Isidakamizwa "i-Xylometazoline": imiyalo yokusetshenziswa, incazelo, ukubunjwa, ukufana nokubuyekezwa

Yini oyaziyo ngomuthi we-Xylometazoline? Imiyalo yokusetshenziswa, ukwakheka kwalesi sidakamizwa kuzochazwa ngezansi. Kusukela esihlokweni esifanayo uzothola ukuthi le mithi ibaluleke kangakanani, kungakhathaliseki ukuthi inqunyelwe izingane, ukuthi zenziwe ngamuphi uhlobo, yiziphi izinkampani zokungafani nemiphumela emibi okufanele zaziwe.

Ifomu, incazelo, ukwakheka, ukupakisha

Ungathenga indawo ekhonjiwe kulezi zinhlobo ezilandelayo:

• 0.05% noma 0.1% amaconsi emanzini "Xylometazoline". Imiyalo yokusetshenziswa ithi ingxenye esebenzayo yalesi sidakamizwa i-xylometazoline hydrochloride. Njengoba izakhi ezisizayo hydrophosphate, i-sodium chloride, i-potassium dihydrogen phosphate ne- benzalkonium chloride isetshenziswa. Ukudayiswa, isisombululo esicacile, esingenombabala noma esiphuzi sitholakala emabhodleleni e-polymer one-dispenser.
• 0,05% no-0,1% i-aerosol "i-Xylometazoline" (i-spray). Imfundo yemibiko yokusetshenziswa ukuthi ingxenye enkulu yalesi sidakamizwa i-xylometazoline hydrochloride. Ngaphezu kwalokho, iqukethe izithako ezingasebenziyo ngendlela ye-disodium edetate dihydrate, i-sodium hydrophosphate, i-eucalyptus amafutha, i-potassium dihydrogen phosphate, i-benzalkonium chloride, i-chloride ye-sodium, i- sorbitol, i-macrogol glyceryl hydroxy stearate ne-glycerin. Isidakamizwa sigcwele amaphodlela e-polymer ane-nebulizer, ehlanganiswe emaphaketheni ekhadibhodi.
• Gel "i-Xylometazoline". Imfundo yokusetshenziswa igomela ukuthi leli fomu lomuthi liqukethe nesici esisebenzayo ngendlela ye-xylometazoline hydrochloride. Ngaphezu kwalokho, imithi ihlanganisa izingxenye ezilandelayo ezisizayo: i-glycerol, i-carbomer, i-propylene glycol, ikhambi le-ammonia, i- propylparaben, i-ethanol, amanzi ne-methyl paraben.

Izakhiwo zomzimba

Iyini i-Xylometazoline? Imiyalo yokusetshenziswa (inani lemithi elibalwe ngezansi) lithi liyi-decongestant, i-antiticongestive ne-vasoconstrictor. Isisetshenziswa saso esiyinkimbinkimbi yisisetshenziswa se-imidazoline.

Isidakamizwa sikwazi ukugqugquzela i-α1- ne-α2-adrenoreceptors yemikhumbi ye-mucosa yama-nasopharyngeal. Njengomphumela wale mphumela, ukuvuvukala nama-hyperemia we-mucosa wehla, futhi inani lokuphuma ekhaleni liyehla.

Ngemuva kokusebenzisa ikhambi lendawo, ukuphefumula kwesiguli kuba lula kakhulu. Le mithi ijwayele ukusetshenziselwa izimo ezigulayo, i-rhinitis nezifo ezihlukahlukene ze-sinanas paranasal.

I-Xylometazoline isebenzisa kanjani? Umyalelo wokusetshenziswa uzisa ukuthi leli fomu lokulungiselela lihlanganisa namafutha eucalyptus. Lokhu kunikeza izakhiwo ezilwa nokuvuvukala nokulwa nomzimba. Ukusetshenziswa kwe-aerosol kusiza ukunciphisa ukuvuvukala kwe-mucosa yangasese.

