KLF - siyini lesi sibalo futhi siyini ukubusa kwawo?

Ukuze sitholakele udokotela ngokuvamile limisa ezihlukahlukene izivivinyo ezisiza ukuthola lesi sifo. Ukuhlola wadalula igazi, umchamo, isikhwehlela, noma eminye imikhiqizo imfucuza yomuntu.

ukuhlaziywa kwamakhemikhali kwegazi

Ukuhlolwa kwegazi wenziwa cishe zonke izifo, ngenxa kwanoma yiluphi ushintsho yokwakheka igazi kungase lula ukuxilongwa. Chitha, ngisho noma isiguli alibonisi impilo yakhe asikhali ngalutho. Lokho sika kungani, uma ngempela ukunakekelwa ngawe, oxhumana naye udokotela ukuze ngezikhathi zithunyelwe wena kulolu cwaningo. Lokhu kuyiqiniso ikakhulukazi labo abakwaziyo ukufunda ezinye izinkinga inhliziyo, isibindi kanye nezinso.

Kuyini UFC?

KLF - kuyini? Ukuhlaziywa CK wumkhakha wezindleko igazi ukuhlaziywa kwamakhemikhali kanye yokunquma inani creatine phosphokinase. Le nto ngokuvamile egcinwe kwamanye imisipha, ikakhulukazi imisipha lwamathambo kanye inhliziyo.

kinase Creatine kuyinto ikhemikhali ukhiqiza ATP kusukela creatine futhi enye into okuthiwa phosphocreatine. Le ngxube edliwe ngezinye umsebenzi ephakeme ngokomzimba zomzimba. Ngaphezu imisipha yohlaka kanye isibindi kumaseli zobuchopho, wamaphaphu yegilo.

Lapho kufundwa CK ukuvelela iwe?

Uma umonakalo lamaseli CPK imisipha Imicu yotshani ishiya, futhi okuhlushwa yayo egazini luyanda kakhulu. Yingakho ukuhlolwa laboratory ukuze kutholakale izinga CPK egazini zinokwethenjelwa ukuba ngaphakathi mayelana 100%. Bavumela wena ukuxilonga isilethikusebenza. Ekupheleni amahora 2-4 lapho kuqala ukuhlaziya ukukhombisa ukuthi CPK anda, kodwa le nkomba ngokushesha ayibhampise emuva.

Ngaphezu kwalokho, kukhuphuke CPK kungabuye amqaphela angokoqobo imisipha, ukuchotshozwa yabo futhi isifo, kanye ngemuva kokusebenzisa imali enkulu utshwala nokuhlukumeza amaphilisi elele.

Ukuncishiswa le nkomba okungukuthi hhayi waphawula endaweni yokucwaninga cwaningo.

Izici ukuhlaziywa

CPK ukuhlaziywa - ukuthi kuyini nokuthi inqubo wenziwa? Ukuze ukuhlole salokhu ipharamitha isetshenziswa indlela evamile. He is kanje: kusukela umthambo we ibhodi lemisindo (ie, kusukela enkulungwaneni yesithathu engenhla ibhodi lemisindo) Uchwepheshe kwenza kocingo ethile yegazi. Ngemva kwalokho, sithathe igazi ithunyelwa laboratory, lapho ucwaningo olwenziwe.

Ngaphambi ngokwedlulele noma yiluphi ucwaningo isiguli akuyona efiselekayo. Ngakho, umphumela kuyoba ngaphezulu ulwazi futhi kunembile.

Ukuze kutholakale izinga CPK kwegazi Kwenziwa photometry. Ihlala ku yamangqamuzana absorbitsionnom Spectral cwaningo. Amathekhiniki kufakwe lolucwaningo, esekelwe ukumuncwa emisebeni kagesi, okuyinto eyenzeka ngo-inqubo yokhetho. I absorbance ezivezwa molecule ingxenye, okuyinto ezingeni iyenziwa ezindaweni ebonakalayo, infrared kanye ultraviolet bohlu. Futhi, compounds ezingase zimuncwe nge CK reagent.

Ukuze isifundo umshini ekhethekile - CK-photocolorimeter.

Izinkomba kanye nemiphumela

Ziyakwazi ubufakazi ukuhlaziywa:

• ekuhlonzweni ka isilethikusebenza (kuyadingeka ukuze uhlaziye elandelayo amahora 2-4);
• Ukwahlukaniswa sitholakele isifo senhliziyo uma lokhu kuhlasela okungukuthi elihlangene ne lula noma kube lula ukuhlaselwa angina.

Ngaphezu kwalokho, lokhu ukuhlaziywa inikezwe zonke iziguli abelashwayo yanoma yimuphi isifo senhliziyo, ukukhipha iqiniso ngemuva kokuhlaselwa yisifo senhliziyo. Kuyinto ulwazi ezingeni CPK (okungukuthi, ngenhla) kuzokusiza ochwepheshe ukucacisa isimo senhliziyo. Ukwanda yalolu ketshezi egazini kungase kubonise kungenzeka unezinkinga zenhliziyo. Uma lesi simo sibangelwa bemvelo unomphela, udokotela ezimweni eziningi enza isinqumo ekwelashweni zokuvimbela ukuthi uzoyeka ukuqhubeka kwesifo esikhathini esizayo.

