The best Isifaniso "cordarone" ngesiRashiya

Ukwelashwa nokuvikelwa inhliziyo isigqi iziyaluyalu - inkinga yezokwelapha eziyinkimbinkimbi ukuthi ingaxazululwa kuze kube sekupheleni, ngisho nanamuhla. Ziningi elwa ne-arrhythmic, kodwa Izimo eziningi side effects, ngoba lokho kungase kube yingozi kakhulu nesifo lesiguli. Kunamaqembu yonke izimali ezihlose ngempumuzo arrhythmias, ka kuphila kwetfu engotini, kodwa ukusetshenziswa kwabo isikhathi eside is hhayi Kunconywa ngenxa ukwanda okuholela emirarweni kokuthola imithi. Ngakho, iziguli ezidinga umuthi okuthembekile, esebenza kahle, kodwa ophephile, noma analog yalo.

"Kordaron" - isidakamizwa ngempumelelo antiarrhythmic

Ngokocwaningo olwenziwa ahlukahlukene, "Kordaron" Isidakamizwa ephumelela kunazo zonke ezinye imikhiqizo efanayo, has a ikhono efakazelwe ukuze kuncishiswe ukufa kwabantu iziguli isifo senhliziyo. Isetshenziselwa ngempumelelo ekwelapheni cishe yonke arrhythmias inhliziyo. Phakathi odokotela, yena kubhekwa lokuma for elwa ne-arrhythmic ekilasini III. Ngaphezu i antiarrhythmic, umphumela antianginal ke, kusukela ngowokuqala yasungulwa ngenxa izidakamizwa ekwelapheni isifo senhliziyo.

It has hhayi kuphela isici umphumela isigaba III antiarrhythmics, isb ukuvinjelwa iziteshi potassium, kodwa isinyathelo, isici ekilasini mina imikhiqizo, - nokuvinjelwa iziteshi sodium, ekilasini IV - ukuvinjelwa iziteshi calcium. Phakathi kwezinye izinto, lo izidakamizwa unika alpha- ne-beta-adrenoceptor Ukuvinjwa, yenhliziyo dilator umphumela.

izinkomba

Isithako asebenzayo zomuthi - amiodarone. igama Trade - "Cordarone." Analogs ezivezwa amanye amagama, kodwa aqukethe ketshezi asebenzayo efanayo. Amiodarone ikhiqizwa ngesimo isixazululo umjovo emthanjeni, kanye amaphilisi.

Isixazululo sisetshenziswa esimweni lapho kubalulekile ukuvimbela of ventricular futhi tachycardia supraventricular, fibrillation atrial, kubandakanya nokuquleka. Tablets asetshenziselwa nokuvimbela ventricular futhi arrhythmias atrial futhi paroxysmal tachycardia.

Umgomo we operation

Ngokucindezela nokusizakala inqubo yezokuthutha intracellular potassium ion, umuthi isikhathi eside Isigaba sesithathu we isinyathelo engaba ka senhliziyo esilimele amaseli. Iphinde suppresses ukudluliselwa ishayela kagesi kuleli Imicu yotshani engeyokuqala atrioventricular. Ngenxa yalokhu, i-pulse kubambezela. Ngenxa yalokho, i-ngokwengxenye Ukuvinjwa umphumela nonozwela isimiso sezinzwa siyehla ukushaya kwenhliziyo.

Amiodarone is akheka esibindini futhi excreted ikakhulukazi umchamo. Okuqukethwe esiphezulu we ketshezi esebenzayo waphawula ngemva kwamahora angu-3-7 ngemva ukungenisa tablet. Ngasekelwa nomphumela oqabulayo livela ngaphambili kuka iviki elilodwa ngemuva kokuqala ukwelashwa.

