Umuthi 'Betaxolol ": yokusetshenziswa, incazelo, ukwakheka kanye nokubuyekeza

Drops ngoba amehlo "Betaxolol" (incwadi yeziyalezo libabiza abakhethayo beta-blocker isenzo isikhathi eside) asetshenziswa umkhuba amehlo, kanye amaphilisi kabanzi ekwelapheni ezihlukahlukene izifo zenhliziyo nemithambo yegazi.

Khipha ifomu kanye nokwakheka

Kusho "Betaxolol" ikhiqizwa ngendlela amaphilisi kanye iso amaconsi. Omunye ithebhulethi ezimhlophe camera nge enamathela ifilimu equkethe mg isithako esisebenzayo betaxolol hydrochloride 20. Njengoba izithako ezingeziwe: carboxymethylstarch sodium, magnesium stearate, microcrystalline cellulose, monohydrate lactose, aerosil. Ukwakheka igobolondo yakhiwa polyvinyl utshwala, emhlophe Opadry 2, macrogol, talc, ama-titanium dioxide.

Phama izingcezu 10 aluminium amabhamuza amaphilisi "Betaxolol." Ukufundiswa ukusetshenziswa is ebiyelwe ebhokisini amakhadibhodi.

Ekudonseleni iso ngamunye 1 ml ama-akhawunti 5.6 mg isithako esisebenzayo betaxolol hydrochloride. izinto yesibili ehlanganisa mithi: hydroxide sodium, benzethonium chloride, hydrochloric acid, dihydrate, disodium edetate, i-sodium chloride, amanzi. Le into esobala aphuzi. Ikhambi Ngaleso ebiyelwe ibhodlela-IV (5 noma 10 ml). liphele Okuningi futhi weThrojani tube ngesikhathi umthamo 1.5-5 ml. Ebhokisini amakhadibhodi wafaka imiyalelo ibhodlela-weThrojani.

Impilo eshalofini futhi eshalofini

Impilo izidakamizwa (amaphilisi kanye iso amaconsi) ineminyaka emithathu. Ngemva kokuvula ibhodlela amathonsi zingagcinwa hhayi ningi than izinsuku ezingamashumi amabili nesishiyagalombili.

Pharmacokinetics

Isenzo kwemithi zomuthi libhekene beta-abakhethayo adrenoblokiruyuschey, antianginal, antihypertensive, antiarrhythmic, antiglaucoma orientation.

receptor Blocks beta1-adrenergic has umsebenzi sympathomimetic, futhi okudlula ulwelwesi eliletha ukuthula izakhiwo ezincane. Kunciphisa ezifweni kwezicubu ukuba catecholamines, kubamba emaphakathi amaza, ke okuvimba uketshezi of renin. Kunciphisa ukushaya kwenhliziyo kunciphisa esivimba amanzi nomoya-mpilo ukusetshenziswa (izakhiwo antianginal). Blocks zenzeka foci ethunjini ku Atria, AV-inhlanganisela.

Umphumela siyenzeka ngemuva kwamahora amabili ngemuva kokungenisa, futhi esiphezulu izidakamizwa lokuhlushwa emzimbeni iqinile e 3-4 amahora futhi kuthathe amahora 12-24 at njalo ukusetshenziswa okwejwayelekile zomuthi izinsuku 7-14. It zivikela umfutho wegazi ngesikhathi umsebenzi nokucindezeleka ngokwengqondo.

Ukwelapha-high blood pressure kungenxa nokuncipha kwesokunxele ventricular eqinile futhi contractile yayo umsebenzi. Mayelana 75% kweziguli okuncane nomfutho wegazi ophezulu isamukele a monotherapy ezinjalo. ukusetshenziswa isikhathi eside zomuthi akuphazamisi ratios lipid umzimba futhi kukhuthaza sodium. Ngo abantu ufuba nasekulweni ukucinana kwemigudu yokuphefumula efomini ezingamahlalakhona akusenzi wamaphaphu function.

