"Bonviva": ukubuyekezwa. "Bonviva": yokusetshenziswa, intengo

Kungabonakali futhi ngokushesha hamba iminyaka. Muva nje, intombazanyana ngeqholo ukuhambahamba emgwaqweni ngesitifiketi iziqu. Kubonakala kwakungeyona eside, futhi kakade umama osemusha esihambisana nezingane zakhe lapho ziya esikoleni. Iminyaka yadlula, futhi lapha usuvele abazukulu zikhula. Autumn zokuphila ... Kuyinto kulonyaka, futhi owesifazane Ubamba nobulwelwe njengoba postmenopausal kwamathambo. Lapho lesi sifo ziyaqothuka kakhulu futhi athambekele waphuka kukhona amathambo. emakethe yesilungu yanamuhla ilungele ukunikela amakhasimende ayo uhlu enkulu ngokwanele izidakamizwa ezisiza ngempumelelo ukubhekana nalesi sifo esesabekayo. Eminye imishanguzo yesimanje kakhulu futhi umuthi "Bonviva".

mshini Action

The main isithako zomuthi - Ibandronic acid. Le ngxenye kuvimbela futhi kuvimbela amathambo ekubhujisweni. Ngaphezu kwalokho, lokhu izidakamizwa ngempumelelo kuvimbela amathambo resorption (oncelayo), kuyilapho Nokho hhayi ezithinta ngqo ukwakheka ithambo izicubu. Ngaphezu kwalokho ibandronic acid ekwakhiweni njengenhlangano ingxenye asizayo kuhlanganisa plasdon K-25, monohydrate lactose, crospovidone, stearic acid, aerosil.

Imithi "Bonviva" imfundo manual ichaza ukuthi ukuxazulula lokho kubambezela buyekeza ithambo izicubu kwabesifazane ngesikhathi menopause ezingeni ngazo owesifazane oseminyakeni yokuzala. Ngenxa yalokho, umsebenzi kwandisa amathambo eqinile futhi bone amaminerali kwabantu, kwehlisa eqhekeza izici ithambo kuyi-collagen. Ngokuvamile, ibandronic acid kuyinto into ephumelela kakhulu kokuba wonke ezahlukene zokwelapha. Ngenxa yalesi sizathu, "Bonviva" ingasetshenziswa okuphulukisa ngokuhamba kwesikhathi elinesimo nokushintsha kokudla nokufakwa ngokwanele nezimo.

Izibuyekezo Medical ( "Bonviva" usefake bazuza idumela elihle njengezisebenzi emakethe ezithaka imithi) zisikisela ukuthi umuthi ngokushesha ugxile pheshana emathunjini. Ukuze kwesikhathi esithile ngemva kusukela emizuzwini engu-30 ku-2 wokubuka lokuhlushwa walo omkhulu e oketshezini olungenambala lwegazi. Komkhiqizo igazi emqulwini ka 40-50% we isamba wathola lingena singene kwezicubu amathambo, futhi kukhona inqwaba yalo. Ngisho ezinye izidakamizwa nakanjani plasma amaprotheni. Yonke enye into ngeke aphume emzimbeni by nezinso.

Ngokusho izifundo zokwelapha, ingxenye eyinhloko "Bonviva" ngokulinganayo kuthinta abesilisa nabesifazane. Azikho umehluko obonakalayo ukusatshalaliswa ibandronic acid phakathi izinhlanga European nase-Asia. In iziguli abadabuka Afrika, zikhona ezinye umehluko ukusatshalaliswa esebenzayo izidakamizwa "Bonviva".

I abathengi main

Tablets "Bonviva" ayatholakala imithamo emithathu: 2.5 mg, 50 mg 150 mg. Ukulungiswa at umthamo 2.5 mg is ikakhulukazi esetshenziselwa ukwelapha nokuvimbela kwamathambo e abesifazane postmenopausal. I nomuthi e umthamo mg 50 isetshenziswa ezahlukene ebanzi kakhulu izifo. Izindawo ezinkulu zokwelapha zihlanganisa izifo ezifana izilonda metastatic ithambo (isidakamizwa ukunciphisa ingozi hypercalcemia), sokugembula waphuka nemvelo. Tablets futhi ubuhlungu ukuthi umthamo zingancishiswa, ukwehlisa isidingo nezinqubo ukwelashwa ngemisebe ngoba ubuhlungu futhi ngezingozi ukwa. Lezi esenikwe yokwelapha ukwelashwa iziguli hypercalcemia ka umdlavuza ngemuva.

