"I-Allopurinol": ama-analogs, isenzo, ama-contraindications

Amathambo amaningi abhekene nokwandiswa kwe-urate kanye nokufakwa kwawo kwezicubu. "I-Allopurinol" yisidakamizwa esinciphisa inombolo yabo. Ngingayisebenzisa nini le mithi futhi ngingayifaka kanjani?

Isenzo

Isidakamizwa sisiza ukunciphisa umsebenzi we-xanthine oxidase, okungukuthi, uyayivimbela. Ngenxa yalokho, ukubunjwa kwe-urate kuncishisiwe, ngoba i-enzyme iyadingeka ukuguqula i-hypoxanthine ibe yi-xanthine futhi iphinde iguqulwe ibe i-uric acid. Yingakho ama-salts alo mzimba engakhiwa ngokweqile futhi engafakwa ezinhlobonhlobo. Ngakho, "i-Allopurinol" iyasebenza. Ama-analogs abhalwe ngezansi anendlela efanayo.

Isiphi isidakamizwa esetshenziswayo?

"I-Allopurinol" iyadingeka ezifweni ezihlobene nokulahleka komzimba. Leli qembu lihlanganisa ikakhulukazi izifo ze-urinary system, ezihambisana ne-hyperuricemia, kodwa phakathi kwezinkomba ezikhona nezinye izifo. Isibonelo, ukwakheka ngokweqile kwemikhawulo kubonakala ngokubola kwe-nucleotide, okuvame ukuba nemvelaphi yokwelapha. Isidakamizwa sinqunywe kulezi zimo ezilandelayo:

• Urolithiasis ihambisana nokubunjwa kwe-urate;
• I-Gout;
• Ukwelashwa kwesisu kusho;
• Ukwelapha isikhathi eside nge-corticosteroids;
• I-toxicosis ephazamisayo;
• I-pathology ye-purine metabolism;
• I-Psoriasis;
• Cedar Lesch-Nyhena.

Ngalesi sifo, odokotela banquma "i-Allopurinol", okufanayo. Intengo yezidakamizwa ihluka.

Ingabe wonke umuntu angayisebenzisa imithi?

Isidakamizwa sinomthelela omkhulu ezinkambisweni zemethamo, ngakho-ke akukho ngaphandle kokuphikisana. Ungayithathi phambi kwe-hypersensitivity, okuzoholela ekukhuleni kwezimo ezibuhlungu. Futhi, lesi sidakamizwa siyaphikisana nokuhluleka kwenkunzi, esesiteji se-azotemia; Ukukhulelwa nokukhwabanisa, idiopathic hemochromatosis, ukubonakaliswa okunamandla kwe-gout (ngaphambi kokungeniswa kufanele ume ukuhlasela).

Lapho uneminyaka engu-14 ubudala, umuthi unqunyelwe kuphela uma kunezibonakaliso eziphawulekayo, ngenkathi ukuthatha imithi kufanele ilawulwe ngokuqinile ngudokotela. Ngaphezu kwalokho, kufanele kuthathwe ngokuqapha uma kukhona ukuhluleka kwenhliziyo, isifo somfutho wegazi ophezulu noma isifo sikashukela. Lolu hlu luvame kakhulu kumuthi we-Allopurinol. I-Analogues nayo inezinkomba. Mayelana nemibono efana nomuthi, sizoxoxa ngokuhamba kwesikhathi.

I-Allopurinol: imiyalelo yokusetshenziswa

Ama-Analog azoxoxwa ngezansi, kodwa manje ake sikhulume ngokuthi singathatha kanjani i- "Allopurinol". Ukusetshenziswa kwezidakamizwa kuvunyelwe kuphela ngaphansi kokuqondiswa kochwepheshe, njengoba kudingeke ukuba ukhethe ukulinganisa komuntu ngamunye. Phakathi nesikhathi sokwelashwa kuyadingeka ukuqapha izinga le-uric acid ku-serum. Isibalo sesithako esisebenzayo sincike ekungenikeni kwesifo. Ngenkambo encane, kuvame ukushiwo 100-200 mg ngosuku, futhi isilinganiso semilinganiso senyuke kabili. I-pathologies enesidingo ngokuvamile idinga 700-900 mg ngosuku. Kuzingane, umthamo ukhethwe ngokusekelwe kwesisindo somzimba. Imiphumela yomuthi iphawulwe amahora angu-24-48 ngemva kokuphathwa. Amanani ayi-ruble angu-120 amaphilisi angu-30.

Ukuhlanganiswa nezinye izinto

Esinye isici esingavumeli ukuzithokozisa, kuba khona kokuphendula okuphathelene nokuphikisana lapho kuhlangene nemithi ethile. "I-Allopurinol" ayikwazi ukuthathwa ngesikhathi esisodwa nge "Azathioprine", "Methotrexate", "Theophylline", i-mercaptopurine, njengoba ubuhlungu besimanje buyanda. Futhi, lesi sidakamizwa sikwazi ukuthuthukisa ikhono le-anticoagulant lama- anticoagulants angaqondile nomphumela we-hypoglycemic we- "Chlorpropamide." Ukuhlanganiswa "ne-Amoxicillin" ne-"Ampicillin" kungabangela ukuqala kwezikhukhula zesikhumba. Ngaphambi kokuqokwa, thola ukuthi yimaphi amalungiselelo isiguli esithathayo, bese uqhubeka ukwelashwa.

"Allopurinol": ama-analogues, ama-synonyms

Ukulungiswa kunemifanekiso elandelayo: "i-Allopurinol-Aegis", "i-Sanfipurol", i- "Purinol", "i-Allpol". Isenzo sezidakamizwa sifana nokho, kepha banokuhlukile. Akunakwenzeka njalo ukuthenga "i-Allopurinol". Ama-analogues, intengo engase ibe ngaphansi, ukuxazulula inkinga.

Alopron

Isidakamizwa singasetshenziswa kwabesifazane abakhulelwe, kodwa kuphela uma kunezinkomba eziqinile zokwelashwa. Kulesi simo, umthamo kufanele ukhethwe ngokucophelela. Uma kunesidingo sokumisela izidakamizwa ngesikhathi sokudla, kubalulekile ukuyeka ukudla nokushintsha okwesikhashana ekudleni okufakelwayo. Ukwelapha kuqala ngokuqokwa kwesilinganiso esinciphile - 100 mg. Ngemva kwamasonto 1-3, yanda ibe ngu-300 mg. Ezinganeni, umthamo ubalwa ngokusekelwe kwesisindo somzimba.

"I-Allopurinol-Aegis"

Umuthi, ngokungafani ne-hero ye-athikili, ungasetshenziswa cishe ngaphandle kwemingcele ebuntwaneni. Kubekiwe ngaphakathi, umthamo ukhethwe ngokucabangela izici ezithile. Ngokuvamile, kudingeke ukuthi 200-400 mg ngosuku, kodwa umthamo unganyuswa uma kunesidingo. Izingane kufanele zisebenzise inani elincane lomuthi, kanti ingxenye yansuku zonke ihlukaniswe ngamanani amathathu. Izindleko ziyi-ruby 100-110.

Amazinga aphakanyisiwe e- uric acid egazini agcwele ukufakwa kwezingxenyeni zomchamo, ikakhulukazi ezithintekile izinso. Ukuvimbela imiphumela enjalo, ukusetshenziswa kwezidakamizwa zokungcolisa umzimba, lapho "i-Allopurinol" ibhekisela khona (izilinganiso ezingasetshenziswa) zingasiza.