"Motonium": yokusetshenziswa, ngempela

Ngaphansi ukuhlanza ziyabonisa futhi kuqhuma (reflex) okuqukethwe isisu ngomlomo. Ngokuvamile, lezo zinqubo landulelwa nesicanucanu ngephutha ukugwinya uhlamvu, uketshezi ethuthukisiwe wezinyembezi ngamathe futhi ukuphefumula okusheshayo.

Bekanye Izinsalela ukudla, juice esiswini, isikhwehlela, Bile nezinye ukungcola, indoda ejaculates kanye nezakhi. Kungabangela amanzi emzimbeni futhi electrolyte ukungalingani. Ngakho-ke, lapho ukuhlanza eqinile futhi njalo, qiniseka ukuthatha isibalo izinyathelo uyakukusindisa zonke amaminerali nezinye izakhi zomzimba womuntu.

Omunye antiemetics ethandwa kakhulu kuba "Motonium". Yokusetshenziswa, izakhiwo zangempela kanye contraindications of the izidakamizwa tibalwe lapha ngentasi.

Ukwakheka izidakamizwa, ezakheke, emabhokisini kanye nencazelo

Ngayiphi ifomu idedela izidakamizwa "Motonium"? Umhlahlandlela ibika ukuthi lo mkhiqizo ekhiqizwa ngesimo round kanye amaphilisi ezimhlophe ifilimu-camera. isithako wabo asebenzayo uba domperidone. Futhi kufakwe nomuthi: I-lactose, microcrystalline cellulose, glycerol, corn isitashi, magnesium stearate futhi ongaphakeme yamangqamuzana isisindo povidone. Ngokuphathelene ukuvundulula ulwelwesi, ukuthi liqukethe hydroxypropylmethylcellulose kanye polyethylene glycol 6000.

Thenga amaphilisi "Motonium" (ngawo amiswa, sizokutshela ngezansi) kungaba amabhamuza noma amathini plastic, awafaka amakhadibhodi amabhokisi.

Isenzo zomuthi

izidakamizwa "Motonium" Isebenza kanjani? Imiyalelo isicelo ibonisa ukuthi kuyindlela ukwandisa isikhathi of Kufinyeta peristaltic ku duodenum futhi antrum isisu. Ngaphezu kwalokho, it kakhulu ngesivinini bethulula esiswini (ngesikhathi deceleration yenqubo), aqede umuzwa isicanucanu nokuhlanza, kanye ngomphimbo sphincter ithoni inyuka (engezansi).

Yini enye engingabuye izidakamizwa emangalisayo "Motonium"? Izibuyekezo abonisa ukuthi ikhuthaza ukukhululwa kwe prolactin kusukela indlala pituitary. Effect Its anti-emetic kubangelwa ithonya neuropathy noma gastrokinetic futhi bengathandwa ka Dopamine receptor ise zone chemoreceptor inhlamvu.

Kufanele futhi wazi ukuthi domperidone akunamthelela le uketshezi of juice esiswini.

izici kinetic

Kuyini sici kinetics zomuthi ngokuthi "Motonium"? Yokusetshenziswa okufunwayo ngemuva kokuthatha izidakamizwa, yena ugxile kunalokho ngokushesha.

Lesi sidakamizwa has bioavailability ongaphakeme (cishe 15%). igazi lokuhlala wayo isiqongo waphawula ngemva kwemizuzu engu-60.

Encishisiwe esiswini asidi juice kwehlisa inqubo ukumuncwa domperidone. Akazange zingene kusivimbeli gazi ebuchosheni, futhi ngenxa yalokho ukusetshenziswa kwalo kakhulu kuyaqabukela ephelezelwa engemihle.

I nomuthi "Motonium", yokusetshenziswa oboniswe ngezansi, is kahle basakaza emisipheni. Nokho, emakamu yayo ebuchosheni azinakwa. Sesibopho ukuthobisa plasma amaprotheni lokulungiselela 91-92%.

Amade akheka esibindini echayeke izidakamizwa futhi izindonga emathunjini. isikhathi sayo isigamu-ukuphila amahora 9, futhi ukwehluleka kwezinso (uzwakalise) esikhathini elilandelayo yinde.

Kuboniswa imithi izinso futhi ngokusebenzisa namathumbu.

Izinkomba ukuthola amaphilisi okwelapha

Kwezinye izimo, ukulungiswa nesineke "Motonium" angabelwa? Uphenyo odokotela baye bame kwelokuthi lokhu imithi isetshenziswa eyinkimbinkimbi izimpawu dyspeptic elihlobene ne Reflux esiswini noma ngomphimbo, esiswini ukukhululwa okuqhubekayo noma esophagitis. Ngakho, lapho i-ejenti kuncike isetshenziswa ukubuyisa, lokujabulela ukuphelela e epigastrium, lokujabulela ukuvuvukala, ukubhodla, ubuhlungu esiswini engenhla, futhi isilungulela ngaphandle ekubunjweni (noma, Ngakolunye uhlangothi, nge Reflux) lokuqukethwe esiswini emuva emlonyeni.

Kusukela yini enye kusiza izidakamizwa "Motonium"? Yokusetshenziswa libike ukuthi lokhu ukulungiselela aqede umuzwa isicanucanu, ukuhlanza, kuvimbela ukuthuthukiswa imvelo organic, ezithathelwanayo, futhi ukusebenza, kanye kubangelwa radiotherapy, Ukudla sifo, imithi kanye yokwamukela Dopamine agonists (isb, "Bromocriptine" noma "Levodopa").