Izibhebhe 150 mg - abathengi salable kakhulu nomuthi "Bonviva". Yokusetshenziswa (intengo impela high, kodwa lokhu umthamo kumele kuthathwe 1 isikhathi ngenyanga, okuyinto ekahle kakhulu) ulawula iphilisi nokuvimbela waphuka e kwamathambo postmenopausal kwabesifazane. izifundo zokwelapha luye lwabonisa ukuthi umthamo owodwa we-150 mg is njengoba nomphumela njengoba isicelo nsuku zonke phakathi nenyanga ka-izibhebhe 2.5 mg.

Ngaphezu okungenhla, sisetshenziswa kabanzi olunye uhlobo imithi "Bonviva" - imijovo. Esikhathini ngobuningi ze umthamo lwemithi kanje: umjovo 1 njalo ezinyangeni 3. Mangisho ukuthi kwabathinta "Bon Vivant" lunamandla ngokwanele, ngoba ukwelapha leli fomu esingayilindela iyiphi izigigaba ezingezinhle. Ngaphambi isicelo ngqo ikhambi kubalulekile ukuba zibukeke uhlolele khona ukungcola, sinake umbala waso.

Ngenisa izidakamizwa ngemithambo yegazi, ukusakaza, imizuzwana engu-30. Inqubo wenziwa kuphela nochwepheshe wezokwelapha. Lapho iqhube yini edingekayo ukuze ugweme kokuthola isisombululo zibe umthambo kule nezicubu eziseduze vein.

Izici isicelo

Iziguli kwamathambo, ochwepheshe kuvame ebekiwe ukuthola tablet elilodwa (umthamo - 150 mg) kanye ngenyanga. Nokho, kufanele alandele imithetho ethile yokwemukela ukulungiselela "Bonviva" isinyathelo ngempumelelo.

Umuthi kakhulu kabi ugxile lapho ahambisana ukudla reception noma aphuze (ngaphandle amanzi elula non-carbonated). Njengoba kushiwo ngaphambili, "Bonviva" amaphilisi zithathwa ngamunye ngamunye 1 isikhathi ngenyanga. Kodwa kakhulu, ofiseleka kakhulu ukuthi izidakamizwa esithathwayo ngosuku olufanayo. Uma ngasizathu simbe usuku nakhelwe izidakamizwa abaphathi, waphasiswa, ithebhulethi kufanele kuthathwe, okungenani ngesonto elilandelayo. Uma lesi simo asiphumeleli, kusho ukuthi i-reception kufanele zihlehlise kwaze kwaba usuku esinqunyiweyo senyanga elandelayo. Uma sikubeka kalula, ngokuphelele engamukeleki ukusebenzisa ithebhulethi 2 umthamo 150 mg ngeviki elilodwa.

Thatha imithi kufanele kube okungenani imizuzu engu-60 ngaphambi kokudla noma ukuphuza okunye. Abantu ababefika babedla amakhasi noma chaza amaphilisi is hhayi Kunconywa, kumele kugwinywe lonke aphuze ingilazi yamanzi okumsulwa (akukho amaminerali kanye carbonated). Ngemva imithi likhishiwe, ngesikhathi 1 chasa ongenakuqamba amanga, umzimba kumele kube sesimweni mpo.

Izimo ethola "Bonviva"

Njenganoma yimuphi neminye imithi, "Bonviva" imfundo manual (intengo izidakamizwa uyoboniswa ngezansi) alikukhuthazi ezigulini hypersensitive emuthini noma ukungabekezelelani yabo. Izazi zezempilo neze akunikeze imithi ukuze iziguli izifo ezifana ahalatsiya futhi stricture ngomphimbo, hypocalcemia, zikashukela-galactose malabsorption. Kuyinto ukusetshenziswa engamukeleki imithi abantu abane ukungabekezelelani galactose, lactase ukuntula. Hhayi esimisiwe (naphezu Izibuyekezo positive) "Bonviva" izingane nentsha abaphethwe kwamathambo.

Kakhulu ngokucophelela odokotela linqume izidakamizwa iziguli kokuba nezinkinga pheshana emathunjini (isilonda, duodenitis, kolwelwesi, dysphagia, emphinjeni Barrett sika). Ngaphezu kwalokho, noma yimuphi izinqubo acute sokugembula esiswini emphinjeni ukuba laba isisekelo segama ukuhoxiswa izidakamizwa noma okungenani uthintane onguchwepheshe.

Akubonisi imithi "Bonviva" (imijovo, amaphilisi - noma yiluphi uhlobo ukukhululwa) kubantu besifazane abakhulelwe. Isizathu salokhu - ngokungabi bikho isipiliyoni emtholampilo.

Overdosing side effects

Emva kokuthola iphilisi lokuqala kwezinye iziguli zingase zibhekane emuva kokutshengisa izimpawu zomkhuhlane omnene. Ukuthatha noma iyiphi izinyathelo ezikhethekile kulokhu ayidingekile.

