I kwesinye isiqhingana esigcwele ka-Langerhans kwamanyikwe. Amasosha Omzimba emangqamuzaneni neziqhingana ka-Langerhans

Ngamunye kwesinye isiqhingana esigcwele ka-Langerhans wenza kakhulu, kubaluleke kakhulu wonke umzimba. indima Its main - kuyinto ukulawula okuqukethwe carbohydrate igazi.

Umlando yokutholakala

I kwesinye isiqhingana esigcwele ka-Langerhans waba owokuqala owachaza lesi ngo-1869. Owathola lezi zokwakheka ezibalulekile elise kwamanyikwe (ikakhulukazi umsila ingxenye yayo), kwaba mfundi osemncane Rudolfa Virhova - Paul Langerhans. Nguye owokuqala kuhlolwa cluster ngesibonakhulu amaseli, okuyinto by isakhiwo sabo morphological kuyehluka kuneminye izicubu pancreatic.

Kwatsi emva kwaloko yathola ukuthi ama-Langerhans neziqhingana endocrine umsebenzi wenziwa. Ukutholakala kwaleli qiniso eyenziwe KP Ulezko-Stroganov. Ngo-1889 kwaba okokuqala isixhumanisi phakathi kokunqotshwa zesiqhingi ka-Langerhans kanye nokuthuthukiswa isifo sikashukela.

Yini kungaba kwesinye isiqhingana esigcwele ka-Langerhans?

Okwamanje, lesi sakhiwo ibilokhu wafunda kahle ngokwanele. Manje owaziwa ukuthi lokhu kumiswa has ezihlukahlukene. Okwamanje, siyazi labo ezilandelayo:

• -alpha amaseli;
• amaseli beta;
• delta amaseli;
• kk-amaseli;
• Epsilon amaseli.

Kuyinto ngokusebenzisa lokhu kuhlukahluka ngokunikeza kumaseli abo kwesinye isiqhingana esigcwele enze yonke imisebenzi eliyifa lawo.

Alpha-amaseli

Lolu hlobo imayelana 15-20% of kwesinye isiqhingana esigcwele etholakalayo. Injongo eyinhloko ye-alpha-amaseli kukhiqizwe glucagon. Lokhu i-hormone has a imvelo lipid kanye kuyinto eyinqaba insulini isitha. Lapho ngidedelwa ejele, glucagon iqondiswe isibindi, lapho ixhumana receptor othize, ulawula ukukhiqiza glucose ngu glycogen ukuphuka.

amaseli Beta

IziQhingana Langerhans ezihlukahlukene kukhona ezivamile. akhawunti Bona cishe 65-80% wezindleko. Manje luthole ukuthi umsebenzi wabo oyinhloko ukuthuthukisa omunye hormone ezibaluleke kakhulu - insulini. Le into kuyinto omelene we glucagon. Ukhuthaza ukusebenza glycogen kwetinhlavu kanye uyibeka esibindini nemisipha. Ngenxa yalokho yale nqubo kuyimali Ukwehla glucose egazini.

Delta amaseli

IziQhingana Langerhans kwamanyikwe yalolu hlobo azisenzeki kaningi. Ziyakwazi% 2-10 kuphela wezindleko. Manje izici zabo obusebenzayo baziwa. Kwatholakala ukuthi lezi amaseli synthesize somatostatin. Umsebenzi we ketshezi eziphila abakhuthele kuyinto ukucindezela isizukulwane somatotropin, somatotropin futhi i-hormone thyrotropin-lokukhululwa. Okusho ukuthi, ku le ngxenye futhi anterior pituitary ke izenzo ngqo.

PP-amaseli

kwesinye isiqhingana esigcwele Ngamunye Langerhans yohlobo abathintekayo kulo kwenaba ka polypeptide pancreatic. Kuze kube sekupheleni umsebenzi walo engakaze wafunda. Okwamanje, lapho udumo property abacindezela ukukhiqizwa juice pancreatic. Ngaphezu kwalokho, umphumela walo kuyasiza uphumule imisipha abushelelezi esinyeni nenyongo. Eminyakeni yamuva ngempela ngenkuthalo wafunda ukwencika ezingeni ukukhiqizwa leso sidakamizwa kumiswa izimila ebulalayo. Umphumela bathola ukuthi ukuthuthukiswa babo yanda ezingeni polypeptide pancreatic. Ngakho yalolu ketshezi eziphila abakhuthele kungase kubhekwe njengokwelapha umaka kuhle izimila abulalayo kwamanyikwe.

