Ama-immunomodulators. I-Polyoxidonium (amakhandlela)

Umuthi we-Polyoxidonium (amakhandlela) ubizwa ngokuthi yi-immunomodulator ephumelelayo kakhulu. Ngendlela ye-suppositories, imithi iyona elula kunazo zonke futhi esheshayo.

I-Polyoxidonium (amakhandlela) yezingane isetshenziswa ngesikhathi sezifo ezibangelwa amagciwane ukuze kuthuthukiswe ukuzivikela (ngezinhloso zokuvimbela). Imithi iphinde ibekwe isifo esivele sesivele siphume. Ezimweni ezinjalo, i-Polyoxidonium (amakhandlela) ikhuthaza ukubuyiselwa okusheshayo komzimba, ikhulise ukumelana kwayo nezifo-mgciwane kanye nokulondolozwa kwekhono esikhathini esizayo.

Ngokwezinye izazi, umuthi ungasetshenziswa kanye nanoma yiluphi ukwelashwa. Lokhu, okwenza kube lula ukusebenzisa i-Polyoxidonium (amakhandlela) ekwelapheni izifo zezici ezihlukahlukene.

Ngokwemiyalelo kumuthi, awunayo imiphumela ye-mutagenic, i-carcinogenic, i-teratogenic noma i-allergenic.

Njengoba umkhuba ubonisa, ngokusetshenziswa kwe-Polyoxidonium (ikhandlela), cishe akunamiphumela emibi. Kanye nalokhu, kukhona ukusheshisa okuphawulekayo kokusebenza kokuzivikela. Lokhu kusiza ukwandisa ukumelana komzimba futhi kuqede ukutheleleka esikhathini esifushane kunokujwayelekile.

Ukusebenza kwe-Polyoxidonium (amakhandlela) okulungiselelwa ukubuyekezwa kwezingane kubazali abaningi kunomqondo omuhle kakhulu. Kunakekelwa kakhulu ukuthi kungenzeka ukunciphisa ukusetshenziswa kwemithi ngenkathi yokwelashwa, kanye nekhono lezingxenye zezidakamizwa zokuhlanganisa ubuthi, ukuzisusa emzimbeni. Ngakho, umphumela omubi wemithi unciphise.

Njengoba kunikezwe ukuphepha okuphezulu nokusebenza kahle, umuthi ungasetshenziswa ezinganeni ezineminyaka eyisithupha ubudala. Kodwa-ke, akufanele sikhohlwe ukuthi i-Polyoxidonium iyisidakamizwa esinamandla, ngakho ukuqokwa kwayo kumele kuhambisane nokuphathwa kwezokwelapha. Isidakamizwa sinqunywe ngokucabangela uhlobo lwesifo, isikhathi salo, kanye nezici zenyama. Ngaphambi kokuqokwa komuthi, udokotela kufanele ahlolwe.

Ukulungiselela kuhlanganisa i-polyoxidonium (isithako esisebenzayo), kanye ne-povidone, i-mannitol, i-beta-carotene (amakhophi). Ibhotela le-cocoa isetshenziswa njengesisekelo sokuthola i-suppository.

Indlela yokwenziwa kwe-immunomodulatory ye-Polyoxidonium isekelwe emthethweni oqondile kubabulali bemvelo namaseli we-phagocytic, ukugqugquzela ukubunjwa kwama-antibody. Isidakamizwa sinomphumela wokubuyisela okuhloswe ngazo izimpendulo ze-immune ezimweni ze-secondary immunodeficiency states, ezingabangelwa ukutheleleka, ukushisa, ukuhlukumezeka, ama-neoplasms amabi. Imithi isetshenziswa kakhulu ukuvimbela izinkinga ngemuva kokungenelela kokuhlinzwa, ukusetshenziswa kwe-chemotherapy.

Isidakamizwa sinomthelela omubi we-detoxification effect, sandisa ukumelana kwamagqabhezana amangqamuzana nemiphumela ye-cytotoxic yezidakamizwa namakhemikhali, ukunciphisa ubuthi babo. Lezi zakhiwo zingenxa yemvelo ephakeme yesisindo semvelo kanye nesakhiwo se-Polyoxidonium.

Ukulungiswa ngendlela ye-suppository kune-bioavailability ephezulu (kufika ku-70%). Ukugxila okuphezulu kwegazi kutholakala emva kwehora.

Ngenxa yokuntuleka kokwelashwa kokusetshenziswa kwabesifazane ngesikhathi sokubeletha, akukhuthazwa ukusebenzisa amakhandlela abesifazane abakhulelwe. Ithuluzi lokuphikisana futhi uma kukhona ukuzwela okukhulu emiphumeleni yezingxenye. Ngokunakekelwa okukhethekile, imithi inqunyelwe abantu abanezinkinga zokungasebenzi.

Isingeniso se-suppository kubantu abadala senziwa ngokuqondile noma ngokweqile. Ukuphathwa kwe-Rectal kwenziwa kanye ngosuku ngosuku lokudlulisa emva kokuhamba kwamathumba. Umjovo wangasese uqhutshwa endaweni ephezulu emzimbeni ubusuku kanye ngosuku. Ezinganeni ezineminyaka engaphezu kwengu-6, umthamo uwu-0.20-0.25 mg / kg isisindo somzimba. Izingane zithola ama-suppository ngokuqondile.