Conjugated linoleic acid: isicelo kanye nemiphumela engemihle. Conjugated linoleic acid: Izibuyekezo

Muva nje ungezwa eziningi ulwazi mayelana nezinzuzo Izithako zokudla, okuyizinto ingxenye yesigaba sokubhekela izimo linoleic acid conjugated. Kuyini linoleic, ngisho conjugated ngaphezulu, bambalwa abantu bazi. Ongelutho igama ucishe ecacile ku-chemistry imithi "acid". Ukuthenga imikhiqizo kanye nemikhiqizo equkethe lokhu isithako, iningi lethu ziqondiswa ukwaziswa kufundiswe futhi ubheke phambili Imiphumela imilingo. Zama ukuqonda lokho okungalindelwa kusukela lo mkhiqizo.

linoleic acid

Ukuze ukuphila okunempilo ukusebenza evamile zonke kwezitho zomzimba kuyadingeka ukuba isidumbu kubalulekile fatty acid, okuhlanganisa linoleic. Kuyinto uchungechunge komugqa ama-athomu carbon, okuyinto zibaliwe ukuze kube lula biochemists. Phakathi 9 no-10, futhi phakathi kwama-athomu 12 nele-13 liqukethe eyodwa substituents zokuxhumana. carbons Ubuningi abahlukanise, ekuvimbeleni lokhu kuxhuma ukugxambukela nomunye ngaphandle izakhiwo ketshezi bazimisele. Conjugated linoleic acid ingatholakala njengenhlangano Lesisemkhatsini inqubo ukuguqulwa elula linoleic acid ukuze stearic. Bobathathu ibalulekile ngoba umzimba womuntu. Ngaphandle acid okunamafutha, ikakhulukazi linoleic, emzimbeni esephula izinqubo umzimba ahlupheke esimiso senhliziyo nemithambo yegazi, kwegazi, isifo sokuqina kwemithambo yegazi Kutfutfukisa siba sibi amandla kubo bonke kwezicubu. Abaningi linoleic acid ivuliwe esakhiweni Ulwelwesi lwamangqamuzana egazi emzimbeni womuntu. Ngakho-ke kubaluleke ukudla okune-ke.

Kuyini conjugated linoleic acid

Kule ndaba, isomer-amasekela yokushintsha indawo. Omunye wabo itholakala phakathi 6th futhi carbons 7th, kanye nezinye phakathi wesi-8 kanye 9th. Le ndawo eduze kubenza bakwazi ukuthonya nomunye, kanye olulodwa khulula isibopho carbon athomu, imi phakathi kwabo. Umehluko wesibili e ezihlobene acid indawo ezimbili ukuxhumana substituents ngemva kwendiza yochungechunge. Ngo linoleic elula iyona cis-ifomu, okungukuthi, ngakolunye uhlangothi, futhi kungase kube conjugated trans-ifomu, okungukuthi ezahlukene. Ngenxa yalaba umehluko ebonakala ingasho lutho conjugated linoleic acid ozuza izakhiwo ezintsha. Ikakhulu, ongenza imisebenzi emibili - ukucindezela umsebenzi kokubili amafutha asegazini Transporter kumaseli, Esilula lipase, futhi ngesikhathi esifanayo ukuthuthukisa nokwahlukana ekhona fat umzimba, kuyilapho linoleic abavamile, kunalokho, kunomthelela ekuqongeleleni fat. Omunye umehluko ukuthusa Kuyaphawuleka ukuthi linoleic acid oyingqayizivele ikhuthaza cholesterol ezifweni ukuba namachibi ukusabela, futhi conjugated ke kuzole.

Ukuvulwa kwe-ososayensi American

Nakuba izinto zobuchwepheshe zamuva, conjugated linoleic acid (CLA) uvulekele muva. Eminyakeni 1979-1980 iqembu lososayensi e-University of Texas olwenziwa eziningi izifundo umphumela ukudla ezahlukene ukuphila umzimba. Michael Peyriz, ngaleso sikhathi owayese umsizi, ngaphawula ukuthi wosa uyosisebenzisa ngendlela engaphezu kwevamile kuvimbela ukuguquka kwezakhi zofuzo kuyi-DNA imisipha amaseli izilwane. Kwatholakala ukuthi lokhu impahla baye bathola ketshezi inyama. Uphenyo wavula kanye nezinye izakhiwo ewusizo timphawu omusha, ikakhulukazi ikhono zinqanda ukukhula izimila anomdlavuza. Lokhu kwaba negalelo eqinile lapho kutadishwa izinqubo kwamakhemikhali ekusebenzeni conjugated linoleic acid ukugqanyiswa.

izakhiwo awusizo

Kulesi sigaba, izifundo wembula ukuthi conjugated linoleic acid (CLA) uyakwazi:

• ukuphuthumisa lokugayeka kokudla emzimbeni;
• ukusiza ukwandisa yemisipha;
• cholesterol ephansi;
• kuncishiswe ingozi sikashukela insulin;
• ngcono ukungatheleleki;
• nethonya eliyinzuzo zokunciphisa amacala yokungezwani komzimba ukudla.