Analogs "cordarone"

Ezimweni eziningi, iziguli ngenxa yezizathu ezihlukahlukene uncamela izidakamizwa yasekuqaleni futhi okulinganayo yayo, imithi ejwayelekile. Njengoba "Kordaron" - nje egameni lendawo yokuhweba noma amiodarone, uhlushwa arrhythmias ngizibuze ukuthi kukhona izidakamizwa analogue "Cordarone."

Ngokuqondene amiodarone, umbuzo analogue yayo kuyinto efanele ngokukhethekile, ngoba ingenye izidakamizwa ethandwa kakhulu emhlabeni nezenhliziyo, has isicelo ebanzi. Le mithi, njengoba kushiwo ngenhla, kufanele kahle emzimbeni okungatheni, ngokuvamile ukuwohloka kwempilo. Ngakho-ke, udokotela kanye nesiguli unesithakazelo ukukhetha izidakamizwa ngempumelelo enkulu futhi ingozi okungenani ukuphila nezitho zomzimba. Uma ufuna okulingana izidakamizwa "Kordaron" kumakhophi, ukubuyekezwa lodokotela kulokhu kufanele ube i-ezibucayi, nakuba Yiqiniso, iziguli zangempela nayo ibalulekile, ngoba angakutshela ukuthi bazizwa kanjani ngesikhathi idili nesivinini ukuqala ngcono. Nale ukwelashwa "kordaron" noma yimiphi analogs kumele kuhambisane kweso lwezokwelapha kanye nokuqapha isimo sezempilo, kuhlanganise esebenzisa ECG.

Kufeza indima ebalulekile kanye nendlela okwakheke ngayo izidakamizwa. Ngokwesibonelo, i-iodine ingxenye amiodarone is contraindicated eziningi izifo. Futhi, angaphazamisa imiphumela ezinye izifundo. Akumangazi ukuthi abaningi ba- arrhythmia ngifuna Analogue "cordarone" ngaphandle iodine efana 'dronedarone. " Yiqiniso, indawo yayo yonke imithi kuphela emva kokubonisana udokotela wakho. Ngakho, izazi eziningi Russian musa batusa ukuba ukhethe "Dronedarone" ngokungadingekile, njengoba kuba ababuthakathaka analog "cordarone". Nokho, e-Europe, isivele ngempela kwandile.

Uma ukhetha izidakamizwa noma analog ezidingekayo ukuze uqhathanise Ukwakheka kwabo. Njengoba ojwayelekile, futhi okulinganayo ejwayelekile kungukuthi kuqhathaniswa nomunye - kuphela yasekuqaleni. Isibonelo, uma udinga i-analog "cordarone" e ampoules, endaweni yesixazululo okufanayo umjovo kufanele khona Gcoba i-Benzyl utshwala, njengoba yokuqala "Cordarone."

Njengoba odokotela cabanga, hhayi eliphansi kuya izakhiwo izidakamizwa "Kordaron" analogue eRussia ethulwa inombolo kahle esikhulu imikhiqizo, ezinye zazo yilezi: "Ritmiodaron", "Sedakoron", "Amiokordin", "Kardiodaron", "Ritmorest", "Opakorden" "Amiodarone" ezivela abakhiqizi ezahlukene ( 'Amiodarone-Acre "," Vero Amiodarone "kanye nabanye abaningi). Bonke babe isithako efanayo esebenzayo, kodwa kungase kudingeke excipients ezahlukene. Abaningi babo ishibhile kuka original. Ezimweni eziningi, lokhu isici kuncike umakhi. Ngokwesibonelo, "Amiodarone", okuyinto okuthiwa iyafana ketshezi eziyisisekelo eziqukethwe ukulungiselela "Kordaron". Analogue isiRashiya, futhi intengo yayo cishe ezintathu izikhathi ephansi, nakuba ukuma wokukhulula, kanye izinkomba ngenjongo efanayo.

