I-resistant ovarian syndrome: izimpawu, ukwelashwa, ukuvimbela

Ukuphikisa i-ovarian syndrome kuyindlela encane efundiswa ngayo yokukhubazeka kwesifazane. Ngokuvamile lesi sifo sibonakala eminyakeni engu-25-35. Efaniswa ukungabikho okwesikhashana kokuya esikhathini ngezinga eliphakeme lamahomoni ase-gonadotropic we-pituitary gland.

Incazelo

Okubalulekile kwalokhu kugula kungenxa yokuthi ama-ovaries ayeka ukufeza umsebenzi wabo ngokushesha. Ngokuvame ukuthi lesi sifo siqhubeka futhi siphela ngokuya esikhathini. Ubungqayizivele besifo sokukhubazeka kubonakala ekungabhubhi kanye nokungabikho komjikelezo wokuya esikhathini. Ngesikhathi sesifo, izinhlobo ezahlukene ze-amenorrhea zivame ukukhula. Kule nkathi kunezinga eliphakeme le- hormone ye- gonadotropic emgodini we- pituitary, ngoba umzimba usazama ukuqala ama-ovari. Kodwa-ke, aqala ukusebenza, njengoba inani elincane leprogesterone ne-estrogen linikezwa. Isikhathi sokuqala inkinga yaqala ukukhuluma ngo-1959, abososayensi bachaza izibonakaliso zesifo se-ovaries esimelana nayo. Kodwa nokho lesi sihloko asikaqondakali kahle, futhi izizathu zalokho kwenzeke namanje azichaziwe ngokuphelele.

Izinhlobo

Ezincwadini zokubhekisela zezokwelapha azikho ukuhlukaniswa okucacile kwalesi sifo. Nakuba abanye ochwepheshe beveza izindlela ezintathu zokuthuthukisa lesi sifo:

1. I-Genetic predisposition of defects kulezi zixhobo ze-follicular.
2. Imvelo yokuzimela - ngesikhathi sokukhiqizwa kwama-antibody, ukuzwela kwe-follicle-stimulating hormone receptors kuvinjelwe.
3. Uma usebenzisa izidakamizwa ze-cytotoxic kanye nama-immunosuppressants.

Izimpawu

I-syndrome yama-ovarie emelana nayo ingavame ukunqunywa kusuka ezifweni ezibalwe:

• Izibalo eziphezulu ze-LH (i-hormone yokuqondisa i-hormone) ne-FSH (i-homlicle-stimulating hormone) ne-estradiol ephansi;
• Amenorrhea - ukungabikho kokuya esikhathini;
• Ukususwa kwe-mucosa yangasese kanye ne-vulva;
• Ama-ovari ngeenamba ezinkulu ze-follicles ezinosayizi ojwayelekile kanye ne-endometrium encane yombeletho;
• Ukudluliswa kwezifo ezinzima zegciwane nokucindezeleka;
• Ukuya esikhathini kuqala ukungajwayelekile, bese kuphele ngokuphelele.

Ukuthuthukiswa kwesifo ngokuvamile kuvame emva kweminyaka engu-5-10 kusukela emjikelezweni wokuqala. Konke ukuhlola okushiwo ukuthi ukushisa okushisayo ekhanda kubonakala ebusuku nasebusuku. Imizwa ebuhlungu emlonyeni ibonakala ngokuzenzekelayo, ngaphandle kwezizathu zalokhu. Ngokuvamile, abesifazane abane-syndrome yama-ovari anqabile banenkinga ebuhlungu yokuya esikhathini nesimo se-postpartum.

Lapho isiguli siza ukubona udokotela ngezikhalazo zesifo esibuhlungu phansi nokungabikho kokuya esikhathini emva kokutheleleka kwegciwane, ukuhlolwa nokuhlolwa okuvame ukukhombisa ukuthi wathatha i-sulfanilamides ngobuningi obukhulu, okungabangela ukubonakala kwesifo.

Izimbangela

Namuhla izici ezithonya ukwakhiwa kwezilwane azizange zifundwe ngokugcwele. Kodwa kukhona inkolelo yokuthi cishe umthombo wesifo yizinguquko zofuzo ku-node ye-receptor ye-follicle. Iningi lososayensi lithi i-syndrome yama-ovarie emelana nawo, izimpawu zazo ezihlukile futhi eziyinkimbinkimbi, ngokuvamile zithinta izifo ezinjalo:

• Ubuningi;
• Yenza ngokuzenzakalelayo i-thyroiditis (ukuvuvukala kwegciwane le-thyroid);
• I-Myasthenia gravis (ubunzima bemisipha nokukhathala);
• Isifo sikashukela sikhona;
• Purpura ye-Thrombocytopenic;
• Ukutheleleka ngegciwane lesandulela ngculaza (okuvame ukuvuthwa);
• I-autoimmune i-anemia.

