"Trypsin": yokusetshenziswa. "Trypsin": Izibuyekezo

Kule minyaka eminyakeni embalwa omkhulu ethandwa enzyme proteolytic ngoba enzyme, njengemoto esebenzisa "Chymotrypsin" futhi "Trypsin". Yokusetshenziswa ibika ukuthi le mithi kuyabekwa pathologies amehlo. Ngokokuqala ngqá, la ma-enzyme ezikhonjwe ezinto American noprofesa Dzhon Hauard ezilwaneni zokuhlola. Basuke ekhiqizwa amanyikwe izinkomo nokuhlaba izilwane ezincelisayo. Kuvulwa ngaphansi kwethonya trypsin futhi enterokinase.

Ngokusebenzisa ososayensi ucwaningo okuphindaphindiwe baye baphetha ngokuthi ama-enzyme proteolytic kungenziwa wayisebenzisa zamehlo (njengoba elwa namagciwane, eqeda ukuvuvukala kanye decongestant), ukwelapha cataract, uveitis, iziyaluyalu ukucindezeleka kwangemva kwenhlekelele ubudala, maphakathi ngwengwzi vein thrombosis amehlo subluxation lens, iridocyclitis futhi ubovu icubungula lacrimal iziteshi.

Kufanele kuqashelwe ukuthi overdosing at indlela ehlukile usebenzisa alibonakali. Kodwa nakuba isikhona ububanzi sasivumela ububanzi kwezicelo, udaba idatha imithi izidakamizwa limiswe ngenkathi wokugoqa wase-USSR. Ukukhiqizwa inkampani esanda kumiswa e-Ukraine Kiev, oveza ejenti webhaktheriya ngaphansi kwegama lomkhiqizo "Biopharma".

Indlela etholakalayo?

Amalungiselelo "Trypsin" futhi "chymotrypsin" kuze kube manje kukhiqizwa endaweni lyophilized ezimhlophe crystalline powder abangenalo iphunga akukho. Kuyinto encibilikayo kalula nosawoti namanzi abavamile. Emitholampilo zamehlo yokwelapha subconjunctival, esicutshini futhi umjovo emthanjeni.

Asetshenziswa ngesimo inhalations, namabhati pripudrivany. Electrophoresis kabanzi ukwelapha izifo eziningi. Le ndlela yokuphathwa inikeza imiphumela ngempumelelo ngesikhathi imithamo ongaphakeme Ngokungafani nezinye izindlela kwesicelo. Ubufakazi besayensi bubonisa ukuthi umsebenzi enzyme ngisho ngaphansi ukuchayeka esikhona manje esingekho encishisiwe.

Le nqubo ivumela ngempumelelo aphathe ukopha ku zamehlo, futhi esiwohlozayo-dystrophic, ingcina nezinqubo ukuvuvukala. Ukulungiselela "Trypsin", yokusetshenziswa okuyinto itusa ngezinhloso zokwelapha e nokopha ngwengwzi nazo elisetshenziswa chorioretinitis, ukonakala macular, atrophic izinqubo endophthalmitis futhi izinzwa optic.

Yini umsebenzi zomzimba womuntu ithwala trypsin?

Enzyme abathintekayo kulo cleavage ka peptides futhi amaprotheni hydrolyzing ku izakhi lula. Ukhicita izidakamizwa crystalline uhlelo lwethu ngendlela amanyikwe trypsinogen (enzyme asisebenzi). Ngemva ke engena duodenum, trypsin ivuswe ngu the enteropeptidase enzyme kanye Bile. Mayelana iziyaluyalu sokugembula we wendlala kubonisa ukungabi endleni yabantu abanaleli ketshezi. Trypsin e sezinyawo kungabuye Kutholwe cystic lapho pancreatic.

Uphakamisa uphinde wehlise umsebenzi enzyme igazi ukhuluma ngani?

