"Polioksidoniy" ingane: ukubuyekezwa, yokusetshenziswa, ukwakheka kanye nencazelo

Ingaziki futhi agule ngesikhathi sonyaka imikhuhlane imikhuhlane - lena umsebenzi oyinhloko abaningi bethu. olufanele Ikakhulukazi kuba mbuzo uma kuziwa ezinganeni. Lapha kubalulekile ukuba sifune ezihlukahlukene izidakamizwa ezingaba ukuqinisa amasosha omzimba futhi ukwandisa ukumelana lomzimba isifo. Kulesi simo, abazali abaningi abakhetha "Polioksidoniy 'ngoba umntwana, ukubuyekezwa ukusho ukuthi emva isicelo yayo akuvamile izingane bayagula futhi baqala njalo ukuya enkulisa. Kuvame ebekiwe immunologists, odokotela, kodwa ngemva ahlolwe kahle emzimbeni wengane.

isidakamizwa

"Polioksidoniy 'ngoba umntwana (impendulo omama banake iqiniso lokuthi izidakamizwa Kufanele umise oyisazi kuphela ngemva kokutadisha immunogram) evame ukunikezwa ngesimo suppositories, futhi impuphu isixazululo. Izingane kusukela ngineminyaka engu-nambili ungadla amaphilisi.

Omunye sibhebhe sinamaphutha 12 mg azoximer bromide. Nezinsizasenzo amaphilisi kuphuma stearic acid, monohydrate lactose futhi amazambane isitashi.

I lyophilisate ngokubhala slurry ehlanganisa esebenzayo isithako azoximer bromide. Ikhishwa ngezilinganiso 3 mg kanye 6 mg. izithako engeziwe kukhona betakaroten, mannitol futhi povidone.

Lwesitho sangasese sowesifazane kanye suppositories rectal aqukethe azoximer bromide at umthamo 6 mg kanye mg 12. Ngesisekelo izenzo cocoa ibhotela e isamba 1.3 g suppository ngayinye. izinto yesibili nazi izingxenye efanayo powder isixazululo.

Khipha ifomu kanye nencazelo

"Polioksidoniy 'ngoba umntwana (lobuya abanye omama bathi akuyona njalo ngempumelelo, futhi izingane ukuba iqhubeke ibonisa ogulayo emva kokudla njengenjwayelo) has ukukhululwa ifomu elandelayo:

• amaphilisi;
• suppositories kwezokuphatha rectal futhi lwesitho sangasese sowesifazane;
• powder for umjovo kanye intranasal isicelo.

Umuthi amaphilisi etholakala ibhamuza 10 namayunithi 20. Dragees ezinemibala ngombala omhlophe kanye yellow. Basengozini, chamfer futhi eliqoshwe umbhalo othi "IN". On ezindaweni zawo ezincane impregnation inhomogeneous kungabonakala nasemkhakheni.

Lyophilisate isixazululo yokukhiqiza akhiqizwa ampules kanye glass amabhodlela ngezilinganiso 4.5 futhi 9 mg. Engqamuzaneni ngalinye kukhona nentaba of ampoules ezinhlanu noma izitsha eziyisikhombisa. Zonke ebhokisini amakhadibhodi 50 izitsha eziyisikhombisa (izitsha eziyisikhombisa). Lokhu emaphaketheni ephawulwe "izibhedlela". Lo muthi hygroscopic kanye nokuzwelana ukukhanya.

Suppositories abe ukuma torpedo futhi ababethi ophuzi. Uma ukusetshenziswa yabo okungase kuthintwe avulekile ukunambitheka cocoa. I intshabusuku wabo izingcezu ezinhlanu. Iphakheji ezimbili ibhamuza.

pharmacodynamics

"Polioksidoniy 'ngoba umntwana (Izibuyekezo bathi izidakamizwa kusiza Yiqiniso lesi sifo nge obstructive nesifo samaphaphu), odokotela belulekwa ukuba uthathe uhlelo ababuthakathaka mzimba, njengoba iyi-ejenti immunostimulatory, futhi kwandisa ukumelana zezingane emiphumeleni izifo zendawo generalized.

