I-Lornoxicam: imiyalo yokusetshenziswa, ukubuyekezwa, ukufana

Izifo ezihambisana nobuhlungu nokuvuvukala, akunakuqhathaniswa njengento engekho emtholampilo wanamuhla. Ngokwemvelo, kunezinkulungwane zemithi ehlukene yokulwa nokuvuvukala kanye nokuzibulala engakwazi ukuyiqeda. Omunye wabo umuthi "Lornoxicam". Imiyalo yokusetshenziswa kulokhu ilula kakhulu, futhi odokotela bavame batusa leli thuluzi. Kodwa yimuphi umuthi? Ungayisebenzisa kanjani ngokufanele? Zikhona yini izinkinga? Le mibuzo ibuzwa iziguli eziningi.

Ukwakhiwa kanye nesimo semithi

Lesi sidakamizwa sitholakala emafomu amabili: amaphilisi kanye ne-powder yokulungiselela amajojo.

Ekhemisi ungathenga amaphilisi amancane ahambisanayo ngegobolondo elilukhuni lombala omhlophe, ngezinye izikhathi umbala ophuzi. Into esemqoka esebenzayo yi-lornoxicam. Isidakamizwa singase sibe nesilinganiso esithile se-4 noma 8 mg yesithako esisebenzayo. Enye ibhansela iqukethe amaphilisi angu-10, futhi kuphakheji kunamabhansela angu-1 noma amathathu. Njengamakhemisi asizayo, izinto ezifana ne-talc, i-lactose, i-hydromellose, i- titanium dioxide, i-stearate ye-magnesium, i-polyvidone K25 ne-croscarmellose sodium zikhona lapha.

Kukhona i-lyophilizate yokulungiselela imijovo, okungukuthi isisindo esinobuthi obuphuzi, esibekwe ebhodleleni le-glass hermetic. Into esebenzayo ibuye i-lornoxicam (isilinganiso - 8 mg). Njengemisebenzi eyisizayo, i-disodidium eyedidium, kanye ne-mannitol E-421 kanye ne-trometamol zikhona lapha.

Izakhiwo ezinkulu zemithi

Lesi sidakamizwa yisidakamizwa esingezona-steroidal sokulwa nokuvuvukala, esesigaba sezinkinobho. Into esebenzayo yalesi sidakamizwa igxilile umsebenzi we-COX-2 isoenzyme, okwenza futhi ihambe kancane kancane kwe-prostaglandin. Ngakho-ke, lesi sidakamizwa sinciphisa ukuthuthukiswa kwenqubo yokuvuvukala.

Ngaphezu kwalokho, le-agent ivimbela ukukhululwa kwama-oxygen radicals mahhala kusuka ku-leukocyte esebenzayo. Isidakamizwa sinemiphumela emihle ye-analgesic.

Pharmacodynamics yokulungiselela

Amathebulethi "i-Lornoxicam" afakwe kahle emthonjeni wesisu, ngemuva kokuthi angene egazini, lapho cishe cishe amaphesenti angu-99 aphethwe amaprotheni e-plasma. Ngendlela, uma uthatha isidakamizwa ukudla, khona-ke ukuhlushwa okuphezulu egazini kwehla ngo-30%. Ukutholakala kwezidakamizwa yi-99-100%. I-half-life is short and is four hours.

Izinqubo zokusungula umzimba kwezidakamizwa ezisebenzayo zikhona ezithombeni zesibindi. Isidakamizwa asikwenzi ukufakwa kwe-enzyme yesibindi. Ama-metabolites adunyiswa emathunjini nasezinso (cishe 30% weqhaza).

Izinkomba eziyinhloko zokusetshenziswa

Empeleni, izidakamizwa zisetshenziselwa ukususa cishe noma yiluphi uhlobo lobuhlungu. Isibonelo, kuba ngumngane obalulekile kubantu abane-arthritis, okubandakanya izifo ezithathelwanayo, i-rheumatoid, amafomu ama-gouty acwebile kanye nama-psoriatic wesifo. Ngaphezu kwalokho, lesi sidakamizwa sisusa ngokuphumelelayo ukuvuvukala nokudabuka kwe-ischialgia, ukubola kwe-osteoarthritis, i-osteochondrosis, kanye ne-radicular syndrome.

