Ukuchayeka imithi yokubulala izinambuzane kungase kwandise amathuba okuthola i-nomdlavuza wesibindi

Abantu abaye bezwa ukuthi imithi yokubulala izinambuzane, bangase babhekane nenye sengozini enkulu yokuba nomdlavuza wesibindi, kwembula entsha meta-ukuhlaziywa.

Ukuchayeka izibulala-zinambuzane kwakuhambisana nezinga eliphansi angu-71 sengozini enkulu yokuba nomdlavuza wesibindi, ngokusho meta-analysis, okuyinto yethulwa emhlanganweni waminyaka yonke we-American Association for Cancer Research ngo-Ephreli 3, eWashington, DC. Imiphumela angakafakwa eyanyatheliswa ngo iphephabhuku peer-sibuyekezwe.

Yini esiyaziyo mayelana isifo

"Umdlavuza kwesibindi - uhlobo wesithupha umdlavuza nokudlanga emhlabeni futhi wesibili ilandelana, okuvame ukuholela yokufa, kulandela umdlavuza wamaphaphu," - uthi umsunguli walokhu kucwaninga, phambili Hamdi Abdi, umcwaningi kuyo le National Cancer Institute.

Ososayensi bathi izinto ezimbalwa ezimisiwe nomthelela emdlavuzeni isibindi. Phakathi kwabo, izifo ezingelapheki, isib, izifo kwesibindi, kwesibindi ukusebenza okubangwa yileli utshwala. Kodwa abacwaningi bakholelwa ukuthi imithi yokubulala izinambuzane zingase nazo zinendima ethile ekuthuthukiseni lolu hlobo lomdlavuza.

"Ucwaningo eziye kwake kwenziwa izilwane, baye babonisa ngempela ukuthi imithi yokubulala izinambuzane kungabangela umdlavuza kwesibindi kanye, phakathi kokunye, lokhu ukulimala kwe-DNA," - kusho u-Abdi.

Izici meta-analysis

Entsha meta-analysis, abacwaningi wabheka izifundo 16, okuhilela abantu abangaphezu kuka-480 eziyinkulungwane ezivela e-Asia, e-Europe ne-United States. Zonke izifundo kufakwe olunye ulwazi mayelana emazingeni athile zinambuzane nomthelela abahlanganyeli. Futhi ugxile izifundo zendlela leli thonya kungathinta ingozi yokuba uhlobo ezivame kakhulu zomdlavuza isibindi ngokuthi carcinoma hepatocellular. "Abacwaningi baye bathola" imithi yokubulala izinambuzane "ngomqondo ebanzi, kuhlanganise zinambuzane yokubulala ukhula" - Abdi wathi.

Ngokusho imiphumela, umthelela zinambuzane kwakuhambisana nezinga eliphansi angu-71 sengozini enkulu yokuba nomdlavuza wesibindi, kodwa lena akuyona "Inani kakhulu", ngokusho Abdi. ucwaningo okuningi kuyadingeka ukugxila ezithile kwezibulala-zinambuzane umthelela wabo emdlavuzeni isibindi.

Yini ama-akhawunti ukulinganiselwa cwaningo

Okutholakele wokulungiselela, kanye meta-ukuhlaziywa ulinganiselwe. Omunye wabo yokuthi ososayensi bathole izifundo 16 kuphela olwenziwa kuze kube manje, okuyinto ehambelana nohlelo zabo. Lokhu kugcizelela isidingo emikhulu izifundo abazoba okuhloswe ngaso ukuqonda zinambuzane nemikhiqizo imiphumela yabo emzimbeni womuntu.

Enye komkhawulo kwakuwukuthi ezinye izifundo kufakwe meta-ukuhlaziywa bebengenayo idatha okuyiyona inombolo zinambuzane, okuyinto baye bathola ithonya amadoda. Ngokwesibonelo, ucwaningo ezintathu kuphela amazinga compounds elihlobene ne imithi yokubulala izinambuzane egazini abahlanganyeli kulinganiswa. Abanye ancike amaphrofayli.

Ngaphezu kwalokho, ukusetshenziswa ngokweqile kwezibulala-zinambuzane sehluka kakhulu emazweni ahlukahlukene. Ngokwesibonelo, emazweni them they ngokujwayelekile esetshenziswa ezingeni ephakeme kunaleyo emazweni athuthukile, lapho kukhona angaphezu kuka ezinzima imithetho yezokuphepha imikhiqizo, ngokusho World Health Organization.

Ukuhlanganisa emkhatsini umthamo umuthi namaphesenti ukusabela komzimba kuso

Abacwaningi ayenethemba ukuhlanganisa phakathi umthamo futhi impendulo (ijika "umthamo impendulo") ucwaningo olwengeziwe. Ijika "umthamo impendulo" usizo ukucacisa umthamo we ikhemikhali noma ukulungiselela ihlobene ethonyeni lawo. Kulokhu, idatha ku zinambuzane ozochayeka kungenzeka ukuthi umataniswe nokwanda kwentshiseko ezithile e ingozi yokuba nomdlavuza wesibindi.

Okwamanje, kunzima kakhulu ukusho ukuthi yini eyabangela abantu ngokwamanga ukuhlobana phakathi nomdlavuza wesibindi kanye ukusetshenziswa kwezibulala-zinambuzane.