C-peptide namazinga insulini

C-peptide - kohlobo ezihilelekile ekwakhekeni we-insulin. Kuyingxenye engqamuzaneni proinsulin. Insulin - Lapho C-peptide is wajinge wanamatsela kusukela engqamuzaneni proinsulin, material olusha luvela ngenxa yalokho. Lokhu kuyizinhlayiyana, efana insulini, zingase igazi lomuntu. Nokho, nokwahlukana okokusebenza kancane kakhulu noqhekeko we-insulin, ngakho isilinganiso phakathi kwalezi izinto ezimbili egazini kulingana 5 kuya e-1 umusa we-insulin. Futhi ngakho kuphumelela kangcono ukuthatha ukuhlaziya C-peptide egazini kuka-insulini.

C-peptide - material eziphila besahlanganyela, futhi eqinisweni udlala indzima kuphela - kumiswa we-insulin. Amaseli proinsulin kunezinhlobo ezimbili eyinhloko peptides - A no B. uxhuma nabo nomunye yesithathu, S. C. Ngokushesha ahlubukayo A no-B, kwakhiwa insulin. Empeleni, kuba linchpin, okuyinto sdergivaya nge proinsulin, ukunikeza i-hormone oyifunayo. Kuyinto eyabonisa inani insulin C-peptide. Jwayelekile kokuzila ke zokhahlamba kusuka 0, 53 2, 9 ng / ml. Phakathi imali lezi izinto, kukhona ubuhlobo ngqo. C-peptide luyanda - ngakho, futhi insulini anda. Ngaphezu kwalokho, ukuhlaziywa kwalokho peptide lokwasungulwa eyayenziwe ukusiza ukuhlukanisa insulini ezivezwa emzimbeni. Ngokungafani ama-hormone ezibalulekile, okuyinto kudingeka kangaka ukucutshungulwa glucose, C-peptide awahlobene receptor isibindi, futhi ukuzungeza kuba lokuhlushwa efanayo e vein portal. Futhi, ihlaziya kungenzeka ukuhlola isimo β-amaseli kwamanyikwe zabantu abaphethwe isifo sikashukela futhi baphathwe i-insulini eyayenziwe busuka umzimba. Futhi novivinyo olunjalo eyonquma futhi sihlaziye ekushintshashintsheni amazinga insulin ngesikhathi ukubambezeleka yayo esibindini.

Futhi manje kancane xaxa. Proinsulin kuveza pancreatic beta amaseli. Ngaphezu kwalokho, le nto ahlahlele ibe ikhemikhali kusukela leli phuzu cishe akudingeki umzimba womuntu, futhi hormone ezibalulekile. Nokho, ungakwazi ukuqhathanisa lezi izinto ezimbili eziseduze abangekho ndawo ngaphandle nomunye. Kulokhu C-peptide futhi insulini akhona, ngoba kokubili zenziwa athi unesimo esifana. Yingakho isibalo C-peptide yisikali sokuthi umsebenzi futhi amaseli beta futhi amazinga insulin emzimbeni. Uma ngesizathu esingaziwa, amasosha omzimba iqala ukuhlasela ku amaseli obandakanyekile ekukhiqizeni insulin, kulesi simo sithola a sikashukela ezingeni lokuqala. Ngamanye amazwi, igazi glucose aqoqana kakhulu, kodwa asingeni amaseli, njengoba "ukhiye" kuye cell-insulin, okuyinto, ngeshwa, ikhiqizwa ayisekho. Uma amangqamuzana nganoma yisiphi isizathu, abangazilaleli amasignali kwale hormone-ke, ngomqondo ongokomfanekiso, iminyango iseli kungukuthi livulekile, bengaweli glucose. Kulokhu, ezingeni lesibili wabonakaliswa sikashukela. Isithombe kuyafana - amazinga igazi glucose kancane kancane iqala sizoya ukuziphilisa, futhi ukubeka lokhu glucose ukuya, ngoba ungase uthole amaseli bengayi. Nokho Kuyinto ngokuvamile inkomba owaziwa insulin anda, yize zingancishiswa kuleli cala.

Amaseli musa uzwa ukwexwayiswa elilodwa amahomoni ezibaluleke kakhulu kwamanyikwe ngokuyinhloko ngenxa yokuthi kukhona ukwephulwa zezinto ezibangela ukukhuluphala. Kungenxa yalesi sizathu ukuthi isifo sikashukela singabonakali ngaphandle ezingeni lesibili namanje uvame ukubizwa ngokuthi 'abantu okhuluphele sikashukela. " Ngo sikashukela uqimba ezingeni C-peptide ingezansi ezingeni lesibili efana evamile futhi sikashukela mkhulu kunezinhliziyo kunesidingo. Ngakho, endabeni yokuqala ayikho insulini, ngakho-glucose abakwazi ukungena ku amaseli. Okwesibili - kuba, ngisho ngobuningi, kodwa amaseli ningalaleli, ngakho njengoba glucose ngeke ungene amaseli. Ngamanye amazwi, indaba okuyilona elidingekayo ukuze umuntu umsebenzi yeselula, ekubeni ezingafinyeleleki kubo. Futhi kungani sikashukela - njengoba isifo esiyingozi.

Izinga C-peptide kuyehla noma ukwanda kwemithwalo parallel kusezingeni insulini. Uma le nkomba usegazini likhona eziningi enganele, i-hormone isiqondiso futhi understated. Ngakolunye uhlangothi, uma le C-peptide kakhulu, ukuthi cishe kusikisela ukuthi insulini kanye ngokweqile. Kunezizathu bikho, futhi hormone ngokweqile, esinikela amandla amaseli, futhi ngaso sonke isikhathi ezihambisana sikashukela. Kaningi kuyenzeka ukuthi C-peptide futhi ephakeme kunaleyo evamile ngenxa insulinoma noma esingamahlalakhona kwezinso ngefomu ezingamahlalakhona. Nokho, ukwehla yayo uvame okubangelwa ngenxa yesifo sikashukela.