"Antabuse" amaphilisi-mbumbulu. Ukubuyekeza, intengo Umhlahlandlela

It ngokuthi ukuba umlutha wotshwala isifo libhekene yokuluthwa ethanol nge ukwencika ezingokomzimba nezingokwengqondo kuso. Lolu hlobo lokuhlukumeza. Kuleli zinga, ukulahlekelwa ukulawula inani utshwala udakwe kwandisa ukubekezelelana kuso (ukufeza ukwaneliseka utshwala njalo umthamo okwandisa) kanye zokuqaleka syndrome kwenzeka, kuthinta izibilini avele inkumbulo iphelelwa isikhathi.

Iziguli ukuba umlutha wotshwala, ngokuthi yotshwala. Ukwelapha lesi sifo kufanele kube ngokwengqondo nangokomzimba. Isikhathi esining impela, odokotela linqume lokhu izidakamizwa abantu "Antabuse". Yokusetshenziswa, intengo nemithi, ukubuyekezwa yezokwelapha aboniswa ngezansi.

Ukupakisha, umumo, futhi incazelo isakhiwo

Ngayiphi yakha izidakamizwa sithengiswa "Antabuse"? Nobufakazi ukubika ukuthi ikhambi elinjalo angathengwa ngesimo ezimhlophe, round amaphilisi effervescent. Ziyakwazi flat, onqenqemeni beveled, ingozi futhi kumakwe «CD» futhi «C» ezinhlangothini ezilwisanayo izingozi.

Ukwakheka le imithi zihlanganisa disulfiram. Ngaphandle-ke, ekulungiseleleni iqukethe corn isitashi, povidone, sodium hydrogencarbonate, tartaric acid, colloidal Silicon dioxide, talc, microcrystalline cellulose kanye magnesium stearate.

Tablets "Antabuse" afakwe nezipakupaku futhi upaka amakhadibhodi.

izici pharmacodynamic

Uyini izidakamizwa "Antabuse"? Manual ithi lokhu kusho antialcoholic. It kuvimbela acetaldehyde dehydrogenase, okuyinto ehilelekile umzimba ethanol. Alibale inqubo yayo namachibi kubangela ukunqwabelana utshwala kanye nokuthuthukiswa ukudakwa eqinile, kulandele imizwa esindayo njengoba ubuhlungu throbbing futhi umsindo ekhanda, tachycardia, palpitation, ukunciphisa umfutho wabo wegazi, isicanucanu, angaboni kahle nokuhlanza.

Ngokusho kochwepheshe, lezi zimpawu ezingemnandi neqhaza ekuthuthukiseni ekhondishina enyanya reflex kuya utshwala.

izakhiwo pharmacokinetic

Kanjani ukumuncwa "Antabuse" izidakamizwa? Manual ibonisa ukuthi isidakamizwa amuncwa 70-80%. He is kakhulu oncibilikayo lipids futhi avame ukunqwabelana edepho amafutha.

Ingqikithi asebenzayo we agent ngokushesha kakhulu akheka, kuphumele metabolite siguqulwe - ester methyl dietiltiokarbaminovoy acid. igazi lokuhlala wayo isiqongo kunqunywa emva 4 h. Nakuba umsebenzi maqondana acetaldehyde dehydrogenase siyenzeka kuphela emva kwezinsuku ezintathu.

Ingxenye-ukuphila umuthi amahora 10. Ngaphezu kwalokho, umsebenzi wayo imelane nayo aldehyde dehydrogenase iqhubeka isikhathi eside. Ngakho-ke, ngemuva kokuhoxiswa umphumela izibhebhe kuyagcinwa eminye izinsuku 7-14.

Umuthi ivela umchamo, futhi ngokwengxenye ngokusebenzisa amathumbu nge air ngamakhala.

ubufakazi

Kwezinye izimo, umuthi ephumelela kunazo iziphatha "Antabuse"? Izibuyekezo babike ukuthi lesi sakhiwo kabanzi nokuvimbela lokubuya kwesifo ekwelapheni utshwala nokuluthwa utshwala.