Umuthi liyithinta ngokuqondile ku amaseli phagocytic futhi natural killer cells. Akhuthaza ukwakheka esiningi kwamasosha omzimba. In izifo immunodeficiency okuphindaphindiwe ubuyisela umsebenzi zokuzivikela. Lokhu ukuchayeka izidakamizwa kwenzeka uma izifo zibangelwa ukuhlukumezeka, izifo eziningi, izinqubo sokuhlasela kwamasosha omzimba, ukusha, izimila ebulalayo kanye nesimo esinzima nasezinkingeni ezilandela ngemva kokuhlinzwa. Futhi, izidakamizwa elibekelwe iziguli abasebenzisa amahomoni steroid, ama-ejenti chemotherapeutic namanxusa cytotoxic.

Ngaphandle izakhiwo immunomodulatory, "Polioksidoniy" libhekene detoxifying futhi izakhiwo antioxidant. Lokhu kuwukhulula umzimba ubuthi futhi elisindayo zensimbi. Kuvimbela namachibi ukusabela. Ngenxa imiphumela enjalo emzimbeni izidakamizwa isetshenziswa ekwelapheni umdlavuza iziguli ngempumelelo. Kulokhu, kunciphisa ubuthi ngamakhemikhali nemisebe yokwelapha, esiza ukugwema emibi lezi izinqubo.

Isabelo "polioksidoniya" ngesikhathi immunodeficiency kwaso ngokuphindaphindiwe kwandisa ukuphumelela ukwelashwa zokwelapha kanye kunciphisa ubude bayo. It kwandisa ukuthethelelwa ezinye izifo sifushanise nokusetshenziswa kwamaphilisi, bronchodilators futhi corticosteroids.

Umuthi has tolerability ezinhle, mitogen, has umsebenzi polyclonal antigenic futhi sanikwa izimfanelo. Ayikho imiphumela emibi emzimbeni.

Izinkomba ngoba ukusetshenziswa "Polioksidoniy" kusho

Ukubuyekezwa izingane (intengo izidakamizwa ayizinkulungwane emhlabeni) bathi izidakamizwa kwandisa imisebenzi okuvikela umzimba futhi ingane ngemuva kokuthi kusetshenzisiwe ogulayo ingasaphathwa.

Izinsana izidakamizwa engabelwe bakteriovirusnyh nezifo fungal esigabeni oyingozi futhi ezingalapheki. Kunconywe ukusetshenziswa ngezigaba okunzima komzimba kanye ubuthi anobuthi zomzimba. Inhloso somoya bronchial, kuyinkimbinkimbi engenhla zokuphefumula izifo ipheshana. izidakamizwa ezinqunyelwe atopic dermatitis kuvuze ubomvu foci, dysbacteriosis nokuhlunyeleliswa okusheshayo izifo ezingaphezu eside. Isetshenziselwa njengoba isilinganiso izifo ukuze kuvikelwe Umkhuhlane ne-SARS.

Tablets "Polioksidoniy": yokusetshenziswa

Inani (izibuyekezo izingane kungukuthi belulekwa ukuba linqume izidakamizwa bebodwa, ngaphandle kokukhuluma nodokotela, ngoba enamandla kakhulu izidakamizwa mzimba-inkanuko, okuyinto bengayiqondi ngokugcwele) ngoba abanye omama siphakeme ngokwanele futhi ngenxa yalokho akubona bonke abakwaziyo ukuthenga ke.

Amaphilisi eyenziwa ngezindlela ezimbili: temlomo na sublingual. Iphilisi idliwe kuze kuphele isigamu sehora ngaphambi ukudla main. Kubantu abadala, umthamo nsuku zonke 24 mg ngelanga, nezingane kusukela iqembu engu-nambili akufanele baphuze angaphezu kuka-12 ml ngosuku. Umuthi ezinqunyiwe ukuze izikhathi 3 ngosuku.

Sublingual izidakamizwa engabelwe izifo ezihlukahlukene emlonyeni pharynx. esiphezulu I umthamo wansuku zonke is 24 mg, ihlukaniswe yaba nezigaba ezimbili, ngayinye yaba kuxazululwa ngu 12 mg. Isikhawu phakathi nesimiso sokuqondisa izidakamizwa kufanele kube okungenani amahora angu-12. Le nqubo yokwelapha ithatha izinsuku ezingaba ngu-14.

