"Ekskhol": imfundo manual, izibuyekezo, izithombe, ifomu ukukhululwa, isakhiwo

Emizimbeni yethu kukhona isitho esingavamile esingaphakathi uyakwazi ukunciphisa - lena isibindi. Ngaphansi kwethonya izici ezihlukahlukene okungekuhle, lokhu insimbi bacindezelekile omkhulu, futhi amaseli ukufa noma zibe izicubu fat. Ekwelapheni isibindi isetshenziswa izinhlobo eziningi zezidakamizwa, enye yazo - "Ekskhol". Yokusetshenziswa zomuthi, izimpawu, contraindications, ikakhulukazi yokwelapha kanye neminye imininingwane ewusizo kungatholakala kulesi sihloko.

Khipha ifomu kanye nokwakheka

Lesi sidakamizwa itholakala ngendlela amaphilisi, ngamunye equkethe ketshezi asebenzayo - ursodeoxycholic acid isamba 250 mg, futhi izingxenye asizayo: Silicon dioxide, i-magnesium stearate, i-calcium hydrogen phosphate dehydrate, povidone, monohydrate lactose, nabanye.

Kanjani imisebenzi izidakamizwa?

Izici yemiphumela yokwelapha izidakamizwa "Ekskhol" imfundo manual uchaza ngendlela elandelayo: kuba izidakamizwa hepatoprotective ne umphumela choleretic. Ingqikithi abaphuma njalo seliphindeke izikhathi miphumela elandelayo:

• kunciphisa zamagama cholesterol isibindi, kunciphisa ukumuncwa yayo emathunjini bese okuqukethwe kule Bile;
• It kwandisa izinga cholesterol nokonakala e Bile excretion uhlelo, inkanuko ukwakheka kanye uketshezi of nokuncipha lithogenicity zabo;
• Kuvuselela ukuvelela ezingeni Bile acid;
• It sithuthukisa uketshezi of esiswini kanye uketshezi pancreatic;
• It kwandisa umsebenzi enzyme lipolytic;
• It has umphumela hypoglycemic;
• Kuvuselela ukumuncwa esinqunyiwe noma Imininingwane cholesterol amatshe ezifana;
• kunciphisa saturation Bile ne cholesterol, nekhuthaza kusukela amatshe;
• It has izakhiwo immunomodulatory, esiphatha impendulo izindlela esibindini;
• kunciphisa Inkulumo antigen, wagxila hepatocyte uhlelo ulwelwesi;
• ulawula inani T-lymphocyte, i-interleukin-2;
• Kunciphisa inani elzinofilov.

Yini pharmacokinetics izidakamizwa?

Ukulungiselela "Ekskhol" yokusetshenziswa alokhu ezichazwe kulesi sihloko, ngezinga eliphezulu ukumuncwa emathunjini amancane kanye nekhono ukuwela placenta. Inkomba makismalnaya lokuhlushwa izidakamizwa egazini kufinyelelwa ngemuva kwamahora 1-3, okulinganako 5.5 mmol / l. Ursodeoxycholic acid ngokuyinhloko eboshiwe plasma amaprotheni futhi akheka kumaseli sesibindi esingelapheki kubantu abangamaphesenti glycine kanye taurine conjugates yefomu, okuyinto adedelwa Bile. imikhiqizo umzimba kuthiwa excreted endleni yabantu abanaleli by 50-70%. Inani elincane lemithi asebenzayo ingashintshiwe engena amathumbu, lapho amagciwane siguqulelwa lithocholic acid, sulfated esibindini futhi amathumbu excreted ngokuphelele.

Ukukhombisa umthamo?

ubufakazi okuqondile yokwamukela lesi sidakamizwa "Ekskhol" imfundo manual libhekisela kwale mibandela elandelayo:

• eyinhloko biliary isifo sokusha uhlobo ngokungabi bikho decompensation;
• isidingo sokuchitha cholesterol amatshe amancane naphakathi no-isayizi, inqobo gallbladder;
• kolwelwesi (Reflux biliary);
• ezingamahlalakhona asebenzayo-hepatitis uhlobo;
• isifo sesibindi esingelapheki kubantu abangamaphesenti ukuluthwa utshwala;
• sclerosing cholangitis ukuma eyinhloko;
• cystic fibrosis kwesibindi;
• nonalcoholic steatohepatitis nemvelo;
• diskenziya ipheshana biliary.

Kulezi izinkomba amaphilisi kanye amaphilisi "Ekskhol" ngokuvamile ebekwe udokotela futhi ulubonise ngayo ukusebenza kahle eliphezulu.

