"Lasix" e ampoules: yokusetshenziswa, umthamo

Yiziphi yokuhlambulula isisu? It izidakamizwa kokuba ezahlukene izakhiwo zamakhemikhali, zivimbela reabsorption usawoti namanzi ku tubules kwezinso, kanye ukwandisa excretion zabo umchamo. Ngaphezu kwalokho, leyo mithi ukwandisa umkhiqizo umchamo, ukunciphisa okuqukethwe amanzi e izimbotshana serous nezinye izicubu.

Indlela ethandwa kakhulu buyisidakamizwa isisu "Lasix" (ampoules). Umthamo zomuthi, iziqondiso zalo nokubonakaliswa zichaziwe ngezansi.

Ifomu zomuthi, kwikhava yawo, ukwakheka

Yikuphi izingxenye iqukethe imithi "Lasix" (e ampoules)? Yokusetshenziswa uthi ketshezi eyisisekelo yaleli lokulungiselela furosemide. Futhi, kuhlanganisa i-sodium chloride, amanzi umjovo kanye sodium hydroxide.

Lesi sidakamizwa is imakethwa njengekhambi ekuntulekeni w / o noma w / w yokuphathwa. Kuyinto esobala futhi ayinaso umbala.

It sakha lolu hlelo lomthetho ejenti e amnyama ingilazi ampoules iphutha iphuzu, okuyinto Agcwele kuhlaka ingqamuzana plastic.

mshini wezenzo

Kanjani lesi sidakamizwa "Lasix" (e ampoules)? Yokusetshenziswa (lokhu ejenti intramuscularly kufanele sinikezwe kuphela izibhedlela futhi ezimweni ezikhethekile) lithi okusheshayo esebenza isisu sulfonamide esuselwe.

nomuthi Active uyakwazi ivimbela uhlelo ezokuthutha potassium ion, sodium ne-chlorine emnyangweni iluphu enkulu Henle. Yingakho isinyathelo salureticheskim uthe izidakamizwa kuxhomeke ukufika kwalo kule tubules kwezinso.

izakhiwo isisu nokubika izindlela exhunywe kwi-nqubo ukucindezelwa sodium chloride reabsorption e ingxenye wathi (iluphu of Henle). Njengoba imiphumela yesibili, abasolwa zihlanganisa uphakamise izwi umchamo kanye potassium uketshezi kule tubule distal. Futhi ngesikhathi esifanayo, yandisa excretion calcium ne-magnesium ion.

ekuphathweni okuphindiwe kwe- izidakamizwa akusenzi umsebenzi wayo isisu. Lokhu kungenxa yokuthi i-izidakamizwa okukhulunywa uyakwazi uphazamisa impendulo glomerular-ijabulise.

Asinakusho ukuthi "Lasix" isixazululo kubangela ukushukuma (umthamo-kuncike) kohlelo renin-angiotensin-aldosterone.

Izici izidakamizwa

Yiziphi izinto ezinganembile isici "Lasix" izidakamizwa (ampoules)? Yokusetshenziswa okufunwayo senhliziyo umuthi kunciphisa umthwalo futhi umfutho imithambo (yamaphaphu) kanye nokugcwaliswa i-ventricle engakwesobunxele. Ngaphezu kwalokho, lokhu izidakamizwa kunomphumela hypotensive ukuthi kubangelwa ukuncipha wegazi ivolumu (afundwa), ukwandisa sodium excretion bese wehlise ezicutshini ukusabela (bushelelezi) ku semithambo vasoconstrictor imiphumela.

Dose ancike natriuresis futhi diuresis abona othile ewunikela ngesikhathi ngokuthatha izidakamizwa ngesikhathi umthamo 10-100 mg. Ngemva ithonya emthanjeni 20 mg umphumela isisu waphawula ngemva kwehora ¼ futhi yaqhubeka imizuzu engu-180.

ukumnika ukuphatha isikhathi eside ejenti kalula kakhulu kunezimoto ezivamile bolus okuphindaphindiwe. Kufanele kuphawulwe ukuthi imithi ngokweqile imithamo abalulekile ukwanda umphumela iziguli is hhayi waphawula.

izakhiwo pharmacokinetic

Yini imingcele kinetic esivela izidakamizwa "Lasix" (e ampoules)? Yokusetshenziswa ubonisa ukuthi ivolumu ukusatshalaliswa asebenzayo izidakamizwa lokulungiselela 0.1-0.2 amalitha per 1 kg isisindo nesineke.

Furosemide kahle sibopha ukuthi amaprotheni excreted ingashintshiwe nge uketshezi kule tubule proximal.