"Amiodoron" - okungcono analogue eRussia. Kuyinto cishe izakhamuzi zaseBosnia zifana kusuka "cordarone" futhi isimiso isinyathelo, futhi indlela hlelo lokusebenza likwazi efanayo ukusebenza okusezingeni eliphezulu e ezobopha fibrillation iziqephu kanye nokuvimbela nesenzakalo yabo. Nobufakazi ngakho engxenyeni enkulu omuhle. Abaningi babo bathi "Amiodoron" ukukhiqizwa Russian kusiza ngokushesha futhi ngaphandle pobochki esindayo.

Nokushintsha kokudla nokufakwa umuthi e ampoules

Njengoba kushiwo ngenhla, ikhambi umjovo iboniswa impumuzo esheshayo yenkinga. isicelo "Kordaron" amaphilisi kwezinye izimo. Analogs isebenze ngendlela efanayo. I izixazululo abangu injected ngokusebenzisa ipayipi imizuzu 20-120 noma bolus okungenani amaminithi angu-3 ngesikhathi umthamo 5 mg ngayinye esisindo 1 kg.

Sokuphuzisa ithebhulethi "cordarone"

Umuthi esithathwayo iphilisi ngezigaba ezimbili.

Isigaba sokuqala, noma umthwalo isigaba: 600-800 mg kanye nsuku zonke, okwandisa-10 g.

Eyesibili step, noma nokugcinwa isigaba: 100-400 mg izidakamizwa (ubude kunqunywa udokotela). Umthamo esiphezulu 1200 mg ngosuku.

Ukweqisa izidakamizwa zomuthi kuyingozi ngokwanele. Ukuvimbela ke, isiguli Kunconywa ukuba wazi kahle indlela ukuthatha imithi "Kordaron" imfundo manual. Analogs, kuhlanganise uzakwabo ethandwa eRussia "Amiadaron", iningi labo ukunikeza izimpawu ezifanayo ukweqisa izidakamizwa.

Kukhona bradycardia oluqinile, ngisho kuze ukuboshwa inhliziyo. Uma kubangelwa ifomu ithebhulethi, kubalulekile ukuba iphume esiswini futhi uthathe chelators. Futhi aphethwe nokunye ukwelapha lingaze, electrolyte silinganisele kushintshwe. Uma kudingekile, cupha elingenalo iwashi lenhliziyo.

Mayelana emthanjeni Imininingwane ukweqisa izidakamizwa akuphelele. Kuchazwe Ezimweni ezingavamile ka itheku bradycardia, tachycardia, ukuboshwa inhliziyo. Ukwelashwa siyafana wabonisa for kokudla kubangelwa amaphilisi. Hemodialysis amiodarone futhi metabolites zalo akakhishwanga.

side effects

Njenganoma iyiphi indlela efanele isinyathelo esinamandla, "Kordaron" "Amiodarone" nezinye uchungechunge analogs avuse izigigaba ezingezinhle. Tibangela bradycardia kuze kube ukuboshwa inhliziyo, umfutho wegazi, ibe nomphumela ongemuhle kwesibindi, ngaleyo ndlela abe uhlu kunalokho umxhwele Izimo.

Kusukela ikhanda kancane ezinzima kodwa ezazibalulekile engemihle-Kungadala kuqashelwe nesiyezi, pleurisy, ukukhwehlela, isiguli ingase ikhononde lobuthakathaka, ukulahlekelwa acuity ezibukwayo. Bangase baxabane nomzimba. Inkinga efanayo ingatholakala ngokwenza noma yiziphi-analog. "Kordaron" namanye ama-tablet izidakamizwa amiodarone ngenxa yalesi sizathu, zidayiswa Pharmacy kuphela kadokotela. Isixazululo for umjovo isetshenziswa kuphela endaweni esibhedlela.

