswa sulfonilmochevny kungenjalo, ungaqala ethola izidakamizwa kulolu chungechunge.

Prandial glucose nabalawuli

Kwakuthinta izifundo eziningi ama-amino acid, ngokuhamba okuyinto okuye kwabonakala indima yabo insulini uketshezi. Kwatholakala ukuthi analogs benzoevoy acid phenylalanine ube isinyathelo hypoglycemic. Prandial glucose nabalawuli angakwazi ukulawula uketshezi insulin ngokushesha ngemva kokudla. Futhi kwaba kulesigaba amazinga okwanda kwegazi glucose. New hypoglycemic ejenti abe umphumela wangaleso sikhathi. Ngakho uzithatha ngesikhathi kuphela noma ngemva kokudla. Ukusetshenziswa kwezidakamizwa ukuze kuvinjelwe okungalungile.

Naphezu kweqiniso lokuthi Ukwahlukaniswa ejenti hypoglycemic zihlanganisa prandial glucose nabalawuli, bona azisetshenziswa njalo kakhulu. Imithi kulolu chungechunge ukukhiqiza umphumela wangaleso sikhathi, ngakho-ke asikwazi yaphathwa ukwelashwa, uhlobo ezinzima sikashukela II.

"Novonorm"

Oral izidakamizwa hypoglycemic elitholakala Pharmacy amaphilisi. Umuthi ezinqunyiwe lapho yokwelapha yokudla nokuvivinya umzimba unganikezi Imiphumela ezanele. Iziguli Type II, ngokuvamile isifo sikashukela ukuthatha "Novanorm" lihambisana namanye amanxusa antidiabetic. Ngakho, Iziguli ziyakwazi ukuqhubeka eduze kakhudlwana ukuqapha ezingeni glucose.

Tablets "Novanorm" kunilungele sisetshenziswa ndawonye Ukudla. Umuthi esithathwayo ngomlomo ngaphambi kokudla kathathu ngosuku. Ezimweni ezingavamile, umthamo kungenziwa lenyuke. Iziguli abanemizimba snacking noma ukungadli ngezikhathi zokudla, kufanele babonane nodokotela mayelana "Novanorm" ngokunemba ukuthatha amaphilisi.

Njengoba sekushiwo, ejenti hypoglycemic sikashukela kungukuthi njalo esimisiwe. Ezinye uphathe ukulawula ezingeni glucose egazini kuphela ngokudla. Tablets "Novanorm" ingasetshenziswa uma ehluleka ukuyilawula yase glycemia okwesikhashana. imiphumela emibi izidakamizwa awatholatholakali futhi yesikhashana. Isiguli bangezwa nesicanucanu ubuhlungu besisu. Ukungakhululeki kudlule masinyane. Khansela isidakamizwa kuphela endabeni ukungabekezelelani ngabanye. Amaphilisi contraindicated "Novanorm" izingane, abesifazane phakathi nokukhulelwa kanye lactation, in iziguli ezinzima ukungakhuli hepatic.

biguanides

Ukwahlukanisa izidakamizwa antidiabetic kufanele sifake izimali eziphathelene iqembu biguanide. Imithi kulolu chungechunge akuzona onesibopho ezishukumisayo insulin uketshezi. Naphezu kwakho konke lokhu, biguanides zidlala indima ebalulekile ekwelapheni uhlobo II sikashukela, njengoba anda glucose neuropathy ukusetshenziswa ezicutshini zomzimba. Imikhiqizo dannog eschestva isibindi kakhulu ziyancipha. Biguanides kungaba kakhulu ukunciphisa amazinga igazi glucose. Kwezinye izimo kungenzeka ukufeza zonke izinkomba evamile. I Izimo eziyinhloko ukusetshenziswa kwezidakamizwa ezifana wombuso predkomatoznoe e iziguli sikashukela. Okumele kuqashelwe iqondiswa ejenti hypoglycemic iziguli isizukulwane 3rd ukuba nokuthambekela utshwala, kanye kahle umsebenzi sesibindi.

"Metformin"

izidakamizwa Oral hypoglycemic bohlanga biguanide. Umuthi itholakala Pharmacy amaphilisi. The main isithako eyeka ukumuncwa glucose esiswini, kanye nezinkulu ukwanda glucose ukusetshenziswa ezicutshini neuropathy. Hypoglycemic ukusabela amaphilisi "Metformin" musa abangele. Umuthi iqondiswa iziguli sikashukela soHlobo II abangenalo ukuthambekela ketoacidosis. Tablets ingaphinda iqondiswa lihambisana insulini ukuba iziguli ukukhuluphala.

Kuye ezingeni glucose egazini, udokotela ngamunye ukusetha umthamo imithi. Ukwelashwa usungaqala nge yokwamukela iphilisi elilodwa ngelanga (500 mg). I ukwenyuka kancane umthamo kungaqala kuphela amasonto kuphela ngemva ezimbili ukwelashwa okuqhubekayo. esiphezulu I umthamo wansuku zonke kumele singeqi amaphilisi 6. Iziguli abaneminyaka engama-70 akufanele kuthathe ngaphezu 2 amaphilisi ngosuku.

