Gamma-aminobutyric acid. Izimpawu ukuntula emzimbeni

Isilawuli eyinhloko umzimba wethu - ubuchopho. Siyabonga kuye, esihlelwe isenzo esenziwa zonke izinhlelo. singakwazi ukuqhubekela, ukubona, ukuzwa, abakhulumi, abanamizwa futhi futhi baqonde Ngosizo ubuchopho nomgogodla. Ngokwemvelo, lokhu kusho izinhlelo emaphakathi kanye neuropathy sezinzwa baphathe kungani leso senzo sabo esebenzisa izakhiwo ezikhethekile - neurotransmitters. Lezi zihlanganisa eziningi izinto ezisiza ebuchosheni okuwuphawu.

Isenzo neurotransmitters emzimbeni

Ukuze afeze ukudluliswa phakathi yezinzwa, kanye kwemisipha izicubu abasizi ezidingekayo. Ziyakwazi balamuli, okuyinto ukuqhuba imiyalezo edluliselwa ngogesi yonkana isikhala izinhlaka zokuxhumana zobuchopho. I pulses ezisebusweni eziyimpumelelo nerve futhi, engakafiki ekupheleni, kubangela ukukhululwa kwe neurotransmitter. "Abasizi" iwela igebe sinomthelela namangqamuzana ezinzwa elingumakhelwane, okuyinto kuba permeable isignali. Ngakho-ke idluliselwa zonke pulses kagesi emzimbeni. Neurotransmitters - into Lokudabuka zamakhemikhali, okungase kubangele kokubili excitation futhi okusithiyayo e isimiso sezinzwa esiyinhloko. Basuke zihlukaniswe ngamaqembu 3: ama-amino acid, peptides futhi catecholamines. Laba bameleli be-ezivamile epinephrine futhi norepinephrine, gamma-aminobutyric acid, glycine, Dopamine, serotonin, glutamate, acetylcholine.

Gaba imisebenzi emzimbeni

Gamma-aminobutyric acid (isiNgisi Gaba) ohlobene balamuli ukuthi zivimbela isimiso sezinzwa. Kuyinto ikhemikhali samanje kubantu nasezilwaneni. Gaba ingenye acid ezibalulekile acid, okuyinto abakwazi synthesize amaprotheni molecule. Naphezu kwakho konke lokhu, ukubaluleka kwayo emzimbeni likhulu kakhulu. Gamma-aminobutyric acid wenza imisebenzi emibili ebalulekile:

1. isinyathelo Neurotransmitter. Ngenxa umphumela wawo inhibitory ka Gaba has a hypotensive, sine imiphumela anticonvulsant. Ngaphezu kwalokho, kwenza ukukhuthazwa ubuthongo, ulawula motor umsebenzi, ngcono izinqubo memory nokucabanga.
2. umsebenzi umzimba. Gaba kuthuthukisa izinqubo umzimba kwenza ubuchopho nokugeleza kwegazi, njengoba amangqamuzana ezinzwa e anikeza umzimba amandla. Ngenxa yalolu ketshezi Kwenziwa omunye imiphumela ezinkulu - anti-hypoxic, okusho kugwenywe-mpilo indlala. Okulandelayo isenzo Gaba - ukususwa imikhiqizo umzimba emzimbeni futhi nemiphumela ukukhuthazwa ukukhiqizwa hormone ukukhula by the pituitary anterior.

Imithombo ye-gamma-aminobutyric acid

Gaba ingenye yezingxenye yegazi nobuchopho izicubu. Nge ukuntula alondoloza zemvelo kubalulekile wayithola evela kweminye imithombo. Gamma-aminobutyric acid elikhona imikhiqizo abanye isitshalo. Bahlanganisa itiye nekhofi amahlamvu, isikhunta filamentous, kanye ijusi uhlobo izitshalo cruciferous. Ngaphezu kwalokho, Gaba ibhalwe esebenzisa amakhemikhali usebenzisa izindlela microbiological. Ukuze ukuthuthukiswa yayo usebenzisa amagciwane womuntu coli. Kwezinye imithi aqukethe ikhemikhali eyisisekelo - nicotinoyl gamma-aminobutyric acid. Libhekisela analogs etholwe elabhorethri.

Izimpawu nokuntuleka Gaba emzimbeni

Ngezinye yokuntuleka gamma-aminobutyric acid, eziningi izinqubo sokugembula. Khona-ke abakhululiwe eziyinhloko - ukucindezeleka kwengqondo, ukukhathazeka, futhi imisipha amajaqamba. Lihlobene nokubhekana ubuso imisebenzi encishisiwe kwenziwa emzimbeni ye-gamma-aminobutyric acid. Gaba kuyadingeka ukunikeza nobuchopho amandla, ukulawula izinqubo ezenzeka kuwo. Ngakho-ke, lapho ukuntula yayo eba eziningi CNS iziyaluyalu. Lezi zihlanganisa:

1. Cerebrovascular isifo - umfutho wegazi ophakeme, isifo sokuqina kwemithambo yegazi, isifo sohlangothi kanye inhliziyo ukuhlaselwa.
2. Ukuphathwa yikhanda, ubuthakathaka, isiyezi, ubuthongo thuthuva, inkumbulo, ukunakwa.
3. Isifo sokuwa.
4. Alzheimer.
5. cerebral palsy.
6. Encephalopathy.
7. Ukwandisa izinga hormone ukukhula.
8. Dementia kuyinto nokulimala engqondweni.
9. Parkinson.
10. uthi futhi bacindezeleke.
11. Hypoplasia izinqubo kwengqondo izingane.
12. isimo engazethembi sezinzwa nangokwengqondo.
13. Ulwandle kanye nomoya ukugula.

Zonke lezi zifo zidinga imithi ukugcwaliswa gamma-aminobutyric acid, kanye ukusetshenziswa kakhulu umkhiqizo lapho kuqukethwe.

Imithi equkethe Gaba

Ukuze ukulungisa ukuntuleka gamma-aminobutyric acid, ukufuna usizo lodokotela. Iyoyimisa i replacement therapy ezanele. Ingqikithi eyisisekelo zonke izidakamizwa - asidi gamma-aminobutyric. Analogs iqukethe izithasiselo ngesimo calcium, nicotinoyl, futhi amagama ahlobene of Gaba. Izidakamizwa eziyinhloko nemithi "Aminalon", "Pikamilon", "Phenibut", "Neyrobutal", "ka-Gaba". Izinkomba ngoba ukusetshenziswa zonke lezi izidakamizwa lezi zinkinga kubangelwa ukuntula gamma-aminobutyric acid emzimbeni. Ukuthaka imithi aqukethe Gaba contraindicated ezinganeni ezingaphansi kweminyaka 1 unyaka abesifazane abakhulelwe (e senyanga yokuqala), hypersensitivity ukuba izinto main noma asizayo futhi ukwehluleka oyingozi so-renal.

Gamma-aminobutyric acid: Nobufakazi

Ekumisweni Gaba noma analogue yayo in iziguli kahle kakhulu anda, ukulala futhi sihlale siphapheme imigomo, kukhona inkumbulo ngcono nokwehlisa uthi futhi bacindezeleke, iboshiwe Ukudlikizela. Phakathi imiphumela emibi, ezinye iziguli ukubika dyspepsia, libido yanda, ukozela.