Nokho, ne zinakekelwe ekukhetheni esiphezulu umthamo side effects kuvetwa kancane noma zingase zingaveli nhlobo. Njengoba kuye kwaphawulwa Ukubukeza "kordaron" futhi "Amiodarone" iziguli ukuthatha le mithi, pobochka ngokuvamile ababuthakathaka, ukuqedwa kalula ngemikhiqizo ye ukulungiswa izidakamizwa umthamo.

Izimo

Njengoba amiodarone - umuthi namandla ngempela, akumangalisi ukuthi ngeke nje kusize isimo eziningi izinkinga inhliziyo, kodwa ngesikhathi esifanayo kokuba nethonya elilimaza kakhulu nezinye izitho noma isimo siba sibi izifo ezithile concomitant. Ukuze ugweme ingozi, hhayi Kunconywa yokwelapha nale izidakamizwa kwezinye izimo.

Kukhona uhla izimo okuyiwona banqatshelwe ngokwamukela "Kordaron", "Amiodarone" nezinye nozakwabo e ezibhebheni. Eyokuqala isimo senhliziyo ezinye normal - bradycardia itheku, atrioventricular block degree sina, hypotension, prolongation we qt kweminyaka ECG. It ayikwazi ukusetshenziswa uma isiguli lehliselwa okuqukethwe umzimba potassium ne-magnesium.

Izimo zihlanganisa abanale nkinga, kanye bekhulelwe nangenkathi bencelisa - isizathu iodine, equkethe lesi sidakamizwa "Cordarone." Analog, hhayi eyiqukethe, ingase ikhishwe kuphela iseluleko kadokotela.

Iziguli kwasebekhulile Kunconywa ukuthi ngokuqapha zithathwe ngokuthi "Kordaron" futhi "Amiodarone" nezinye analogs. Iziguli abaneminyaka engaphansi 18, lezi imithi akuzona abamiswe.

Musa nika indlela kulabo abaphethwe somoya bronchial, nokuvaleka kwemigudu yokuphefumula, uzwakalise yokumelwa yinhliziyo. Sinzima isifo sesibindi nezinso - futhi isizathu lokukwenqaba ngale ndlela.

Ngokungangabazeki, akufanele uthathe isidakamizwa uma kukhona ukungabekezeleli ngakunye izingxenye izidakamizwa "Cordarone." Analogue eRussia nakwamanye amazwe aseYurophu ube ukwakheka efanayo, ngakho kuleli cala esikhundleni nezinye ejenti eyodwa akunakwenzeka ukuba aphumelele.

Ngokuphathelene imijovo, abakwazi ukwenza izingane ezingaphansi kweminyaka engu-3 ubudala, izingane abaneminyaka engama 3, umthamo kumele singeqi 5 mg / kg. Musa mix izidakamizwa e-isipetu efanayo neminye imithi. Ngokuvamile, contraindications isixazululo afana contraindications amaphilisi. Lokhu bradycardia itheku, ogulayo itheku syndrome ne ezinzima conduction iziyaluyalu, njengoba sinoatrial block izinhliziyo futhi paroxysmal ventricular tachycardia. Ikakhulukazi, izenzakalo ezinjalo zingenzeka uma nithatha amiodarone lihambisana namanye izidakamizwa eziningana.

Batuse imijovo ngesikhathi sokukhulelwa kungenzeka kuphela Emacaleni angakajayeleki lapho lactation indlela yokwelashwa ayifakiwe ngokuphelele. Kuyinto engenakwenzeka ukuqhuba yokwelapha usebenzisa "cordarone" isixazululo nge yegilo ukungasebenzi, komzimba nezinto iodine noma amiodarone.

Ukuxhumana nezinye izidakamizwa

"Kordaron" zingahlanganiswa nezinye izidakamizwa. Ngakho, umphumela walo antianginal luphakanyiswa lihambisana nitrate izidakamizwa nokunwetshiwe senzo. Ingasetshenziselwa ngokuhlanganyela anticoagulants, isisu, izidakamizwa cardiotonic, musa basebentisane nalabanye nekukhuluma, ngokulandelana, ungalulazi noma ukuqinisa umphumela ngamunye "Kordaron" futhi abanye neuroleptics nezinye, analgesics, hypnotics futhi sedatives. Cishe njengoba isabela mithi iyiphi analog.

