Umuthi 'Tamsulosin ": yokusetshenziswa, intengo, ukubuyekezwa kanye analogue

"Tamsulosin" antidizuricescoe ngeyona izidakamizwa futhi lisetshenziswa njengendlela lingaze urinary modulator inqubo yezifo urological kubangelwa cell-ebulalayo wendlala izimila uhlamvu. Mshini ukuphendula uwukubonakaliswa ukwehla kancane kancane ukushuba kule imisipha abushelelezi wendlala yabesilisa, kanye ukuphumula entanyeni esinyeni. Ngaphezu kwalokho, kukhona abakhethayo ivimbela urethral-alpha 1A-adrenretseptorov, okuholela nekunciphisa imiphumela waphawula isimiso - umphumela engokwemvelo ukuthuthukiswa adenomas.

izici kwemithi ye "Tamsulosin"

Absorption zomuthi ezisebenzayo kuleli pheshana emathunjini lingafika ku-100%. Ucwaningo waqinisekisa ukuthi ukumuncwa luyanda lapho ukuthatha amaphilisi ngemva kokudla. I degree of nokwenziwa wakhona isikhathi langemva kusukela ukusetshenziswa zomuthi (ngamanye amazwi, kukhona kinetics lwento). Ubuningi isiqongo we reactants e -plasma litholakala ngemuva kwamahora ayisithupha (olulodwa umthamo 400 mg). Nokho, ngalesi sikhathi ingase yehluke kuye ngesistimu engu-isiguli.

Kuyaqapheleka ukuthi reception ngesikhathi usithole ngokuhamba kwezinsuku ezinhlanu, emakamu yezingxenye ku inyuka plasma by 60-70%. Tamsulosin hydrochloride ngokwanele kancane ungena izinqubo umzimba: abatholako ephelezelwa ukwakheka metabolites esitebeleni ezithinta selectivity ephezulu alpha 1A-adrenoceptor.

izinkomba

Umuthi 'Tamsulosin "imfundo manual libabiza njengenhlangano agent for ekwelapheni Benign Prostatic Hyperplasia, lingaze okukhulu (adenoma, dysuria, nezinye ephansi zangasese ipheshana isifo).

Njengoba izifundo zokwelapha ungazange sembule ukusabela ezibucayi ezinye izinto of wathi iqembu eyenza imithi, bese azikho imingcele ukusetshenziswa 'tamsulosin "njengesisusa esisemqoka asizayo yezokwelapha ekuvimbeni abakhethayo-alpha-1a adrenergic yokwamukela.

Isikali ezinconyiwe indlela yokuphathwa

Ukuswelakala kokusebenza ngokuhlanganyela umphumela hypotensive - isici isici izidakamizwa "Tamsulosin". Yokusetshenziswa lithi isidingo Ukukhetha umthamo bubodwa - ngokwanele ngomlomo iqondiswa micrograms 400 zomuthi ngemva ibhulakufesi (2 Amaphilisi / amaphilisi enesisindo mg 200 ngamunye, noma 1 capsule / ithebhulethi enesisindo 400 mg). Ngaphezu kwalokho, lokhu yangosuku akudingeki ukulungiswa, ngisho uma isiguli uzigcinile ngeziphambeko ingane izinso noma isibindi. Noma kunjalo, ukuqala inkambo zokwelapha kumele kube nenkulumo yamaphuzu sokutholakala ukuthi une-ngqo ukuze ukuvala amathuba umdlavuza wendlala. Futhi nhlobo phakathi ukwelashwa ziyisibopho luhlolo rectal.

Amaphilisi Abonayo kanye amaphilisi "tamsulosin" akufanele ukuhlafuna - kokunikezwa kwe-imvilophi kungathikameza kabi izinga ukukhululwa kwe-reagents asebenzayo. Ngokushesha ngemva kokuthatha izidakamizwa Kunconywa ukuba baphuze amanzi. It is nhlobo ukusebenzisa "Tamsulosin" kulesi sikhundla lisalele.

ukulinganiselwa ekhona kanye contraindications

Umuthi 'Tamsulosin ", intengo zazo, kuye umenzi kanye emaphaketheni ifomethi, ububanzi ruble 400-1700, yenzelwe kuphela amadoda. Ngakho-ke, ucwaningo ku nemiphumela yayo i-fetus ungazange besiba ngesikhathi sokukhulelwa. kuphela kadokotela inikezelwe idatha ithebhulethi, okungukuthi, sitholakele "Hyperplasia Benign Prostatic" Kumele kube khona inhlolovo (nge saziso ngaphambi kokuhlolwa umdlavuza).