Izizathu eziyinhloko zokuthuthukiswa zihlanganisa lezi zinto ezilandelayo:

• I-irradiation nge-oncology;
• Ukusetshenziswa kwama-immunosuppressants kanye ne-cytostatics;
• Ukungenelela kokusebenza kuma-ovari.

Ngaphezu kwakho konke lokhu, isifo sofuba se-pulmonary kanye ne-sarcoidosis kubangelwa ukulimala kwezicubu zomzimba, okuvame ukuholela ekuthuthukiseni ukugula. Lesi sifo singakwazi futhi ukuthwala uhlamvu lwezakhi zofuzo futhi sibonakale ngemva kokucindezeleka okukhulu kanye nokuqhaqhaqhaqhaza kwemizwa njalo.

Izifo

I-symptomatology yalesi sifo ihlobene eduze nezifo ezifana ne-gonadal dyscrasia ne-ovarian malnutrition. Ngakho-ke, kuphela ukutadisha okuphelele kwezikhalazo kanye nedatha evela e laboratory yezinhlolo zomtholampilo kunqunywa ukutholakala kwezifo. Ngokuvamile, ngesikhathi sokuhlolwa kokuqala, umuntu angaqaphela umphumela obuthakathaka "umfundi," ukukhathazeka ngohlobo lwe-fibrocystic, ukuchithwa kwengxenye yangaphakathi ye-mucosa ye-vulva ne-vagin kanye ne-hypermia yayo. Nge-echography, i-laparoscopy nokuhlolwa kwegazi, ukuhla okuncane kakhulu ngobukhulu besibeletho kubonakala. Ukuze kuqinisekiswe isifo samanqamu omelana nawo, odokotela banikeza i-biopsy ye-epididymis. Ukuhlolwa kwe-histological kwenziwa ukuze kutholakale amaseli we-parenteral ne-pyramidal. Uma uhlolwa i-hormonal, ungabeka izinga lika-LH ne-FSH e-plasma yegazi, evame ukuphakama futhi ayihambisani nokujwayelekile. I-concentration ephansi ye-estradiol itholakala. Ukunakwa okukhethekile kubhalwa ukuvivinywa kwe-hormone, kuphawulwe ukuthi ukuhlolwa kokuqala kubonisa i-gestogen eningi kakhulu, futhi ku-negative - okulandelayo.

Ukwelapha

Imithi yokwelashwa ivame ukubhekana nenkinga enjenge-syndrome yama-ovari omelana nawo. Ukwelashwa kuhlale kungenangqondo, ngoba isimo sokuqala kwesifo asiqondiswanga ngokugcwele. Ngokujwayelekile i-HRT inqunywe (i-hormone therapy substitution) nokulungiswa kokuntuleka kwe-estrogen. Isisekelo senqubo ukubuyiswa komjikelezo wokuya esikhathini nokunciphisa izinga lamahomoni e-gonadotropic.

Ngokuvamile, odokotela banquma izidakamizwa ezinjengokuthi "Trieskvens", "Feston", "Klimen", "Premella-cycle", "Klimonorm", "Divina", "Klimodien", "Livial" ne "Cliogest". Ngenxa yemvelo yenkambo, isiguli kumele sithole i-ultrasound ye-pelvis njalo ngonyaka. Ukulawula ukuhlaziywa kwegazi, i-lipoproteins ne-cholesterol kusiza ukwakha nokwazi ukuqala kwesigaba esisha sokwelashwa. Ngenxa yezifundo ze-densitometric, i-osteoporosis ingafakwa ngaphandle.

Kanye nokwelapha izidakamizwa kuhlangene kahle ne-non-yendabuko:

• Ukuphatha i-ultraphoonophoresis yangaphakathi ne-celiac;
• Indawo yokuphumula;
• Ukwakhiwa kwe-ovary octan receptors;
• Ukwamukelwa kwe-vitamin E.

Idatha emiphumeleni yokwelashwa okunjalo iyamangalisa kakhulu. Kodwa odokotela basho ukunyuka kwenani lokucasha kokuya esikhathini kanye ne-follicles, i-LH ne-FSH iyasebenza. I-estrogens iqala ukuphakama egazini. Emva kokubuyiselwa kokuya esikhathini, ukuvuthwa okujwayelekile ngokuvamile akukwenzeka, kanti isiguli singakwazi ukubeletha ingane nge-IVF (in vitro fertilization).