CPK igazi (okungukuthi, kungatholakala ekuqaleni isihloko) luyanda kulezi zimo ezilandelayo:

• isilethikusebenza (inani lenyuka uxilongwe e amahora okuqala angu-2-4, esiphezulu kufinyelelwe nosuku; ukubaluleka kuyehla, kodwa akukho ukuzinza emva kwezinsuku 3-6);
• sokuwohloka kwemisipha;
• Reye Syndrome (acute hepatic encephalopathy) ;
• ukushaqeka;
• ubuthi ahlukahlukene, ikakhulukazi, utshwala kanye amaphilisi elele;
• izifo we myocardium.

Encishisiwe igazi CK (okuyinto echazwe ngenhla) siyenzeka nokungawuvivinyi ngokwanele yemisipha, yokuphila umzimba, futhi ikhonza njengombonisi inkomba ongaqondile-hyperthyroidism (ukudakwa hormone egilo engeziwe, okuyinto akhiqizwa indlala yegilo).

CK amazinga. kuyinsakavukela

Ukuze ngokwanele ukuhlola ubuhlobo okuhlushwa umsebenzi ingqikithi CK isetshenziswa ibalwa Inkomba isihlobo. ifomula sayo simi ngale ndlela:

RI (Inkomba ibalwa) = CK-MB (UG / L) / ingqikithi. CK (U / L) * 100

Inkomba ibalwa ngamaphesenti.

CK-rate uwukubonakaliswa amanani alandelayo:

• <24 IU / l -KFK-MB;
• <6% yomsebenzi Imininingwane CK;
• Laboratory kuyinsakavukela - 10-110 IU;
• SI amayunithi - 0.60 - 66 mmol / l.

Ulwazi oluphathelene namagugu inkomba (kwezinkambiso) lezi izinkomba, futhi kufakwe ukuhlaziywa izinkomba laboratories ezahlukene zingahluka. Nokho, umehluko phakathi amazinga azinakwa, futhi lesi sifo sitholakale umuntu noma kunjalo.

Indlela sokulungiselela umnikelo wegazi ngoba ukuhlaziya CK?

Ukuze imiphumela awazange zamanga-HIV igazi Kunconywa ukuba azithathe elingenalutho esiswini. Ivunyelwe ukuphuza amanzi ahlanzekile ngaphandle amanyela. Ngemva kokudla ngaphambi kokunikeza igazi ukuze kutholakale izinga CPK (lokho kuchazwa ngokuningiliziwe ngenhla) kufanele agcwalise ubuncane 8 amahora, futhi kulapho, ngcono. Uma uthatha noma iyiphi imithi ukuthi akulungile ukuthatha ukuhlolwa. Lokhu kumele kwenziwe ngaphambi kokuba uqale ukuphuza imithi, noma amasonto amabili ngemuva. Uma uyeka ukuphuza imithi noma ngayiphi indlela abakwazi ke uchwepheshe kumele icacise zonke izidakamizwa ukuthi njengamanje ehlelekile kuthathwe yisiguli, kanye umthamo wabo.

Elinye iphuzu elibalulekile ukuthi ufuna cabanga ngaphambi ngegazi - ezemidlalo. Ngaphambi ngqo ukulethwa yokuhlaziya akukhuthazwa, hhayi kuphela ukwenza asebenzayo umsebenzi, kodwa futhi ukuba nakho ocindezelayo isimo futhi isiphuzo utshwala, ngisho nasezintweni ezincane kakhulu ezintweni ezikhipha. Ngaphezu kwalokho, musa ukuthatha isikhathi ukuba unikele ngegazi ukuze kutholakale izinga CPK ngokushesha emva x-reyi,-X-ray luhlolo (ngisho wathatha isithombe izinyo noma umunwe), nezinqubo ultrasound, ezihlukahlukene ukuze athole ukwelashwa komzimba noma luhlolo rectal.

Yikuphi kungathinta ezingeni CPK?

Kunezindlela eziningana izici ezingase zithinte imiphumela yocwaningo wegazi CPK futhi kuholele ukuhlanekezela:

• umsebenzi okuphezulu ngokomzimba;
• ethola amalungiselelo yezokwelapha ngemithambo yegazi;
• Hilez isampula;
• ethola inombolo yemithi;
• hemolysis.

Amazinga aphakeme creatine kinase, okuyinto kunqunywa ukuhlolwa laboratory, zingase zibe Indlela izinguquko emzimbeni okuhlotshaniswa isilethikusebenza, rabdomiliozom, sokuwohloka kwemisipha, miotizom, umsebenzi ngokweqile, futhi ukuhlinza yinkimbinkimbi nelula.

Uma Nokho, ukwehla ezingeni le nkomba, khona-ke akukho zokuxilonga value, awusebenzi.