Isikhumulo isigamu-ukuphila zomuthi emva ukumnika emthanjeni cishe elilodwa nesigamu. Isakhi esiyinhloko zomuthi is excreted ku ubisi lwebele futhi lingena isithiyo esinomhlapho.

Izinkomba ukusetshenziswa yesixazululo

Yikuphi izifo batuse imijovo "Lasix"? Yokusetshenziswa (ampoules / m / e) uthi mithi izinkomba zithi lokhu okulandelayo:

• syndrome edematous kwenhliziyo ukwehluleka bemvelo ezingamahlalakhona;
• syndrome ne edema kwezinso ukwehluleka ezingamahlalakhona uhlobo;
• syndrome edematous of ukwehluleka oyingozi inhliziyo uhlamvu;
• ukwehluleka oyingozi so-renal, kufaka phakathi ukusha nokukhulelwa (ukuze ukusekela excretion uketshezi);
• syndrome edematous bephethwe izifo ezihlukahlukene isibindi (njengendlela yokwelapha aphelele kanye aldosterone abamelene);
• syndrome edematous nge syndrome nephrotic (ekwelapheni lesi sifo ecashile);
• ikhanda nobuchopho edema;
• Ephoqelekile diuresis ukwesekwa ngesikhathi ubuthi chemical (ngamanye amazwi, Zezakhi namuhla excreted ngu izinso ngefomu akushintshiwe);
• Inkinga abanomfutho wegazi ophakeme.

Ukuzithiba ukwethulwa ikhambi

Kwezinye izimo, awukwazi ukungena isixazululo "Lasix" (e ampoules)? Yokusetshenziswa (izingane ukusetshenziswa kwaleli thuluzi kucociswana ngokuhlukile) uthi izidakamizwa akufanele isetshenziswe:

• hypokalemia ezinzima;
• ukwehluleka kwezinso (kufaka phakathi anuria);
• hyponatremia ezinzima;
• precoma hepatic futhi equlekile;
• hypovolemia (umfutho ophansi wegazi noma ngaphandle) noma ukuphelelwa amanzi emzimbeni;
• ukhulelwe;
• abukhali uzwakalise ukwephulwa outflow umchamo evela kunoma yimuphi umthombo (kuhlanganise izilonda unilateral ngomgudu womchamo);
• ibele;
• Hypersensitivity ukuze izithako main;
• uma iguliswa sulfonamides.

Ukusebenzisa izidakamizwa ngokuqapha

Kwezinye izimo ngokucophelela okukhulu kumele kusetshenziswe izidakamizwa "Lasix" (amaphilisi)? Yokusetshenziswa uthi abaphathi enjalo zomuthi kufanele ibe:

• uthi okuyiwona ngokweqile ukwehlisa wegazi kuyingozi (isib izilonda stenotic kwemithambo yegazi yenhliziyo noma i-cerebral);
• hypotension;
• sifo;
• noma manifest sikashukela esicashile;
• acute isilethikusebenza (kuhlanganise kwengozi ukushaqeka cardiogenic)
• syndrome hepatorenal;
• omzimba izicubu erythematosus;
• kahle outflow urinary (wendlala indlala Hyperplasia, hydronephrosis, ukuvaleka we urethra);
• hypoproteinemia;
• ukulahlekelwa kukuzwa;
• sohudo pancreatitis;
• fibrillation ventricular;
• e ababelethwa kungakafiki isikhathi.

Izidakamizwa "Lasix" e ampoules: yokusetshenziswa

A kadokotela ngenxa yezidakamizwa ngokuhambisana lwemithi abakhethiwe kufanele ubeke kuphela uchwepheshe abanolwazi. Ngo kuqokwa izidakamizwa umthamo ephansi kumele kusetshenziswe, okuyizinto anele ukufeza nomphumela ofiselekayo.

I nomuthi iqondiswa intramuscularly kuphela ezimweni ezingavamile. Ngokuvamile, it is wathela ngemithambo yegazi (kancane 4mg ngomzuzu).

kumele kusetshenziswe kangakanani "Lasix" e ampoules ikhambi? Isikali lokhu ejenti incike ubufakazi.

• syndrome Edematous yinhliziyo bemvelo ezingamahlalakhona.

Umthamo kokuqala lalesi sifo kufanele kube 20-80 mg ngosuku. Njengomthetho, it is akhethiwe ngokuvumelana impendulo isisu. Nale uphethwe umthamo nsuku zonke zomuthi uhlukaniswe kathathu.

• syndrome Edematous ukuhluleka inhliziyo oyingozi.

Umthamo kokuqala kulesi simo kuyinto 20-40 mg. Uma kudingeka, kungase ukulungiswa.