Lapho edlula ngemithamo ovumelekile kungabonakala nasemkhakheni ezinye imiphumela emibi. On the ingxenye pheshana emathunjini kungenzeka ukubonakaliswa njengesifo sohudo, dyspepsia, isilonda, duodenitis, kolwelwesi. Kaningi, "Bonviva" (Umyalelo, kobufakazi nesineke ubufakazi) kungabangela isicanucanu, ukuhlanza, ubuhlungu besisu, ukuqumba, dysphagia. Kulezi ukubonakaliswa sinqobe isihlobo angabhekwa ubisi antacids. Ukuzama eyayenziwe ntombazane ukuhlanza ukugwema ingozi angeke kulimaze ulwelwesi emphinjeni.

uhlelo zemisipha angaphendula yokwamukela izidakamizwa imisipha ukuqina kanye izinhlungu zibe, myalgia, arthralgia. Ezimweni ezingavamile, wandise nengozi yokuba osteonecrosis emhlathini ngokumelene isizinda umdlavuza. Ngakho-ke, udokotela wamazinyo kufanele baziswe ukuthi isiguli kuthatha "Bonviva" yakhe ukuhlola isilinganiso inzuzo / ingozi, futhi unqume ukuthi kokungenela kuhlinzwa kulesigaba inkambo ukwelashwa.

Isiyezi nekhanda angaphendula "Bonviva" isimiso sezinzwa. Ngaphezu kwalokho, eziningi ngangokunokwenzeka komzimba ezifana urticaria, ukuqubuka, angioneurotic edema nemvelo. Kungase kube buthaka, iqolo. Sicela uqaphele ukuthi ukwehluleka ukuhambisana eziyalezweni nokushintsha kokudla nokufakwa kungase kwandise amathuba okuba nemiphumela engemihle evela isimiso sokugaya ukudla bungene.

Imicimbi ngaphambi kokuqala ukwelashwa Yiqiniso

Ngaphambi kokuba uqale ukusebenzisa noma iyiphi umthamo imithi, "Bonviva" imfundo manual (intengo incike kundlela yokukhululwa umthamo) uncoma ukuba banake ezingeni-calcium emzimbeni. Uma kukhona izimpawu of hypocalcemia, iyiphi kwezinso ngaphezulu amathambo umzimba electrolyte ibhalansi, kumakhasimende angaba namandla "Bonviva" kufanele kube eliningi eyanele ukwenza Ca2 ⁺ futhi kavithamini D. Ukuthola noma yiluphi olunye bisphosphonates kuphakamisa ngokuvamile ukwephulwa ngokwanele ngesikhathi nokugwinya, ukuthuthukiswa esophagitis, ukwakheka izilonda emathunjini esiswini emphinjeni. Ukunciphisa lezi zimpawu ezingemnandi, kubalulekile ukuba banamathela izincomo (isikhundla mpo umzimba kungakapheli imizuzu 60 ngemva kokufaka i-"Bonviva").

Uma uqaphela izimpawu ngomphimbo izilonda imithi "Bonviva" yokusetshenziswa (kobufakazi nesineke ubufakazi) welulekwa ukuba ayeke ukuthatha izidakamizwa kanye nodokotela.

Phakathi ukwelashwa imithi "Bonviva" Ukudla lesiguli kufanele kube uvithamini D ne-calcium. Uma ungeke ukwazi fed ngokugcwele futhi qinisekisa ukuthi abasebenzi baphuza calcium ne vitamin D ekudleni, kubalulekile ukwenza amalungiselelo afanele.

Amalungiselelo analogue

Okwamanje, imithi ezivamile - analogue "Bonviva" - ". Ibandronic acid Sandoz" a "Bandronat" futhi Ziyakwazi analogue isithako esebenzayo eyinhloko. Iqembu ngobubanzi okuningi kwemithi eduze "Bonviva" ku lo mshini wezenzo. Lokhu kungabandakanya izidakamizwa ezilandelayo: "Bonefos", "Alental", "Veroklast", "Zoleriks", "Lindron", "Ostealen", "Rizendros", "Foroza" "Fosamax". Ukuze esikhundleni esimisiwe izidakamizwa Analogue "Bonviva" (intengo, ukubuyekezwa umthengi akuzona esanele), kufanele ngaso sonke isikhathi bonana nodokotela wakho noma wemithi.

lebanga lentengo

Naphezu kweqiniso lokuthi "Bonviva" amaphilisi ekhiqizwa yizimboni ngemithamo ezintathu (2.5 mg, 5 mg 150 mg), i-yasakazwa zabathengi isidingo kuyinto ithebhulethi nge umthamo esiphezulu 150 mg. Lokhu umthamo kufanelekile kokuthola (1 ngenyanga), kodwa izidakamizwa akuyona ezishibhile. 1 tablet angathengwa inethiwekhi ekhemisi yemali kuleli uhla ruble 1.650 ukuze 2120. Zonke ezinye sefomu tablet bayindlala kakhulu Ungasebenzisi, ngoba ukuze uwathole Pharmacy kuyinto ngempela eziyinkinga.

