Hypovarianism, Izimpawu kanye Ukwelashwa

Ngaphansi hypofunction wesibeletho kusho eside emitholampilo ukuthi kuhlanganisa izifo ukuthi kuhluke omsakazo kanye pathogenesis. Bonke babe izimpawu ezifanayo nokungathuthuki ngokobulili. Lezi zihlanganisa ukungabi nenzalo, hypoplasia, amenorrhea, hypoestrogenism nokungondleki kwesibeletho futhi ezikhiqiza amaqanda.

Kunezinhlobo eziningi hypofunction eyinhloko. Primary, oyinhloko, ifomu emitholampilo ye sifo menopause kwesikhathi. Ngokuvamile kwenzeka abesifazane abaneminyaka engama 35. Etiology lesi sifo ingafeza lukhulu ahlukahlukene enqabayo yizici zemvelo. Imbangela sifo kungaba kwezakhi, yofuzo, iziyaluyalu sokuhlasela kwamasosha omzimba e ezikhiqiza amaqanda.

hypofunction wesibeletho kungenzeka ngokumelene isizinda imisebenzi normal menstrual futhi okuzala. It kubonakala ngesimo ukushisa komzimba, amenorrhea, ukujuluka anda, ukukhathala, ubuthakathaka, ubuhlungu enhliziyweni kanye nenhloko, ukunciphisa ukusebenza kahle. Phakathi nesenzakalo ngalesi sifo kuchazwa: usayizi encishisiwe kwesibeletho futhi ezikhiqiza amaqanda, lokuhlala eliphansi estrogens futhi prolactin, akukho follicle nemizimba ophuzi, ephakeme follicle Ugqozi hormone luteinizing egazini. Lokhu hypovarianism has impatho enjalo: isicelo hormone (i-estrogen bese estrogen-progestin). Ukwelapha i-hormone Ithuthukisa kakhulu isimo iziguli, ngakho ekusunguleni uphethwe kubalulekile ukuqala ukwelashwa ngokushesha.

Angawodwa (zesibili) hypovarianism zokukhukhumala, iziyaluyalu eziphilayo nemisebenzi yokusetshenziswa ekusebenzeni kwenqubo hypothalamic-pituitary kukhona izinhlobo ezibalulekile emitholampilo leso siyaluyalu. Naphezu kweqiniso lokuthi ezikhiqiza amaqanda waphawula inombolo ejwayelekile ka follicle, abazi kwenzeke inqubo nokuvuthwa. Ukuze isimo esinjalo libhekene: ukungondleki amenorrhea samabanga aphansi noma, lesizalo futhi hypoplasia wesibeletho, gipoestrogeniya. Lokhu hypovarianism ngokuvamile kwenzeka ku ngemuva okuqukethwe ejwayelekile FSH futhi luteinizing i-hormone egazini.

Kukhona polycystic syndrome esibelethweni. Lesi sifo cishe 3% abesifazane abasha. ukuphazamiseka enjalo ebonakala ukukhiqizwa okweqa androgens (adrenal kanye esibelethweni), ukwehluleka neuropathy umzimba wabo. Kanye nalezi zici kunqunywa i esengeziwe luteinizing hormone, lokuhlala evamile noma ongaphakeme ka FSH, amazinga ephakeme igazi prolactin. Lokhu hypovarianism, izimpawu libhekene pseudohermaphroditism ukuthuthukiswa, okuyiwona libhekene hyperandrogenism, hypertrophy clitoral, amenorrhea, ukungazali, anovulation kanye induna ezinzima.

Esinye isizathu, okungase kwenzeke ngenxa hypofunction ezikhiqiza amaqanda kungenzeka virilizing izimila wesibeletho. Isimila cells e ezikhiqiza amaqanda yakha esiningi ngokweqile testosterone, dehydroepiandrosterone futhi androstenedione, okuyizinto hormone ocansini besilisa. ukubonakaliswa Clinical yesifo kukhona ukungabi khona ukuya esikhathini okungajwayelekile kokuya esikhathini Liwubala (oligoopsomenoreya), acyclic lesizalo ukopha. Lesi sifo libhekene izimpawu of Alopecia, hirsutism, ushona kwezwi, ukwakheka uhlobo umzimba wesilisa, ukwakheka pseudohermaphroditism, hypertrophy we clitoris.

Uma kukhona hypovarianism, impatho kunikezwa emva ucwaningo olunzulu. Ngo ukwakheka izimila eyenziwa nokwelashwa ngamakhemikhali, emisebeni nokususwa kuhlinzwa yesimila. iziyaluyalu kwama-hormone ziphathwa emva ukuxilongwa okujuli- amahomoni ahlukahlukene.