Kusukela lokho kusiza, "famotidine"? Yokusetshenziswa, ngempela

Bewazi yini ukuthi kulokho kusiza "famotidine"? Phendula lo mbuzo can kuphela udokotela. Uma isikhathi babonisana nodokotela ungenalo ke sizobe ukukhuluma ngalokhu izidakamizwa kule athikili.

Uzofunda ukuthi izakhiwo akushilo nomuthi, njengoba injena, ngasiphi izifo isetshenziswa, lokho likhona ngezithako zawo, njalo njalo.

Ukubunjwa izidakamizwa emabhokisini futhi incazelo ifomu

Ngayiphi ifomu ukukhululwa nomuthi "famotidine"? Manual ithi leli thuluzi zingatholakala ngesimo amaphilisi. Sinenkosi simise we-lenticular wangakwesokunxele isiyingi, kanye ifilimu camera okhanyayo nsundu noma ube phuzi.

Yiziphi izithako kuhlanganisa izidakamizwa "famotidine"? Ukwakheka izidakamizwa ilula: isakhi esiyinhloko - famotidine. Ngaphandle impahla isizinda, ithuluzi ehlanganisa ukwesekwa, ezifana neze-cellulose microcrystalline, corn isitashi, magnesium stearate, talc, Silicon dioxide kanye sodium croscarmellose.

Ngokuphathelene amaphilisi, sifaka macrogol 6000, hypromellose, talc, ama-titanium dioxide nensimbi oxide udayi ensundu.

Umuthi ukudayiswa ukucabangela iza ibhamuza amaphakethe, okuyinto tihlelwe ephepheni emaphaketheni.

Kufanele kugcizelelwe ukuthi ukulungiswa "ka famotidine" okuyinto lenkulumo kukhonjisiwe ngezansi, ikhiqizwa ngemithamo ehlukene - 40 no-20 mg.

Izici zomuthi

Ngaphambi kokuba siphendule lo mbuzo eyenza "famotidine" kufanele usitshele ukuthi izidakamizwa isebenza. Ngokusho imiyalelo, umenzeli ndaba okuvimba ka-receptor H2-histamine. Ibonisa anti-isilonda izakhiwo.

Ingqikithi oyinhloko zomuthi kunomthelela nokucindezela basal acid umkhiqizo (hydrochloric acid) esiswini. Ngaphezu kwalokho, famotidine kunciphisa ukukhuthazwa histamine, acetylcholine futhi gastrin futhi juice esiswini kwandisa pH, pepsin umsebenzi futhi kunciphisa ukukhiqizwa HCL.

Ngenxa alolu okwandisiwe glycoprotein kumiswa kusho ukwanda isikhwehlela esiswini kanye ukukhuthazwa prostaglandin zamagama. Through the uketshezi hydrogen lokuzuziwe nekutsi yimpandla isilonda ukuphulukisa izakhiwo zomuthi.

imithi Okubukwe kusiza ukopha esiswini, ephulukisa umonakalo ku lwamafinyila yayo kanye nezibazi izilonda ukucindezeleka.

I izakhiwo zomuthi

Ukulungiselela "Famotidine" (intengo analogs izidakamizwa ezibalwe ngezansi) has awakuthinti ohlelweni inkulumo (oxidase) enzyme cytochrome P450 esibindini.

Effect Its lokhu izidakamizwa iqala emva kwemizuzu 65, kuthatha cishe usuku.

I kinetics kwezidakamizwa

I nomuthi "Famotidine", ogama ukufundwa ethulwa ngezansi, ngemva kokuphathwa temlomo amuncwa umzimba kusukela amathumbu. okuhlushwa (esiphezulu) Igazi lawo izuzwe kungakapheli amahora amathathu.

Ukuxhumana zemithi plasma amaprotheni kuyinto 15-20%. It is excreted ku obisini lukamama futhi lingena ngokusebenzisa isithiyo esinomhlapho.

