Incazelo isifo: Huntington

Huntington kuyinto esingamahlalakhona okuqhubekayo lezinceku isifo neurodegenerative, okuyinto kuhambisana zengqondo kanye motor. Imbangela eyinhloko zokugula kuyinto isakhi sofuzo esinephutha okuyinto enomthelela ukubukeka amaseli yezinzwa amaprotheni sokugembula yokwephula evamile umzimba nomthofu intracellular ukuvela kwezinso kwamakhemikhali ebuchosheni. Nge isifo siqhubeka ngokuhamba kwesikhathi, futhi izimpawu ziba kakhulu.

Lapho lesi sifo amangqamuzana obuchopho zanqwabelana inombolo ye-gamma-aminobutyric acid yanda, nezinzwa cranial amaseli luyanda nensimbi ivolumu exchange kuyaphazamiseka Dopamine.

Syndrome nesineke Huntington sika budluliselwe kusuka umzali ngubani othwala isakhi sofuzo mpofu ngenxa autosomal evelele. Lapho isifo ingozi umzali chorea ukubonakaliswa sifo ingane amaphesenti amahlanu. Izimpawu yokuqala isifo avele abaneminyaka ephakathi kwengu-30-40.

Lesi sifo kwenzeka 3-7 amakesi likhulu lamawaka. Indoda phakathi baseYurophu, ezinye izizwe ingenye iyagula in a million.

Huntington: izimpawu

Ekuqaleni lesi sifo bavele isici chorea hyperkinesis, non-Rhythmic, okusheshayo, ukunyakaza azitholakali kalula. Uma eqala iziguli azikwazi ukucindezela ukubonakaliswa idatha at intando, by ukuthuthukiswa sifo ikhono enjalo buthakathaka. Konginitivnye kanye nokugula ngengqondo ngokuvamile ziqala ukuqaphela emva kwesikhathi esithize lapho kuqala lesi sifo.

Lapho izifo kubantu kuyehla intelligence komqondo asathuthuka.

Phakathi ukuqhubeka kwesifo, iziguli nobunzima obukhulu uma ufuna ukwenza ezinye ukunyakaza okunenjongo. Nasi sibonelo: Ngesikhatsi umuntu uhamba yenza ukuthinta ngokweqile, ingabe-sit-ups, yenza ubuso, staggers ngenkathi ushayela. In iziguli ngenkulumo nzima, encishisiwe imisipha ithoni, kancane kancane komqondo. Umuntu angakwazi ukubamba isikhathi eside ebhekwa ngezindlela isikhundla (ukwenza isibhakela, ukulungisa entweni).

Kungenzeka endocrine kanye disorder neurotrophic.

Huntington: Ihlahlubo

Sifo kusekelwe izimpawu zokwelashwa kanye nomlando nomndeni. Ngo inqubo yocwaningo kanye ukucacisa ngokukhukhumala kwentamo izinguquko atrophic ebuchosheni ekhanda. Lapho kuhlolwa chorea ehlukanisiwe Alzheimer Parkinson, ugcunsula, encephalitis, ebuchosheni, ukuthi babe nezimpawu ezifanayo.

Huntington: Ukwelashwa

Namuhla, azikho izindlela zokwelapha lesi sifo, esizokwenza ukuba aqede zonke izenzo Huntington Syndrome noma ayeke inchubekelembili yayo. Ezimweni eziningi, ukwelashwa lingaze. Ukucindezela hyperkinesis, iziguli ukuthatha imithi ethize.

Lapho ukucindezeleka kwenzeka, imithi antidepressant kanye ukwelashwa kwengqondo. Ukuze iwenze ube lula isimo lesiguli ezinqunyiwe antipsychotic (neuroleptics) imithi, zinhlungu, sympathomimetics, nemithi yokunciphisa ukucindezeleka.

Lesi sifo nzima ukubonakaliswa ezithathelwanayo kungenzeka nenshisekelo nenyumoniya.

Isilinganiso bempilo zabantu abaphethwe isifo iminyaka engu-15 kusukela ngo-izimpawu zokuqala zokugula. Ngokujwayelekile uma ukubonakaliswa eyinhloko zimpawu sangaphambili yobudala zokugula iqhubeka ngokushesha. Ngakho, uma isaziso izimpawu zokuqala yokugula ngo iziguli kuze kube iminyaka engu-20, ukuphila kwabo kwesikhathi sokuphila kubalulekile kwengu-8. Ngokuvamile ngife ngenxa yezinkinga chorea ezihlobene. Omunye nanhlanu iziguli wazibulala.