"Laferobion" e ampoules: mathupha. "Laferobion" e ampoules njengoba uhlobo?

Ukukhuthaza izivikeli mzimba ukwakha isidakamizwa ngesisekelo interferon, esesikhundleni immunomodulatory, umsebenzi elwa namagciwane kanye antitumor. Engena phakathi umzimba, ketshezi asebenzayo sibopha ukuthi la mangqamuzana cell aqondile futhi kubangela izimpendulo intracellular.

Lakhiwa "Biopharma" (Ukraine), "Laferobion" ukulungiselela izingane kanye nabantu abadala angathuthukisa amasosha omzimba ukuba sibhekane ngokuphumelelayo izifo ezibangelwa amagciwane kanye ezibangelwa amagciwane, ukulwa nomdlavuza.

Zonke izinhlobo Isikali

Umuthi itholakala ifomu:

• suppositories rectal 3,000 ayizinkulungwane 1000 izinkulungwane, 500 amawaka, izinkulungwane 150 IU zahlanganiswa ngo amabhamuza 10, 5 noma 3 izingcezu ....;
• powder lyophilized for abayizinkulungwane 100, izinkulungwane 1000, 5000 noma 3000 eyizinkulungwane eziyinkulungwane IU in vials plastic kwelinye iphakethe iqukethe 10 flasks ....;
• ... A powder lyophilised obuyizinkulungwane 6000, futhi 18 ayizinkulungwane 9000 ayizinkulungwane 000 IU amabhodlela epulasitiki, equkethwe kwelinye iphakethe 1 ibhodlela;
• acinene powder 500 th. noma izinkulungwane 100. IU e umfuma, okuyinto kuhlinzekelwe cap-weThrojani.

Lapho belungela ukuya khona "Laferobion" e ampoules Umhlahlandlela uqukethe ulwazi mayelana nokuba khona amaphakethe nomunye noma ampoules 5 ml amanzi ahlanzekile ukuze dilution.

Incazelo ukulungiselela

Powder-lyophilizate njengoba ezimhlophe hygroscopic mass ukungena nakwamanye amazwe esetshenziswa ukulungiselela isixazululo umjovo.

Powder-lyophilisate ngesimo isisindo eyohlobo ukukhanya, isetshenziselwa ukulungiswa isixazululo acinene.

izakhiwo Hygroscopic abonise kokubili ifomu ampoule "Laferobion" ukulungiselela. Iziqondiso ezichazwa etholwe emva dilution ketshezi njengamafutha esobala, isixazululo ezinemibala kancane. ifomu acinene isetshenziselwa ephefumula, umjovo kanye instillation. Ikhambi komjovo iqondiswa intramuscularly, phansi kwesikhumba futhi ngemithambo yegazi dropwise.

Ukwakheka powder

Isithako asebenzayo zomuthi "Laferobion" e ampoules imfundo ubiza interferon womuntu isakhi sokuzakhela. Kuyinto efanayo alpha-2b-interferon futhi kuhlelwe umqondo amaseli leukocyte igazi zithonywa igciwane interferonogen. I nomuthi ubukisa umphumela immunomodulatory futhi elwa namagciwane, okuyinto alibonisi ubuthi at yokuvuma ngokusebenzisa izitho zokuphefumula.

Inani zezinombolo e isihloko izidakamizwa likhombisa inani lemithi asebenzayo iyunithi ngamazwe (IU). Ngokwesibonelo, lesi sidakamizwa "Laferobion 100000" e ampoules for nokulungisa isixazululo umjovo iqukethe e isakhiwo 10 ⁵ IU of isakhi sokuzakhela -alpha -2b-interferon womuntu. izingxenye Asizayo zihlanganisa i-sodium chloride, dextran, i-potassium dihydrogenphosphate, disodium phosphate dodecahydrate.

Ngo ukwakheka suppositories rectal "Laferobion 150000" equkethwe 150 ayizinkulungwane. IU isakhi sokuzakhela-alpha womuntu -2b-interferon. Ngu izingxenye ngasebenzi zihlanganisa ascorbic acid, tocopherol acetate, amanoni okuqinile.

powder acinene iqukethe 100 th. noma 500 ayizinkulungwane. IU isakhi sokuzakhela-alpha womuntu -2b-interferon. Lokhu kufakwa i-sodium chloride, dextran 70, i-potassium dihydrogen phosphate, disodium phosphate dodecahydrate ukudala inhlanganisela esitebeleni.

Kanjani nomuthi

Isenzo "Laferobion" zomuthi in vials imfundo kubangela izakhiwo zemvelo leukocyte interferon. Kuyinto lowo ikhombisa namagciwane, anticancer futhi immunomodulatory umsebenzi futhi akuyona anobuthi.

