Bismuth tripotassium dicitratobismuthate - antiulcer ejenti

Bismuth tripotassium dicitratobismuthate (tradename - izidakamizwa "De-Nol") kuyindlela ephumelela anti-isilonda izidakamizwa kokuba umsebenzi evelele amagciwane ngokumelene nezilwanyana ezincane zohlobo Helicobacter pylori. Ngaphezu kwalokho, lokhu izidakamizwa has antacid, antiinflammatory nemiphumela astringent. Ukuthola lokhu kusho izikhathi eziningana ngcono izici zokuzivikela mucosal emathunjini ebusweni, ukwakha enamathela ekhethekile zingaxazululeki ngqo esizeni isilonda. Futhi bismuth tripotassium dicitratobismuthate kwandisa ukuzinza imvilophi isisu namathumbu ukuze imiphumela emibi ye-enzyme pepsin futhi hydrochloric acid kwandisa ukukhiqizwa isikhwehlela, uketshezi of Bicarbonate futhi prostaglandin zamagama ohlobo E. Ngaphezu konke okungenhla, ochwepheshe bathi ikhono layo ukuze sikhuthaze umsebenzi izindlela cytoprotective.

Ngokuqondene pharmacokinetics ye-ejenti anti-isilonda ke ngenxa inkambo emakamu yakhoibrium egazini usufinyelelwe kwase kuphele izinsuku ezine kuya kweziyisihlanu, nakuyo inxenye impilo mayelana kwezinsuku ezinhlanu. Kulokhu isithako esebenzayo excreted ngokuphelele emzimbeni kuphela ngemva kwamasonto nambili emva ekuqaleni yokwamukela ithuluzi ezifana bismuth tripotassium dicitratobismuthate. Analogs ithuluzi - Amaphilisi Abonayo "Bismay" "Desmol" futhi "Novobismol" - unayo indlela efanayo senzo.

Lokhu kukhiqizwa i izidakamizwa antiulcer ikakhulukazi ngesimo ezivamile nemithi dragees camera. Thatha iphilisi "De-Nol" (bismuth tripotassium dicitratobismuthate), ogama intengo ezingabizi kakhulu, umenzi uncoma kuphela ekwelapheni isilonda 12 isilonda duodenal noma isisu. Abantu abaphethwe kolwelwesi ezingamahlalakhona kufanele futhi baqala njalo kokuthatha lesi imithi. Ngaphezu kwalokho, i-bismuth tripotassium dicitratobismuthate usizo ngokushesha uma dyspepsia, okungezona organic izifo emathunjini.

Thatha anti-isilonda odokotela izidakamizwa sebekubeke enqabela nge ezinzima nezinkinga kwezinso, kanye ngesikhathi sokukhulelwa. ukuzwela Ukwandiswa futhi ibele inkathi nosana efanayo kufakwe ohlwini Izimo esiqinile. Iziguli cha attained engu-nambili, futhi akufanele uqale ukuthatha imithi, okuhlanganisa bismuth tripotassium dicitratobismuthate. Ngaphezu kwalokho, kufanele ngaso sonke isikhathi khumbula ukuthi abantu tinhlobo letehlukene abakhubazekile umsebenzi izinso ngenxa ukusetshenziswa nokunwetshiwe ebulilini le-ejenti angagcina encephalopathy.

Uma sicabangela ukusabela ezivamile ezingezinhle, okuvela kuyo okungase kubangelwe yokwamukela izidakamizwa antiulcer, ngokuyinhloko kudingekile ukwaba ukuhlanza, isicanucanu noma ikhishwe yisisu. Ngaphezu kwalokho, kukhona ingozi kahle eliphezulu of ukuqubuka kwesikhumba, ukulunywa, ububomvu kwesikhumba futhi angioedema.