Umuthi 'Artoksan ": yokusetshenziswa, nozakwabo yangempela

Nonsteroidal eqeda ukuvuvukala ejenti zidayisa konke Pharmacy. Nokho, akuzona zonke isiguli uvunyelwe ukusebenzisa ezifana amaphilisi ezinhlungu. Lokhu kungenxa ngokuyinhloko yokuthi banayo inombolo enkulu yemiphumela emibi.

Namuhla sizokutshela ukuthi lena izidakamizwa ngokuthi "Artoksan". Yokusetshenziswa kwaleli thuluzi sizobuye kubhekwe. Futhi kulesi sihloko, uzofunda ukubaluleka izidakamizwa, imiphumela engemihle kanye contraindications.

Ukwakheka, ukuma, incazelo kanye emaphaketheni

Izidakamizwa "Artoksan" itholakale ukudayiselwa ngesimo powder lyophilized, eluhlaza nephuzi. Futhi eziqukethwe isixha amakhadibhodi kuphela njengoba uketshezi kungekho nto enemibala emihle futhi esobala.

Isici esebenzayo ithuluzi izenzo tenoxicam. Ngaphandle-ke, ekulungiseleleni ihlanganisa excipients ezilandelayo: i-sodium hydroxide, mannitol, edetate disodium, ascorbic acid, hydrochloric acid tromethamine.

Ngo ukudayiswa nomuthi enikeziwe in vials (kuphela - e ampoules) kanye amabhokisi ngokulandelana.

Isenzo zomuthi

Kuyini lokhu imithi ngokuthi "Artoksan"? imiyalelo Isicelo ibonisa ukuthi siyanda ngempumelelo non-steroidal ejenti eqeda ukuvuvukala, esesikhundleni analgesic eqinile futhi antipyretic umphumela kancane kancane evelele.

Izakhiwo nomuthi ngenxa okusithiyayo amabili isoforms we cyclooxygenase enzyme. Ngenxa yalokho kuzichaya kuyaphazamiseka arachidonic acid umzimba prostaglandin zamagama ivinjelwe.

izakhiwo eqeda ukuvuvukala we imithi ngenxa nokuncipha capillary permeability, okusithiyayo of synthesis balamuli ukuvuvukala (histamine, prostaglandins, lymphokines, umphelelisi izici futhi bradykinin) kanye kuqiniswa of lysosomal ulwelwesi.

Futhi, ukusetshenziswa kwezidakamizwa olucutshungulwayo kunciphisa inani radicals khulula e focus ukuvuvukala, kuvimbela chemotaxis futhi phagocytosis, kubamba isigaba proliferative ukuvuvukala, kunomphumela chondroprotective futhi kunciphisa okuthunyelwe ukuvuvukala izicubu ukuqina.

Kufanele futhi wazi ukuthi lesi sidakamizwa "Artoksan", analogue zazo ethulwa ngezansi, kunciphisa ubuhlungu maphakathi ukuvuvukala enza thalamic ubuhlungu izikhungo. Futhi, ngemva kokusebenzisa isikhathi eside ke kunomphumela desensitizing.

In izifo rheumatism izidakamizwa kunciphisa ubuhlungu emalungeni, kunciphisa ekuseni yabo ukuqina nokuvuvukala. Ngaphezu kwalokho, kuthuthukisa izici kwandisa nokuhamba apharathasi ligamentous.

I kinetics zomuthi

I nomuthi "Artoksan" (imijovo) has a eside ekuphileni isigamu (cishe 60-75 amahora). Kulula pretty ukuba adabule izithiyo igazi-kwezicubu lingena kahle ku uketshezi lwamalunga.

Ithuluzi libhekene bioavailability okusezingeni eliphezulu (cishe u-100%).

ubufakazi

Yikuphi ephatha yezifo izidakamizwa "Artoksan"? Yokusetshenziswa ukhombise izinkomba ezilandelayo:

• rheumatoid arthritis, ankylosing spondylitis, kanye arthritis gouty;
• Izifo ukuvuvukala futhi esiwohlozayo of the system zemisipha, ephelezelwa ubuhlungu syndrome eqinile;
• osteoarthritis ukhwaliti ubuhlungu emuva;
• polyarthritis nonspecific imvelo samafayela;
• bursitis, tendonitis, myositis futhi periarthritis;
• neuralgia, arthralgia, ischialgia, myalgia futhi lumbago;
• ukusha kanye nokwethuka.