• syndrome Edematous okungamahlala ukwehluleka kwezinso.

Iziguli ezinjalo zidinga Ukukhetha umthamo ngokucophelela. It kwandisa kancane kancane, ukuze ukulahlekelwa uketshezi kwenzeka kancane kancane.

• Acute kwezinso ukwehluleka uhlobo (ukusekela excretion uketshezi).

Ngaphambi kokuqala ukwelashwa kufanele bungaveli hypotension futhi hypovolemia, kanye kokunikezwa kwe-acid-base futhi isimo electrolyte. Kokuqala Isikali emthanjeni ngesikhathi leso sifo 40 mg.

• Puffiness yalesi sifo nephrotic.

Kuleli zinga, umthamo kokuqala izidakamizwa izinqolobane 20-40 mg ngosuku. Ngokuvamile, it is abakhethiwe ngesisekelo impendulo isisu.

• Syndrome zingavuvukalanga izifo zesibindi.

Kulokhu, lesi sidakamizwa unikezwa njengoba uhlobo adjunct ekuphatheni aldosterone abantu abamelene nani.

• ubuchopho edema, crisis abanomfutho wegazi ophakeme.

Njengoba yezifo ikhambi elinjalo kuyinto esizosingathwa "Lasix" (ampoules)? Yokusetshenziswa uthi umthamo kokuqala nomuthi wathi lapho izimo kufanele kube 20-40 mg (nge bolus ngomjovo). Kuye umphumela umthamo kungase kushintshwe.

• Ukusekela of diuresis ngenkani e ubuthi zamakhemikhali.

Lokhu nomuthi iqondiswa emva ukumnika emthanjeni of electrolyte izixazululo. Umthamo kokuqala kulokhu 20-40 mg. Phakathi ukwelashwa kubalulekile ukulawula futhi ubuyisele uketshezi alahlekile.

isinyathelo uhlangothi

Ingabe imiphumela emibi ikhambi "Lasix" (e ampoules)? Yokusetshenziswa ngokuvumelana miphumela elandelayo uhlangothi:

• chloropenia, hyponatremia, alkalosis umzimba, hypomagnesemia, hypokalemia, hypercalcemia;
• amanzi emzimbeni, hypovolemia;
• kunciphisa umfutho wegazi, uzizwa yokucindezelwa ekhanda, isiyezi, ukuphazamiseka visual, ikhanda, tachycardia, ukozela, nciphisa, ubuthakathaka, nomlomo owomile;
• amazinga triglyceride cholesterol, futhi amazinga egazi urea kanye creatinine owandiswayo;
• kahle glucose ukubekezelelana, nephritis interstitial;
• isicanucanu, paresthesias, ukuhlanza, uhudo, cholestasis intrahepatic, pancreatitis acute, nephrocalcinosis e preterm izingane;
• ukulahlekelwa kukuzwa, ukuqubuka, tinnitus, pruritus, dermatitis exfoliative, ukuqubuka noma izilonda bullous kwesikhumba, i-erythema multiforme, imfiva, purpura, photosensitivity, vasculitis;
• thrombocytopenia, leukopenia, eosinophilia;
• agranulocytosis, sebethule calcium izinso, isifo sokulahlekelwa igazi aplastic;
• isisa kusayithi umjovo.

Lapho ukubona udokotela?

Manje uyazi, onjani ohlangothini ukuphendula angabangela ikhambi "Lasix" (ampoules). Yokusetshenziswa (ezinganeni nakubantu abadala, umuthi ikhuthaza imiphumela efanayo) uveza ukuthi izinguquko esithombeni igazi, kanye isikhumba ezinzima iguliswa noma ukusabela anaphylactic kungase kudale ingozi izimpilo zeziguli. Ngakho-ke, uma noma iyiphi ukubonakaliswa okungekuhle akufanele kumele ubonane nodokotela masinyane.

izinyathelo zokuqapha

Okufanele ukwazi ngaphambi kokusebenzisa ikhambi "Lasix" (e ampoules)? Yokusetshenziswa (for namakati iyindlela hhayi nezilwane efanelekayo alinikeziwe) ihlinzeka ukuthi ngaphambi kokuqala ukwelashwa kuyadingeka ukukhipha khona yokuphazamiseka abashe outflow umchamo.

Phakathi ukwelashwa kungcono ukudla okucebile-potassium. Uma kungenjalo, kudingeka uthathe ejenti potassium-ungahawukelanga.

Eminye yale miphumela engemihle ingase iphazamise ikhono lomuntu ukugxilisa ingqondo, okuyinto iyingozi kakhulu lapho esebenza imishini eyinkimbinkimbi futhi ukushayela.