Pseudomyxoma peritoneum: Izimbangela, Izimpawu, Sifo Nokuselapha

Pseudomyxoma peritoneum kuyinto zokugula okungukuthi nobuntu ekuqongeleleni isikhwehlela, ekugcineni othola kabusha.

Kusho ukuthini?

Igama livele ososayensi ukuba Werth ngo-1884. Ekuqaleni isetshenziswa amacala izilonda yesibili, izinhlumba sokucasuka ukuphumelela. Ngokuhamba kwesikhathi, sathola ukuthi pseudomyxoma peritoneum kubangela ukufuduka ngaphakathi komgodi izinto ezitholakala esithasiselweni, okuyinto yena, wenza ukugeleza urinary ukuphumelela noma nenyongo.

Ososayensi bathole ukuthi kwenqubo yokwakhiwa kwamakoloni isikhwehlela kungenxa amakhefu nokuguqulwa lapho ngokweqile ukuzelula kancane noma ukunciphisa nodonga lwawo ukujiya, kanye kokungenela kuhlinzwa: ekususeni nginesimila noma isithasiselo saleli Bhayibheli.

Futhi ngaphansi ngesibonakhulu?

Lapho eseyinsizwa efundela ezomthetho ingaphakathi ngesikhathi kokukhulisa okusezingeni eliphezulu ke kuyabonakala ukuthi pseudomyxoma peritoneum egcwele izidakamizwa serous yokuqala, kulo angenele isikhwehlela. Lokhu kubangela ukuvuvukala, ngenxa okuyinto ezindongeni ukusonteka kwenzeka:

• ukuqina;
• amanzi;
• imibimbi.

Kwezinye izimo, ebusweni iba velvet-like, kuyilapho kwezinye izindawo kukhona ukopha. Lapho ukuthuthukiswa zokugula kwenzeka nokunamathisela ngomthofu izihibe emathunjini, omentum nasesiswini. Ngemizimba ulahlekelwe ezidingekile ukusebenza evamile ukuhamba.

Ukutadisha endaweni ethintekile ngesibonakhulu, ungabona ukuthi amaseli lapho isikhwehlela has a ungqimba Indwangu, ingxenye lapho kukhona kokuziphatha. Epithelium kulezi cells Ushintshe kungaba:

• cubic;
• isicaba.

Ukwakheka ekugcineni amaseli isifo abathintekayo uyashintsha, it is kunqunywa nesigaba lesi sifo. Lapho sitholakele "pseudomyxoma peritoneum" kumaseli isikhwehlela avele:

• lymphocyte;
• fibroblasts;
• multi-core yamaRefa;
• leukocyte polymorphic;
• histiocytes;
• epithelium columnar.

Indlela yokugcina ingenisa kuleli peritoneum. It lingena emzimbeni ke ngokusebenzisa perforation. Kuyinto ngenxa lesi senzo sokukhwabanisa epithelium, futhi kwahlanganiswa isigaba neoplastic izifo pseudomyxoma peritoneum, ogama izimpawu ngokuvamile esobala. Inqubo ukuqhutshwa sluggishly, kusekelwa isikhwehlela, ubhekwa ukuvuvukala.

Isimila - kungcono scary?

Izimila secrete peritoneum ezimbili zama:

• oyinhloko;
• lesibili.

Of imithi ebulalayo kaningi elungisa ke metastatic, okungukuthi yesibili. Ngokuqondene eyinhloko ke kubo fanele peritoneum pseudomyxoma. Izimpawu zesifo okokuqala, it ongabonakali. With ukuthuthukiswa kwezifo amaseli kwenzeka phezu peritoneal ngaphandle kokuphazamisa izitho eduze. Lena isici esiyinhloko salo umdlavuza kuchazwe. Indlela amaseli esiphelweni itheleleke - ehlasela umzimba.

Kuleso simo, ngaphandle uma le ndlala bayamangala nezinye indwangu, uthi kutholakale ukuthi une pseudomyxoma peritoneum, okuyinto umhlahlo okungekuhle. Lokhu ikakhulukazi kungenxa yokuthi ukuthi zokugula ngokuvamile zitholiwe zangokwasemuva zezinhlelo umdlavuza kakade ngaphambilini ebonwe nezinye izitho.

ukuhlola

Sifo "pseudomyxoma peritoneum" ngokuvamile sibeke at laparotomy. Yabela ke lezi zimpawu ezilandelayo:

• ubuhlungu besisu (ngokuvamile zibuthuntu);
• ukunyusa ivolumu isisu ngaphandle kwesizathu.

Lokhu kwenzeka ngenxa sokuzuza izicubu uketshezi lomzimba.

avelele:

• umonakalo elinganiselwe;
• psevdomiksoglobulez.

Kwenzeka kanjani lokhu?

Ngokuvamile, isifo kubonakala ukudabuka isizinda simila. Lokhu kungenxa yokuthi intuthuko is Ukungena ku ngalo ingaphakathi lesisu, hhayi kuphela slime, kodwa futhi we epithelium. amaseli yakhe unekhono esiyingqayizivele itshalwe nezicubu lapho bezithola. Ngokuhamba kwesikhathi, amasayithi ngamahlumela ezinga eliphansi omunye futhi uqale esikhiqiza isikhwehlela.

