Lysozyme - kuyini? Ukulungiselela "Lizotzim": imiyalo yokusetshenziswa, intengo

Lysozyme - kuyini? Sizophendula lo mbuzo onzima wezokwelapha kulesi sihloko esithunyelwe. Futhi uzothola ukuthi yini le nqubo esetshenzisiwe, kungakhathaliseki ukuthi inokuphikisana nokuthi kubaluleke kangakanani.

Ukwakhiwa, ifomu, incazelo

Ngakho, i-lysozyme. Kuyini? Ngokusho kochwepheshe, i-lysozyme ibizwa ngokuthi i-enzyme ekhethekile noma i-antibacterial agent, okuyi-protein-like (etholakala kumaprotheni amaqanda ezinkukhu). Isisindo sayo samangqamuzana amakhilogremu angu-15,000 amagremu ngayinye.

Ukwakhiwa kwesidakamizwa segama elifanayo kuhlanganisa into esebenzayo njenge lysozyme hydrochloride.

Iyiphi ifomu ehambelana nesidakamizwa "i-Lizotzim"? Imiyalo yokusetshenziswa iqinisekisa ukuthi le mithi itholakala ngesimo se-lyophilizate oyinyumba noma i-powder ehlose ukulungiselela ukumiswa. Unesakhiwo sama-amorphous, umbala omhlophe kanye nephunga elimnandi likaviniga.

Isidakamizwa esibuzwayo sihlanganiswe emigodini engu-1, 0.15 noma 0.05 amagremu.

Izakhiwo zemithi yezidakamizwa

Isidakamizwa "i-Lizotzim", intengo yayo ekhonjisiwe ngezansi, inezinto zokulwa namagciwane, anti-inflammatory and mucolytic. Izici ezinjalo zokwelapha zalesi sidakamizwa zikhona ngokuphelele ngenxa yokwakhiwa kwayo.

Isidakamizwa "Lizotzim" - siyini? Into esebenzayo yalesi sidakamizwa ibhekiselwa enzyme ethile yeklasi le-hydrolase. Ikwazi ukubhubhisa izingqamuzana zamangqamuzana amabhaktheriya. Inqubo enjalo yenziwa yi-hydrolysis ye-enreme ye-murein noma ye-peptidoglycan, eyingxenye yezindonga zamaselula ezincane. Inani elikhulu kunazo zonke le-murein liqukethwe emaqenjini amabhaktheriya anesigamu.

Futhi into ngokwayo i-lysozyme - iyini futhi iqukethe kuphi? I-enzyme enjalo itholakale ezinhlobonhlobo zezinyembezi, ubisi lwebele, umlenze, esitebeleni nesibindi, kanye ne-mucosa yepheshana lezinsipho kanye ne-nasopharynx.

I-Lysozyme ematheni inendima yokuzivikela. It kuvimbela ingress of ejensi ehlukahlukene eziyingozi emzimbeni. Le ndawo iyimpawu yamanye amabhungane amancane, lapho i-enzyme iqukethe khona.

Umuntu akakwazi kodwa uqaphele iqiniso lokuthi ukuxilongwa kwe-lysozyme kuphezulu ebisi lwebele. Kusukela isikhathi, inani lalo liye landa, lafinyelela ezinyangeni zalo eziyisithupha emva kokubeletha.

Kwenzekani?

I-lysozyme ikhiqiza ini? Imfundo ithi leyo enzyme itholakala kumaqanda amaprotheni (inkukhu). Iyingcosana ngobukhulu futhi iqukethe kuphela ama-amino acid angu-129 kuphela.

Ngaphandle kwezinto eziphikisana ne-antibacterial, le-agent ivuselela amandla asebenzayo omzimba, futhi iphinde ibenze i-phlegm uma ikhwehlela futhi inomthelela wokunciphisa okulinganiselwe.

Umuntu akanakusiza ukusho ukuthi lesi sidakamizwa sithuthukisa imiphumela yama-antibiotic ahlukahlukene. Akuyona into enobuthi futhi kuvame ukusetshenziswa njengengxenye yokwelashwa okuyinkimbinkimbi.

Ngemuva kokungena emzimbeni, lo muthi ususelwe kahle emgodini wokugaya. Ifinyelela ekuhlungeni okuphezulu ngemva kwamahora angu-1.5. Lesi sici singakwazi ukuqoqa ngobuningi emangqamuzaneni amancane.