Epsilon amaseli

Lezi neziqhingana ka-Langerhans kukhona njalo kakhulu. Of ukubala inani engaphansi kuka-1%. Umsebenzi oyinhloko amaseli onjena ukukhiqiza ihomoni okuthiwa yi ghrelin. Lokhu kwaziswa abaphuma njalo seliphindeke izikhathi inombolo enkulu imisebenzi, kodwa iningi wafunda umqondo walo nomthelela iphango.

Mayelana zokugula iziQhingana Langerhans

Hlula lezi zakhiwo ezibucayi ine phezu umzimba nemiphumela kakhulu ezimbi. Esimweni lapho ukukhiqiza amasosha zesiqhingi ka-Langerhans, inombolo lokugcina ngokuqhubekayo encishisiwe. Hlula ngaphezulu kuka-90% amaseli kunciphisa ukukhiqizwa insulini ezingeni eliphansi kakhulu. Umphumela ukuthuthukiswa ezinjalo izifo eziyingozi ezinjengesifo sikashukela. Amasosha Omzimba ukuze Islet amaseli ngokuvamile kwenzeka iziguli ngokulinganiswa ayemncane.

zikhubazeke labantu amaseli uyakwazi gormonprodutsiiruyuschih imbangela ukuvuvukala kwamanyikwe - pancreatitis.

Indlela ukusindisa amaseli kwesinye isiqhingana esigcwele?

Kuyodingeka unakekele kwamanyikwe lonke iyonke. Okokuqala kubalulekile ukuba ayiyeke le ukweqisa uphuzo oludakayo. Iqiniso lokuthi banayo ku kwamanyikwe konke ukudla nomthelela omubi kakhulu. Endabeni ka nokunwetshiwe utshwala kubantu kwenzeka futhi iqhubeka pancreatitis, eyagcina kungaholela eside ukushaqeka kwesinye isiqhingana esigcwele amaseli.

Ngaphandle oludakayo umphumela ngokwanele omubi kwamanyikwe has a semali -ukudla ezilwane. Kulokhu, isimo uzobe esebenzisa isihluku esimweni nangaphambi kokuba isiguli sibe idili isikhathi eside Akadlanga lutho.

Esimweni ukuthi izigaxana pancreatic seluvele inqubo ezingamahlalakhona ukuvuvukala, kubaluleke kakhulu ukuba ahlole onguchwepheshe - udokotela noma gastroenterologist. Imininingwane amakhono odokotela liqoke Yiqiniso okunengqondo ukwelashwa, ezingasetshenziswa kakhulu ukubambezela ukuthuthukiswa izinguquko sokugembula. Ngemuva kwalokhu izobanjelwa amanyikwe ultrasound unyaka ngamunye, okuyinto eyenziwa lihambisana nezinye izitho we komgodi ongaphakathi kwamathumbu. Ngaphezu kwalokho, kubalulekile ukuthatha ukuhlaziywa kwamakhemikhali kwegazi kokuqukethwe yayo Amylase.

Ukuze ubone ukuthi ukuqala pancreatitis okungamahlalakhona, ngaphezu izifundo laboratory nowezinsimbi, kuzosiza emtholampilo. Uphawu oyinhloko lesi sifo ukubukeka ubuhlungu kwesokunxele quadrant engenhla. Ngaphezu kwalokho, lokhu zoster ubuhlungu uhlamvu kwenzeka kaningi ngemva kokuthatha eliningi -ukudla ezilwane. Ngaphezu kwalokho, isiguli emva kokudla kungenzeka ukhathazekile umuzwa njalo ukusinda esiswini. Zonke lezi zimpawu bashiya fast ngokwanele noma ukunciphisa namandla aso kule seziguli ezithola imithi aqukethe pancreatin. Phakathi kwabo, izidakamizwa ethandwa kakhulu ithole "Creon", "elithi mezim" futhi "Pancreatin". Uma uneminye ukuvuvukala kule izicubu amanyikwe kangcono futhi senqabe nhlobo kusukela ukusetshenziswa kotshwala. Iqiniso liwukuthi ngisho esincane kungaba babhebhethekise inqubo isifo, ngaleyo ndlela ulimaza kakhulu emzimbeni.