Amathebulethi nawo anqunyelwe ukukhulula ubuhlungu bezinyosi, ukuya esikhathini nesisindo somzimba. Ama-injection asetshenziselwa kakhulu emithini yokwelapha ukuqeda ubuhlungu obuhamba ngemva kokuthungatha nokuthutha.

Amaphilisi e-Lornoxicam: imiyalo yokusetshenziswa

Uma kukhona ukuvuvukala nobuhlungu, kuyaphuthuma ukubona udokotela. Akukhuthazwa ukusebenzisa noma yikuphi izidakamizwa ngokwezombusazwe, njengokuhlolwa kwezokwelapha okudingekayo ekuqaleni. Udokotela oya khona kuphela ongakhipha amaphilisi "Lornoxicam". Imiyalo yokusetshenziswa iqukethe izincomo ezijwayelekile kuphela futhi ihloselwe kuphela ukubhekisela.

Ngokuvamile, odokotela batusa ukuthatha i-tablet eyodwa kabili noma kathathu ngosuku (kuye ngokuthi okuqukethwe komuthi osebenzayo). Isilinganiso esiphezulu esingavumelekile singama-16 mg wezinto ezisebenzayo. Ubude benkambo yokwelashwa kunqunywa udokotela. Nakuba lesi sidakamizwa asivamile ukubuthelwa emzimbeni, ukwelashwa kwesikhathi eside kudinga ukuqapha okuqhubekayo, ikakhulukazi, ukuqinisekiswa kwegazi lesiphambano, izinga lokuvala, njll.

Isidakamizwa esithi "Lornoxicam": imiyalelo yokusetshenziswa, imijovo

Uma udokotela ekunikeze izijovo, okokuqala udinga ukulungisa isisombululo. Ukuze wenze lokhu, udinga ukuqoqa u-2 ml wamanzi ahlanzekile ukuze uthole imishanguzo ibe yindilinga ehlanzekile bese uyifaka emgqonyeni usebenzisa inaliti. Zisuse kahle kuze kufike isisombululo esifanayo. Ngemuva kwalokho, thatha umuthi ngesirinji esisha, shintsha inaliti. Umjovo kufanele wenziwe ngokushesha emva kokulungiswa kwesisombululo.

Isidakamizwa singasetshenziswa kokubili nge-intramuscularly futhi ngaphakathi. Kwezinye izimo, umjovo ungaba ubuhlungu, kodwa lokhu kungagwenywa. Uma ufaka izidakamizwa ngaphakathi kwemisipha, ubude benkambiso kufanele budlule imizuzwana emihlanu. Emthonjeni, umthamo owodwa wesidakamizwa kufanele unikezwe imizuzwana engu-15.

Isilinganiso kulokhu, futhi, sinquma udokotela. Njengomthetho, u-8 mg wezinto ezisebenzayo (okuqukethwe kwe-vial eyodwa) unikezwa isiguli kanyekanye. Njengoba ubuhlungu obukhulu, inqubo ingabuyekezwa futhi. Kodwa kubalulekile ukukhumbula ukuthi umthamo omkhulu wansuku zonke u-16 mg lornoxicam, futhi uyadlula kakhulu.

Kwezinye izimo, iziguli zidinga ukuhlolwa okungeziwe. Isibonelo, phambi kwesifo somfutho wegazi ophezulu wobunzima obuthakathaka noma obulinganisayo, kubaluleke kakhulu ukuqapha ukucindezelwa komzimba kulo lonke ukwelashwa. Iziguli ezinokukhubazeka ngokweqile kufanele ziqondiswe njalo abasebenzi bezokwelapha futhi zihlolwe njalo ngezinso zezinso.

Ingabe kukhona ukuphikisana kokwelapha?