Eye lehla "Betaxolol" (incwadi yeziyalezo uthi ngethonya zomuthi ukwehlisa ingcindezi intraocular ngokunciphisa uketshezi intraocular) musa abangele komzimba okufana suku-ubumpumputhe, miosis, spasm yokuhlala, futhi angaboni kahle.

Umthelela kufinyelelwe emva isigamu sehora ngemva isicelo, emakamu esiphezulu waphawula ngemuva kwamahora amabili futhi kuthathe amahora nambili.

Izinkomba ukusetshenziswa

Kunconywe sitholakele "umfutho wegazi ophakeme" Ukulingana ehlala ka ischaemia esivimba amanzi (angina), akathisia, cuphuluza neuroleptics, "Betaxolol" amaphilisi-mbumbulu.

Eyedrops (imfundo manual belulekwa ukuba athintane nodokotela ngaphambi ukuzisebenzisa) siboniswa isifo engela evulekile-glaucoma, umfutho ophakeme wegazi intraocular. Odokotela linqume izidakamizwa ngemva laser trabeculoplasty. Asetshenziswa eside therapy antihypertensive, kwaphakama isidingo okuyinto ngenxa kokungenela amehlo kuhlinzwa.

Izimo yezokwelapha

Naphezu ukusebenza ofakazelwe wokuba "Betaxolol" izidakamizwa (Izidakamizwa Ukusetshenziswa belulekwa ukuba ngokuqinile ukugcina umthamo ebekwe udokotela futhi akazibekanga medicate), ukusetshenziswa kwalo has Izimo ezithile. Lezi zihlanganisa hypersensitivity kuya ingxenye esebenzayo zomuthi, futhi izinto ezengeziwe ngezithako zawo. Iphinde kungavunyelwe lapho fikisruyutsya itheku bradycardia (esingaphansi 45-50 u. / Min) kanye itheku ogulayo. Awukwazi ukusebenzisa umuthi ngaleso AV ukuvinjelwa II-III degree, hypotension. Contraindicated "Betaxolol" abantu ukushaqeka cardiogenic in iziguli ezinzima inhliziyo ukwehluleka kanye ezinzima obstructive nokuvaleka kwemigudu yokuphefumula.

Kufanele kuthathwe izinyathelo in iziguli nenyumoniya okungamahlalakhona, iziguli ezinemishini angina engazinzile, nezici ezithile ukuze bradycardia. Ukuqapha kufanele ntombazane AV-block mina degree, neuropathy ukwehluleka kwegazi. Kumele kube iziguli ngokucophelela ikakhulukazi abanesifo sikashukela, kahle kungakhuphula izinga likashukela, isibindi nesifo sezinso, i-hyperthyroidism. Odokotela kufanele ukuqapha imithi in iziguli ukuba buthakathaka kwezicubu kwasebekhulile kanye nezingane.

Phakathi nokukhulelwa kanye lactation izidakamizwa ethatha, uma inzuzo elindelekile ukuba unina idlula ingozi embungwini. Ngesikhathi sokwelashwa kufanele ayeke ibele.

"Betaxolol": yokusetshenziswa

Inani, ukubuyekezwa, abasebenzi - lawa ezicini ezinhle izidakamizwa ezibangela iziguli ngokuphindaphindiwe ukuze uyikhethe.

Izibhebhe kufanele bedakiwe ekuseni. Kwegazi dragees thatha kanye, eziqala umthamo 10 mg. Uma ngemva kwesonto nomphumela ofiselekayo akuyona etholwe, umthamo senyuselwa 20 ml. Uma umphumela kulindeleke waphinda behluleka ukufinyelela, bese emva kwezinsuku 7-14, ukwandisa umthamo kuya 40 mg.

Iziguli kahle izinso umsebenzi, isebenzisa umshini wezinso, kanye nasebekhulile kufanele asebenzise imithi i inani 5 mg kanye nsuku zonke. Uma kudingeka, umthamo kungenziwa lenyuke zonke izinsuku ezingu-14 ngo-5 mg. Luncoma hhayi idlule umthamo esiphezulu - 20 ml "Betaxolol" ukulungiselela - yokusetshenziswa.