Izinkomba

Iziphi izifo ozisebenzisa ngayo izidakamizwa "Lizotzim"? Ukusetshenziswa kwale mithi kuboniswa nge-pneumonia nezifo ze-bronchopulmonary, kanye nokuthi:

• I-hepatitis engapheli;
• Izilonda zesikhumba ezikhuthazayo;
• Conjunctivitis;
• Izifo ze-ENT izitho;
• Stomatitis;
• Ukushisa, ama-frostbite, ama-bedsores nokuguguleka kwe-cornea yeso;
• I-blepharokeratitis ye-allergen.

Kumele kuqashelwe ukuthi le mpikiso ivame ukushiwo ekwelapheni izifo ezihlukahlukene ezithathelwanayo, ezibangela ukugula, nezifo. Ngokuvamile lisetshenziswa kanye nama-antibiotics.

Ukungafani

Ngenxa yokubekezela okuhle kwezinto ezisebenzayo zalesi sidakamizwa, kanye nesifo sofuba esincane, asikho ukuphikisana. Nokho, udokotela kuphela okufanele anikeze ikhambi elinjalo.

Ukulungiselela uLizzym: imiyalelo yokusetshenziswa

Ngokweziqondiso, imithi esetshenziselwa umbuzo isetshenziselwa phezulu, kanye ne-inhalation. Ezimweni ezingavamile, ingasetshenziselwa umjovo we-intramuscular.

Ngaphambi kokusebenzisa le mithi, kufanele ihlakazwe ku-0.25% i-novocaine noma isisombululo (isotonic) se-chloride ye-sodium.

Endaweni yile mithi isetshenziswe ngendlela yokufaka umkhuba ophthalmic. Ifakwa esweni kathathu ngosuku ngezinsuku ezingu-3-6.

Lapho ukwelashwa izifo ze-ENT noma i-pneumonia, imithi isetshenziselwa uhlobo lwe-inhalation. Ngesinye isikhathi, sebenzisa cishe u-2-10 ml wezidakamizwa. Isikhathi sokwelashwa nalesi sidakamizwa siyizinsuku ezingu-5-14.

Nge-frostbite nokushisa, kanye nokwelapha amanxeba ahlanzekile, lo muthi usetshenziswa ngendlela yama-appliques. Esikhathini sesisombululo se-0.05%, indwangu oyinyumba ifakwe futhi isetshenziswe endaweni ethintekile.

Ngokuqondene nokujova kwe-intramuscular, zikhiqizwa kathathu ngosuku ngo-100-150 mg ngosuku. Ubude bokwelashwa okunjalo yizinsuku ezingu-7-10. Uma kudingekile, inkambo ingadluliselwa enyangeni eyodwa. Kulokhu, ukuqapha okuqhubekayo kwegazi kubalulekile.

Kumele futhi kuqaphele ukuthi i-agent engumbuzo ingasetshenziswa ngemva kwe-anesthesia, ngesikhathi ilungiselelo lesiguli sokuhlinzwa. Ihlanganiswe amathoni, ama-tubes wokufakelwa kanye nama-bandage.

Izenzakalo ezimbi

Ngokuphathelene nokusetshenziswa kwalesi sidakamizwa, ukusabela kwe-hypersensitivity akuvamile kakhulu esigulini.

Njengoba ukuphathwa kwe-intramuscular okwesikhashana isikhathi eside, lesi sifo senzeke.

Izindleko zezidakamizwa nokubuyekezwa ngakho

Kubiza malini umuthi "Lizotzim"? Intengo yalesi sidakamizwa kumaketanga ahlukene ekhemisi angahluka. Ngokwesilinganiso, izindleko zayo zingama-ruble angu-280-350.

Kukhona izibuyekezo ezimbalwa kakhulu kulo muthi. Futhi lezo ezitholakalayo ziningi kakhulu. Iziguli ziphikisana ngokuthi umuthi onjalo unomphumela omuhle we-mucolytic ne-anti-inflammatory. Futhi, kuvame ukusetshenziselwa ukushisa okuhlukahlukene, amanxeba ahlanzekile nezinye izinto.

Ngokuphathelene nokusabela okubi, ngakho-ke ngokumelene nesizinda sokusebenzisa umuthi onjalo, cishe ababonisi. Ngakho-ke, iziguli eziningi zinelisekile kakhulu ngemiphumela yokusetshenziswa kwalolu remedy.