Ingabe zonke izigaba zeziguli zingasebenzisa lesi sidakamizwa "Lornoxicam"? Imfundo yokusetshenziswa ibonisa ukuthi kunezinkomba zokwelapha, nakuba zingekho eziningi zazo:

1. Okokuqala kuyadingeka ukuthi uqaphele ukuxilonga kwezinto eziyingxenye - kulawo maguli ingozi yokuthuthukiswa kokuphendula okwenyukayo yanda.
2. Lesi sidakamizwa sinemikhawulo ethile yobudala - ayikwazi ukuthathwa yizingane kanye nentsha engaphansi kweminyaka engu-18 ubudala, kanye nabantu asebekhulile.
3. Ukuqhathaniswa kokufaka phakathi kufaka phakathi izikhathi zokukhulelwa kanye nokwaziswa.
4. Umuthi awukwazi ukuthathwa ngezifo ezithile zegciwane lokugaya, kuhlanganise nezilonda ezincelisayo, ukuvuvukala kwamathumbu, ukuphuma kwegazi.
5. Ukuhlukunyezwa kwesibindi nezinso nakho kunomkhawulo kulolu hlobo lwezokwelapha.
6. Phakathi kwamanye ama-contraindications kufaka phakathi izinhlobo ezinzima zomshuwalense, ukuhluleka kwenhliziyo ngokukhululeka, kanye ne-leukopenia kanye ne-prostaglandin asthma infhma.

Ukusabela okunzima okungenzeka

Ngokushesha kufanele kuqaphele ukuthi lesi sidakamizwa esithi "Lornoxicam" asivamile ukudala izinkinga. Ngakolunye uhlangothi, ukuqeda ngokuphelele amathuba okubukeka kwabo akunakwenzeka, ngakho-ke kufanele ujwayele uhlu lwemiphumela emibi:

1. Ngokuvamile, umuthi usebenza ohlelweni lokugaya ukudla. Ezinye izikhalazo zesiphithiphithi esiphendukayo, kanye nobuhlungu besisu, ukuhlanza, nezifo zesibindi. Ngokuvamile kancane kunomile emlonyeni, flatulence. Phakathi kokusabela okungavamile kunazo zonke kubandakanya ukuhlukunyezwa kwesibindi, ukuphuma kwamathumbu emathumbu, ukubunjwa kwezilonda zamapulprit, isisu somzimba kanye nesifo somzimba.
2. Ngesinye isikhathi ukubonakala kwemizwa evuthayo, okuvame ukuhambisana nokuhlukunyezwa kwesikhumba, imifantu, ukuvuza, ukubomvu, ukuvuvukala, nokunye okungavamile - i-dyspnoea nokunyuka kwenhliziyo.
3. Mhlawumbe umphumela wesidakamizwa ohlelweni lwezinzwa, olubonakaliswa emakhanda ekhanda ngezikhathi ezithile, isizungu, ukukhushulwa okukhulu, ukuphazamiseka kokulala.
4. Ngezinye izikhathi, umuthi uphazamisa umzimba, ohambisana nokuguqulwa kwesisindo somzimba, ukukhukhumezeka okukhulu, ukukhukhumeza.
5. Kwezinye izimo, ushintsho ohlelweni lwe-clotting lwegazi lugcinwa ngokumelene nesizinda semithi yokwelapha, okuhambisana ne-hemorrhoidal hemorrhages.

Ukudlula ngokweqile, izimpawu zalo kanye nokwelapha

Iziguli eziningi zinentshisekelo ngemibuzo mayelana nokuthi kungenzeka yini ukudlula izidakamizwa "Lornoxicam". Imfundo ibonisa ukuthi amacala anjalo ahlonishwa, kodwa ngokweqile kakhulu futhi, njengoba umthetho, ahlobene nokukhubazeka okungahambi kahle kwesiguli noma ukulawulwa okungalawulwa kwemithi.

Izimpawu zokuqala zokudlula ngokweqile kuyi-nausea nokuhlanza. Kamuva, ezinye izibonakaliso ze-cerebral zingabonakala, kufaka phakathi isiyezi esinamandla kanye ne-ataxia. Ezimweni ezimbi kunazo zonke, le nkinga iya ekudumeni ngisho nakubani. Ukuze imiphumela ye-overdosage kungenzeka ukuthi ithwale ukwephulwa okukhulu kwe-coagulability yegazi, kanye nezilonda zesibindi nezinso.