Phakathi contra - hypersensitivity kuya "Tamsulosin" izidakamizwa (isicelo Umsebenzisi iqukethe uhlu eningilizayo yazo zonke lezi reagents asizayo). Kuyinto engathandeki ukusebenzisa wathi ejenti hypotension orthostatic kanye nezifo ezingamahlala khona kwesibindi noma izinso (ezimweni ezinjalo, udokotela kufanele ukulinganisa izinzuzo ezingaba khona ukusetshenziswa "tamsulosin" futhi kutholakale umsuka wendaba yesihluku kungenzeka imiphumela emibi yenkambo zokwelapha).

Nge reception njalo ukukhanya kuvunyelwe isiyezi, ngezinye izikhathi indawo isimo semiconscious. Abashayeli bezimoto kanye nezisebenzi, imisebenzi kabani professional ukubandakanya usongo yokulimala, kufanele agcine ngokucophelela okukhulu e ukusetshenziswa ketshezi.

side effects

Njenganoma iyiphi enye izidakamizwa, kunemiphumela emibi futhi izidakamizwa "Tamsulosin" (intengo kwezempilo zamadoda kuphezulu, nokungezwani komzimba nezinto ezincane, ukuze ukusabela ezingezinhle kubhekwe njengoba ukuntuleka abalulekile akusiyo kunesidingo).

Ngo parallel luphulukisa kungathatha indawo:

• ukuphathwa ikhanda;
• ukuluma kwesikhumba;
• ubude sohudo;
• arrhythmias inhliziyo;
• ubuhlungu okhalo.

"Tamsulosin" Ngezinye izikhathi, analogue okutholakalayo kabanzi emakethe, okubangela iziguli ukuqwasha noma, Ngakolunye uhlangothi, ukozela ngokweqile. Ezimweni ezingavamile - ukuhlukumeza yesikhashana kwesitulo futhi buthakathaka potency.

Overdose, zako kanye neutralization

Izimpawu ukweqisa izidakamizwa, egcwele phetho umuthi "Tamsulosin" (yokusetshenziswa ukuxwayisa lokhu), kungashiwo liphinyiselwe acute hypotension. Futhi nakuba amathuba kule ndaba eliphansi kakhulu, i-algorithm zisize nokho wenza:

• ngokushesha anikeze isiguli evundlile;
• uma kunesidingo, afeze eziyinkimbinkimbi izinyathelo ezihlose ngesikhathi ukuzinza kohlelo senhliziyo umzimba;
• ukuqinisekisa nemisebenzi izinso (apharathasi uxhumano kwezindlela igazi uhlanzekile zingenzeki ngoba isithako esebenzayo kahle elihlobene ne-compounds plasma amaprotheni);
• kubangele ukuhlanza e isiguli ukuze ayeke ukumuncwa obengeziwe reactants (nakho kuyiqiniso lavage esiswini ngokusebezisa okucishe kufane nalokhu laxatives);
• ngokungabi bikho Dynamics ngcono ukusebenzisa imithi ukufukula kwegazi igazi.

ekusebenzisaneni izidakamizwa: ubunjalo ukusabela

"Warfarin" futhi "Diclofenac" qualitatively nomthelela ijubane okukhiphayo "Tamsulosin" izidakamizwa omzimba (intengo izidakamizwa eside, kodwa umphumela kuwufanele). Nokho, kokuma isikhathi eside ngokuphathelene ukusetshenziswa ahlangene le mithi isibhedlela akulona kwenziwe, ngenxa yalokho, ngokucophelela okukhulu Kunconywa. "Atenolol" futhi "Enalapril" akusho uxhumana wathi impahla, "cimetidine" ikhuthaza lokuhlushwa "tamsulosin" plasma, futhi "Furosemide" kunikeza yi ngokuphelele okuphambene.

