Tablets "Bergolak": ukubuyekezwa, imiyalelo, amanani

"Bergolak" - umuthi okuqondene agonists Dopamine yokwamukela futhi ehlanganisa cabergoline, oluyisisekelo izidakamizwa izidakamizwa ethathwe ergoline. "Bergolak" lilidlula kuthinta inqubo prolactin. Ngenxa yalokho i-reception yayo ezingeni igazi prolactin encishisiwe, kukhona ukubuyiselwa wenzalo nokuqedwa izifo kokuya esikhathini. Owenza madoda izidakamizwa kunciphisa kobukhulu ukubonakaliswa ezithile hyperprolactinemia.

Pharmacokinetics

Kukhona ukumuncwa okuhle nokusakazwa umfaniswano ngemva kokusebenzisa "Bergolak". Izibuyekezo ukukhombisa ukuthi lezi izinkomba ukudla akunamthelela. Ngokwe-mfundo, emakamu eliphezulu kakhulu okwamanje izidakamizwa e-plasma yegazi ngemuva kokuthi i isilinganiso 2.5 amahora, kuyilapho ingxenye core lihlotshaniswa amaprotheni alo ngu 41-42%.

Emzimbeni kukhona umzimba esebenzayo "Bergolaka". Kwakheka ngenxa yale nqubo ketshezi etholakala emathunjini (mayelana 72%) kanye nezinso (cishe 18%). Ukwakheka umchamo likhona 2-3% isithako esebenzayo ngendlela zinjalo.

izinkomba

Umuthi ezinqunyiwe pituitary izimila kanye nenzalo zesifazane. kahle eNkulu umjikelezo wokuya esikhathini emva kokwelashwa ukuboniswa kwesokunxele "Bergolak" kusho izilinganiso. Ukupheliswa lactation ngenxa yokwamukela ukulungiselela ezimbi zingenza nokuhlukileko. Isidingo ukucindezelwa yale nqubo, zingaba khona ngemva isisu nokubeletha. Lactation bengayi kuphela ukucindezela, kodwa futhi ukuvimbela.

"Bergolak" aqede thuthuva okubangelwa hyperprolactinemia. Izinkomba ngoba ukusetshenziswa nomuthi kuthiwa prolactin secreting pituitary adenomas, hyperprolactinaemia idiopathic. Ngokusekelwe ukulungiselela "Bergolak" angase abe abantu nokwelashwa kweziguli ngalesi sifo, okuthiwa "ezingenalutho sella syndrome" futhi hyperprolactinemia iyakhula.

Kudinga ukunakekelwa okukhethekile ngesikhatsi ukwelashwa nengane esindayo futhi ibele. Reception kusho iziguli ezinokuphazamiseka kwesibindi kufanele kwenziwe ngaphansi kweso lwezokwelapha.

Izimo

Imiyalelo owawudalwe "Bergolak" kusho izimpendulo lodokotela ibonisa Izimo:

• Hypersensitivity kuya izingxenye;
• yobudala Wezingane (eneminyaka engaphansi kwengu 16);
• ukumuncwa enganele glucose ne-galactose;
• lezinceku galactose ukungabekezelelani amafomu ezingajwayelekile;
• yokuntuleka azalwa naso we lactase;
• sengqondo ezivukayo emva kokubeletha;
• ezinkingeni, iziyaluyalu inhliziyo ngenxa izinguquko fibrotic emzimbeni, t h umlando ..;
• kokuphakama eziphikelelayo wegazi, ongalawuleki.

Ekwelapheni imithi abadala kufanele kuthathwe ngokuqapha. Kuyefana nasendleleni iziguli esibindini onesifo.

Ukusebenzisa nomuthi, umthamo

Njengoba kwesokunxele ngemuva kokuthola izindlela "Bergolak" izilinganiso, lactation ingavinjelwa noma aphazamisekile. Kuye umthamo okuhloswe yenkinga:

• ekuthuthukiseni lactation - 1 mg izidakamizwa, elihambisana izibhebhe ezimbili iyoshiswa ngesikhathi esisodwa, esezele ingane (ngosuku olulandelayo);
• ngemuva ukuthuthukiswa yayo - 0.25 mg, okulingana isigamu ithebhulethi ukuze uyiswe izinsuku ezimbili nge ngezikhawu angu-12.

Uma kunezinye izinkomba Odokotela bavame linqume yeziguli Bergolak "endaweni umthamo 0.5-1 mg izidakamizwa kanye noma kabili ngesonto. Umkhawulo izinga ovumelekile Yisonto 4.5 mg izidakamizwa. Leli akulona ushintsho abukhali at umthamo esiphezulu, kancane kancane kuphela ekuzikhuliseni ngu 0.5 mg njalo ngenyanga, uma isidingo sikhona. ukusetshenziswa Imithi ngaphakathi nge ukudla.

Iziguli sebenzisa "izimpendulo Bergolak 'ukwehlisa amazinga prolactin e hyperprolactinemia ushiye ikakhulukazi omuhle. Thuthuva kubangelwa le nqubo, iphathwa ngokusebenzisa i umthamo kokuqala seviki 0.5 mg. A ngokuhlukana we ezimbili esenikwe 0.25 mg reception izindlela. Kulokhu ukulungiswa ingasetshenziswa kabili ngesonto.

abesifazane lactating ikakhulu nomuthi iqondiswa ukuze ngesikhathi esisodwa emzimbeni uthola ayibi ngaphezu kuka-0.25 mg izidakamizwa. Ngakho inani kungenzeka ukuqeda kungenzeka ohlangothini ukusabela.