"Kordaron" ayikwazi ukusetshenziswa kanye kanye mao inhibitor ne-beta-blocker (ezimweni ezehlukile kuphela).

Okumele kuqashelwe ekwelapheni "kordaron" futhi "Amiodarone"

Ngesikhathi yokwamukela lezi izindlela sidinga ukuba isimo umzimba ukuqapha ngaphambi kokwelashwa, ngesikhathi nangemva kwalo.

Ngaphambi naphakathi ukwelashwa ithebhulethi ifomu ukubambelela ECG Kunconywa. Effect zomuthi kubangela izinguquko electrocardiogram, ngokukhethekile, prolongation we isikhawu T ne-Q-Q-T. Ukulandela imiphumela, udokotela angase ulungise umthamo kanye ukunquma ukuphumelela ukwelashwa.

Ukwelashwa inqanyulwa lapho asathuthuka block atrioventricular II no III degree sinoatrialnaya, intraventricular ezimbili uvumelanise.

Njengoba omunye izingxenye umuthi iodine, kudinga ukuqapha njalo imisebenzi yegilo. Ngaphambi ukwelashwa kuyadingeka ukunquma izinga lama-hormone i-T3, T4 futhi TSH. Sicela uqaphele ukuthi ku isizinda "cordarone" yendlala radioisotope izifundo kungaba alithembekile. On amazinga ama-hormone iodine akuphazamisi idatha.

Esinye isici esibalulekile ukuba kutholakale izinga potassium serum igazi ngaphambi ukwelashwa kanye phakathi kwalo.

Lapho sinikezwa "cordarone" Kunconywa ukumnika emthanjeni kuphela, hhayi umjovo isipetu. Uma kungenjalo, mhlawumbe ukuthuthukiswa izifo hemodynamic - hypotension lwemithambo, acute esingamahlalakhona senhliziyo. Isipetu ukujova izidakamizwa kuphela ezimweni ezehlukile eziphuthumayo ngokungabi bikho okunye okungenziwa. Kulokhu umthamo 5 mg / kg futhi itholakala imizuzu emithathu, kabusha - kungekho ngokushesha kunezinsuku angu-15 ngemva ekuphathweni kuqala. Inqubo kungaba kwenziwe kuphela yenhliziyo neminyango ukunakekelwa ngaphansi kokuqondisa ECG. "Kordaron" ngeke ngephutha isipetu nezinye izidakamizwa. Uma une ekwelashweni eside liyadingeka ukuya ukumnika. Noma yimuphi amiodarone emthanjeni kwenziwe izibhedlela.

Uma isiguli uzoba izinzwa jikelele, izinzwa kufanele baziswe ukuthi kokuthatha lesi imithi.

Ukuze ugweme side effects, iziguli kufanele athobele Isikali ebekiwe udokotela.

Phakathi ukwelashwa, iziguli kufanele ugweme elangeni bese usebenzisa Ukuvikelwa ngokumelene nalo (kuhlanganise okhilimu ekhethekile), uma kunesidingo.

Qiniseka ukukhuluma nodokotela wakho, uma ngenxa yesizathu esithile ungafuni ukuthatha "Kordaron" futhi okuphikisana nalo. "Kordaron" nezidakamizwa efanayo naye, nje njenganoma yiluphi olunye izidakamizwa inhliziyo ingaba yingozi kakhulu uma reception engalawuliwe. udokotela kuphela ungakwazi ukunquma ukuthi iyiphi imithi kungaba kuhle kakhulu uma wakho futhi ukhethe sokunamathela esilinganisweni esiphephile, kodwa eziphumelelayo.