"Metronidazole" - kuyinto-antibiotic noma cha? Yokusetshenziswa nempendulo

Izidakamizwa "metronidazole" - kuyinto-antibiotic noma cha? Impendulo le nkinga yezokwelapha uzothola ngezansi. Futhi ngezinto olunikezwa sihloko uzofunda okuqondiwe ithuluzi esiyingxenye udaba kuba, indlela yokusebenzisa imithi futhi yini ukubaluleka kwayo Pharmacy.

Indlela ukukhiqizwa, emabhokisini kanye nendlela okwakheke ngayo izidakamizwa

Ngaphambi kokuba siphendule lo mbuzo yokuthi kuyini umuthi "metronidazole" (ama-antibiotic noma cha), kufanele usitshele ukuthi izinhlobo ke othize ingatholakala ekhemisi.

Okwamanje izidakamizwa itholakala amafomu alandelayo:

• isixazululo 0.5% ngoba ukumnika. It has a umbala esobala nge Tint umbala ogqamile. Isithako asebenzayo we nomuthi izenzo metronidazole. Edayiswa flasks 100 ml, ibekwe ku amakhadibhodi iphakethe.
• White, amaphilisi round. Ingqikithi asebenzayo buyisidakamizwa metronidazole. Izibhebhe ezibekwe Valium iphakethe planimetric zezinhlamvu eziyishumi. Ngo elinye ibhokisi iphakethe kungaba 1, 2 noma 5 iphakethe.
• suppositories kwesitho sangasese "metronidazole" (amakhandlela). Ukusetshenziswa kwalesi izidakamizwa kumele udokotela. Amakhandlela abe nombala omhlophe (okungase futhi tinge aphuzi) kanye torpedo ukuma. 1 suppository iqukethe into enjalo esebenzayo, njenge-metronidazole. Kuthengiswe izicucu eziyishumi ebhokisini ibhokisi.
• ijeli yesitho sowesifazane sangasese. ingxenye okusebenzayo kwe umuthi metronidazole. Ngo itholakale emakhemisi ngo-30 g we tube ne nokokuyifaka esikhethekile ekuphathweni intravaginal.
• Cream. Uphiko asebenzayo we umuthi metronidazole. I ayatholakala emakhemisi 15 g we tube ukuthi ibekwe ebhokisini amakhadibhodi.
• Ijeli yangaphandle. Isithako asebenzayo we umuthi metronidazole. I ayatholakala emakhemisi 15 g we tube ukuthi ibekwe ebhokisini amakhadibhodi.

izici kwemithi

Yini kuyindlela yokuthola "metronidazole"? Ama-antibiotic noma cha? Udaba phambi kwethu kuyinto izidakamizwa elwa namagciwane kanye ejenti antiprotozoal, nemikhiqizo amahlanu-nitroimidazole.

Umgomo we isinyathelo yalesi izidakamizwa Iwukubuyisela (kwamakhemikhali) ezinhlanu-nitro ezokuthutha amaprotheni intracellular ka anaerobic nezilwanyana ezincane lenyama.

Ngemva yokutakula ezinhlanu-nitro uqala uxhumana DNA amaseli microbial, kanjalo ezivimbela zamagama of acid (nucleic), okwaholela ekubhujisweni amagciwane.

Reception "metronidazole" ingase yabelwe isiguli ukucindezela Trichomonas kanye Ameba dysenteric, futhi baphoqwe anaerobes kanti ezinye izilokazane ezincane igremu-HIV.

Lihambisana ezifana i-antibiotic "amoxicillin", umuthi liveza umsebenzi omuhle ngokumelene Helicobacter pylori.

Akunakwenzeka ukuba uqaphele iqiniso lokuthi izidakamizwa esebenzayo kwaleli thuluzi kukhona bangakhathaleli muntu anaerobic facultative nezinto ezincane eziphilayo aerobic. Nokho, ukuba khona flora okuxubile (aerobic kanye anaerobic) izidakamizwa esebenzayo izenzo synergistically nge antibiotic okuyizinto ngempumelelo ngokumelene ezivamile aerobic.

Kufanele kuphawulwe ukuthi lokhu kusho kwandisa ukuzwela izimila emisebeni, futhi kubangela sensitization yotshwala (isb has disulfiramopodobnyh isinyathelo).