Umthamo zokwelapha, zenzelwe ukusetshenziswa ngeviki, ngokuvamile akuyona ezingaphezu kuka 2 mg. Nakuba zonke ngazinye futhi isiguli ngasinye udokotela ukhetha umuntu kukho ukwelashwa.

Abesifazane abakhipha ngesikhathi sokukhulelwa wasebenzisa "Bergolak" Ukubuyekezwa kwesokunxele ngokuqukethwe ulwazi isidingo ukusebenzisa ngokucophelela izidakamizwa. Ngezikhathi ezinjalo, impilo sokusebenza kwawo kwenziwe ngaphansi kweso lwezokwelapha njalo futhi kuphela ngemithamo ezinconyiwe ke. Naphezu kweqiniso lokuthi abesifazane abakhulelwe zisebenzisa iphilisi is hhayi Kunconywa ezimweni lapho izinzuzo emzimbeni kamama kakhulu lidlula izingozi ezingase zibe khona ezingenzeka embungwini, kwamukelekile. Ukuncelisa ngenkathi "Bergolakom" Ukwelapha imisiwe.

side effects

ukusabela engathandeki kungase kube ezahlukene, futhi ngobubi bawo kungenzeka futhi ziyahlukahluka. Ezimweni eziningi, zonke izimpawu ezingemnandi zinyamalale ku zabo izinsuku siqu ngaphakathi 14 yokwelashwa noma emva kwesikhathi esithize ngemva Ukuyeka izidakamizwa.

Ukwahlulela iqiniso ukuthi washiya ngenxa imithi yokwelapha "Bergolak" izimpendulo ukhombise Amathuba okuvela isiyezi, ukozela futhi lobu buthaka bungase ngezinye izikhathi sibe sibi impilo jikelele.

Kunengozi komzimba ezithinta isikhumba. Okungenzeka isikhumba ugodo ngenxa zizwa amakhaza. Kungafaka ushintsho ukusebenza emathunjini, isib, ukuqunjelwa kanye nesicanucanu. Phakathi kwezinye side effects - acinene, ngomlomo mucosal desiccation.

izidakamizwa ekuhlanganyeleni

Sithola ukuthi ungasebenzisa i-kuhlanganiswe ukuphathwa amaphilisi "Bergolak". Uphenyo odokotela ukukhombisa ukuthi izidakamizwa akufanele isetshenziswe ngokuhlanganyela ergot alkaloids, nemikhiqizo yabo ngesikhathi yokwelapha isikhathi eside.

Khumbula ukuthi abanye abantu abamelene nani ka Dopamine receptor kubathinta kungathinta isinyathelo wayenethonya cabergoline futhi macrolides - ayinyuse we ketshezi esebenzayo "Bergolak" izidakamizwa egazini. Utshwala kwenza izidakamizwa ayisasebenzi.

Imithi okukhomba zokunciphisa blood pressure ngesikhathi yokwelapha kusetshenziswe ngokuqapha.

Izixwayiso

Uma uhlela ukuba akhulelwe, ukuthi ilungile kuphela emva kwesikhathi esithize emva kokuphothulwa yokwelapha, ngokuvamile ngenyanga. "Bergolak" kuphela ngemva Ukutadisha ngokucophelela pituitary. Phakathi ukwelashwa kufanele uqashelwe njalonjalo isimo umzimba.

Nakuba ikhambi is hhayi Kunconywa ukuba ukushayela imoto nezinye izimoto, ukwenza imisebenzi ezidinga impendulo esheshayo nokunakekela ngcono. Kubalulekile ukulandela zonke izincomo udokotela.

Izindleko, ukubuyekezwa

Kubantu abaningi abahlela ukuthatha "Bergolak", intengo, izibuyekezo - kuba njalo ulwazi equkethe izinto eziningi ewusizo, ikuvumela ukuba wazi kusengaphambili izindleko zomuthi, ikakhulukazi ekwelapheni kanye kungenzeka ukusabela ezingezinhle olutholwa iziguli ngesikhathi yokwelapha, ukuhlola ukusebenza yayo .

izindleko cishe izibhebhe (2 PC. 0.5 mg) kuyinto 235-260 deda. Mayelana nokusetshenziswa "Bergolaka" ukumisa lactation noma ukuyivimbela, nahlulele by ukubuyekezwa, lemisebenti imithi njalo ukubhekana kahle. Kepha iningi amathuluzi ngesikhathi gipoprolaktinemii ukugubha ekuzuzweni kwemiPhumela nomphumela ofiselekayo. Nokho, kukhona ingozi izigameko ezingezinhle ezavela kusho ukuthi abanye isaziso lapho besanda kuqala ukwelashwa.

Abaningi ejabulisa isinyathelo ngokushesha futhi eziphansi zomuthi iqhathaniswa nezinye izidakamizwa ezifanayo. Ngezinye izikhathi imiphumela emibi waphawula ukuqunjelwa, ukozela futhi ikhanda kancane.