Imijovo "Bonviva" futhi wawina idumela emakethe yezemithi ukuthola umthengi. Imijovo umthwalo ngaphezulu isiguli kuka umthamo esibhebheni 150 mg: umjovo i-yinqubo eyaziwayo isikhathi 1 kuya ku-3 izinyanga. Nokho, lolu hlobo lomuthi ukukhululwa izobiza okuningi isamba eningi ukwedlula amaphilisi. Kweyoku-1 ampin umthamo emthanjeni 3 mg izidakamizwa "Bonviva" Inani Pharmacy kungaba isukela 5525 ruble 5950.

umbono umthengi

Naphezu sasivumela okwandile udumo "Bonviva" ukulungiselela (yokusetshenziswa, intengo - kumele wathi, kakhulu - ubufakazi) ukubuyekezwa imithi has a ukuma ezahlukene. Bobabili emihle nemibi. Wathola iqembu elincane ezigulini kusikisela ukuthi usuku olulandelayo emva umjovo ubuhlungu ngokwanele wabonakaliswa ngokucacile: ubuhlungu wonke umzimba, kunciphisa imisipha, emgogodleni bekumatima kuyekela. Abanye babekhathazeke ukuqubuka.

ungezwa ezigulini njalo ngokwanele ukuthi ngemuva kokuthola ukungakhululeki uyakhumbula ipheshana lakhe emathunjini. Nokho, ubuhlungu kuyaqabukela sifinyelela ezinye amagugu ezibucayi ezidinga ukwelashwa okukhethekile ukuze akuqede. Positive umphumela "Bonviva" ivala ukuphendula pheshana emathunjini.

Kukhona okubuyayo, "Bonviva" okuyinto nje uba panacea for the fragility futhi brittleness lamathambo. iziguli eziningi kakhulu uqaphela ushintsho angafani ngcono enkothweni. Abaningi ngacishe ngayeka lingamlimazanga emuva, slouch elincane, babe nekutetsemba kakhulu futhi kulula ukuhamba. Futhi ngisho yalezo ziguli subjectively akukho okushintshile kusukela inhlolovo babeqiniseka ukuthi ohlangene ithambo izicubu.

Enye iziguli wanelisekile kakhulu ukuthatha umbuso izidakamizwa. Naphezu kweqiniso lokuthi "Bonviva" intengo, njengoba besho, ukulunywa, kulula kakhulu - iphilisi elilodwa bese ukhohlwa mayelana nokwelashwa inyanga. I Kungashiwo okufanayo mayelana imijovo (1 njalo ezinyangeni 3). Okubalulekile, ungakhohlwa mayelana nokuthatha umthamo olandelayo.

Ezinye iziguli agxile eqinisweni lokuthi ekuqaleni ukwelashwa imithi "Bonviva" isimo waphawula, elifana nalelo okwenzeka nge Umkhuhlane ukutheleleka. Kodwa-ke sahamba ngokushesha, futhi yini okufanele bayisho, kuqhathaniswa ingozi yokuba kwamathambo, uthi ezinjalo - ubuncane enkingeni.

Ezinye iziguli ngubani ubukeza "Bonviva" Nokho futhi kufanele isimangalo omuhle kuphela ukuthi reception parallel ndawonye nale izidakamizwa, "Calcium D3" kwaba nomphumela omubi ezithweni wokugaya ukudla.

Efingqa

"Bonviva" - umkhiqizo yesimanje futhi ephumelela kakhulu eziklanyelwe ukuvimbela ukukhumuzeka kwamathambo bone ekubhujisweni. Naphezu kamnandi mayelana izidakamizwa "Bonviva" (Umyalelo, intengo zazo ezazibhekwa isibuyekezo) Izibuyekezo kakade ukuthatha leli imithi isiguli, kufanele sikhumbule ukuthi okuwukuphela kwesisekelo emizameni yokwelapha - ukuqondiswa udokotela ukuba khona. Kubalulekile ukuthola udokotela uzothatha ngokukhulu ukucophelela kokuhlaziywa kwamathenda impilo isiguli sakhe futhi kahle ukhethe uhlobo lwemithi nokushintsha kokudla nokufakwa. Kuphela kulesi simo ingozi nemiphumela engathandeki yalawo maphilisi uzobe incishisiwe, kanye umuthi uyophumelela ukuzibonakalisa njengoba kuyithuluzi eliphumelela kakhulu ekwelapheni kwamathambo nokugcina enamandla.