Ngokuvamile, sitholakele "pseudomyxoma peritoneum" kusho ukuthi lesi sifo ebulalayo. Pathology basonta ebusweni, akuvezi kuwukwephula ukusebenza kwezitho zangaphakathi kanye nezinhlelo. Pseudomyxoma ephathekayo, it libhekene "shaking syndrome." Namuhla, indlela kuphela ephumelelayo ekuxilongeni isifo - ukuhlinzwa lapho amasampula izicubu etholwe. zokugula isiqinisekiso kuhlinzekwe yinkampani biopsy.

Okufanele ukulindele?

Kufanele ube ukulungele ukuqinisekisa ukuthi uphethwe "pseudomyxoma peritoneum" impatho - ukuhlinzwa. Enye indlela ngempumelelo zokunqanda zokugula okwamanje yasungulwa wayengekho. Uma isimila kungavamile ukuba ingozi, ke kuyodingeka usike, unikezwa lapho izicubu namanje enempilo.

Lapho isifo ukonakala ukuthola kuphela amathuba abulalayo lokuphulukiswa, abazimisele ukuya sokususwa olukhulu. Onalesi sifo okungekuhle. yokutakula Okugcwele kungenziwa olulindeleke kuwuphawu lwesimila ingozi yenqubo, kodwa ngemva kokuzalwa ngisho nokuhlinzwa akakwazi ivimbele ngokuphelele izinqubo zokukhiqiza kanye ukunqwabelana slime.

Odokotela akuzona njalo ukwazi ukunquma ngokunembile ukuthi kwase umdlavuza. Lokhu kwembulwa cwaningo histological, okungase ukhombise ukungabi khona amangqamuzana omdlavuza e nezicubu isampula elathathwa, kodwa awukwazi ukukhonza njengesiqinisekiso sokuthi emzimbeni kukhona nhlobo.

Lapho uphethwe ukwelashwa "pseudomyxoma peritoneum" kukhethiwe, zikwenze uzitshele ukuthi isimila isivele umdlavuza. Lokhu kungenxa imvamisa eliphezulu uyahluleka uma elwa nokuphuza, ekuhlaselweni.

Yini okumelwe uyenze?

Ngaphambi uqonde ukuthi sisho ukuthini isifo "pseudomyxoma peritoneum" (esigabeni sokugcina) izimpawu zezifo, udinga kuqala ukucacisa, ukwelashwa ngemisebe namakhemikhali yabonisa ngokudonsa izinyawo ekulweni nezifo.

Okwamanje samanje, hhayi yasungulwa yisimangaliso lesi sifo. Vele ekususeni isikhwehlela yabonisa ingaphelele ngoba amangqamuzana ngesinyenyela epithelium, ziyaqhubeka zithela ke.

Kukholakala ukuthi imiphumela emihle ingatholakala radiotherapy, uma kukhona yokuchayeka izicubu abathintekayo platinum, isotopes igolide.

Ngaphandle ukuphathwa efanele umuntu onesifo uyafa esikhathini esingangonyaka noma emibili. Kwezinye izimo, lesi sifo kuhambisana fistula esikhumbeni.

ezicashile ezibaluleke

Izibalo zithi pseudomyxoma peritoneum kwenzeka cishe 1% eziguli, Ngakho-ke, it is labizwa ngokuthi ezingavamile kakhulu. ingozi yaso notshwala ezifihliwe, ukuthuthukiswa atypical, futhi Izibikezelo abampofu.

Kwezinye izimo, ukuthuthukiswa zokugula kwenzeka ngokumelene mucin appendicular. Phakathi izimpawu ngasocansini of Oncology - wamathumbu isimiso.

Lesi sifo libhekene lezi zinhlobo ezilandelayo mucin:

• Mahhala.
• Imali. Ukwabela ezinkulu, ezincane. Ziyakwazi kufanelekile kuhle Friend kwamanzi peritoneal. Imali zenzeka izinqubo ukuvuvukala futhi amaseli samanje mesothelial. Kwezinye izimo, zikhona fibroblasts, ama-capillary. Kodwa amaseli non-plastic ezimweni eziningi ayikwazi ukutholwa.
• Pools. Lezi uquqaba ngokuvamile njengoba izicubu igobolondo kollagenizovannuyu. Kwezemfundo isayensi, ezifana yehlukanise mucin.

Ubani okumelwe ubakholelwe?

Eminyakeni yamuva, izibhedlela eziningana Israeli ukuqinisekisa ikhambi eliphelele umdlavuza. Ngokuvamile, izinhlangano ezinjalo ungayeki zethembiso olusemthethweni, kodwa ukwenza izikhangiso esimnandi, nokunika ithemba iziguli kanye nezihlobo zabo.

Khumbula ukuthi udinga ukukhetha nezikhungo zezokwelapha, ngaphambili kokuthi uzifunde ngokucophelela imibhalo, kanye izimpendulo zalabo empeleni waya khona ukwelashwa. Qaphela odokotela abonakele futhi inkonzo abampofu.