Ukulungiselela 'Pantothenate calcium': izici nokusebenzisa kwezokwelapha

I-Pantothenic acid (ifomu lezidakamizwa elithi "Pantothenate calcium") liyingxenye yeqembu le-vitamin B. Liyi-oily, i-olymatic actif liquide ehlakazeka kahle emanzini, ebola kalula ngaphansi kwefuthe lokushisa okuphezulu, ama-acids nama-alkali.

I-Pantothenic acid iyatholakala ekudleni futhi ihlanganiswa yi-microflora yamathumbu (Escherichia). Ngemva kokumunca, kungena egazini bese kusabalalisa kuzo zonke izitho nezicubu, ezifakwe esibindi, ngokuyinxenye ku-myocardium, izinso kanye nemisipha yamathambo. Emzimbeni, i-asidi ihlotshaniswa kakhulu namaprotheni futhi iyingxenye yeCoA (coenzyme A). Imikhiqizo yokuqothula yezidakamizwa "i-calcium pantothenate" idonswa emzimbeni ngomchamo kanye namanzi. Kufanele kuthiwe ukuthi inani le-pantothenic acid elikhishwe lihlale likhulu kunelokho okufakwe ukudla. Lokhu kungenxa yokuhlanganiswa kwamagciwane.

I-Pantothenic acid iyingxenye ebalulekile ye-CoA, equkethe izingxenye ezintathu: i-resio ye-thiolamine, i-pantothenic acid, i-3-phospho-5adenosine-5-diphosphate. I-CoA iyisixhumanisi esiyisihluthulelo ku-metabolism, iyingxenye ekusebenzeni komjikelezo we-Krebs, ekufakweni kwezinto eziphilayo kanye ne-oxidation ye-carbohydrate, lipids, ukwakheka kwe-glucosamine, i-acetylcholine, i-hippuric acid, i-porphyrins, njll.

Ukulungiswa kwemithi "I-pantothenate ye-calcium" - i-powder kancane ephuzi noma emhlophe, enomuncu ukunambitha, ingenasiphelo, ikwazi ukungena kalula emanzini. Izixazululo ezinomsoco zinamandla kakhulu, kodwa, uma zivezwa kuma-acids nama-alkali, ziyashesha ngokushesha. I-agent yezokwelapha itholakale ngendlela yamathebulethi, i-powder kanye nezixazululo ku-ampoules.

Ukulungiselela "i-Pantothenate calcium" kubonisa umphumela wezokwelapha emva kokuba i-pantothenic acid iphenduka i-coenzyme A, ehlinzeka nge-beta-oxidation, i-synthesis of fatty acids, i-decarboxylation ye-oxidative kanye nokuguqulwa kwe-pyruvic ne-ketoglutaric acid ku-acetylcoenzyme. Kuyasiza ukumuncwa kwe-glucose emathunjini, kwandisa izinga le-glycogen esibindi, kuvumela isimo se-hormonal senyama, ikakhulukazi ngesikhathi sokukhulelwa.

Ngokuntuleka kwe-asidi pantothenic emzimbeni, umsebenzi we-hormonal we-pituitary, i-adrenal kanye ne-pancreas inqatshelwe. Izinga lama-hormone e-steroid liyancipha emahlathini amancane, okuhlinzekela ukuhlunga izinwele kanye nesikhumba. Ukuphazamiseka kwe-metabolism kubangela ukubonakala kwe-dermatitis, ukuchithwa kwesikhumba. Izinguquko ze-Dystrophic emathisini adrenal and nerve ziyabonakala. Futhi, ukuhlanganiswa kwezinyathelo kungaphazanyiswa , izinso, inhliziyo, isisu kanye nezifo zesisu zingagxiliswa. Izimbangela ze-hypovitaminosis eyinhloko ayinani elanele lamavithamini ekudleni, izifo zesisu, kanye nokusetshenziswa isikhathi eside kwama-antibacterial agents (sulfonamides, antibiotics).

Izimpawu ezisemtholampilo zokuntuleka kwe-asipho pantothenic emzimbeni kukhona ukucindezeleka, ukukhathala, ukukhathala, ukuphazamiseka kokulala, ukuphathwa ikhanda kanye nezinhlungu zomzimba, isicanucanu, isifo sohudo, i- hypermia yonyawo, isilonda se-duodenal. Ukuntuleka kwaleli vithamini kunciphisa ukumelana nokuzivikela komzimba. Ngalesi sizinda, izifo zokuphefumula zivame ukuvela.

Ukuze ulawule izinqubo zokuxilonga umzimba ngokuvamile odokotela banquma ukuthi umuthi "Pantothenate calcium". Le mithi ithathwa ngokuthi i-polyneuritis, i-paresthesia, i-neuralgia, i-bronchitis, i-eczema, i-dermatitis, i-burns, i-trophic ulcers, i-toxicosis yabesifazane abakhulelwe, isifo sofuba, i-hypothyroidism, i-pancreatitis, i-gastroduodenitis, njll. Umuthi "Pantothenate calcium" ubekezelela kahle umzimba. Ngokuphathwa kwe-enteral, izenzakalo zengcindezi zingenzeka , nge-parenteral (injection yangaphakathi) - ubuhlungu.

Ukwehla kwe-calcium (i-hypercalcemia) ingenzeka ngenxa yokungasebenzi kwemisipha ye-endocrine (i-parathyroid gland). I-Hypercalcemia ibhalwa kubantu asebekhulile. Umtholampilo we-hypercalcemia ungazibonakalisa ngesimo sobuthakathaka jikelele, ukulahlekelwa ukudla, ngezinye izikhathi kukhona ukuxubana nokuqokwa.