Kuze kube manje, ukubeletha komzimba akufundile kahle ukuthi kungani kune-syndrome yama-ovarie omelana nawo. I-hypergonadotropic amenorrhea yisifo esibi kakhulu, futhi okwamanje asikho uhlu oluyinhloko lwezincomo zokuvimbela nokwelashwa kwayo. Okulungile kakhulu kubhekwa ukuthi akubandakanyi izimo ezimbi futhi unyaka ngamunye ukuhlolwa, ikakhulukazi uma kukhona ukwephulwa komjikelezo wokuya esikhathini.

Imithi yendabuko

Kuvame ukusetshenziselwa ukwelashwa kokuvimbela. Kunconywa ukuthatha njalo u-vitamin E, etholakala emikhiqizweni enjengama-hazelnuts, amantongomane, ahlume ukolweni nama-walnuts. Ukubuyisela umjikelezo wokuya esikhathini kuzosiza ingxenye ye-lecithin, etholakala emigqumeni, i-caviar ne-cauliflower, futhi njengoba kuyaziwa, ukungabi khona kwakhe kubonisa ukuthi i-syndrome ye-ovaries emelana nayo. Ukwelashwa ngamakhambi omuntu, kanye nama-phytopreparations ngokugcwele ahambisana nomthelela wokwelapha.

Ngokuvamile lezi ziqoqo ze-herbal, ezinezakhiwo ezibukeka kahle futhi zilawula kahle umjikelezo:

1. Ukuze ulungise ukubunjwa, udinga ukuxuba amagremu angu-30 amaqabunga e-peppermint, izimpande ze-valerian nama-40 amagremu we-chamomile. Umthamo olungiselelwe uthululwa ngamanzi abilayo kanti ingilazi eyodwa isetshenziswe kusihlwa nakusasa.
2. Ukumnika amajikijolo okuthiwa i-viburnum ne-blackberry kusiza ama-ovari, ngoba lokhu kudinga ukuthatha izibuko ezimbalwa ngosuku.
3. Ukuthuthukisa umjikelezo wokuya esikhathini kudliwa yi-pair of cloves of garlic.

Ukungenzi lutho

Isigaba sokuqala sokwelashwa kuhlanganisa ukujwayela kwesimiso se-endocrine, okungukuthi, ukulungiswa kwegciwane le-thyroid, umsebenzi we-grenade futhi ukwelashwa kwesifo sikashukela.

Khona-ke kuyadingeka ukuqhuba:

• I-Spermogram yomlingani (izikhathi ezintathu zamaviki angu-7), ukuze kungabandakanyi isici sokungazalwa komuntu;
• I-Echosalpigography (ukuzimisela kobuciko be-tublopian tubes);
• Ukuhlolwa kwe-postcoital - ukuqinisekisa ukungahambi kahle kwe-immunological infertility;
• I-hysteroscopy (hlola i-intrauterine pathology).

Okulandelayo, asetshenziswa izidakamizwa eziqala ukugqugquzela i-follicles, bese iqhubeka nokuthola ukubonakala kwe-ovulation. I-syndrome yama-ovari omelana nokukhulelwa kuyahambisana, njengoba ku-60-70% amacala, ukungabi namandla kunganqotshwa ngosizo lwezidakamizwa.

Ukuvimbela

Kusukela kuze kube yimanje, imithi yanamuhla ayizange ifunde ngokugcwele inqubo yokubonakala kwesifo, kunzima kakhulu ukuthola izinyathelo ezithile ezingasiza ekuvimbeleni kwayo. Nakuba ochwepheshe abaningi basikisela, uma kungenzeka, ukungasebenzisi ukudakwa kwezidakamizwa nokungabhekiseli ekuvezweni kwemisebe. Kunconywa ukuthi kuholele indlela yokuphila enempilo futhi uphathe izifo ze-gynecological ngesikhathi, ngakho-ke ayikho i-syndrome yama-ovarie anomelana nawo.

Ukuvimbela kungenxa yokuthi ngezingcindezi ezincane kakhulu emjikelezweni wesimiso, udinga ukuvakashela udokotela bese uthola zonke izivivinyo ezidingekayo. Lokhu kuzosiza ekuvimbeleni ukuthuthukiswa kwezinhlobonhlobo ze-pathologies nokugcina impilo yabesifazane.

Imiphumela kanye nokubikezela

Ingcindezi eyinhloko ukuphulwa komjikelezo nokungabi nabantwana, okuyinto enzima ngokwanele yokwelapha. Futhi ingozi yokubunjwa kwangaphambili kwezifo ezihlobene nobudala ikhuphuka, njengoba kunesifo se-estrogens futhi kunethuba lokuthuthukisa izicubu ezimbi zesisu.

I-prognosis iyakhuthaza, futhi umsebenzi wokuya esikhathini uvame ukubuya.