Hypoglycemic ithebhulethi ukwakhiwa kuthiwa contraindicated kubantu nge sezinso kahle. Uma kukhona isifo engaholela encishisiwe izinso umsebenzi, amaphilisi "Metformin 'kukhanselwe okwesikhashana. Awukwazi uzithatha enkathini ukulungiswa emva kokuhlinzwa. Contraindication kuyingozi acute utshwala ubuthi.

Alpha-glucosidase inhibitor

Leli qembu izidakamizwa ukuthi ungakwazi ukuvimba ukukhiqizwa ethize enzyme emathunjini (alpha-glucosidase). Ngalesi uchungechunge ukwakhiwa kakhulu ziyancipha ukumuncwa core carbohydrate ezifana isitashi, sucrose, futhi maltose. Endabeni reception efanele ngemithi yanamuhla antidiabetic kuleli qembu nhlobo engemihle. ukungakhululeki ngingekho Ngokuphelele amathumbu yisisu.

Alpha-glucosidase inhibitor kufanele kuthathwe kanye umthamo lokuqala ukudla. Eziswini kanye ukudla, izingxenye imithi ukunikeza nomphumela omuhle hypoglycemic. Imithi kulolu chungechunge zingafundwa kanye esebenzisa sulfonylurea noma nge-insulini. Ingozi kahle kungakhuphula izinga likashukela iyakhula.

"Miglitol"

ejenti hypoglycemic bohlanga-alpha-glyueozidaz inhibitor. Tinkondlo iziguli uhlobo ngokulinganisela sikashukela II kwenzeka ukuthi umsebenzi eyanele nokudla akayinekezi yi efanele. Tablets "miglitol" ndlela iphumelela kakhulu lapho kusetshenziswa esiswini esingenalutho. Ezimweni ezingavamile, eminye uqoke namanye amanxusa temlomo hypoglycemic. Ukwahlukanisa kusho ukulawula ezingeni glucose egazini seyenziwe ngenhla.

izingxenye Main "miglitol" izidakamizwa egxile ngokuphelele phakathi kwezicubu nge mbandela ethola ngemithamo ongaphakeme (1-2 amaphilisi). Ngezinye umthamo 50 g ukumuncwa 90%. Isithako esebenzayo excreted ngu izinso zinjalo. izidakamizwa Antidiabetic engamiswanga izingane kanye nabesifazane abakhulelwe kanye lactating. Contraindication kukhona ezingamahlalakhona wamathumbu isifo, kanye hernia ezinkulu. Imiphumela engemihle uma uthatha amaphilisi "miglitol" awavamile. Kube khona izindaba komzimba nezinto ezifana ukuqubuka futhi ukulunywa.

Kuhlanganiswe ejenti hypoglycemic

Ezimweni eziningi, ekwelapheni uhlobo II sikashukela iqala monotherapy. izidakamizwa engeziwe ezingahle zinqunywe kuphela uma ukuphathwa akukuniki umphumela efanele. Inkinga wukuthi omunye izidakamizwa akusho ngaso sonke isikhathi ukumboza izinkinga eziningana ezihlobene sikashukela. Miselela izidakamizwa eziningi amakilasi ezahlukene zingahlanganiswa nomunye ejenti hypoglycemic. Ukwelapha okunjalo kungaba ivikeleke nakakhulu. Phela, kakhulu kwanciphisa ingozi nemiphumela engathandeki yalawo maphilisi. Indlela ephumelela kakhulu, ngokusho kodokotela, luyinhlanganisela metformin futhi thiazolidinediones futhi sulfonylureas futhi metformin.

izidakamizwa Kuhlanganiswe eyenzelwe ekwelapheni uhlobo II sikashukela bayakwazi ayeke ukuqhubeka hyperinsulinemia. Ngenxa yalokhu, iziguli zizizwe kangcono kakhulu futhi bayakwazi ulahlekelwe isisindo kancane. Ezimweni eziningi, isidingo soshintsho yokwelapha insulini iqedwe ngokuphelele.

Omunye ethandwa kakhulu izidakamizwa elihlangene antidiabetic kuyinto "Glibomet". Dedela nomuthi ngefomu ithebhulethi. Bamiswa ngemva ukuphathwa odlule akazange abonise imiphumela emihle. Ungayisebenzisi le izidakamizwa ukuze aphathe abantu abanesifo sikashukela sohlobo kuqala. Amaphilisi contraindicated njengoba abantu kahle isibindi umsebenzi noma esingamahlalakhona kwezinso. Izingane nabesifazane phakathi nokukhulelwa kanye lactation izidakamizwa aluboniswa.

"Glibomet" amaphilisi babe eminingi engemihle. Zingadala nohudo, ukucanuzela kwenhliziyo, isiyezi. Mancane amathuba okuthi ukuthuthukisa komzimba ezifana ukuqubuka kwesikhumba futhi ukulunywa. Ukusebenzisa izidakamizwa Kunconywa ngokuqinile on kadokotela.