Uma isifo esibangelwa izifo of HSV temlomo na fungal ngokwemvelo futhi wathutha ifomu ezinzima, ukulungiswa Kunconywa ukuba kuthathe 12 mg kathathu ngosuku. Isikhawu phakathi yokwamukela amaphilisi kuyinto amahora ayisishiyagalombili.

Ngo sinusitis chronic otitis zisebenzisa esinye isibhebhe sibonisa kabili ngosuku. Ubude besikhathi 5-10 izinsuku.

Lapho ezingamahlalakhona namathansela ifomu kufanele aphelise iphilisi elilodwa kathathu ngosuku, ngokugcina isikhawu phakathi yokwamukela imithi ilingana amahora ayisishiyagalombili. Ubude yokwelashwa amasonto amabili.

Okungalapheki bronchopulmonary isifo umthamo iphathwa of 24 mg, ukuze zidliwe izinyathelo ezimbili. Inkambo ihlala kufika emavikini amabili.

Ngokuba nokuvimbela Umkhuhlane futhi sibi zokuphefumula igciwane lohlobo, uma isiguli ehlupheka izikhathi ezingaphezu kuka ezine ngonyaka, umuthi isetshenziswa kabili ngosuku. Le nqubo yokwelapha ithatha izinsuku ezingaba ngu-15.

ekuphathweni Oral Izibhebhe wabonisa ekwelapheni engenhla ipheshana zokuphefumula. Lapha izinga omdala 24 mg (amaphilisi amabili), izingane kusukela 12 - 12 mg. Inkambo amasonto amabili.

sokuphuzisa amakhandlela

"Polioksidoniy" ngokuvamile Kunconywa nokuvimbela imikhuhlane ingane suppositories ukusetshenziswa rectal. Imiyalelo (amakhandlela izingane Izibuyekezo belulekwa ukuba ufake ngokuqapha, njengoba abavunyelwe ukusebenzisa iminyaka 6 kuphela ubudala, futhi lapho kusetshenziswe isencane, bahlukene zibe izingxenye ezimbili) ngaphambi ukusetshenziswa kwezidakamizwa incoma ukuthi bonana nodokotela wakho kuqala.

Umuthi kule fomu lisetshenziswa uma ebusuku, kodwa esimweni ngasinye sihlukile futhi isikhathi lokulawula ukwelashwa onguchwepheshe. Umuthi ingasetshenziswa nsuku zonke, futhi kamuva ngosuku, ezimbili.

Isikali ihlukaniswe izigaba ezimbili, lesi sidakamizwa "Polioksidoniy":

• Amakhandlela 6 mg izingane (libuyekeza ezinye iziguli bathi kancane kunokuphakela imijovo) aqokwa eneminyaka engu-eminyakeni eyisithupha.
• Suppositories 12 mg, kuboniswa ukuthuthukisa ukuntula mzimba kwabadala.

Uma ikhandlela asetshenziswa rectally, ngaphambi ukubethula emzimbeni ayinalutho nhlobo wamathumbu. izidakamizwa Intravaginal isetshenziswa kanye ebusuku.

Ngokusho ezivamile uhlelo suppositories, kungakhathaliseki ngomthamo, zisebenzisa kanye ngosuku, izinsuku ezintathu. Esikhathini esizayo, amakhandlela esetshenziswa ngosuku. Aphatha exchange kuhlanganisa amakhandlela 10-20. Uma kudingekile, ukuphinda ukwelashwa emva ezintathu kwezine.

Iziguli immunodeficiency okungamahlalakhona, ukwelashwa immunosuppressive, Oncology, futhi abantu abanegciwane lesandulela-ngculaza ngemva kokuzibeka elangeni ukusebenzisa izidakamizwa kumele kube eside, ezinyangeni ezintathu ziye ngonyaka. Kukhona imibukiso abengeziwe yokwelapha ekwelapheni futhi basekelane. Kulokhu, lo suppositories iphathwa izikhathi 1-2 ngesonto.

