Kuyini izinga IVF hCG. DPP - lokho. Ithebula kwezinkambiso hCG ngemva IVF

Ngo kokukhulelwa kwesibeletho - imibhangqwana eminingi kungenzeka ithuba lokugcina ukuthola ingane oyifunayo ezinjalo. Omunye izinkomba ebaluleke kakhulu ukuthi ukukhulelwa okhula evamile - a hCG hormone. DPP - lesi sibalo nakho kubalulekile kakhulu kokuhlaziywa sokukhulelwa ezalandela IVF. Ake sibone ukuthi yini amanga phansi lezi izifinyezo.

IVF - yini iphuzu

Yiqiniso, wonke umuntu uyazi ukuthi ukuze ingane, isidoda (ubulili amaseli besilisa) ukuhlangabezana futhi zalisa iqanda (female germ cells). Ngemva kwalokho-ke ukusebenza ulwelwesi kwesibeletho, ke sibhekana uchungechunge izinguquko ezenzekayo izinyanga eziyisishiyagalolunye, ngemuva kwalokho ingane izalwe. Ngokuvamile imbangela ukungabi nenzalo, kusuka kube nzima ukufeza izinqubo ezimbili vivo. Okungukuthi, ukuze ezihlukahlukene izizathu zokuthi kungani isidoda abakwazi ukuzithiba zalisa iqanda, noma iqanda kakade avundiswa akakwazi ukukufinyelela kwesibeletho noma ngesinyenyela ke. Kodwa naye lo wesifazane uyakwazi ngokugcwele nomntwana. Bese esimweni odokotela beze. Ukuthatha amaseli ubulili bobabili abazali, bachitha e kokukhulelwa kwesibeletho futhi ethula umbungu okuholela zibe endometrium. Yiqiniso, le ncazelo ingesi kwendikimba kakhulu. Ngakho, inqubo nje ebamba isisu lula, kanti imibhangqwana eminingi uthole ithuba.

DPP

iqanda eselivundisiwe (bungu) kuthiwa ozotshalwa esibelethweni ngosuku 3 noma 5 emva kokukhulelwa. Kulokhu, phakathi naleyo nqubo ethula hhayi owodwa kodwa washo emibili imibungu. Lokhu kwandisa amathuba ukuthi ukukhulelwa namanje. Noma kunjalo, kungenzeka ukuthi une ukuphinda lokhu inqubo izikhathi eziningana. Ngokuvamile ukuthi umbungu akuthathi impande ngisho wesibili umzamo yesine nofana yesihlanu. DPP isifinyezo ukuthi mangaki izinsuku Sekudlule kusukela esethulweni umbungu. Lolu suku kubaluleke kakhulu ukuze uqiniseke ukuthi ukukhulelwa kuyadingeka ukulinda 14 DPP. HCG ezingeni lapho kukalwa kule eside, nophawu eyinhloko umcimbi.

I hCG-hormone okuthiwa i

Human chorionic gonadotropin (hCG) evamile kunqunywa kuphela emzimbeni nokuthumba owesifazane owayezithwele. It uqala ukukhiqiza amaqanda, kodwa njengoba ingena emzimbeni womuntu wesifazane isivele avundiswa, ukubonakala kwale hormone egazini noma umchamo ibonisa ukuthi isingeniso umbungu kuphumelele. Kukholakala ukuthi ukukhulelwa lapho hCG kuyinto 14 DPP pyatidnevok (imibungu lwenteke ngosuku lwesihlanu emva kokukhulelwa livelile) lingaphansi kuka 100 Miu / L. Uma ukusebenza 25 Miu / L noma ephansi, cishe, kuyodingeka usuphinda. Nokho, amagugu engezansi le ukuhlaziywa kungaba futhi uma ngokuhamba kwesikhathi ngemva umbungu yenzeka ngokwanele, isib, 12 ukucacisa hCG DPP.