CLA amalungiselelo zivimbela inqubo ekuqongeleleni fat, ikakhulukazi peritoneum (visceral). Lolu hlobo of fat ukuthi kungaba thatha izitsha isibindi, inhliziyo negazi, kuyingozi kakhulu futhi ngokuvamile uholela ekubeni isifo senhliziyo, unhlangothi, thrombosis nezinye izinkathazo. CLA kwandisa nozwela imisipha amaseli insulin, amafutha ngakho kanye glucose ngokuya idlule ulwelwesi, ngaphandle kokulibala "zigciniwe." Ngenxa yalokho, iphesenti fat enciphile futhi yemisipha iyakhula.

izifundo Laboratory futhi ucwaningo

Naphezu kweqiniso lokuthi izakhiwo eziningi ezimangalisayo uye conjugated linoleic acid, ukubuyekezwa odokotela nabacwaningi kukhona kuyadida ngakho. Lokhu kungenxa yokuthi kulesi sigaba ukusetshenziswa kwezidakamizwa, ucwaningo kakhulu ziye eyenziwa izilwane. Ngokwesibonelo, ngo-amagundane wapha inyama okugazingiwe nsuku zonke, kakhulu ivinjiwe isimila kumiswa inqubo. Yiqiniso, akunakwenzeka ukuthola ngasiphi isigaba kwenzeka - ngasekuqaleni, okuqhubekayo noma ukugcina lapho umdlavuza iqala ukuba iyakhula. Kukhona kucatshangwa ukuthi izidakamizwa isebenza kuzo zonke ezintathu. Ngaphezu kwalokho, amagundane, nezinkukhu CLA kakhulu kuqinisa amasosha omzimba, njengasezulwini izilwane ezisencane ngaphezu kutfutfukisa kukhula lokuhlanganisa asebenzayo. Elinye iqembu izilwane - onogwaja hamsters - CLA kuvimbela ukuvaleka kwemithambo yegazi kubangelwa zingcwecwe atherosclerotic. Phambi kwabantu Ekuhloleni okufanayo awazange olwenziwa, ngakho-ke qinisekisa iziphetho ocacile kuyinto kwesikhathi.

Ukuhlolwa ku kwesisindo

Ungathola izitatimende esisiza kakhulu ukunciphisa umzimba conjugated linoleic acid. Izibuyekezo zabantu abaye bazama wesenzo ngakulona, nayo elixutshwe. Abanye abangu akuthandayo abanye umphumela waphawula. Ngo-2000, ososayensi Swedish lanyathelisa imiphumela ucwaningo zabo iqembu lamavolontiya, hudevshih usebenzisa CLA. Bonke izinsuku 64 sokudliwa 3.4g conjugate acid. Hhayi elahlekile omunye umhlanganyeli eyodwa. Ngawo lowo nyaka, ezinye abacwaningi abazimele imiphumela eshicilelwe ziyangqubuzana ucwaningo olwenziwa nomunye iqembu labantu abakhuluphele. Ngokusho la idatha, ukwehla kwesisindo emzimbeni laligujwa nje nalabo ababelandela CLA amalungiselelo. Omunye umsebenzi wokulinga olwenziwa, ososayensi eNorway. Babelana abahlanganyeli ekuhlolweni zibe izigaba ezine, ngasinye engayitholi nsuku zonke CLA kwaba 1.7 g, 3.4 g, 5.1 futhi 6.8. isisindo ukwehla kwaba kuphela wokugcina amaqembu amabili, ngubani idliwe ngemithamo ephakeme zomuthi.