Imiyalelo ukusetshenziswa powder

Yabela "Polioksidoniy" impumulo izingane (Izibuyekezo bathi kuyinto ithuluzi esiphelele nokuvimbela imikhuhlane kanye nemfuluwenza) e adenoids nezinye izifo ngalo ingaphakathi ngomlomo. Umuthi ingasatshenziswa parenterally futhi sublingually izingane. Umzila yokuphathwa futhi umthamo kumelwe ukhethe udokotela.

Ukuze ukusetshenziswa esicutshini futhi emthanjeni, "Polioksidoniy" okunqunyiwe izingane, kusukela ngineminyaka engu-izinyanga ezintathu nsuku zonke, njalo ngemva kosuku noma kabili izinsuku eziyisikhombisa ngesikhathi 100-150 mg / kg. Odinga ukukwenza 5-10 nezinqubo.

Lapho i-ejenti ukuvuvukala watusa iqondiswa Njalo ngemva kosuku olulodwa umthamo esingeqile 100 mg / kg. Ubude besikhathi sokwelashwa -7 izinsuku.

Ngo yizifo ezingamahlalakhona, kuba ezihilela izinqubo ukuvuvukala, umuthi isetshenziswa-150 UG / kg, kabili ezinsukwini ezingu-7. Inkambo - imijovo eziyishumi.

Uma kukhona isifo ifomu iguliswa noma enobuthi-iguliswa acute, umuthi isetshenziswa ngemithambo yegazi (ukuvuza) kuya ku-15 mg / kg lihambisana namanye amanxusa anti-iguliswa.

Lapho ezinzima yokungezwani komzimba izidakamizwa iqondiswa intramuscularly ngesikhathi umthamo 100 mg / kg. Break phakathi imijovo kuba izinsuku 1-2, inkambo - 5 nezinqubo.

Ukulungisa liquid esicutshini umjovo isitsha noma ingilazi ibhodlela 3 mg ziyoncibilika 1 ml amanzi umjovo, okuyinto ungayithola enye by 0.9% isixazululo sodium chloride uma kudingeka.

Ukuze emthanjeni umjovo isitsha noma isitsha ingilazi at 3 mg buhlanjululwe sodium 1.5-2 ml 0.9% chloride.

Intranasal nokusetshenziswa sublingual

lingasetshenziswa hhayi kuphela umjovo, kodwa futhi intranasally, ejenti sublingually immunomodulatory "polioksidony". Ikhala lehla izingane (izinkomba bathi abaphathi enjalo zomuthi kancane kunokuphakela umjovo, kepha omnene, ikakhulu njengokuba imijovo ibuhlungu kakhulu) ngokujwayelekile 150 mg / kg isetshenziselwa 5-10 izinsuku, isb 1-3 amathonsi yanjalo kuya ikhala kwesokunxele nakwesokudla noma sublingually njalo ngemuva kwamahora amathathu.

Drops "Polioksidoniy" izingane (Izibuyekezo bathi ukuvimbela kahle ukuqala izifo ezibangelwa amagciwane kanye esithathelanayo) iqondiswa e ikhala ngalinye 1-3 amathonsi. Inqubo iyaphindwa njalo emahoreni 2-3.

Ngo ezinhlanu amakhilogramu isisindo kumelwe bawe amathonsi ezinhlanu zomuthi ngosuku, okungukuthi 0.25 ml isixazululo. Lapho ingane ukala 10 kg, waye uDavide esenza okusesikweni amathonsi eziyishumi noma 0.5 ml izidakamizwa. Ngakho, ukuze uthole isisindo 15 kg kumelwe bawe amathonsi nanhlanu noma 0.75 ml we lyophilizate kanye isisindo emzimbeni 20 kg Kunconywa ukuba asebenzise amathonsi amabili noma 1 ml ukulungiswa.

Ukukhiqiza isixazululo 3 mg powder u buhlanjululwe in 1 ml amanzi distilled. Ingasetshenziselwa ukulungiselela umkhiqizo nqabela-omisiwe "Polioksidoniy" amanzi ngokuvamile abilisiwe. Omunye Iconsi nomuthi equkethwe mayelana 150 UG bromide azoximer. okuhlushwa wayo ibalwa okusekelwe isisindo umzimba wengane.

