Umuthi 'Nicergoline ": ukubuyekezwa, yokusetshenziswa

ukuthi umuthi ngempumelelo "Nicergoline"? Ukubuyekeza, analogs netimphawu leli thuluzi kuzoxoxwa ngakho esihlokweni. Futhi, uzofunda ukuthi umthamo ezinqunyiwe iziguli.

Incazelo, ukubunjwa, ifomu zomuthi

Ngayiphi ifomu umkhiqizo izidakamizwa "Nicergoline"? Leli bhukwana uthi leli thuluzi itholakala amafomu amabili:

• Lyophilizate e ingilazi ampoules (isb powder emhlophe ngaphandle iphunga), zahlanganiswa ngendlela nentaba cell PVC kanye amakhadibhodi amabhokisi, ngokulandelana, kanye kuphela (ama-0.9% sodium chloride) esetshenziselwa ukulungiswa isixazululo umjovo.

Yiziphi izithako leli thuluzi? Iqukethe nicergoline nobisi ushukela tartaric acid.

• Biconvex amaphilisi nge ifilimu-camera ezimhlophe, zahlanganiswa ngo amabhamuza.

Yini izingxenye uhlanganisa kubhekwe uhlobo "Nicergoline" izidakamizwa? Ngaphezu kwalokho homonymous isithako e izibhebhe zihlanganisa ejenti ezilandelayo: amazambane isitashi, magnesium eziyisisekelo carbonate, i-lactose, povidone, stearic acid kanye magnesium stearate.

Ngokuphathelene igobolondo elimhlophe, liphethe eziyisisekelo magnesium carbonate, sucrose, colloidal Silicon dioxide, ngengcina yezinyosi, povidone, ama-titanium dioxide, talc kanye gelatin wezokwelapha.

izici Pharmacodynamic kusho: izici

izindlela Kubhekwe vasodilating isenzo (ngamanye amazwi, inomthelela Umthambo palsy), futhi libhekisela eqenjini i-alpha-blocker.

Ukulungiselela "Nicergoline-LF" izilinganiso okuyinto ethulwa ngezansi, kuyinto esuselwe zokwenziwa of-alpha-adrenergic okuzivelelayo bese ergot alkaloids. Ngo ifomula amakhemikhali kusho ukuthi iqukethe izinsalela bromo nicotinic acid.

I asebenzayo ingxenye izidakamizwa, futhi ergoline esuselwe ukukhuthaza nemiphumela elihle hemodynamic futhi izinqubo umzimba ezenzeka ubuchopho bomuntu.

Ngenxa yokuthi lo muthi kubhekwe has-alpha 1-adrenoceptor Ukuvinjwa isinyathelo, kwandisa izinga ukugeleza engayitholi emaphashini, ubuchopho, futhi emikhawulweni, futhi kunciphisa aggregation zegazi egazini futhi kuthuthukisa imingcele hemorheologic. Futhi, lolu kwakwakhe izidakamizwa liveza izindawo spasmolytic futhi ngesikhathi esifanayo inikeza umphumela myotropic ku ezicutshini semithambo kwandisa permeability glucose futhi equalizes iringi umphumela ergolinovogo.

I izakhiwo eziyinhloko zomuthi

Kuyini ephawulekayo yindlela ngokuthi "Nicergoline"? ochwepheshe lezivakashi baphikisa ngokuthi izidakamizwa kunciphisa ithoni nemikhumbi, lwemithambo ukugeleza kwegazi igcwalisa nomoya-mpilo kanye glucose. libuye libe nethonya elizuzisa ku blood pressure, okungase kancane kancane abuyele nomfutho wegazi ophezulu evamile.

Kumele kuqashelwe futhi ukuthi imithi kubhekwe ngcono imingcele hemorheological, kanye ukwehla platelet wokuhlanganisa nokusakazwa anda arteriopathy.

I pharmacokinetics zomuthi

I nomuthi "Nicergoline" izilinganiso okuyizinto lomuhle kakhulu, ifinyelela lokuhlushwa wobuningi egazini imizuzu 90 ngemuva kokuqala. I bioavailability ye-ejenti imayelana 60%.

Kusukela umzimba wesiguli-80% nomuthi kuyinto okukhipha ngokusebenzisa izinso (umchamo), no-20% - kanye indle.

Izinkomba ukusetshenziswa

Uma iziguli ezinqunyiwe isidakamizwa "Nicergoline"? Ukubuyekezwa (amaphilisi kanye imijovo elinegama elifanayo edayiswa zonke drugstores) kufanele ubeke ukuthi izinkomba esiyinhloko ukusetshenziswa kwalesi imithi yilezi ezilandelayo uthi:

• migraine;
• ukuphazamiseka umzimba ngokwemvelo semithambo cerebral esingamahlalakhona noma oyingozi, kubangelwa isifo sokuqina kwemithambo yegazi, umfutho ophakeme wegazi, ukuhlaselwa ischemic, embolism, vasospasms, thrombotic noma umsangano obangwa yi semithambo;
• isifo Raynaud sika;
• inzululwane;
• angiopathy sikashukela ;
• iziyaluyalu kwegazi (neuropathy);
• retinopathy sikashukela;
• isifo occlusive;
• peripheral we emsipheni optic;
• esitho arteriopathy;
• izifo corneal.