Indima interferon ekwelapheni izifo eziningi ezihlobene kwethulwa eziningi ukusabela kwamakhemikhali okuholela amaprotheni zamagama, okusithiyayo lwempi kwezicubu umsebenzi immunomodulatory phagocytic, futhi makrofagotsitarnyh lymphocyte amaseli, okusithiyayo yokuzalana ezibangelwa amagciwane kanye nezinye amaseli angavamile.

ukwelashwa olunzulu izifo

On imithi "Laferobion" imfundo kuhlanganisa izinkomba ukusetshenziswa, ihlukaniswe ngezigaba ezintathu eziyinhloko. Eyokuqala yalezi kukhona izifo ezibangwa izifo amagciwane.

Lesi sidakamizwa sisiza ukuba ubhekane nezingcindezi igciwane herpes, kuhlanganise causative ejenti ye samabhamuza ezithweni zangasese, herpes we ezimise okwama-tile iso, izilonda abandayo esikhumbeni, ukutheleleka nge Papillomavirus womuntu warts zangasese, warts, inhlamba, keratoacanthoma.

Isetshenziselwa ukusha kwesibindi kohlobo ezingamahlalakhona B, D, C omdala kanye ebuntwaneni acute hepatitis C no-B, ezithwalwa encephalitis amafomu meningeal ekwelapheni isimo isibindi cirrhotic lihambisana hemosorption futhi plasmapheresis.

I nomuthi "Laferobion" isetshenziselwa ukwelapha ezinganeni kwesibindi okungamahlalakhona kanye D, C, B, izimpawu isifo Hodgkin sika, wegazi, izimila okuqinile, acute sokusha kwesibindi kohlobo C, perinatal hepatitis C noma B, nge-meningitis aseptic kubangelwa enterovirus.

Umuthi ngempumelelo isimo omdala ngoba umkhuhlane ne-acute izifo zokuphefumula viral, nge yezinkinga ngesimo superinfection.

Medicine "Laferobion" kungenziwa ukwenziwa ezinganeni ezizalwa ngaphambi kwesikhathi kanye nezinsana zabo samakhaza, acute izifo zokuphefumula viral, sepsis, meningitis, isifo fetus, okuhlanganisa izimpawu ka-herpes, candidiasis visceral, chlamydia, CMV, futhi enterovirus ukutheleleka, ureaplasmosis, mycoplasma.

Ukulungiswa kuyinto abesifazane ofanele futhi ekhulelwe izifo urogenital elihlobene ne-chlamydia, Human Papillomavirus ukutheleleka, ureaplazmozom, CMV ukutheleleka, vaginosis webhaktheriya, trichomoniasis, mycoplasmosis, samabhamuza ezithweni zangasese, candidiasis lwesitho sangasese sowesifazane, gardnerellezom, bronchopneumonia, pyelonephritis, sibi zokuphefumula igciwane lohlobo, izifo zamaphaphu okungamahlalakhona, isifo sokusha kwesibindi kohlobo viral C futhi B.

ukwelashwa Comprehensive in Oncology

Iqembu izinkomba yesibili zihlanganisa ukwelashwa komdlavuza libhekene melanoma isikhumba namehlo, izimila kwezitho ahlukahlukene (amaqanda, izinso, kwesinye, nezindlala mammary), myeloma amaningi, Sarcoma Kaposi nezinye izimila ebulalayo.

ukwelashwa Kuhlanganiswe ezinye izifo

Ukulungiselela "Laferobion" (ampoules) izingane elisetshenziswa izifo ezifana insulini sikashukela engaphansi mellitus, isifuba somoya, glomerulonephritis, pyelonephritis, dysbiosis emathunjini, kolwelwesi okungamahlalakhona, duodenitis, ukuvuvukala okungalapheki ikholoni, mumps kobukhulu obuhlukahlukene, idiphtheria zendawo.

Ingasetshenziselwa therapy lihambisana engamahlongandlebe rheumatoid arthritis, i-multiple sclerosis, wendlala imisuka ehlukahlukene, ukuxakeka ukonakala ngemva kokuhlinzwa.

Ukusebenzisa isixazululo acinene

"Laferobion" kudingekile ukulungisa isixazululo powder ngaphambi kokusebenzisa umkhiqizo wakho. Indlela ukuzalela lyophilisate - imfundo ngokushesha.

