Ukubuyekeza: "Alpha Normiks". Incazelo, ukwakheka kanye yokusetshenziswa zomuthi

Eceleni indoda, futhi izinkulungwane zezigidi zama-bacterium abahlala lapho. Abanye abantu badinga i ukusebenza evamile umzimba, futhi ayikho enye, uma sikubeka kahle, thina ebingayenza nhlobo. amakoloni Lonke kwamagciwane njalo ukuhlola amandla amasosha omzimba womuntu. Ukuze kuliwe kwamagciwane ayingozi okusongela impilo nokuphila kwabantu, ososayensi baye basungula ejenti ekhethekile elwa namagciwane - antibiotic. Ezinye zalezi izidakamizwa zenzelwe ukubhekana eziphilayo ngazinye, nezinye izidakamizwa ebanzi-spectrum (okungenani, ochwepheshe ukushiya izibuyekezo ezinjalo). "Alpha Normiks" - omunye le mithi.

Ukukhishwa

Ukubuyekezwa "Normiks Alpha" lingama isiqondiso esihle, ngoba kuyinto ejenti elwa namagciwane akhiqizwa ngezindlela ezihlukahlukene.

Ezigulini omdala (engaphezu kwengu-12), njengoba umthetho, ochwepheshe bezempilo batusa ukuthola ifomu tablet. Umenzi ukhiqiza uju izindlela ngesimo amaphilisi round ayizindunduma nge umbala pink. Okufakiwe - ibhamuza (amaphilisi 12 ngamunye). Iphakethe umsindo kungenzeka 1 noma 3 amabhamuza.

seziguli ezisencane (eneminyaka engaphansi kwengu-12) ngokuvamile ezinqunyiwe ekwelapheni ukumiswa, okuyinto okulungiselelwe kusukela zithutha (wesibili ukukhululwa ifomu "Alpha Normiks"). I elimbudumbudu ube umbala owolintshi. slurry eliphekiwe inuka cherry futhi ukunambitheka has a iphunga okuhambisanayo. Leli fomu zomuthi is zahlanganiswa ngo amabhodlela (ingilazi Color - amnyama), ngamunye - 5 ml. Sokulinganisa umthamo elungile kuhlanganisiwe indebe wokulinganisa.

Ukwakheka nomuthi

The main ingxenye esebenzayo of Medicine kuyinto rifaximin. Umqulu kwayo okuqukethwe iphilisi ngalinye - 200 mg. Njengoba izingxenye ezengeziwe ukhonza eziningana ezibangela, kuhlanganise propylene glycol futhi glycerol palmitostearate.

Uma umuthi "Alpha Normiks" (isicelo izilinganiso - konke lokhu kuyokwenziwa kuchaziwe ngezansi) inikezwa lomshado ekumisweni e ngomumo asebenziseka isixazululo 5 ml iqukethe 100 mg rifaximin. I nomuthi kuhlanganisa eziningi izingxenye asizayo, kuhlanganise ukunambitheka "Wild Cherry."

pharmacodynamics zomuthi

The main ingxenye esebenzayo (lokhu kuqinisekiswa izilinganiso yezokwelapha) "Normiks Alpha" eziqukethwe-alpha-ifomu, okuyinto kuyivumela ukubophela β-subunit ye-DNA ancike enzyme lwegciwane. Ngamanye amazwi, rifaximin kuvimbela zamagama RNA futhi amaprotheni atholakala emangqamuzaneni virus. Njengoba lesi simanga awushintsheki, umzimba uyafa.

A ezahlukene isinyathelo elwa namagciwane kwenza kube nokwenzeka ukubhekana ngempumelelo nge iningi amagciwane adala izifo ukuthi kumkhathaze ukuthuthukiswa izifo pheshana emathunjini: Gram-negative futhi Gram-HIV, aerobic kanye anaerobic.

Kuthinta "Alpha normiks" yokuthi kakhulu encishisiwe pathogenic emathunjini umthwalo virus. Umuthi ithiya ukukhiqizwa kwe-ammonia amagciwane nezinye izingxube zamakhemikhali anobuthi. Ezigulini isifo sesibindi, ephelezelwa kwezinso e ngokukhishwa kobuthi egazini izinqubo, kubaluleke kakhulu, njenge-ammonia kanye nezinye ubuthi zinengxenye pathogenesis nokuthuthukiswa izimpawu of hepatic encephalopathy.