Izimo

Nomuthi "Artoksan", ukubuyekezwa zazo akhayo ngokwezinga elikhulu, is contraindicated ku:

• ukopha emathunjini;
• hypersensitivity kuya tenoxicam, nezinye ama-NSAID;
• izilonda erosive futhi esidalwa yizilonda emathunjini sibe yokusetshenziswa pheshana emathunjini;
• ukhulelwe;
• "Aspirin triad";
• ibele;
• ebuntwaneni;
• ukwehluleka kwezinso;
• iziyaluyalu ukusebenza izinso futhi isibindi;
• ukuhluleka kwenhliziyo;
• izifo igazi.

Izidakamizwa "Artoksan": yokusetshenziswa

Njengoba sihlole izidakamizwa kumele kusetshenziswe? Ngokusho imiyalelo, umuthi kwezokuphatha emthanjeni noma esicutshini. Ngokuvamile, iqondiswa ngendlela umthamo mg 20 kanye ngosuku. Iyasebenza njengoba umthamo nokugcinwa 10 mg zomuthi ngosuku.

Lapho uzwakalise ubuhlungu emizweni nenani lomuthi zingandiswa ukuba 40 mg kanye ngelanga.

Ephambi kwezinduna ukuhlaselwa acute ka gouty sokuqaqamba kwamalunga nomuthi iqondiswa 20 mg kabili ngelanga phakathi nalezo zinsuku ezintathu kuqala bese 20 mg kanye nsuku zonke izinsuku eziyisihlanu.

side effects

Yimiphi imiphumela engadingeki zenzeka ngesikhatsi ukwelashwa nge izidakamizwa "Artoksan"? Imijovo ezibhekwa yithi, kungase kubangele:

• yiSigungu Sikazwelonke: bekhanda nesiyezi;
• Kwesisu: isicanucanu, ukungakhululeki kanye ubuhlungu besisu, ukuvuvukala;
• njengemithi yokungezwani komzimba nokuthile: ukuqubuka, pruritus, erythema, Lyell Syndrome futhi Stevens-Johnson.

Futhi, ukusetshenziswa ithuluzi zingashintsha amagugu laboratory (okuhlushwa ukwanda egazini urea kanye creatinine, kanye lenyuka isibindi transaminase umsebenzi).

izidakamizwa ekuhlanganyeleni

Reception nokubika izindlela ezikhulisa imithelela izidakamizwa lithium futhi anticoagulants. Kule ndaba, kubalulekile ukuqapha prothrombin Inkomba lesiguli.

Uma usebenzisa lokhu imithi nge isisu kumele ibhekelele izinto eziphathelene Cishe ukubambezeleka sodium ne amanzi emzimbeni wesiguli.

izincomo ezithile

Phakathi isikhathi eside ukusetshenziswa "Artoksana" kuyadingeka ukulawula umsebenzi isibindi nezinso isiguli.

Phakathi ukuhlinzwa kufanele uqaphele ukuthi lokhu umuthi yelule ukopha isikhathi.

Kudingeka ukunakekela okukhethekile kuyindlela yokuthola abantu enqunyiwe ngaphansi kweminyaka engu-18 ngenxa yokungabikhona kolwazi olwanele mayelana nokusebenzisa kwabo tenoxicam.

Izidakamizwa "Artoksan": intengo kanye analogue

Analogue of nomuthi zibhekwa ngezindlela ezilandelayo: ". Diclofenac sodium" "Oksiten", "Ketorolac", "Aspikard" "ketoprofen", acetylsalicylic acid, "Indomethacin"

Intengo yaleli izidakamizwa akusilo eliphezulu kakhulu. Kuyinto ruble 60-80.

Uphenyo imithi

Njengoba kushiwo ngenhla, ama-NSAID athandwa kakhulu phakathi abantu baphathwa izifo of the system zemisipha. "Artoksan" Isidakamizwa ephumelela kunazo. Kwasheshe aqede ubuhlungu, kususa ukuvuvukala futhi edema.

Njenganoma iyiphi i-ejenti non-steroidal, le nomuthi sivame ukukhuthaza izinhlelo okuvela ohlangothini ukusabela, ikakhulukazi kusukela ipheshana wokugaya ukudla. Ngakho-ke, zisebenzise lokhu izidakamizwa kufanele kube kuphela izinkomba ekhethekile.