Yini hCG

Chorionic gonadotropin ubizwa nangokuthi hormone sokukhulelwa. Ngokushesha emva kokukhulelwa, awusebenzi abaphindela umzimba ophuzi kanye kuvusa zamagama hormone ezifana estrogen futhi progesterone. Serum hCG kunqunywa ngokushesha ngemva iqanda sethulwa ulwelwesi lesizalo. Ngemva kwalokho, lo lokuhlushwa uqala zikhule ngokushesha. Ngokuhamba evamile yokukhulelwa zonke izinsuku ezimbili, ke kuyokwenziwa kabili. Izinga esiphezulu hCG (DPP) ibhalisiwe ubheke leli sonto yeshumi. Ngemva kwalokho, izinga kwale hormone kancane kancane amasonto 8 bese yaqhubeka iba ngcono kuze kwezidingo.

Kufanele kuqashelwe ukuthi odokotela eduze nokuqapha izinga lama-hormone in the serum igazi kanye isilinganiso hCG - DPP futhi ngenxa ngeziphambeko okukhulu kusukela imingcele Inkomba kwezinkambiso ngokuvamile ube marker kwezinso sina emzimbeni kamama, nokunye, ekuthuthukiseni umbungu.

Izindlela ekutholweni human chorionic gonadotropin

Abesifazane abaningi emva yimpumelelo IVF hCG ezingeni izinguquko ziqala ukuba ziqashwe kakade ezinsukwini 9-14. Kuze phendla ukubonakala kwawo ngisho ngokuzikhethela banikele ngegazi. Ukukhulelwa ukuhlolwa ukusebenza isimiso ukuzimisela khona layo umchamo. Yiqiniso, abazi ukhombise izinombolo ngqo kanye nenani hCG ku DPP pyatidnevok noma trehdnevok, kodwa ukuba khona kwakhe ngeke cishe abonisa okukhulelwa. Ukuze uthole imiphumela esinembile owesifazane kaButhelezi igazi. Uma ngesikhathi evamile sokukhulelwa igazi hormone ukuze iqashwe e Ukuhlolwa, okuyinto wenziwa senyanga yokuqala, lapho siqhuba kwesibeletho fertilization okwesikhathi ngaphezulu ulwazi isithombe gynecologists Ngincoma ukuba wenze njalo ezinsukwini ezingu-2-3 ngemva umbungu yenzeka. Imiphumela etholwe iqhathaniswa itafula elibonisa ubuncane, esiphezulu kanye isilinganiso namagugu hCG isikhathi esithile lo DPP.

nemithetho hCG

Njengazo zonke izinkomba, amazinga hCG ingahluka ngaphakathi kwemingcele ethile. Ngokuvamile ethebuleni idatha ikhombisa ekushintshashintsheni ezingeni layo ngeviki sokukhulelwa. Kukhona itafula okubonisa izinga le-hormone hCG kwandisa ukusebenza emini. Ziyakwazi kakhulu ewusizo kulabo okwenziwa IVF. Ithebula elingezansi libonisa amagugu isilinganiso sithola usuku olulodwa nje emva isingeniso (DPP) ngoba imibungu ezifakelwa ngemuva 3 no-5 emva kokukhulelwa.

Njengoba singabona, hCG 7 pyatidnevok DPP kuyinto 45 Miu / L, kodwa ngokuvamile ukusebenza yayo ziyahlukahluka kusuka 17 kuya 65 Miu / l. Ngosuku olufanayo, isilinganiso isikhathi umbungu wezinsuku ezintathu kuyinto 18, kanti uhla evamile bekungaba 8-26 Miu / L.

Izizathu hCG okwandisa

Njengoba kushiwo ngenhla, i-hCG akuyona kuphela inkomba ukuthi ukukhulelwa, kodwa futhi ikuvumela ukuba ukulawula flow yayo. Esimweni lapho ezingeni le hormone hhayi okuningi okudlula kuyinsakavukela, awusebenzi unamathisele ukubaluleka kakhulu, kodwa uma izibalo awafani DPP hCG kakhulu, kungaba uphawu lokuthi kukhona pathologies ezibucayi kumama nele-fetus. A ukwanda okukhulu kule Inkomba kungaholela:

• kwezinso chromosomal e kwengane esiswini (Down Syndrome);
• isimila trophoblastic;
• endocrine iziyaluyalu (isifo sikashukela);
• imithi aqukethe progestogens;
• nokukhulelwa izingane eziningi ngasikhathi.

