Izidakamizwa "Prestarium": Izibuyekezo imithi

Ukulungiselela "Prestarium" - umuthi esetshenziswa ekwelashweni kwe- izifo zenhliziyo , futhi isetshenziswa ukunciphisa umfutho wegazi. Kuyatholakala ku-nomuthi "Prestarium" Izibuyekezo ukuqinisekisa ukusebenza yayo ekwelapheni isifo senhliziyo nomfutho wegazi ophezulu kanye. isithako wayo esebenzayo perindopril kokuba okusheshayo vasodilatory isinyathelo ngokunciphisa ukwabiwa angiotensin II, okuyinto constricts imithambo yegazi. Ngo ukusetshenziswa letindzala zomuthi kubuyiselwa kuyaqina emikhulu izitsha ophakeme, futhi ukwehla kwesokunxele ventricular hypertrophy.

In iziguli nesifo senhliziyo izikhathi eziningi kunciphisa kumiswa subendocardial collagen ukulungiselela "Prestarium". Izimpendulo futhi abonisa normalizing imiphumela yako izinqubo umzimba e myocytes inhliziyo. Lesi sidakamizwa kusiza ukuphungula Layisha futhi afterload wenhliziyo, usimamise kusebenta kwato evamile. Ngaphansi isenzo "Prestarium" kusho iconsi ingcindezi kwenzeka ngesikhathi ukugcwaliswa we ventricles, esehlisa jikelele umthwalo precardiac. Lesi sidakamizwa kuyinto inhibitor ukuthi kunciphisa ishayela nekwenyusa nezimo wenhliziyo ukwandisa umsebenzi ngokomzimba.

Ngekusetjentiswa eside zomuthi "Prestarium" (izibuyekezo siliqinisekise) akuphazamisi okuqukethwe potassium igazi izinso ukusebenza. umphumela Hypotensive ye-ejenti ifinyelela umphumela esiphezulu ngemuva kwamahora amahlanu futhi ihlala usuku lonke. Ngemva kwenyanga, ukuphathwa ehlelekile kuholela sinjalo okuqhubekayo wegazi ukuthi iqhubeka isikhathi eside. Ukuhoxiswa ekupheleni ukwamukelwa kusho "Prestarium" is hhayi waphawula.

Iziguli isifo cerebrovascular ngubani njalo wasebenzisa isidakamizwa "Prestarium" Ukubuyekezwa kwesokunxele kuphela ngokubonga, okusikisela ukuthi ukwelashwa nolaka lesi sakhiwo izikhathi eziningi kunciphisa ingozi yokushaywa unhlangothi futhi yisiphi isifo esindayo zenhliziyo. Perindopril akunamthelela ushintsho glomerular filtration isilinganiso we nezinso, okwandisa ukugeleza kwegazi kuzo. Lesi sidakamizwa ingxenye esebenzayo ngokushesha angena igazi ngemva kokuphathwa ngomlomo. esiphezulu plasma lokuhlushwa kwalo kwenzeka phakathi kwehora ngemuva kokuthatha imithi. Perindopril 20% is ibe le perindoprilat iyasebenza, futhi bioavailability Imininingwane kuyinto 70%.

I nomuthi "Prestarium combi" itholakala izibhebhe ukuma elongate, ifilimu-camera, kokuba umbala omhlophe. Omunye tablet iqukethe 5 mg perindopril arginine elihambisana 3,395 mg perindopril futhi indapamide 1.25mg. Njengoba izinto asizayo kunezelwa izibhebhe: glycerol, sodium isitashi glycolate, Silicon dioxide, i-magnesium stearate, monogidrad lactose, ama-titanium dioxide, macrogol futhi hypromellose. Ngaphambi kokuthatha lesi imithi edinga udokotela ukugunyazwa ukusetshenziswa kwaso.

Kukhona Izimo eziningi ukuthola ukulungiselela "Prestarium" (5 mg) kwakuyilawa: sokukhulelwa, ngesikhathi lactation, encephalopathy hepatic, ukuzwela anda nokulungiselela ingxenye, hypokalemia, ukwehluleka kwezinso, angioedema. Nakuba kokuthatha lesi izidakamizwa, kufanele sisinakisisa kwedivayisi yayo nezinye izidakamizwa.