Izimo

Uma akufanele bathathe 'Antabuse "ithebhulethi? ochwepheshe lezivakashi bathi kubhekwe izidakamizwa akufanele enqunywe wumgomo, uma:

• ukufiphala;
• neuritis we-optic futhi izinzwa sokuzwa;
• isifo sofuba yamaphaphu;
• inhliziyo futhi semithambo izifo (isib post-infarction uthi, uzwakalise cardiosclerosis, isifo sokuqina kwemithambo yegazi imithambo palsy, isifo unesifo sikashukela, isifo sokuvuvukala kwemithambo yomthambo i-aorta);
• polyneuritis yanoma yimuphi umsuka;
• sikashukela;
• emphysema, isifuba somoya bronchial;
• thyrotoxicosis;
• ukugula ngengqondo, isithuthwane futhi epileptiform syndrome;
• isimila esibulalayo;
• hepatic ezinzima futhi ukwehluleka kwezinso;
• yezifo hematopoiesis;
• exacerbation of peptic isilonda isifo;
• ukhulelwe;
• hypersensitivity.

Phawula futhi ukuthi lokhu izidakamizwa kukhona Izimo isihlobo:

• kweminyaka eyi-60;
• imiphumela sohlangothi kanye nezimpawu asalile;
• isilonda peptic (kufaka phakathi ukuthethelelwa);
• kusheshisa ukuba sengqondo.

Izidakamizwa "Antabuse": yokusetshenziswa

Intengo Anti-utshwala iphilisi ezisohlwini ekupheleni sihloko. Kufanele uthathe bawo bubhekene ½ ngaphambilini ziyoncibilika ingilazi yamanzi.

Ngokuvamile, odokotela linqume 200-500 mg izidakamizwa kanye noma kabili ngosuku. Ngemva kwezinsuku ezingu-7, qiniseka ukuchitha disulfiram-utshwala test. In parallel yokwamukela 500 mg nomuthi iziphuzo nesineke 20-30 ml likagologo. Uma ukusabela ibuthakathaka ke ukwandisa umthamo utshwala ukuze 20 ml.

Lokhu test liphindwe izikhathi eziningana. Kamuva ballroom ebekiwe yesondlo umthamo mg 200 nsuku zonke iminyaka 1-3.

ukusabela ezingezinhle

Tablets "Antabuse", okuyinto izilinganiso ethulwa ngezansi kungabangela imiphumela eminingi engemihle njengezindlela elandelayo:

• kwesibindi, asthenia, ukunambitheka metal emlonyeni;
• ukubonakaliswa cutaneous, polyneuritis izinyawo;
• Ukukhohlwa okungamahlalakhona, ubuchopho ukuvuvukala, ikhanda;
• isilethikusebenza, arrhythmias inhliziyo;
• nokuvaleka kwemigudu yokuphefumula, nciphisa zenhliziyo;
• neuritis optic, izitsha thrombosis cerebral;
• kwengqondo angina.

Nomuthi "Antabuse": Izibuyekezo lodokotela kanye nentengo

Izindleko amaphilisi anqanda utshwala kuyinto ruble mayelana 450-600 (kuncike umthamo kanye nenani iphakethe ngalinye).

Odokotela linqume izidakamizwa ezinjalo, ngokushesha waxwayisa eziyingozi ukuthi kungavuka nesineke ngemuva kuzothatha. Ngakho-ke akuvumelekile ukuba aphathe ngokwakho noma imfihlo kusukela nesineke.

Kufanele kuphawulwe ukuthi ochwepheshe eziningi ziyavumelana ukuthi imithi eminye esebenza ngempumelelo ezicindezela ukuqalekela utshwala, akukho. Futhi le ndlela akuyona yokwelapha. Limane likhuthaza ukuthethelelwa esitebeleni.