Futhi Izibuyekezo amaphilisi "Normiks Alpha" yilabo ababezibiza ngongoti libike ukuthi izidakamizwa yezokwelapha kunciphisa ekwandeni eliphezulu amagciwane (ebonwe ukukhula kakhulu nezilwanyana ezincane emathunjini), ukunciphisa yobukhona babo diverticula we ikholoni, kuvimbela ukuvuvukala ngaphakathi komgodlana diverticular. Ngaphezu kwalokho, rifaximin kunciphisa umfutho antigenic (uma zikhona) njalo iyehlisa amathuba yezinkinga ezithathelwanayo ngo imisebenzi kuhlinzwa endaweni colorectal.

Pharmacokinetics

Lapho ethola antibiotic "Normiks Alpha" ku absorbability yayo ingaphansi kuka-1%, mp. E. nomuthi inethonya intracolonic ngoba emathunjini buthelela lokuhlala eliphezulu kakhulu isithako esebenzayo. umthamo zokwelapha aliholeli ukubukeka izidakamizwa e-plasma, noma butholakala lokuhlala aphansi kakhulu.

Ubuningi esiphezulu-antibiotic endleni yabantu abanaleli kutfolakala ngekhatsi 3 izinsuku ukwelashwa nge umthamo wansuku zonke umthamo ingqikithi 800 mg.

Izinkomba ngoba ukusetshenziswa nomuthi elwa namagciwane

Umuthi isetshenziselwa ukwelapha izifo LCD nozwelo rifaximin. Ochwepheshe bezokwelapha linqume ke ukuthola ukukhula okukhulu kakhulu microflora pathogenic emathunjini, uhudo isihambi sika, hepatic encephalopathy futhi divertikuleznyh izifo ayinzima we-colon. Sebenzisa "Normiks Alpha" e nesifo.

Uphenyo odokotela bayakwazisa kahle lokhu-antibiotic e-acute izifo gastro-emathunjini kanye ukuvuvukala njalo emathunjini.

Contra-izinkomba, imiphumela ngokweqile

ezifweni ngamunye ukuze rifaximin, rifamycin noma yimuphi omunye kwenye yezingxenye accessory ye kuyinto ngezizathu anele ngoba ngingayithandi yokwamukela nomuthi. Ngaphezu kwalokho, "Normiks Alpha" (amaphilisi) ukubuyekezwa, nezincazelo imiyalelo iyakwenqabela ematfuba isimiso emathunjini azo zonke izinhlobo, nokuba khona izilonda esiswini.

Ngokuphathelene ngokweqile ibekezelelwe umthamo ke isicelo akuyona ezingaphezu kuka 2400 mg rifaximin overdosing ngaphakathi ngelinye ilanga kungaba kungenzeki. Uma ngasizathu simbe umuthi etholwe lemali kakhulu kokweqa Kunconywa, kubalulekile ukuba lavage esiswini bese uqhubeke ukuthatha izinyathelo ngokuhambisana nokubonisa izimpawu.

side effects

Ngenxa absorbability ongaphakeme (1%) engathandeki imiphumela letindzala njengoba umthetho musa ukuthuthukisa. Okungenani, kusukela iziguli entula i "Alpha Normiks" ukubuyekezwa. Izibuyekezo Real odokotela babike amacala ngabanye ukubonakaliswa okuncane noma okusesilinganisweni omubi ingxenye pheshana emathunjini, ezifana: ukuqunjelwa, isicanucanu, ukuhlanza, colic emathunjini, ubuhlungu besisu. Ezimweni eziningi, zonke lezi ukubonakaliswa babe ngokuzumayo ngaphandle kokuthi ukhansele noma ushintshe umthamo zomuthi.

Ezimweni ezingavamile kakhulu angagcina ukubonakaliswa dermatological, efana urticaria (isifuba). Nge awokuthi, ezinjalo ukungabekezelelani eyashukumisela yokwelapha ngabanye.

Nokho, uma ngaphandle izifo eziyinhloko emathunjini isiguli, ayelapho iyiphi enye yezinkinga ezihambisana impilo ke kungenzeka-high blood pressure, ukuthuthukiswa tachycardia, isiyezi, iphika, nekhanda. Kwangathi ukuthuthukisa imfiva, isilungulela, angioedema.

Uma ngabe uthuthukisa imicimbi ezinzima ezingezinhle, ukubonisana nodokotela wakho liyadingeka.

Imithamo nezindlela yokusetshenziswa

Njengoba kushiwo ngaphambili, amaphilisi kanye granules - amafomu akhona, alinikela abathengi inkampani ye "Alpha Normiks". Izibuyekezo isicelo izidakamizwa, sokuphuza isilinganiso esengeziwe somuthi ngempumelelo futhi indlela yokuphathwa ziyahlukahluka amaphilisi kanye ukumiswa.