I pharmacokinetics zomuthi

izidakamizwa "metronidazole" inqobo ugxile? Yokusetshenziswa, odokotela real mayelana izidakamizwa bathi izidakamizwa has a Ukungena ikhono kuqhathaniswa eliphezulu. Ngemuva kwesicelo isithako esebenzayo ngokushesha (cishe ihora elilodwa) ifinyelela lokuhlala amagciwane kuzo zonke izinto eziwuketshezi futhi iningi ezicutshini zomzimba womuntu, kuhlanganise izitho zangaphakathi ezifana izinso, amaphaphu isikhumba, isibindi, ubuchopho, cerebrospinal fluid, ngamathe, Bile, amniotic fluid, isitho sangasese somuntu wesifazane imfihlo ingaphakathi abscesses, ubisi lwebele futhi isidoda. Kufanele kuqashelwe ukuthi le isici kwamanje kwalesi izidakamizwa kalula kweqa gazi ebuchosheni futhi umgoqo esinomhlapho.

Ingxenye-ukuphila we nomuthi (kumsebenzi evamile kwesibindi) amahora mayelana 8. Uma isiguli ukulimala kwesibindi oludakayo, lesi silinganiso kwandisa ngokuphawulekayo (kufika ku 18 amahora).

Kuboniswa izidakamizwa ngokusebenzisa izinso (cishe 80%), kanye ngokusebenzisa emathunjini (u-20%).

izinkomba izindlela

Kwezinye izimo, ukulungiswa nesineke "metronidazole" angabelwa? Analogue lokhu ejenti kanye izidakamizwa ngokwayo ibe izinkomba ezilandelayo:

• amebiasis extraintestinal, kuhlanganise isibindi ithumba (amebic);
• amebiasis emathunjini (noma okuthiwa uhudo amoebic) ;
• lezinkinobho Trichomonas;
• trichomoniasis;
• izifo eziningi, kuhlanganise amalunga omzimba, amathambo, isimiso sezinzwa;
• urethritis Trichomonas;
• meningitis;
• izifo protozoal;
• i-pneumonia,
• ubuchopho ithumba;
• empyema;
• endocarditis webhaktheriya;
• wamaphaphu ithumba;
• ukutheleleka kwezitho zangasese (abscesses amaqanda, amashubhu fallopian, endometritis, isitho sangasese somuntu wesifazane egumbini ukutheleleka);
• sepsis;
• nesifo pseudomembranous ezihambisana nokusetshenziswa ejenti elwa namagciwane;
• izifo besisu (isibindi ithumba noma peritonitis);
• kolwelwesi isilonda noma duodenum 12 (noma esiswini), ehambisana ne-khona Helicobacter pylori;
• ukwelashwa ngemisebe kweziguli izimila (ezazisetshenziswa njengomhlatshelo radiosensitizing ejenti);
• zokuvimbela izinkinga ngemva kokuhlinzwa (ukuhlinzwa ensimini adrectal, ikholoni, ukuhlinzwa izifo zabesifazane, appendectomy).

Izimo ukusetshenziswa kwezidakamizwa

Kwezinye izimo, kungenzeka ingasetshenziswa yokukhalaza "metronidazole"? Yokusetshenziswa, ochwepheshe zangempela aqukethe uhlu olandelayo Izimo:

• lesion (uhlamvu organic) CNS kuhlanganise nesifo sokuwa;
• leukopenia, kuhlanganise umlando;
• esingamahlalakhona hepatic (ekumisweni ebulilini);
• sokukhulelwa (ikakhulukazi senyanga 1st);
• Hypersensitivity kuya izingxenye;
• lactation.

Nomuthi "metronidazole": isitatimende

Amazwana ngalokhu imithi, sizobe ukwethula kancane okunye. Manje ukunitshela indlela izidakamizwa okufanele zithathwe.

amaphilisi

• Lapho amebiasis - 1.5 g ngelanga 3 ngemithamo ahlukaniswe kulo lonke isonto.
• Lapho giardiasis - of 750-1000 mg ngelanga 3 ngemithamo ahlukaniswe izinsuku 5 (kuphela ngemva kokuthatha ukudla).
• Uma trichomoniasis kwabobulili bubuhle (lezinkinobho futhi urethritis) - 2 g umthamo owodwa noma uhlobo oluthile lokwelapha Yiqiniso izinsuku 10 250 mg kabili ngelanga (inkambo iyaphindwa ngemva kwamasonto 4-7).
• Uma trichomoniasis unayo ubulili eqinile (urethritis) - 2 g umthamo owodwa noma uhlobo oluthile lokwelapha Yiqiniso izinsuku 10 250 mg kabili ngelanga (inkambo iyaphindwa ngemva kwamasonto 4-7).
• Lapho lezinkinobho nonspecific - 500 mg kabili ngosuku lweviki
• Ngaphansi anaerobic izifo - 1-1.5 g ngosuku.

