Myeloma amaningi

myeloma amaningi (isifo Rustitskogo Clair) Akekho omunye ngaphandle isimila umnkantsha, lapho yakhiwa plasma amaseli ukuvuthwa ezahlukene. Incazelo isifo owawukhona ekhulwini XIX. Empeleni, lesi sifo singumbulali kuncike ingxenye omdala sabantu asebekhulile.

Kukholakala ukuthi umphumela myeloma amaningi abe ukuguquka kwezakhi zofuzo B-lymphocyte. Lesi sifo ekwandeni sokugembula plasma amaseli, okuholela ukubhujiswa ketshezi ithambo bone ekubhujisweni. Ngenxa yalokho izinqubo, waphuka njalo futhi ushintshe isimo sabo. Bakhulela izinombolo ezinkulu, plasma cell akhiqiza paraprotein, okubangela ukwanda ngoba aqukethe amaprotheni amaningi egazini. Hyperproteinemia ngokuvamile kubangela isifo sezinso nge ukuthuthukiswa imihlola yokwehluleka kwezinso. Ukubekela eceleni ku tubules, paraprotein kubangela nefrogidroz futhi amyloidosis.
Ukuqhubeka kwesifo kuholela izinguquko sokugembula egazini, hematopoiesis kahle. Esithombeni ungabona igazi kwegazi, umfutho wegazi ophansi kubantu zegazi kanye amangqamuzana amhlophe egazi.

ukubonakaliswa isifo

myeloma amaningi akuyona isikhathi eside izenze wazizwa, futhi isimo lesiguli kungaba kuqhathaniswa egculisayo. Esikhathini esiyiminyaka yokuqala lesi sifo bavele umkhuhlane, ukukhathala, asthenia. Ngokuvamile, uphawu lokuqala oshukumisa ukubona udokotela, kuyinto ubuhlungu beqolo, emgogodleni namathambo, nobuhlungu ivame ukwandisa. izimpawu eminye kungenzeka ukuthi umataniswe nge hematopoiesis kahle (anaemia, thrombocytopenia), ukuthuthukisa oluhambisana syndrome, viscera esivimba amanzi, thromboses. Phakathi izimpawu isifo ezihlobene nokusebenzelana okwandisa esingamahlalakhona kwezinso futhi Hyperproteinemia.

ukuhlola

Esikhathini esiyiminyaka yokuqala kukhona nokwanda egazini erythrocyte sedimentation rate umphumela dysproteinemia. Nge ukuqhubeka inqubo avele kwegazi, kwehle zegazi kanye leukocyte. Ekuhlaziyeni wamaprotheni umchamo ukulahlekelwa waphawula ezinkulu. Lapho ukuhlaziywa kwamakhemikhali igazi kunqunywa ukwanda wamaprotheni Imininingwane. Nge izimpawu ngenxa yezinso - ukwanda creatinine kanye urea, electrolyte ukungalingani.
Sitholakele "myeloma amaningi" kusethelwe esekelwe ngenxa ukuhlaziya umnkantsha amaseli. Lena imisebenzi esemqoka zokuxilonga. Helper indlela ukuba sifeze-X-ray ithambo ukuthola ukukhubazeka bone sengozini, ukukhumuzeka kwamathambo izilonda. Kungcono ukuqhuba proteinogram.

Ukwelashwa nokuvikelwa myeloma amaningi

Uma ukuhlolwa wathola myeloma, ukwelapha lesi sifo kuze kube manje - inkinga kungalungiswanga. Kufanele kube uyazi bungakanani ubude bokuphila iziguli imishanguzo efanele kanye Yiqiniso owendlalekile ka lesi sifo cishe iminyaka emihlanu. Yokwelapha lesi sifo ukusebenzisa imithi okuyinto zivimbela ukuthuthukiswa isimila (cytostatics). Kodwa lezi izidakamizwa isikhathi ekuphileni iziguli kuphela. Ekuqaleni imithi yabo ezinqunyiwe ngemithamo ukushaqeka, ngemuva kokuqeda usuke Yiqiniso yokwelapha yesondlo.

"Prednisolone" lisetshenziswa lihambisana izidakamizwa cytotoxic. Ukusetshenziswa Its kuvimbela ukubhujiswa amathambo kuba nomphumela omuhle begodu kukhula calcium. izinhlobo zemithi athuthukisiwe ezifaka inhlanganisela eziningana izidakamizwa, ngemithamo ehlukene kuye kobukhulu kanye nohlobo myeloma. Imiphumela yokwelashwa Kuhlolwa emva kwezinyanga ezintathu ngemuva kokuqala ngamakhemikhali.

Lapho ukubusa, ukwehluleka kwezinso, kungadinga uhlelo lokwelapha hemodialysis.

Mhlawumbe ukusetshenziswa ukwelashwa ngemisebe. It ezinqunyiwe ekwelapheni elinganiselwe isimila ISIZINDA ise amathambo nezicubu esithambile.