Abstract weluleka ukusebenzisa iso amaconsi ngoba glaucoma. Instillation kumele kwenziwe ngokuqinile e sac conjunctival. A umthamo owodwa ingenye iconsi. Lo mcimbi senzeka kabili ngosuku. Phakathi nenyanga yokuqala ukwelashwa, udokotela kufanele ukuqapha ingcindezi lesiguli intraocular.

side effects

Izimangalo ukuthi kungaholela enqabayo izenzakalo isicelo "Betaxolol" ukulungiselela imfundo manual. Intengo umuthi yeningi, okwenza kube yibo bonke izingxenye sabantu (80 deda. Ukuze 5 ml isitsha futhi ruble 370. Ukuze amaphilisi 30).

Phakathi ukwelashwa "Betaxolol" kungase kube ukukhathala okungamahlalakhona futhi ikhanda, isiyezi, ukozela, ukuqwasha, ukukhathazeka, ukucindezeleka. Encishisiwe okuhlushwa, amaphupho amabi, ukuhhema, ukulahlekelwa amandla okukhumbula, neuralgia, iziyaluyalu vestibular.

Ezinye iziguli ziye zabonakala nokuvusa induku ukwephulwa ukuchama, ubuhlungu ebeleni (e abesifazane), prostatitis, fibrocystic izinguquko webele. Kube ukuqunjelwa, uhudo, nomlomo owomile, isicanucanu, ukuhlanza, ukuqunjelwa, ubuhlungu besisu. Umuthi ngezinye izikhathi kubathinta kabi le ezithathelwanayo wamaphaphu nesifo, dyspnea, okubangela ubuhlungu besifuba, pharyngitis, rhinitis, sinusitis. Fixed bronchospasm, dyspnea, nokuvaleka kwemigudu yokuphefumula.

Phakathi imiphumela emibi futhi sezihlonziwe kanje: bradycardia, hypotension, isilethikusebenza, ukuhluleka kwenhliziyo, leukocytosis, thrombocytopenia purpura kanye nezinye izifo. Engingakusho nje azivamile arthralgia, tendonitis, myalgias.

Kungaba ukuqubuka, Alopecia, komzimba nezinto, eczema, ushintsho isisindo somzimba, erythema, hypothermia, exacerbation psoriasis, hypertrichosis, prurigo.

Isicelo ngeso lehla uyakwazi avuse lacrimation, amehlo omile, angaboni kahle, photophobia, keratitis, erythema, nomzimba angaphandle ukuzwa esweni, ukuzwela corneal, anisocoria futhi photophobia.

Izixwayiso

Lapho Betaxolol yokwelapha izidakamizwa (afundiswe isicelo imininingwane umthamo kanye indlela yokwelashwa) ngokuvamile ushintsho imingcele laboratory. Kungenzeka yokusabela okungamanga ku Dope, titers anda omzimba antinuclear futhi t. D.

Overdose "Betaxolol" izidakamizwa

Yokusetshenziswa (analogs babe ketshezi asebenzayo efanayo futhi nomphumela ofanayo) uncoma kakhulu umthamo. Uma kungenjalo, ungase uhlangane izimpawu ezingemnandi ezifana:

• isiyezi;
• kokunikezwa kwe-uhlelo senhliziyo nemithambo yegazi;
• bronchospasm;
• ukwehlisa igazi glucose;
• imisipha amajaqamba;
• ugoqe.