Injection

ekuphathweni esicutshini ekulungisweni liboniswa kuphela ezifweni ezimbi, kanye kunjalo uma kungekho kungenzeka eyamukelayo kusho ngaphakathi.

A umthamo owodwa kuyinto mg 500. Isikhawu phakathi imijovo akumele ibe ngaphansi kuka-8 amahora. Isikhathi yokwelapha kunqunywa ngamunye. Umkhawulo lemali nsuku zonke izidakamizwa akufanele kube iminyaka engaphezu kwengu-4

Gel kanye ukhilimu Ingaphandle

kufanele ngisebenzisa kanjani nokulungiselela yangaphandle "metronidazole"? Isenzo zomuthi zizosebenza kakhulu uma isetshenziswa ngesikhathi esifanayo ne-antibiotic ezivamile.

Gel noma ukhilimu lisetshenziswa ungqimba elincanyana phezu kwesikhumba kabili ngosuku (ngemuva kokuthola futhi ngaphambi kokulala). Isikhathi kwelashwa amasonto 3-7. Gel kanye ukhilimu kungenziwa alternated njalo ngemva kwamahora angu-12.

ijeli yesitho sowesifazane sangasese

ukusetshenziswa Intravaginal. I Isikali kumele kube 5, ijeli efiselekayo Faka kabili nsuku zonke (emva uvuka futhi ngaphambi kokulala) emalanga la -5.

suppositories sowesifazane sangasese

Kusho esetshenziswa vaginally. Ikhandlela injected ezijulile sangasese ekupheleni ezicijile. Ukuze ekwelapheni Trichomonas lezinkinobho abeke suppository kabili nsuku zonke izinsuku ezingu-10. Ukuze ekwelapheni lezinkinobho nonspecific zisebenzisa 1 suppository kabili nsuku zonke ngeviki.

Nomuthi "metronidazole" - kuyinto-antibiotic noma cha?

Lo mbuzo uvame kakhulu nesithakazelo kulabo babekade bemiswe ukuba wathi nomuthi. Njengoba kushiwo ngenhla, nomuthi "metronidazole" kuyinto ukulungiselela okuyinto okulungiselelwe synthetically, it has a spectrum ezibanzi umsebenzi. Ngakho-ke, umbuzo, izazi zithi leli thuluzi akuyona i-antibiotic. Ngemva imithi elwa namagciwane kukhona izinto zemvelo ethathwe isikhunta ethize. Kepha metronidazole, emvelweni, ingekho. It is etholwe izindlela amakhemikhali.

Analogs futhi intengo izidakamizwa

Kungakanani buyisidakamizwa "metronidazole"? Analogs izimali yena imithi nendleko hhayi eliphezulu kakhulu. Kuye ukuma ukukhululwa lo muthi ungase ube amanani ahlukene. Ngokwesilinganiso, ke uyahluka 15-150 ruble Russian.

Okwamanje, kunezinhlobo lenqwaba analogs yalesi izidakamizwa. Amathuluzi abalandelayo ethandwa kakhulu: "Trykhopol", "metronidazole-akos", "Metronidal", "Batsimeks", "Trihosept", "Metrolaker", "Deflamon", "Metroseptol", "Clione", "Trihobrol", "Metrovagin "" Rozeks "," imitha "," Siptrogil "," Metrogil "," Metron "," Metroksan "," Orvagil "," Rozamet "," ifulege ", njalo njalo.

Uphenyo imithi

Kukhona okuningi okubuyayo ngalokhu nokulungiselela. Iziguli eziningi zithi lokhu kusho ikhambi fast kakhulu izifo eziningi, kuhlanganise kolwelwesi futhi izilonda esiswini. Nokho, kufanele kuphawulwe ukuthi inombolo ezincane iziguli esekhala side effects, abonakala ngokushesha ngemva ukungenisa. Iziguli ku ukunambitheka metallic emlonyeni, ubuthakathaka, isiyezi, ukucobeka, izinhlungu zekhanda ezinamandla, ukukhathala, ukucanuzela kwenhliziyo, ubuhlungu esiswini, ukuhlanza kanye nokunye.