Izizathu ekuncipheni hCG

Okuphansi ezingeni harioticheskogo gonadotropin kungatholakala kulezi zimo ezilandelayo:

• isisu okule;
• Uphuthelwe isisu;
• ukukhubazeka kombungu;
• ukufa fetus ;
• perenashivanie nokukhulelwa;
• esingamahlalakhona esinomhlapho;
• ukhulela ethunjini.

Ukwandiswa hCG DPP. twins

IVF yokuthuthukisa amathuba owesifazane abe ekhulelwa, ngokushesha ezifakelwa imibungu ezimbili, kodwa lokhu ngokuvamile akuqinisekisi impumelelo inqubo. Nokho, kukhona izibonelo lapho ababili bayoba nezimpande ngaphansi ngokushesha. Kuleso simo hCG izinkomba angase akhule ngokuphindwe izikhathi ezingu-2-3. Lokhu kungenxa yokuthi uveza hhayi placenta olulodwa, njengoba kwenzeka ngo-ukukhulelwa Singleton, kodwa ababili. Ngokwesibonelo, uma ezingeni hCG ku DPP 16 pyatidnevok ezomhlaba 1960 Miu / L, izinga evamile amawele ukuba 3920 Miu / l nangaphezulu.

HCG inkomba e sitholakele anomalies fetus

Yiqiniso, ukukhulelwa - kuyinto isenzakalo esibaluleke futhi okulindeleke empilweni noma yimuphi owesifazane, kodwa-ke kwenzeka ukuthi akugcini injabulo kuphela, kodwa futhi nakho. Against isizinda ukucindezeleka, imvelo kanye nezinye izinto, hhayi indlela engcono kakhulu ezithinta impilo wazalwa, kukhona ingozi ukuthuthukiswa pathologies. Izinga yesimanje wezokwelapha ivumela abaningi babo ukuxilonga ngisho lesifanele kusaqalwa. Kungenxa yalesi futhi kukhona Ukuhlola okuyimpoqo senyanga yokuqala neyesibili ka sokukhulelwa. Screening of senyanga yokuqala, okuyinto evamile kokuqhuba ngesikhathi amasonto 10-14 kufaka ultrasonography kanye nokuqapha hCG izinga lama-hormone kanye PAPP-A. Okwesibili senyanga Ukuhlolwa okwenziwe ku 16-18 ngesonto. It, kanye US, ubambe ukuhlolwa kathathu (hCG, abezindaba ze-AFP, estriol). Idatha yale Ukuhlolwa yesibili uvumele ukunquma nge awokuthi khona okuthile okungahambi kahle emzimbeni. Esimweni lapho ku isizinda amazinga aphansi AFP futhi estriol amazinga hCG siphezulu kunokuvamile, nge awokuthi singakwazi usola khona fetus syndrome Down. Syndromes Edwards noma Patau zixwaywe ezingeni low zonke izimpawu ezintathu. Kuqhathaniswa amazinga evamile human chorionic gonadotropin e-AFP ongaphakeme futhi estriol kungase kubonise Turner syndrome.

Zonke izibikezelo ezenziwa esekelwe izici ngamunye ukukhulelwa kokuqhubeka - yobudala kwabakhulelwe, isisindo sakhe, imikhuba emibi, comorbidities, isifo ezinganeni azalelwe ukukhulelwa odlule. Uma kuhlola kwembula ngisho ngeziphambeko ezincane kusukela evamile yowesifazane eziphoqelelwe ngalolo zofuzo ukubonisana.

Kanjani ukuba bahlolelwe

Ukuze Assay ngoba hCG liyadingeka ukudlula igazi emthanjeni. Kwenze kangcono ekuseni futhi bezila ukudla okuqinile. Kuleso simo, uma kuzodingeka ngiyithathe ngosuku, udinga sigweme ukudla lokungenani emahora lalingana langu-6. Kuleso simo, uma imithi oyiphuzayo eziqukethe hormone ( "Pregnil", "Horagon"), kubalulekile ukuthi utshele udokotela wakho kusengaphambili.

Ukuze ucwaningo laboratory kwaba ngaphezulu ulwazi, ukwenza ngcono, izinsuku ngaphambili kuka 3-5 ngemva kokuya esikhathini. Endabeni IVF idatha olunembile kunazo kuyodingeka ukuxilongwa eyenziwa ngosuku lwe-14 ngemva kokuhlinzwa.