Okuhlangenwe Nakho Nezingxoxo iziphetho Michael Peyriza

Indlela abantu, hhayi nje ezilwaneni conjugated linoleic acid njengendlela kwesisindo? Lezi zifundo yayiqhutshelwa sasivumela enkulu. Ufunde eyenziwa abesilisa nabesifazane babo bonke ubudala okuqondene kwamaqembu ezinhlanga ezihlukahlukene. Michael Peyriz, owathola le ketshezi abathintekayo ekuhlolweni iqembu labantu okhuluphele (amavolontiya 71). kukhona Zonke ngaphakathi 2 izinyanga ngokungaziniki 3.4 amagremu zomuthi nsuku zonke futhi ukulandela ukudla okuyinto akufaki ukudla, sandla isisindo somzimba. Iqembu ukulawula unciphile ngokudla kuphela, ngaphandle imithi. abahlanganyeli Project empeleni Umzimba wami unciphile, kodwa ekupheleni ekudleni futhi waqala ukuthola kuye, baphuza nemithi eyakhelwe kuphela yemisipha, ngesikhathi iqembu ukulawula ukukhula of fat umzimba futhi. Lezi idatha kuzovumela ososayensi ukwenza isitatimende ukuthi CLA esehlisa usayizi fat hhayi kuphela, indlela akunqandi abaningi ngokwengeziwe ukwandisa kubo. Ukuhlolwa wabonisa ukuthi izidakamizwa uyakwazi ukuthuthukisa insulini uketshezi in iziguli sikashukela sohlobo II futhi ukunciphisa izinkomba ambalwa kwegazi glucose. Le miphumela babonakala cishe izingxenye ezimbili kwezintathu owenziwa yizisebenzi zokuzithandela test.

Imithi kanye CLA

Abaningi banesithakazelo umbuzo conjugated linoleic acid lapho izidakamizwa iqukethe. Nazi ezinye esiphakamisiwe Pharmacy kanye nezemidlalo ezitolo Izithako bioactive nale isithako:

1. "Linofit". Okufakiwe yokuhlala amaphilisi angu-60, ngalinye 800 mg acid. Intengo emakethe Russian ruble 1500. Kanye CLA e amaphilisi liqukethe iodine kanye B6, okuyinto kakhulu kwandisa sezindawo ewusizo ibhekwa wezokudla.
2. "Ukukhanya Reduxine." Ikhishwa iphakethe 30, 90, 120 no-180 amaphilisi, ngamunye equkethe 500 mg conjugate acid vitamin E. Inani ruble 1000 kuya 2720 (kuye ngenani amaphilisi).
3. "Chocolate ungukuphila." Packing 10 yakhiwa iphakheji powder CLA kusukela ngalo lesi siphuzo kuyalungiswa. Inani engama-ruble angu-300.

Kukhona futhi nozakwabo bakwamanye amazwe: Zerofat, CLA, CLAextrim nabanye. Intengo kulinganiselwa zamadola 15.

imithombo yemvelo

Kukhona impela eningi lwezakhamzimba ezivela abakhiqizi ezahlukene, lapho ingxenye eyinhloko conjugated linoleic acid. Izibuyekezo Customer ziyahlukahluka kanye imiphumela ucwaningo lwesayensi. Kunabantu abaningi owaphawula nomphumela omuhle. Ngesikhathi esifanayo eziningi zalabo abaye ungazange ulandelwe ukunciphisa isisindo futhi lalilincane kakhulu. Ngaphezu Izithako zokudla, CLA itholakala isigaba enkulu yemikhiqizo yemvelo, ukuze bakwazi udliwe nsukuzonke ngaphandle kwemingcele. Okubonisiwe kumdwebo izibalo ukuze ubisi, inyama namaqanda yizilwane ephakanyiswe ekuphakeleni zemvelo.

Izimo

Hhayi kubonakala ekusebenziseni ezinengqondo imikhiqizo engenhla baxabane emibi emzimbeni (ngaphandle amasosha omzimba ngabanye ngabanye). Ngesikhathi ukusetshenziswa kwezidakamizwa eyayinekheli conjugated linoleic acid, side effects ngeshwa zenzeka. Ngokwesibonelo, abanye amakhasimende abaye esetshenziswa Izithako zokudla nge CLA, waphawula eziya ziba zimbi hemorrhoids nga pre-existing, ukushayisana kwe-wokugaya ukudla pheshana, ukuqubuka, isicanucanu. Ngo abantu Sweden 47 kuphela ngesikhathi sokuhlolwa kusuka 60, owaba nengxenye ukuhlola bakwazi ukudlula yonke inkambo yokuhle. Zonke ezinye baphoqeleka ukuba bangayeki ngenxa ezinye izinkinga zempilo.