Izimo ukuthola izimali

Lesi sidakamizwa ngokuqapha Kunconywa ukuthatha abantu esingamahlalakhona hepatic noma kwezinso. Ngaphezu kwalokho, akukashicilelwa ngesisu noma ukopha emathunjini, hypersensitivity, wamathumbu perforation, noma esiswini, mechanical isimiso emathunjini, kanye khona prolactinoma futhi ongaphansi kweminyaka engu-iminyaka emihlanu.

Izidakamizwa "Motonium": yokusetshenziswa

Thatha izimali kufanele kube ngaphakathi imizuzu 20-35 ngaphambi kokudla. Umthamo zomuthi kuncike isimo lesiguli.

Ngo ezingamahlalakhona dyspepsia izingane eminyakeni emihlanu nomuthi iqondiswa kg esisindo 2.5 mg / 10 kathathu ngosuku. Ezimweni eziphuthumayo isidakamizwa esithathwayo futhi ngaphambi sokulala. Njengoba abantu abadala, bona uzoqoka 10 mg zomuthi (ie 1 tablet) kathathu ngosuku, futhi uma kudingeka - nje ngaphambi sokulala.

Uma kudingeka, umthamo ecacisiwe zingandiswa kabili.

Ngo oyingozi futhi subacute uthi (nesicanucanu nokuhlanza) iziguli omdala iqondiswa mg 20 ka nomuthi (isb amaphilisi 2) kane ngosuku, futhi ngaphambi sokulala. Izingane kusukela koneminyaka eyisihlanu leli thuluzi Kunconywa ukuthatha 5 mg / 10 kg esisindo kathathu ngosuku futhi ngesikhathi sokulala.

side effects

Kubhekwe antiemetic ayivamile ukubangela ukusabela ezingezinhle. Kukhona amacala lezivakashi amajaqamba emathunjini, futhi iziyaluyalu extrapyramidal e izingane kanye nabantu permeability okwandisiwe Bbb.

Ngaphezu kwalokho, e seziguli ezithola lokhu izidakamizwa angagcina komzimba ezifana urticaria futhi ukuqubuka. Ngezinye izikhathi izidakamizwa esebenzayo kubangela hyperprolactinemia (gynecomastia futhi galactorrhea).

Overdose kwezidakamizwa

Yiziphi izimpawu zenzeka uma nithatha ebulilini izimali? Izazi zithi lokhu izidakamizwa kungabangela ukozela, disorientation nezimpendulo extrapyramidal, ikakhulukazi ezinganeni.

Ukuze ekwelapheni izimo ezinjalo isisulu isebenze wamalahle ikhiphe antihistamine. Lapho antiparkinsonian futhi anticholinergics kungenziwa okuvela extrapyramidal ukusabela nesineke Kunconywa.

Ukuxhumana nezinye izindlela

imithi Anticholinergic iwukudambisa umphumela domperidone.

Sodium Bicarbonate, "cimetidine" nezinye protivosekretornye futhi antacids ukunciphisa bioavailability zomuthi.

Imithi elwa namagciwane okuqondene iqembu macrolides, izidakamizwa antifungal azole, "Nefazodone" futhi-HIV protease inhibitor domperidone ukwandisa lokuhlushwa igazi.

Ukusetshenziswa kwabesifazane abakhulelwe kanye lactating

Izidakamizwa "Motonium" kungenziwa iphathwe senyanga yokuqala sokukhulelwa, kodwa kuphela izinkomba ekhethekile.

I domperidone ubisi lwebele lokuhlala kane ngaphansana plasma. Ochwepheshe angazi umphumela domperidone ongathandeki eziningi kangaka esikhathini izinsana. Ngakho-ke, ibele kufanele kwayekwa lapho ethola amaphilisi.

izincomo ezithile

Abantu ne ezinzima esingamahlalakhona kwezinso, izidakamizwa isigamu-ukuphila kunyuke kusuka 9:00 kuya 20. Nokho, lokuhlushwa izidakamizwa egazini ephansi kakhulu kunalokho abantu enempilo.

Ngenxa yokuthi lokhu izidakamizwa excreted ngu izinso ngesilinganiso esincane, ukulungiswa yayo iyunithi umthamo in iziguli ukungakhuli kwezinso ayidingekile. imithi umthamo Nokho okuphindaphindayo kaningi yayo kufanele ibe ngu- kabili ngosuku (kuncike degree of ukwehluleka).

ekuphathweni Okungalapheki imithi, iziguli kufanele ibe ngaphansi ebhekiwe.

isikhathi Isitoreji nemibandela yeziboshwa

imithi Okubukwe kufanele igcinwe endaweni eyomile, bavikeleke ukukhanya kanye kufinyelela khona izingane ezincane. lokushisa Isitoreji akumele kube ngaphezulu kuka-degree 25.

Impilo eshalofini zomuthi izinyanga 24. Musa baphuze amaphilisi emva kokuphela kwesikhathi esibekiwe iphakethe.

Izidakamizwa "Motonium": Izibuyekezo nesineke

Mayelana ukucabangela kusho kukhona Izibuyekezo eziningi kangaka. Ngokuvamile, zingabantu esihle. Abathengi bathi lokhu umuthi ngempela ngempumelelo ekunciphiseni ukuhlanza futhi aqede umuzwa isicanucanu. Ngaphezu kwalokho, izidakamizwa esebenzayo ivame banciphise izimpawu eziwumphumela wokugula dyspeptic.

Ngaphezu ukusebenza high, uquketheni lokhu izidakamizwa ahlanganisa ukuntula kwayo Izimo sina nokutholakala. Kufanele kuqashelwe ukuthi le izidakamizwa "Motonium" cishe zamenza imiphumela emibi, kuhlanganise ezinganeni abaneminyaka engama 5 ubudala.