Eyokuqala (ifomu tablet) esithathwayo ngomlomo, ngaphandle ukuhlafuna noma ukugqashula. Ezigulini owaphenduka engu-12 ubudala, ngokuvamile ejwayelekile ukwelashwa lwemithi enqunyiwe njalo ngemva kwamahora 8 ukuthatha 1 ithebhulethi, noma njalo kumahora angu 12 - I-2. Isikhathi yokwelapha kunqunywa udokotela, kodwa ngokuvamile kufanele lihlale isikhathi esingaphezulu kwezinsuku 7. Yiqiniso okuphindaphindayo kwamukelekile ukuba afeze emva 1 inyanga.

Ngokuphathelene zithutha, iyokuhlomela ukumiswa lokuqala (ogcwele amanzi kuze kube uphawu lokuqala, umfuma unyakaza ngamandla ke amanzi isipikili kuze kube uphawu olulandelayo) bese ivolumu oyifunayo (isb. E. udokotela esiqokiwe) kukalwa inkomishi wokulinganisa.

OKUVUMELEKILE umthamo ezuziwe ngosuku iziguli omdala (yobudala engaphezu kwengu-12) kungaba isukela 600 kuya 1200 mg zomuthi. Lokhu umkhuba uhambelana ivolumu 10-20 ml at a imvamisa reception izikhathi 2-3 emini. Ezigulini abasebasha (yobudala 6-12) kuvunyelwe nsuku zonke umthamo inani mg 400 kuya ku-800. Ukumiswa esithathwayo kabili ngesikhathi usuku volume of 10-20 ml. Ezigulini abasebasha (lobudala iminyaka 2-6) inani ngelilanga-antibiotic kuyinto mg phakathi 200 kanye 600. It Kunconywa ukuthatha 5-10 ml ngezikhawu izikhathi 2 kuya ku-3 ngosuku. Inkambo zokwelapha akufanele kuhlale isikhathi esingaphezu 1 iviki.

imiyalelo Special

Engingakusho nje ukusetshenziswa eside ye-ejenti elwa namagciwane noma umonakalo we mucosa emathunjini bese, ngenxa yalokho, ukumuncwa nengcosana izidakamizwa kungabangela staining umchamo ngendlela umbala obomvu. Iziguli ngokuvamile zazisho ukushiya izibuyekezo ezinjalo. "Alpha Normiks" iqukethe rifaximin, okuyinto, ngempela, omningi walo ejenti elwa namagciwane yalolu hlobo (rifamycins), has a ngokubomvu orange luhlaza. Kuyinto kule kukhona isizathu sokushintsha ngombala umchamo.

Uma udinga ukuthatha "Normiks Alpha" wayevela esikhathini esesibelethweni yokukhulelwa kanjalo uvunyelwe kuphela ukuswela kakhulu futhi ne ukuqapha ngqo impilo udokotela wesifazane. Kuyefana nasendleleni abesifazane abancelisayo.

Ukuxoxa amanye amalungiselelo yezokwelapha

Ngaleso sikhathi samanje mayelana nokuxhumana neminye imikhiqizo zokwelapha ongoti ukubuyekezwa. "Alpha Normiks" elinesimo ukumuncwa letindzala aphansi kakhulu (ngaphansi kuka 1%), ngakho amathuba iyiphi ukusabela letindzala emazingeni aphansi kakhulu.

Ukubuyekezwa "Normiks Alpha"

Baningi impela iziguli emva kokwelashwa shiya isibuyekezo we antibiotic "Normiks Alpha" ngendlela ukuthi isidakamizwa kahle elisungulwe ekwelapheni izifo emathunjini. Abaningi futhi ubhale ukuthi umuthi kakhulu, ephumelela kakhulu njengendlela yokuthola eziphuthumayo. Ngokusho ochwepheshe bezokwelapha, "Normiks Alpha" - isidakamizwa esinamandla enele. Ngenxa yalesi sizathu, lokhu ngeke kube engadingekile emva ukwelashwa ngemithi elwa namagciwane ukubuyisela microflora evamile esiswini ku baphuze inkambo probiotics.

Ngifuna ukusho ukuthi ukuthatha enjalo elwa namagciwane okufakwa ekudleni enamandla efana "Normiks Alpha", esiyakuqokwa ngudokotela ukuya, ngubani uzohlola isimo sempilo isiguli, ngeke ikhumbule zonke isifo ehlobene isixazululo kuthanda kuphela elungile futhi ngempumelelo.