Izimo

Ukulungiswa equkethe ursodeoxycholic acid, is contraindicated lezi zifo ezilandelayo:

• khona hypersensitivity kuya izingxenye zomuthi;
• yokuntuleka umsebenzi evamile, futhi empyema we gallbladder ;
• khona amatshe nge ingxenye enkulu ye-calcium, Kutsho X-ray;
• fistula e pheshana emathunjini;
• kwesibindi kohlobo uhlobo;
• wamathumbu ukuvuvukala isifo uhlamvu;
• cholecystitis, cholangitis noma esigabeni acute;
• isifo sokusha decompensated;
• isifo gallbladder futhi Amapayipi alo namathumbu;
• Nokukhulelwa kanye lactation;
• Izingane ezingaphansi kweminyaka engu-3 ubudala;
• esingamahlalakhona kwezinso futhi hepatic;
• Bile ipheshana isimiso O.

Uma kukhona Izimo idatha akunconyelwe iziguli ukulungiselela "Ekskhol". Manual ibonisa ukuthi ithuluzi akazange abonise imiphumela emibi embungwini ezifundweni ezilwaneni, kodwa izifundo ezanele kwabesifazane abakhulelwe baye akazange enziwe.

Izixwayiso

Ngokukhethekile kubonisa ezinye umehluko wemisindo nemiqondo yamagama ethola izindlela "Ekskhol" imfundo manual. Odokotela ngalokhu ukulungiselela akhayo, kodwa zinaka abesifazane yokuzala ukuthi yokwelapha lezi farmproduktom kufanele banakekele inzalo eyengeziwe. Ngaphezu izinto zokuvimbela inzalo hormone, okuyinto kunciphisa ukusebenza kahle, ukusebenzisa izindlela okuvimbelayo ukuvikelwa ukukhulelwa okungafunwa. Akunconyelwe kwabesifazane abakhulelwe zifa linqume ukwelashwa izidakamizwa "Ekskhol". Manual ibonisa ukuthi kulesi simo ingozi unina kumelwe kube ngaphezu kuka ingozi embungwini. Uma lokhu imithi lactating abesifazane kufanele ayeke lactation.

Uma leyo ngane izokwazi engu-3 ubudala, lesi sidakamizwa "Ekskhol" ingase yabelwe ke uma kunesidingo. Yokusetshenziswa izingane kudinga ngokuqapha ekwelapheni izingane kuze iminyaka 4, njengoba kungenzeka ukuthola kunzima ukugwinya amaphilisi.

Indlela ukusebenzisa imithi?

Umhlahlandlela engcono yokwelapha izidakamizwa "Ekskhol" - yokusetshenziswa. Izithombe leli thuluzi kuyokusiza uzivikele ukuthenga mbumbulu.

Umuthi iqondiswa ngomlomo, okungcono zakusihlwa. Hlafuna amaphilisi akunconywa, kungcono uphuze amanzi kangcono nomqulu omncane. Uma isiguli ukala engaphansi kuka-34 kg, kungcono ukuba ukhethe ukumiswa ne izidakamizwa unesimo esifana.

Isikali incike yobudala kanye imigomo yokwelapha.

Enombono eqhekeza amatshe atholakala enyongweni futhi Amapayipi "Ekskhol" thatha imali nsuku zonke 10 mg / kg izinyanga 6-12 futhi ngemva kwezinyanga ezimbalwa imiphumela prophylaxis.

Uma awukudla nesineke Reflux kolwelwesi, waye uDavide esenza okusesikweni eyodwa capsule zomuthi kanye ngosuku umjikelezo amasonto amabili ukuba ezinyangeni eziyisithupha, futhi lapho isidingo ethize - izinyanga 24.

Ukwelashwa isifo sokusha biliary kukhiqizwa ngokuvumelana isikimu: Usuku - 10-15 mg / kg nge ubude ngokubona kwalo dokotela.

Nezinye izifo kufakwe uhlu izinkomba yokwamukelwa, lo umthamo kanye nobude udokotela wakhe yokuvuma isethi umuntu ngamunye.

Futhi, indlela ekhethekile kudinga ukuqashwa kukaNksz izingane nentsha "Ekskhol" izidakamizwa. Yokusetshenziswa ezinganeni abaneminyaka engama 3 mazwi aveza isidingo lokuqoka umthamo 10-20 mg / kg esisindo ngosuku. isiqondiso eqondile zomuthi kanye nesikhathi yokwelapha kuqinisekiswa udokotela ngamunye.

Ingabe ikhona imiphumela emibi yokwelashwa futhi yokweqisa?

Esikhathini ukusabela ezingezinhle kungenzeka ngenkathi ethatha "Ekskhol" izidakamizwa, njenge:

• ubuhlungu emuva;
• iziyaluyalu wokugaya ukudla;
• transaminases isibindi ukwanda umsebenzi;
• komzimba;
• ukugcwaliswa-calcium amatshe atholakala enyongweni;
• retsediv psoriasis;
• Alopecia.

Uma uhlangabezana miphumela okufanele ukuyeka ukuphuza "Ekskhol" izidakamizwa. Yokusetshenziswa, okwakhiwa kwalo ekufinqweni is okwethulwa kulesi sihloko sisikisela ukuthi izimo izidakamizwa ukweqisa izidakamizwa aye atholakala. Nokho, uma isiguli inezimpawu lokudakwa ezidingekayo ukukhiqiza therapy okunezimpawu.