Kulokhu ukuphathwa classical ababelwe kuzo njengoba kulandela:

• lavage esiswini;
• ukusebenzisa impahla umswakama;
• ukwelashwa lingaze - atropine emthanjeni 1-2 mg beta-agonists, sedatives ejenti, inhliziyo izidakamizwa;
• EHAMBAHAMBA transvenous (unikezwe indaba nje kuphela uma eziphuthumayo).

izinyathelo zokuphepha Siqu

Ukwelashwa okufanele kwenziwe ngaphansi kweso lwezokwelapha. Ekwelapheni ayikwazi uqaphela esigabeni sokuqala-hyperthyroidism futhi kahle kungakhuphula izinga likashukela. Lena ejwayelekile iziguli sikashukela. Encishisiwe izinqubo compensatory izitsha inhliziyo negazi. Awukwazi ukusebenzisa izidakamizwa ngaphambi kokuhlinzwa.

ukusetshenziswa njalo izidakamizwa asebekhulile kwandisa ingozi hypothermia, isimo sengqondo engazinzile, ukuphazamiseka umsebenzi zenhliziyo. Iziguli isifo sezinso futhi isibindi kufanele kube ngaphansi kokuqondisa kukadokotela sika izinsuku ezine zokuqala. Uma umlando Allergic kungenzeka ukwandisa hypersensitivity nokwehlisa nomphumela oqabulayo adrenaline.

Ngesikhathi ukusetshenziswa kwezidakamizwa akuvunyelwe ukuthatha iziphuzo ezidakayo. Wena ubuye abakwazi evele ayeke yokwelapha kanye okudingeka ukwenze kancane kancane, ngokunciphisa umthamo phezu isikhathi esingamasonto amabili. Elikuyalayo abashayeli siqaphe ukusetshenziswa kwemithi "Betaxolol" imfundo manual.

Inani, analogue zomuthi

Uma umuthi anisondelanga, udokotela Ungahlala ukunikela analog, okuvame kuhluke kuphela intengo. Ngakho, amaphilisi kanye lehla "Betaxolol" izindleko mayelana ruble 80-370. Ngu analogue amaphilisi zihlanganisa:

• "Betacam" (Cyprus), kubiza ruble mayelana 300 amaphilisi 20.
• "Lokren" (France), intengo amaphilisi 28 - ruble 600-700, futhi 56 amaphilisi - ruble 1000-1200.

Eye lehla ne betaxolol hydrochloride izidakamizwa esebenzayo ungayithola enye by izidakamizwa ezilandelayo:

• "Betalmik EU" (Slovakia), ama-ruble angu 160-200.
• "Betoptik" (Belgium, e-United States), ruble mayelana 300.
• "Betoptik C" (Belgium, USA), zingakapheli ruble 300.
• "Betoftan" (Romania), ama-ruble angu-200.
• "Ksonef" (India), ama-ruble angu-180.
• "Ksonef BC" (India), ama-ruble angu-150 no.
• "Optibetol" (Poland).

Uthi cishe ukuphumelela ekwelapheni nomfutho wegazi ophezulu izidakamizwa "Betaxolol" imfundo manual. Inani, ukubuyekezwa (analogue ezibizayo, kodwa umphumela ofanayo emzimbeni) - konke lokhu kwaziswa okubekwe ngayo kulesi sihloko.

Ukubukwa iziguli

It uncoma ukusetshenziswa "Betaxolol" Ukwehla kwezinga amehlo yokwelapha imfundo manual. Inani (Izibuyekezo bathi lokhu ingenye izinzuzo izidakamizwa) liphansi, kanye namakhophi ukuze bakwazi ukuthenga cishe noma yikuphi okudinga ukwelashwa. Iziguli eziningi igcizelele ukubekezelelana ezinhle iso amaconsi. Bathi musa abangele engemihle. Umphumela iyabonakala ekupheleni ngesonto lokuqala.

Ngosizo amaphilisi abantu ukulawula umfutho wegazi. Lesi sidakamizwa sisiza ukunciphisa umthwalo phezu kwenhliziyo, ngcono isimo jikelele iziguli. Ezinye disorder ukucindezeleka inqubo ukugaya ezinsukwini zakuqala sokuthatha amaphilisi. Kunabantu esikuye izidakamizwa kuye kwabangela ukuqubuka iguliswa futhi ububomvu esikhumbeni. Othile waphawula nesicanucanu arrhythmia ezinzima.

Iningi izibuyekezo mayelana imithi emihle, iziguli basutha nale yokwelapha.