Akuvamile Kutholwe in iziguli komdlavuza futhi izifo ezibangelwa amagciwane. Umsebenzi e serum ngokuvamile kwehliswa kubantu abaphethwe umdlavuza, pancreatitis okungamahlalakhona, cystic fibrosis kanye nesifo sikashukela. Ukuze zokugula esolwa ukulungiselela ebekiwe idatha "Trypsin" (crystalline).

Imithi Pharmaceutical Imikhiqizo

Ingabe i-ejenti eqeda ukuvuvukala, kusiza mncane isikhwehlela viscous. Nobanda izimila fibrinous nezicubu efile. It is wafakazela ukuthi izidakamizwa ayinayo wethonya elonakalisayo ku hemostasis.

Ngayiphi izifo uqokwa esebenzisa 'trypsin "?

Yokusetshenziswa abonisa ngokucacile ukuthi imithi kuqeda izifo umgudu wokuphefumula: ukucinana kwemigudu yokuphefumula, inyumoniya, tracheitis, empyema, atelectasis nasezinkingeni ezilandela ngemva kokuhlinzwa pleurisy exudative. Ngaphezu kwalokho, imithi enqunywe udokotela ekwelapheni isifo periodontal, osteomyelitis, thrombophlebitis, iridocyclitis, sinusitis kanye nabezindaba otitis. Izidakamizwa kusiza ukulimala, bedsores, ukusha kanye amanxeba iqhubeka.

nokushintsha kokudla nokufakwa

Isixazululo of trypsin crystalline isetshenziswa ngezindlela eziningana.

Ngesimo electrophoresis, aerosol, ngemithambo yegazi futhi intraplevralno. Isikhathi yokwelapha ngokuvamile kusukela imijovo 6 kuya ku-15. Ngaphambi ukusebenzisa (abadala) 0.005 g nto ziyoncibilika oyinyumba sodium chloride isixazululo (0.9%) noma procaine.

Lapho emanxebeni nasezilondeni zokusha ukwenza licindezele ihlelwe ngokulandelana kwezihloko (njengoba by izimpushana noma isixazululo trypsin). Ngaphambi kokufaka isicelo ibhandishi 50 mg lomcebo u buhlanjululwe in 5 ml i-sodium chloride noma amanzi oyinyumba. Isilonda aphathwa, futhi zizosetshenziswa cindezela izinsuku ezimbili. Ngezikhathi oswakanyiswe ngebhandeshi isinqandakuvunda gauze eyomile ngeke kube umphumela oyifunayo. Uma emva kwezinsuku 24 Isilonda awumanga, inqubo iyaphindwa.

Ngesimo amathonsi: okwenza imithi 0.2-0.25% isixazululo.

Ngu ephefumula: isidakamizwa iqondiswa usebenzisa bronchoscope, noma nesifutho wezokwelapha. Ngemva uhlambulule ngomlomo ingaphakathi ukwelashwa, futhi amavesi acinene ngamanzi oyinyumba.

side effects

Ezimweni ezingavamile, nokungezwani komzimba nezinto zingenzeka. Inhalation ekuphathweni kungabonakala nasemkhakheni indlela hoarseness yephimbo, ububomvu kanye ukucasuka we zokuphefumula ipheshana mucosa. Lapho iqondiswa ngemithambo yegazi, iziguli wembula hyperemia kusayithi umjovo, ububomvu kancane nesisa.

Izimo

Okunqatshelwe iqondiswa ukopha nokulungiselela surface "Trypsin". Imiyalelo isicelo ixwayisa ukuthi akunakwenzeka ukusebenzisa ukulibopha endaweni yokukhuluma izimila ebulalayo. Kusho sokuwohloka contraindicated futhi ngokoma kwesibindi, pancreatitis, oluhambisana diathesis kanye ne-hepatitis ezithathelwanayo. Futhi, ungayisebenzisi somoya bronchial, emphysema namafomu acute isifo sofuba. Abantu ne hypersensitivity kufanele kuphenduke ngenye imithi.

izimo isitoreji

It bathengisa kuphela kadokotela. Ngaphambi kokuba uthenge qinisekisa ukubheka okungapheli (hhayi eminye iminyaka emithathu). Gcina imithi esiqandisini kungcono - emnyango, noma endaweni epholile, omile futhi avikelwe elangeni ezingeni lokushisa hhayi ephakeme kuka-10 ° Inqubomgomo Intengo ^C. kuhluka ruble angu-400 izitsha eziyisikhombisa eziyishumi.