Kusebenta yokwelapha inerferonom lizophakama lapho besanda kuqala lesi sifo nge ukubonakala izimpawu zokuqala. Sibi zokuphefumula izifo ezibangelwa amagciwane, kuhlanganise umkhuhlane, izifo ezibangelwa amagciwane kanye ezibangelwa amagciwane ziphathwa ephefumula, umjovo noma acinene instillation "Laferobion" isixazululo.

Lapho sigcwalisa izidakamizwa Kunconywa ukuba asebenzise 5 amaconsi ikhala ngalinye, okuhambelana 0.25 ml ikhambi, umsebenzi okuyinto kusuka 50 kuya 100 IU of interferon tysyach. Le nqubo wenziwa nge imvamisa amahora mayelana 1-2 izikhathi 6 ngosuku izinsuku 3.

Ukuze ephefumula ngomlomo noma izindima acinene usebenzisa i inhaler ultrasonic. It is batheleka isixazululo okulungiselelwe kusuka okuqukethwe izitsha eziyisikhombisa ezintathu, lapho powder ziyoncibilika 5 ml amanzi abilisiwe noma inzalo. Le nqubo Kwenziwa kabili ngosuku.

Ukwelashwa izinsana kuze kube inyanga 1 ukuchitha turundas acinene wetted nge izidakamizwa lwenkomo olufakwe amanzi "Laferobion", yethulwe ngamunye ngamunye e ikhala ngalinye imizuzu engu-15. Lapho sigcwalisa isetshenziswa izinsana ezinjalo ezizalwa umthamo kusuka ayizinkulungwane 50. Isixazululo IU ingezwe 3 amaconsi ngamunye ikhala izikhathi 4-6 ngosuku. Isikhathi kwelashwa kwezinsuku 3-5.

Njengoba isilinganiso izifo ukuze ugweme ukugula sibi zokuphefumula igciwane lohlobo ngesikhathi umqedazwe noma ukuxoxa isiguli, umthamo ngokuvamile esetshenziselwa kusuka 50 kuya 100 IU tysyach 1 ml, 5 amathonsi imithi, okuhambelana 0.25 ml, kabili ngosuku ngomuthi umehluko emahoreni angu-6.

Indlela yokutshala powder acinene

Buyekeza isikhathi ezingaphephile kufanele safaka noma ijovwe "Laferobion" isixazululo ukulungiselela (ampoules). Njengoba isitshalo powder ukuthola isixazululo nge umsebenzi 50 th. Noma 100 ayizinkulungwane. IU, ezichazwe imiyalelo. Thatha okuqukethwe omunye isitsha futhi ziyoncibilika 1.2 ml amanzi ahlanzekile futhi oyinyumba, kanti isitsha kufanele ayonyakaziswa kahle.

Ukusebenzisa ikhambi umjovo

isixazululo Injection ngoba esicutshini, ongama, intradermal, intraperitoneal, ukusetshenziswa intravesical (ampoules) "Laferobion" ukulungiselela. Indlela ukutshala kahle lyophilisate futhi ngaphansi kwaziphi izifo ukusebenzisa, kungatholakala imiyalelo. Ngokuvamile, i-powder kwelinye isitsha buhlanjululwe 1 ml amanzi nemijovo.

Ukushayela ekwelapheni amafomu okukhulu ukusha kwesibindi kohlobo B ayizinkulungwane 1,000 IU :. kabili ngosuku izinsuku 5 kuqala, bese esilinganayo kanye ngosuku okulandelayo izinsuku 5. Lapho ukwelashwa ukwehluleka ragela phambili uthule obuyizinkulungwane 1000. IU izikhathi 4 emavikini amabili. Ezigabeni zokuqala icteric esiteji umphumela izidakamizwa ephawuleka kakhulu ukwedlula ukuze zisetshenziswe kamuva.

Isikimu nokwelashwa kwesibindi kohlobo B okungamahlalakhona ifomu :. Esimeni isigaba asebenzayo obuyizinkulungwane 3000-6000 IU kathathu ezinsukwini ezingu-7, inkambo sihlala 24 amasonto. Eemvekeni ezi-12 i-HbeAg titer, izidakamizwa wagumbuqela nge kahle enganele.

Isikimu yokwelashwa amafomu njalo hepatitis C :. IU eziphindwe kazinkulungwane 3,000 amathathu zokugcina ezingu-7, isikhathi yokwelapha of mayelana 24 amasonto. Ngemva kwamasonto 4, okuqukethwe Alat kunqunywa yayo ezingeni eliphezulu umthamo ukusetshenziswa 6000 th. IU. Eemvekeni ezi-12 hlola isinyathelo izidakamizwa, futhi ukungabi khona ashukumisayo ukuphathwa omuhle zohlelo.