Inqubo ukwehlisa umfutho wegazi cuphuluza edonsa nomuthi kungase ukugqanyiswa ngenxa ukusetshenziswa ngesikhathi esifanayo namanye-alpha-1A adrenoblokatorovv isisu futhi imithi ebulala izinzwa. nomthelela obonakalayo le kinetics kwemithi kwamafrakshini khulula "Diazepam" futhi "chlormadinone" by ukulungiselela "Tamsulosin" imfundo manual (intengo ngenhla izindlela -. 500-1400 RUB) akachaziwe.

izimo Isitoreji eshalofini yokuphila

On izimo isitoreji izidakamizwa "Tamsulosin" Umhlahlandlela uthi lokhu okulandelayo:

• ephephile lokushisa ububanzi - 15-25 degrees Celsius;
• umswakama elikhulu - 70%.

Imfuneko okokusebenza isitoreji asemaphaketheni yasekuqaleni (endaweni ezingafinyeleleki izingane, okuyinto kahle avikelwe elangeni).

Lapho wonke amaphuzu imiyalelo iziqiniseko umakhi ukuthi nomphumela oqabulayo "Tamsulosin" ngeke buthaka izimoto kule minyaka emibili kusukela ukukhululwa walo.

Izidakamizwa analogue "Tamsulosin"

Uhlu "kabili" imelelwa amaqembu amabili izidakamizwa. Isigaba sokuqala sihlanganisa izidakamizwa, ezivamile, kwesibili - amagama ukuhweba ezingavamile.

izimali zomphakathi zokuhamba:

• "Omnic" (yokuqala - Omnic), umkhiqizi - eNetherlands, ifomu Ukukhululwa - amaphilisi / amaphilisi 10/30 izingcezu iphakethe ngalinye, intengo uhla - ruble 380-1700.
• "Proflosin" (Proflosin), eJalimane, amabhamuza amaphilisi 30, izindleko ezilinganiselwa - ruble 500.
• "Sonizin" (Sonizin), Izwe Lokudabuka - Romania, iphakheji esezingeni 10 noma 30 amaphilisi, isilinganiso senani - ruble 450.

zokuhweba kanye namagama yokuhweba noma izidakamizwa "Tamsulosin" Okunye (analogs okungabonakali ezivamile noma ukudedela amafomu kakade sezilithathile out of umkhiqizo):

• "Omsulozin" (Omsulosin), eNdiya, amaphilisi 0.4 mg (30 nama-PC.) Amabanga wentengo kusuka 350 ruble 550.
• "Tamsulosin-Teva" (Tamsulosin-TEVA) ukuthi: "UTamari-Actavis" umkhiqizo inkampani, Greece, ukuma iphakeji intengo kuyafana esimweni sangaphambilini.
• "Tamsulosin-kuthiye ukukhula" ( "understudy" okuqhubekayo ukukhululwa ingxenye), emgqeni ukukhiqizwa bazinza Russia, amaphilisi 400 mg, izindleko - ruble mayelana 300-360.

"Tamsulosin": ukubuyekezwa kodokotela kanye neziguli

ukwelashwa Medical nale izidakamizwa ngokuvamile yimpumelelo futhi ikhonjiswe kahle a izinkulumo ekuhlehleni umuntu azalwa nalo lokuhlaziya non-ebulalayo wendlala izimila.

Ngemva kweminyaka ecishe ibe ngu-90 izinsuku izimpawu sebehlala e 2 izikhathi, nezinguquko lokuqala lubonakale kakade waphawula ezinsukwini 14-21. Lapho beqeda izimpawu ukuwa Inkomba ngo-75% (ngokuziqhathanisa isigaba kokuqala), okuyinto nakanjani umphumela eyamukelekayo.

Beautiful tolerability "Tamsulosin" (Umhlahlandlela intengo kanye nezidakamizwa ezivamile kuyizincomo letinikwe lapha ngenhla) kwenza kube elula kakhulu ukusebenzisa nawabela iziguli ekwelashweni. Nokho, ukuze sifinyelele umphumela esiphezulu ezingaba efana is enganele, kunconywa ukuthi imishanguzo ngesikhathi esifanayo nezinye izindlela kanye nemikhiqizo ezithaka imithi.