Isiguli esinezimpawu ezifanayo kufanele sigijimele esibhedlela. Ngeshwa, ayikho i-antidote ethize yanamuhla. Ukugcoba nge-gastric futhi kusebenze ukushiswa kwamalahle kusebenza kuphela uma umuthi ungakafiki. Ngenxa yenkathi encane yokubola, izinto ezisebenzayo zisuswa ngokushesha emzimbeni. Lapho kutholakala izifo nezinye izinkinga, ukwelashwa okuphawulekayo kwenziwa.

Isidakamizwa sinani?

Yiqiniso, ezigulini eziningi, isici esibalulekile ekukhetheni umuthi yintengo. Kumele kucatshangwe ukuthi isibalo sizoshintsha ngokuya ngendlela yokukhululwa kanye nesilinganiso, kanye nomuzi ohlala kuyo, umenzi, ikhemisi oyikhethile, njll.

Ngakho-ke umuthi "Lornoxicam" ungakanani? Izifo, noma kunalokho, amabhodlela amahlanu okulungiselela isisombululo, izobiza cishe ama-ruble angu-800-950. Amathebulethi angabizi kancane. Isibonelo, isidakamizwa esinomthamo we-4 mg sibiza ama-150-200 (amaphilisi ayishumi) noma i-350-450 (amaphilisi angu-30). Kodwa "i-Lornoxicam 8 mg" izobiza cishe ama-ruble angu-200-250 ngamaphilisi ayishumi. Ukupakisha izicucu ezingu-30 kubiza cishe ama-ruble angu-550-650.

Zikhona yini izihlobo eziphumelelayo?

Ngesizathu esisodwa noma esinye, akuzona zonke iziguli ezifanelekile iLornoxicam. I-analogues yomuthi, yebo, ikhona. Ezinye zazo zithengisa, futhi kulula ukuthola ikhemisi. Isibonelo, i- "Xefokam", "Lornoxicam" ne "Xefokam Rapid" - empeleni, imithi efanayo enezinto ezifanayo, kodwa kuphela kubakhiqizi abahlukene.

Kukhona amanye amatshini. Isibonelo, i-"Lorak" ibhekwa njengeyasebenza kakhulu, futhi inikeza nomphumela we-anesthetic ne-anti-inflammatory. Kungakhathaliseki ukuthi yikuphi, akufanele uzenzele imishanguzo futhi ungabandakanyi ngokweqile kusukela emithini yokwelapha umuthi "Lornoxicam". Ama-analogues angakhetha kuphela udokotela oya khona. Kuzoshintsha ukulinganisa kanye nemodi yokuthola, uma kunesidingo.

Ukubuyekeza odokotela neziguli mayelana nomuthi

Kulezi ziguli ezibekwe umuthi "Lornoxicam", impendulo evela ezigulini kanye nabaqeqeshi umthombo obalulekile kakhulu wolwazi. Ukuqala ngakho kufanele kubone umbono omuhle odokotela. Lesi sidakamizwa sisusa masinyane ukuhlukumeza futhi kusiza ukubhekana nokuvuvukala, ngakho-ke siyasetshenziswa kabanzi kumagatsha ahlukahlukene omuthi. Ngaphezu kwalokho, naphezu kohlu oluthakazelisayo lwemiphumela emibi, empeleni zilotshwe ngokungajwayelekile.

Iziguli zithini ngomuthi "Lornoxicam"? Ukubuyekezwa kulokhu kubuye kube kuhle kakhulu. Kokubili amaphilisi nama-injection kusiza ngokushesha ukubhekana nobuhlungu, futhi umphumela ovela kubo ungahlala emahoreni ayishumi. Amapayipi ahambisana nokukhathazeka okuncane, ikakhulukazi uma ulandela yonke imiyalelo. Mhlawumbe ukuhlukunyezwa okuwukuphela kwezindleko eziphakeme kakhulu, ikakhulukazi uma kuziwa ezixazululweni ezingenakulungiswa - akuwona wonke umuntu ongakwazi ukukukhokhela. Noma kunjalo, umuthi usebenza ngendlela efanele futhi ufanele imali.