Izimo

Yiziphi ngezimo zesiguli liyakwenqabela ukusetshenziswa imithi "Nicergoline"? Ukubuyekezwa (imijovo kanye amaphilisi babe munye Izimo efanayo) usho enqabelo ezilandelayo:

• hypersensitivity;
• ukungabekezelelani galactose;
• esivimba amanzi;
• hypotension;
• ukhulelwe;
• bradycardia;
• yobudala ezincane;
• ibele;
• zikashukela-galactose malabsorption;
• yokuntuleka kwe-lactose.

Okumele kuqashelwe Lo muthi kufanele esetshenziswa abantu nge sifo, hyperuricemia, kanye lihambisana ejenti ezithinta umzimba futhi kukhuthaza ka uric acid emzimbeni.

Nomuthi "Nicergoline": yokusetshenziswa

Uphenyo odokotela bathi kusho okumele zithathwe imithamo Kunconywa ngokuqinile. Njengomthetho, "Nicergoline" ithebhulethi iqondiswa kathathu ngosuku ngaphambi kokudla ukudla noma lapho abadla umthamo 5-10 mg.

Ubude yokwelashwa nale imithi ngokuvamile 3 amaviki. Kodwa uma kunesidingo, le nkathi singase siwathole izinyanga eziningana.

Ngaphambi ukusetshenziswa, lyophilisate "Nicergoline" kufanele buhlanjululwe kuphela (nge-sodium chloride) kulandele intramuscularly (kabili ngosuku 4.2 mg). Ubude sokwelashwa umthamo ithuluzi zincike kobukhulu kanye nohlobo lesi sifo, futhi ngezimo zesiguli.

Abantu nge sezinso kahle umsebenzi kubhekwe izidakamizwa Kunconywa ukusebenzisa aphansi amanani kunokwenzeka.

Imiphumela emibi ngemuva kokusebenzisa imithi

imiphumela emibi ebekiwe imiyalelo izidakamizwa "Nicergoline". Izibuyekezo Umthengi wazise ukuthi phakathi isicelo sale ukulungiselela ngokuvamile zihlangabezane ezifana ukusabela ezingezinhle njengoba:

• isicanucanu, wehlise blood pressure, ukozela;
• Ubuhlungu obukhulu besisu, ukusabela iguliswa, isiyezi;
• imfiva, uhudo, anda amazinga acid uric nokuqwasha.

Overdose, izidakamizwa ukuxhumana

Ziyini izimpawu okubangwa ukusetshenziswa amazinga okukhishwa enkulu izimali? Izimpawu, okuwuphawu ukweqisa izidakamizwa kukhona uthi ezifana hypotension Orthostatic, hypotension nokungezwani komzimba. Ngaphezu kwalokho, lapho esingeqile udokotela watusa imithamo zomuthi ezigulini iyakhula kakhulu kobukhulu engemihle.

Ngokusho imiyalelo, le nomuthi "Nicergoline" uyakwazi potentiating kusebenta izidakamizwa antipsychotic futhi antihypertensive, kanye anxiolytics. Qaphela ukuthi antacids futhi colestyramine ukunciphisa ukumuncwa kwe-nomuthi.

Izidakamizwa asetshenziswa parallel adrenostimulyatorov iziguli zingase isici esiyingqayizivele.

Izidakamizwa "Nicergoline": Izibuyekezo iziguli nodokotela, analogs

Analogue ithuluzi yizidakamizwa ezifana "Nilogrin", "Sermion" futhi "Nicergoline-Fereyg".

Okubukwe imithi akuvumelekile sisetshenziswa ndawonye izidakamizwa kwezidakamizwa notshwala.

Ukuze ugweme hypotension, kuhlanganise ekuqaleni ukwelashwa, ngemuva ujove esicutshini yesixazululo izidakamizwa iziguli zidinga ukuhlala endaweni evundlile isikhathi esithile.

Kufanele kuphawulwe ukuthi iningi odokotela phakathi imithi yokwelapha "Nicergoline" enqabela iziguli zabo ukushayela izimoto, kanye abenza ngawo imisebenzi enjalo, edinga osheshayo lengqondo ukusabela okuhlushwa ukugqanyiswa.

Njengoba abathengi, bayizithunywa ngobuningi zigcine we "Nicergoline" ukulungiselela Izibuyekezo ezingezinhle. Lena ngokuyinhloko ngenxa yokuthi ukuthi iziguli kaningi kakhulu ebhekene yayo eceleni-nemiphumela, kanye isikhathi eside akazange uqaphela ngcono, futhi izidakamizwa umphumela.