Isidakamizwa "i-Ursosan": imiyalo yokusetshenziswa

Isidakamizwa esithi "i-Ursosan" sikhululwa ngendlela yama-capsules, ngalinye equkethe 250 mg we-ursodeoxycholic acid esebenzayo. Isidakamizwa sifakiwe emkhakheni wezokwelapha kanye nezokwelapha we-hepatoprotectors, ene-choleretic, isenzo se-gallstone-dissolving.

I-ursodeoxycholic acid ibuye ibekwe njenge-agent efaka imithi nge-lipid-lowering, hypocholesterolemic kanye nomunye umphumela wokuzivikela nge-immunomodulating.

Isidakamizwa esithi "i-Ursosan", imfundo yokusetshenziswa ibonisa, inezakhiwo ze-polar, okwenza kube nokwenzeka ukwakha ama-micelles angenayo into enobuthi. Ngakho-ke, kungenzeka ukunciphisa ikhono le-reflux yesisu sokubhubhisa izingqamuzana zamangqamuzana ezinjenge-gastritis ye- peptic , i- peptic esophagitis. I-ursodeoxycholic acid ingakha ama-molecule amabili ayingxenye yezingqamuzana zamangqamuzana anjenge-hepatocytes, ama-cholangiocytes, i-GIT epitheliocytes, ivuselela imisebenzi yawo, futhi ikhulise imishanguzo yamakhamera ase-cytotoxic.

Ukusetshenziswa kwezidakamizwa "i-Ursosan" kunganciphisa izinga le- bile acids eliyingozi elilimaza i-hepatocytes, livuselela i-choleresis, lithonya isinqumo esiphephile se-cholestasis ye-intrahepatic, sinciphise inkinga ye-lithogenic ye-bile. Ngakho-ke, izidakamizwa "i-Ursosan", imfundo yokusetshenziswa ibonisa, isetshenziselwa ukuqothula ama-gallstones afakwe ku-cholesterol, ukuvimbela ukufakwa kwezimboni ezintsha emidayeni ye-bile.

Umphumela we-immunomodulating utholakala ngenxa yokuvimbela umsebenzi wezinhlobo ezithile ze-antigens, ukujwayelekile komsebenzi wokubulala we-lymphocytes. Kuye kwasungulwa ukuthi i-ursodeoxycholic acid inqanda ukuthuthukiswa kwezinqubo ze-fibrotic kulezi ziguli ezixilongwe nge-cirrhosis eyinhloko, i-alcoholic steatohepatitis, i-cystic fibrosis.

Isidakamizwa "i-Ursosan", isicelo

Isidakamizwa sinqunywe:

• Nge-cholelithiasis, eqhubeka ngaphandle kwezinkinga;
• Lapho ukuchithwa kwama-gallstones okwakhiwa kusuka ku-cholesterol ku-gallbladder;
• Ukuze kuvikelwe ukuphindaphinda kokubalwa kokubala emva kwe-cholecystectomy;
• I- hepatitis engapheli ifomu elisebenzayo;
• With hepatitis acute;
• Ukulimala kwesibindi sobuthi;
• Nge-cholangitis eyinhloko;
• Ngezifo zesibindi ezihlobene nokudakwa ngokweqile;
• Ngemvelaphi engezona utshwala;
• Nge-cirrhosis eyinhloko yohlobo lwe-biliary;
• I-cystic fibrosis yesibindi ;
• Nge-gastritis ye-peptic ne-esophagitis;
• Nge-syndrome ye-biliary dyspeptic;
• Ukuze kuvikelwe izifo zesibindi ezihlobene nokusetshenziswa kwezizalo zokuvimbela imithi ye-hormonal noma i-cytostatics.

Umthamo wesidakamizwa ukhethwe udokotela kuye ngokuthi uhlolwe yini nesimo sesiguli.

Isidakamizwa "i-Ursosan", imiyalo yokusetshenziswa, nemiphumela emibi

Ukuphazanyiswa emgomweni wokugaya kubonakaliswa yizinyosi, ukuhlanza, isifo sohudo, ukuqothulwa, ukuphakama kokuhamba kwesikhathi kwe-transaminase ye-hepatic; Esikhathini sokuhlolwa kwemitholampilo, ukubunjwa kwamacilstones ahlanganisiwe kwaqashelwa.

Okunye ukuphazamiseka emzimbeni kungabonakala njengokubuyiselwa emuva, ukusabela okwenziwe okwehliswayo, ukukhushulwa kwe-psoriasis engapheli, i-alopecia.

"Imithi ye-Ursosan", imiyalo yokusetshenziswa, ukuphikisana

Musa ukuphatha lesi sidakamizwa kulezi zimo ezilandelayo:

• Ngama-gallstones, aqukethe i-calcium eningi;
• Nge-fistula ye-bile-esiswini;
• Nge-cholecystitis ngesimo esibucayi;
• Nge-insufficiency ye-hepatic;
• With cholangitis acute;
• Nge-cirrhosis yesibindi;
• Ngokwehluleka kobuqili;
• Ngokuvinjelwa kwama-bile amadokodo;
• Ngezifo ezithathelwanayo eziyingozi ezitholakala kwi-gallbladder;
• Ngesibindi se-gallbladder ;
• Ngokuzwela okwedlulele kumuthi.

Lapho echaza ukuthi izidakamizwa ziyoncibilikisa izigulane, udokotela kumele acabange ukuthi lezi zimali kufanele zibe nomsuka wokudla, hhayi ngaphezu kwe-15-20 mm ngobukhulu. Kulesi simo, i-gallbladder kufanele isebenze, ihlale ingenasipiliyoni engaphezulu kwama-50%, ukuze i-patency igcinwe.