Izidakamizwa yesenzo efanayo

Lezi zihlanganisa izidakamizwa "Pax-trypsin", "Terridekaza", "Ribonuclease", "Asperaza", "Lizoamidaza", "Daltseks" futhi "Profezim". izidakamizwa "Trypsin" kutholakala kuphela amaphilisi. Wamafutha ngesisekelo yalolu ketshezi ngokuthi "Irukson".

isiphetho

Zokwelapha, ama-enzyme proteolytic "trypsin" futhi "Chymotrypsin" esungulwe ngokwabo njengoba amathuluzi amahle kakhulu ekulweni pathologies eziningi. Basuke ngokuvamile sisetshenziswa ejensi amehlo ekwelapheni nokopha encane, ukuvuvukala kanye Schwarte, kusukela izinqubo kungabangela pathologies okukhulu (embonweni ukulahlekelwa) ngenxa yokuphathwa kabi okungafanele.

Kuze kube manje, ukusetshenziswa enzyme lihambisana elwa namagciwane yesimanje, antihistamine, ukufiphala kwamehlo futhi i-hormone amalungiselelo izikhathi eziningana ngcono ukusebenza kahle ekwelapheni izifo iso. Incazelo kanye nemiyalelo ethulwa zokwaziswa, ngokuzimela akunikeze imithi kuyingozi empilweni. Siphakamisa ukuthi uxhumane udokotela i ukusazi ngokunembile isifo esikuphethe lesi sifo. Futhi, uyothola ukuthi une yokungezwani komzimba emuthini.

Ukubukwa iziguli

Abantu abaningi zama ukubona ngamehlo engqondo lokhu imithi, ngokuvamile zikhuluma ngendlela ekhuthazayo ke. Abanye-ke kwenza ukuba alulame ngokushesha futhi uthole balulame. Excellent kusiza ukuba sibhekane ngokuphumelelayo nezifo emalungeni: aqede ubuhlungu, kunciphisa ukuvuvukala futhi ubuyisela motor umsebenzi. Iziguli eziningi kakhulu ukwelashwa usebenzisa izidakamizwa "Trypsin".

Izibuyekezo ngendlela enhle ngalokhu izidakamizwa ngokuvamile mningi. Ithuluzi esisemqoka ukusikeka eqinile futhi ukulimala. Ngemuva kokufaka isicelo cindezela kunciphisa ukuvuvukala, ububomvu kanye kusheshe izicubu ukuvuselelwa. Akekho iziguli uzwakalise ukunganeliseki.

odokotela siqu kanye nochwepheshe badumise luhlobo futhi bakubheka njengesipho okudingeka bashintshashintshe ngayo futhi esebenza kahle kakhulu. Nayo ungakwazi ukufeza emangalisayo yi zokwelapha. Iningi leziguli ezine-izifo umgudu wokuphefumula ziye zasiza ke imuncwe "Trypsin" isixazululo. Ukuze izinsukwana kuyinto ubalekela lingaze, umuntu azizwa kuqubule amandla.

Iziguli kokuthatha lesi imithi kuthiwa wanelisa, kanye abasebenzi bezempilo abazikhandla linqume ukuba aphathe. enzyme Proteolytic ukubonisa imiphumela ngempumelelo ezindaweni eziningi. Nakekela impilo yakho futhi sidlule inkambo yokwelapha ngendlela esifike ngesikhathi.