Isimiso ukwelashwa nge encephalitis ezithwalwa :. ayizinkulungwane 1000-3000 IU kabili ngosuku izinsuku ezingu-10, bese kuba ayizinkulungwane 1000-3000 IU ne periodichnoostyu efanayo ezinsukwini ezilandelayo ezingu-10 ..

Icebo ekwelapheni izifo oncological: ethola Ukweqiwa esiphezulu isikhathi eside. Okungalapheki myeloid wegazi -. Ayizinkulungwane 9,000 IU ngosuku ngaphambi ukuqala ukuthethelelwa, kulandele ayizinkulungwane 9,000 IU kathathu kulezi zinyanga ezingu-7 ..

Lymphocytic wegazi - ayizinkulungwane 3000 IU ngosuku ngaphambi ukuqala ukuthethelelwa, kulandele inombolo efanayo kathathu kulezi zinyanga ezingu-7 ..

Kwezinso cell carcinoma -. 18 ayizinkulungwane 000 IU kathathu kulezi zinyanga ezingu-7.

Ukusebenzisa i-ukumnika

izidakamizwa "Laferobion" isetshenziselwa ukumnika abaphathi. Kanjani sokutshala ukusebenzisa ukuvuza, kungatholakala imiyalelo.

Ngaphambi isixazululo ukumnika ne ukuvuza interferon imizuzu engu-30 i solution isotonic ka-sodium chloride-0.9%, izinga kokuphathwa 200 ml ngehora.

Lungiselela isixazululo ukumnika "Laferobion" by Ukuqedwa umthamo wayefisa 1 ml amanzi nemijovo. Ngemva isixazululo eyinhloko ixubene isixazululo 50 ml i-sodium isotonic chloride 0.9%. Ready dropwise uketshezi nokulungiselela iqondiswa ngemithambo yegazi imizuzu engu-30 bese futhi uqhubeke iconsa imizuzu 10 isixazululo isotonic ka-sodium chloride, 0.9% ngesikhathi 200 ml ngehora.

Ukusetshenziswa amakhandlela ukwelapha ezinganeni

Izingane preterm neonates futhi ingelashwa nge suppository rectal "Laferobion" in umthamo 150 ayizinkulungwane. IU. Ngosuku ukubeka 1 suppository kabili ngezikhawu amahora 12, izinsuku ezingu-5 inkambo yokwelapha.

Lapho yebhaktheriya ezinsaneni zisebenzisa suppository 1 umthamo 15 eziyinkulungwane. IU kathathu ngosuku. Nge 4 izinyanga ka nokushintsha kokudla nokufakwa kungandisa ofika ku-500 eziyinkulungwane. IU kabili nsuku zonke phakathi kwezinye izinto, kusukela ezinyangeni ezingu-6, kabili ngosuku iqondiswa for amakhandlela ezimbili.

side effects

imiphumela emibi lesi sidakamizwa "Laferobion" (e ampules) Umsebenzisi Ukudluliselwa uhlelo umzimba. I Lesi sifo siphatha kakhulu emiphumeleni ohlelweni imithi: kwegazi, senhliziyo, endocrine, wokugaya ukudla, zemisipha, wethukile futhi zokuzala.

Isimo jikelele umzimba ungathi umkhuhlane, okuyinto livezwa ubuhlungu emisipheni nasemalungeni, ubuhlungu obuhlabayo emehlweni, ikhanda, asthenia, Ukugodola.

Uma ungeke ukwazi ukusebenzisa

"Laferobion 100000" imithi e ampoules Umhlahlandlela alikukhuthazi ku:

• yokungezwani komzimba-alpha interferon nezinye izingxenye;
• ukusha kwesibindi kohlobo sokuhlasela kwamasosha omzimba;
• decompensated isifo sesibindi;
• creatinine imvume ngaphansi kuka-50 ml ngomzuzu;
• elithwala umoya-mpilo ephansi.

izindleko

Abaningi linqume izidakamizwa "Laferobion" (ampoules). Intengo elilodwa pack of 10 izitsha eziyisikhombisa ngesikhathi umthamo ayizinkulungwane 100. IU acinene powder kuyoba ruble mayelana 96. Ebizayo ekwelashweni imijovo. Ngoba kufike umuntu mumbe umfuma ayizinkulungwane 1,000 IU kuyodingeka bakhokhe ruble mayelana 320. omama abasakhula Yiqiniso, kuyoba intengo ezithakazelisayo futhi ehlukene :. "Laferobion" izingane amakhandlela nge umthamo ayizinkulungwane 150 IU, 5 izingcezu iphakethe ngalinye libiza ama-ruble angu cishe ngo-530.