Isixazululo lokugcina ubekwe kwisiqandisi ngeviki. Ngaphambi kokusebenzisa i-pipette necebo sishisiswe lokushisa + 20-25 ° C.

Izimo futhi side effects

Umuthi akakubangeli engemihle. Ngezinye izikhathi, ngemva umjovo kungaba buhlungu kancane umjovo ku imisipha.

Umuthi akufanele isetshenziswe ngesikhathi sokukhulelwa futhi ukuncelisa ingane. Banned sokusebenzisa ukungabekezelelani ngakunye izingxenye lichaza ekwakheni amafa futhi sidala kangakanani ingane sikhatsi lesingaba tinyanga letisitfupha.

Qaphela ikakhulukazi uma usebenzisa izidakamizwa in iziguli ukwehluleka oyingozi kwezinso kubantfwana labancane kunalabo izinyanga 6.

imiyalelo Special

Weluleka ne ubuhlungu imisipha emva umjovo ukulungiselela isixazululo 25% procaine powder "polioksidony" Umsebenzisi Isicelo, izibuyekezo izingane batusa izidakamizwa iqondiswa emzimbeni by ngokuqinile ebekwe udokotela, uma isiguli akuyona iguliswa procaine.

Lapho iqondiswa ngemithambo yegazi, ukulungiswa umjovo akuyona ezifuywa e amaprotheni-equkethe ukumnika izixazululo.

izindleko

"Polioksidoniy" ithengiswe kuphela Pharmacy bese abadedela kuphela kadokotela. Inani, kuye ngesimo ukukhululwa zomuthi zingahluka. Ngakho, ukulungiselela isixazululo mg 3 powder kubiza ruble mayelana 650 izitsha eziyisikhombisa ezinhlanu, futhi 6 mg imali kuyodingeka bakhokhe ruble mayelana 1,050. Inani lwesitho sangasese sowesifazane kanye rectal suppository umthamo 6 mg ruble angu-800, futhi ezingu-12 mg amakhandlela kuyodingeka bakhokhe ruble 950. Izindleko isembozo amaphilisi zibe izicucu eziyishumi kuyinto 750 ruble.

Izibuyekezo

Ngokuvamile engabelwe imikhuhlane isikhathi eside izifo ezingathi sína kwababhemayo "izingane Polioksidoniy ', libuyekeza odokotela bathi ke iyithuluzi elibalulekile ekwelapheni izifo eziningana ezithathelwanayo. Umuthi akakubangeli imiphumela emibi futhi kalula ikubekezelele iziguli. Isimiso ukwelashwa nesineke ngayinye ifaniswe.

Amakhandlela Bheka "Polioksidoniy" izingane ezingaphansi konyaka (izibuyekezo uthi imiphumela yayo omuhle emzimbeni futhi wazi isikhathi ukuncishiswa izifo kanti ukuthatha izidakamizwa) belulekwa ukuba ufake ngokuqapha.

Abazali abaningi bangase baphikise ngokuthi izidakamizwa kuthuthukisa isimiso somzimba sokuzivikela, kunciphisa isikhathi zokugula. Lo mbhalo uthi ephumelela kunazo kukhona imijovo, nakuba ibuhlungu kakhulu, futhi akubona bonke abantwana bayakwazi ukumelana nabo. Nakani iqiniso lokuthi lokhu izidakamizwa ezinamandla futhi kumele liqoke immunologist udokotela ngemva kokutadisha immunogram. Abazali belulekwa ukuba uphuthume uyowuthenga futhi batusa lwahlolwa ukuze kuvelana izidakamizwa.

imicabango yabantu Negative mayelana izidakamizwa uyifune ayinayo imiphumela emihle emzimbeni futhi placebo. Ukugubha izindleko zalo okusezingeni eliphezulu kanye nokuntuleka ucwaningo. Bathi kungaba yingozi umntwana ezifweni futhi evimbela kumiswa imisebenzi yemvelo zokuzivikela.