Cishe 30-35% of the esebenzayo izidakamizwa izidakamizwa ngaphansi ukucatshangelwa is akheka esibindini. Loku S-oxide.

Ukuqedwa ithuluzi senzeka ngokuyinhloko inqamula nezinso. Cishe 27-40% of the izidakamizwa excreted ku umchamo ngefomu zinjalo. isigamu-ukuphila "ka famotidine" isikhathi 3-4 amahora. Abantu ne-CC engaphansi kuka-30 ml ngomzuzu le Inkomba luyanda amahora 11-12.

Kusukela lokho kusiza "famotidine"?

Kwezinye izimo, ukubika imithi udokotela? Ngokusho imiyalelo, ukuthola izinkomba kulo muthi okulandelayo uthi:

• uhlelo mastocytosis;
• zokuvimbela ngiwela ogibeni lwezidakamizwa, wokugaya ukudla ipheshana isilonda isifo;
• Reflux esophagitis;
• gastro erosive;
• nokuvinjelwa ngiwela ogibeni lwezidakamizwa, okuyizinto ezihlobene nokusetshenziswa eside ama-NSAID;
• Zollinger-Ellison syndrome;
• dyspepsia ukusebenza, okuyinto lihlotshaniswa umsebenzi wawanda (secretory) isisu;
• izilonda emathunjini, ukucindezeleka futhi lingaze;
• Ukuvimbela nenshisekelo of juice esiswini ezigulini othola ukuhlinzwa ngaphansi izinzwa jikelele (isb Mendelson Syndrome);
• amaningi endocrine adenomatosis;
• zokuvimbela ukuphinda ezophayo, kuhlanganise kwaba ngemva kwezikhathi zokulotshwa-op;
• Ukuvimbela nenshisekelo pneumonitis;
• neuralgia ne ubuhlungu ubuhlungu retrosternal noma epigastric ezenzeka ebusuku noma ehambisana nokudla ukudla okuthile.

Uvala izidakamizwa ukusetshenziswa

Manje uyazi, kulokho kusiza "famotidine". Kodwa ngaphambi kokuba ukhethe lokhu imithi, kufanele uzijwayeze imiyalelo. Lo muthi contraindicated ukuthola ku:

• lactation;
• e ezingaphansi kweminyaka emithathu ubudala (esisindo engaphansi kwengama-20 kg);
• sokukhulelwa;
• hypersensitivity kuya famotidine, nezinye blocker futhi receptor H2-histamine.

Nge ukuqapha okukhethekile wathi imithi engabelwe esingamahlalakhona hepatic noma kwezinso, kwamasosha omzimba, isibindi sibe sesomile futhi encephalopathy portosystemic ezinganeni.

Indlela "famotidine"?

Lo muthi ebekiwe ngaphakathi. Musa ukuhlafuna amaphilisi, wageza phansi imali eyanele ketshezi.

Abadala kubhekwe izidakamizwa Kufanele umise udokotela (kuye ngokuthi ubufakazi) kuphela.

Ngezinye isilonda ka ipheshana wokugaya ukudla, ikakhulu esigabeni oyingozi kanye nezilonda futhi lingaze gastroduodenite erosive nomuthi asebenzayo ukuncoma ukuthatha 20 mg kabili ngosuku, noma kanye isamba 40 mg (ubusuku). Uma wayefisa, umthamo wansuku zonke zomuthi kungase kushintshwe futhi ngakhula ukuze 80-160 mg.

Ubude yokwelashwa nale ejenti singemaviki lange 6-8.

Ngokuba nokuvimbela isilonda uyahluleka uma elwa nokuphuza izidakamizwa "Famotidine" Izimo lapho yabalwa, 20 mg iqondiswa kanye ngosuku, ngesikhathi sokulala.

Lapho dyspepsia, okuyinto lihlotshaniswa uketshezi anda esiswini, imithi Kunconywa ukuthatha ngesikhathi umthamo ofanayo.