Inhlanganisela nezinye izidakamizwa

Co-ukuphatha nge antatsianami alyuminiesoderzhaschimi futhi ion exchange inhlaka, ekunciphiseni nekusebenta ukumuncwa "Ekskhola". ejenti lipid-ukwehlisa, estrogens neomtsin noma progestins ezandisa saturation Bile cholesterol nokwehlisa nokuqedwa amatshe.

Izici izindlela kokuthola

Incwadi yokuqala ukuthi kufanele ufunde ngaphambi kokuthatha "Ekskhol" izidakamizwa - yokusetshenziswa. Khipha uhlobo izidakamizwa amaphilisi izenzo yimpumelelo kakhulu maqondana ngokugcwele cholesterol amatshe kabani usayizi ingeqi 15-20 mm. Kulokhu, lo gallbladder kumelwe sisetshenziselwe izinhlangano idatha akuzona ezingaphezu kwesigamu, kanye Amapayipi 100% agcinwayo umsebenzi wabo ekususweni Bile.

Ngokuhamba yokwelapha ukuncibilikisa cholesterol imali, kudingeka ukulawula umsebenzi enzyme isibindi, transaminases, phosphatase ane-alikhali, GGT futhi bilirubin. Uma njalo emavikini 4 njalo ezinyangeni 3 zokwelashwa kufanele kwenziwe cholecystography. Njalo ngemva kwezinyanga eziyisithupha, isiguli kufanele ibhekane isibindi ultrasound ukuhlola nokwelashwa ngempumelelo.

Uma sekuphelile eqhekeza amatshe reception "Ekskhola" umiselwe kufanele waqhubeka izinyanga ezintathu nokuqedwa sokugcina amatshe engabonakali futhi kuvimbele kumiswa amasha.

Uma ku-nyaka engxenyeni yokuqala ka ukwelashwa ningagcini ngisho kancane chaza amatshe, kuba inexpedient ukuze uqhubeke nokwelashwa ngenxa nokungasebenzi ngendlela yayo.

Analogs futhi omqondofana

Uma isiguli ezinye zezizathu umgomo alinakunikezwa "Ekskhol", kungaba kuthathelwe indawo omunye omqondofana:

• Amaphilisi Abonayo "Ursodeoxycholic acid";
• Amaphilisi Abonayo "Ursol";
• Amaphilisi Abonayo "Ursosan";
• amaphilisi ifilimu-camera "Ursodeks";
• Amaphilisi Abonayo "kwesikhombi Rompharm";
• kpsuly "Urdoksa";
• ukumiswa for reception yangaphakathi "Ursofalk";
• Amaphilisi Abonayo "Ursofalk";
• "Ursol" capsule;
• amaphilisi ifilimu-camera "Livodeksa";
• "Grinterol" capsule

Uma isici esiyingqayizivele ngesineke ursodeoxycholic acid, noma-ke kuye kwaba khona lokhu akuphumeleli ekwelashweni, kungenzeka ukuba esikhundleni isidakamizwa i-analog, okuyinto ifomu ithebhulethi "Holenzim". Lesi sidakamizwa eyisidalwa esinenkululeko inhlanganisela ehlanganisa Bile izicisha dihydrated izicubu pancreatic futhi lwamafinyila mncane imfuyo esiswini. Ngo senzo "Holenzim" libhekisela Cholagogue. Lesi sidakamizwa is contraindicated ku hypersensitivity, futhi exacerbation okukhulu pancreatitis ezingamahlalakhona. Njengoba uhlangothi ukusabela kusuka ngokuthatha izidakamizwa komzimba kungenzeka ngesimo ukuqubuka Ukubhidliza, ububomvu, futhi isikhumba.

Izindleko kanye nesineke kobufakazi

Lesi sidakamizwa kuveza inkampani eyenza imithi yasekhaya Zao "Kanofarma ukukhiqizwa", esemgwaqweni esifundeni Moscow. Izindleko iphakethe "Ekskhola" Ngokwesilinganiso eRussia ruble 125. Iziguli eziningi bathi ukuphumelela izidakamizwa, kube lula reception yayo futhi intengo imali. Abantu ne isifo sesibindi futhi ipheshana biliary kuqashelwe ukuthi imiphumela emihle kufezekiswe ekwelapheni "Ekskholom". Kanye nekghono weziguli wabika tolerability ezinhle izidakamizwa.

Kufanele kuqashelwe ukuthi incazelo izidakamizwa akuphelele. Ukuze uthole ukwaziswa enwetshiwe mayelana izidakamizwa "Ekskhol" kufanele bajwayelane iziyalezo ezinikeziwe iphakethe wezokwelapha. Inhloso yalesi thuluzi nje kuphela udokotela ukuba khona. Ukuzelapha kungaba yingozi empilweni yakho.