Uma kukhona refpyuks imithi oesophagitis walisebenzisa kabili ngosuku 20-40 mg amasonto 6-12.

Ukuvimbela nenshisekelo of juice esiswini ngaphansi jikelele izinzwa nomuthi iqondiswa e isamba 40 mg kusihlwa noma ngokushesha ngaphambi nje kokuba ahlinzwe.

Lapho Zollinger-Ellison syndrome umthamo kanye isikhathi sokusebenza kwawo asethwe ngamunye. Ngokuvamile, umthamo kokuqala umuthi 20 mg. Thatha le Ikhambi kufanele kube njalo emahoreni ayisithupha. Uma kudingeka, inani nomuthi kungase kukhule ku 160 mg ngesikhathi esifanayo reception imvamisa.

Ephambi kwezinduna ukwehluleka kwezinso (isib CC engaphansi kuka-30 ml ngeminithi) nsuku zonke nokushintsha kokudla nokufakwa izindlela kumele ibe ngu- mg 20.

Sokuphuzisa ezinganeni

Kusukela lokho kusiza "famotidine" izingane? Lokhu kusho izingane babelwe ngezizathu ezifanayo njengoba abadala. GI isilonda i isigaba exacerbation, futhi Reflux esophagitis Kunconywa ukuthatha imithi ngokuvumelana uhlelo ezilandelayo: 2 mg ngayinye 1 kg esisindo ngosuku. Lokhu ngobungako izidakamizwa sehlukaniswe izinyathelo ezimbili.

side effects

izindlela Kubhekwe kungadala ezifana side effects njengoba:

• nomlomo owomile, arrhythmia, isicanucanu, induna vulgaris, ukuhlanza;
• Alopecia, ubuhlungu besisu, isikhumba esomile, ukuvuvukala, kunciphisa umfutho wegazi, ukuqunjelwa;
• ukuqubuka kwesikhumba, ukukhishwa isisu, AV-block, isifiso neziyaluyalu, angioedema;
• kwesibindi, ukulunywa, ama-enzyme isibindi ephakeme, ukushaqeka anaphylactic;
• pancreatitis acute, izimpawu hypersensitivity, ikhanda;
• bronchospasm, isiyezi, komzimba, ukuqwasha, yokuhlala paresis;
• bradycardia, ukukhathazeka, ukudideka, tinnitus, vasculitis;
• leukopenia, ukukhathala, anda amazinga egazi urea, ukuhhema, agranulocytosis, ukozela;
• thrombocytopenia, ukucindezeleka hypoplasia, uvalo pancytopenia, sengqondo;
• umnkantsha aplasia, angaboni kahle, hyperprolactinemia;
• imfiva, ukulahlekelwa libido, ukuqaqamba kwamalunga omzimba, gynecomastia, ubuthakathaka, amenorrhea, ukhwehlela nobuhlungu bomzimba.

Izindleko kanye analogue

Izindleko kwalo mkhiqizo ngokuthi "famotidine" kuyinto ruble mayelana 30-55. Uma kudingeka, kungase kuthathelwe indawo analogue ezifana "Gastromaks", "Kvamatel", "Gastrotid", "ulfamid", "Famozol", "Famodingeksal", "Famosan".

imithi Izibuyekezo

Izidakamizwa "famotidine" - a ethandwa kakhulu anti-isilonda ejenti. Iziguli zithi ngempumelelo kuzibonakalisa yizifo ezihlobene nokungabikho pheshana emathunjini. Isikhathi esining impela ke ezinqunyiwe kolwelwesi kanye nezilonda.

Enye inzuzo yokuhamba kwesikebhe lokhu umuthi cheapness yayo isihlobo.

Ngokuqondene Izibuyekezo ezingezinhle ngalesosikhathi they are izikhalazo evame kakhulu mayelana imiphumela emibi yemithi.