Njengomthetho, isenzo sesidakamizwa esibucayi sibonakala emahoreni angu-¼ futhi sihlala amahora angaba ngu-10.

Pharmacokinetics yomuthi

Yimiphi imingcele ye-pharmacokinetic eyenza umuthi "i-Xylometazoline"? Imfundo yokusetshenziswa ithi lezi zakhiwo azikafundiwe. Ngokusetshenziswa komuthi wendawo, ukumamatheka kwayo kwanele ukuthuthukisa imiphumela yesistimu.

Izinkomba

Yini engasetshenziselwa le mithi? Ngokomyalelo, leli thuluzi limiselwe:

• Nge-rhinopharyngitis;
• I-Rhinitis ye-etiologies ehlukahlukene (i-virus, i-allergic, ibhaktheriya, ibuhlungu);
• I-Otitis media kanye ne-eustachyte.

Futhi, "i-Xylometazoline" isetshenziselwa ukuhlukaniswa okulula kwemfihlo ngesinusiti nezinqubo zokuxilonga emagatsheni angasese.

Ukungafani

Ingabe ukulungiswa kwendawo "i-Xylometazoline" kunezinqatshaniswa? Imiyalo yokusetshenziswa (izingane kanye nabantu abadala, lesi sidakamizwa sisetshenziswa ngokulinganayo njalo) kubika okuvinjelwe okulandelayo:

• Kudala kuze kube seminyaka emibili;
• Angina pectoris;
• ITachycardia;
• Isifo se-hypertensive;
• I-Glaucoma;
• Hyperplasia of the prostate;
• I-atherosclerosis ekhulu;
• Isifo sikashukela sikhona;
• I-Thyrotoxicosis;
• I-Atrophic pharyngitis ne-rhinitis engavamile;
• Ukuziphendulela komuthi kumuthi.

Ngokunakekelwa okukhethekile lo muthi unqunywe ngesikhathi sokukhulelwa. Ekusebenzeni kwezingane, imithi ayisetshenziselwa ukuhlushwa kwe-0.1% (kuze kube seminyaka emibili).

Ikhambi lasendaweni "i-Xylometazoline": imfundo emuthi

Ukusetshenziswa kwale mithi kufanele kusetshenziswe kuphela nge-intranasally.

Amaphesenti angu-0.1% emakhaleni anqunyelwe iziguli ezikhulile 2 amaconsi epasini ngayinye emanzini emvamisa kathathu ngosuku.

I-0.1% spray isetshenziselwa abantu abadala ngokucindezela okulodwa (okungukuthi, 0.1 mg) kumbhalo ngamunye. Ukwenza lokhu, umfakisicelo ufakwa emakhaleni, kodwa ngesikhathi esifanayo isikhundla sokugcina sesitsha sigcinwa. Isidakamizwa sijojowe kathathu ngosuku amahora ayisishiyagalombili.

0.1% i-gel inqunyelwe abantu abadala ukuya kwamaconsi amathathu kathathu ngosuku.

Ngenxa yokwakheka kwe-systemic kanye nemiphumela emibi, zonke izilinganiso eziphakanyiswa udokotela kufanele zigcinwe ngokucophelela.

Ukusebenzisa noma yiluphi uhlobo lweminye imithi akufanele kube ngaphezu kwezinsuku ezinhlanu. Ungasebenzisi lesi sidakamizwa isikhathi eside nge-rhinitis engavamile.

Uma kwenzeka ukuthi kunezinsika ezisezintanjeni, kungcono ukusebenzisa i-gel 0.1%.

Ngomthamo ongabanjwanga, i-dose elandelayo akufanele iphindwe kabili.

Izenzakalo ezimbi

Isidakamizwa "i-Xylometazoline" (amaconsi) asenza ukusabela okubi? Imiyalelo yokusetshenziswa iqinisekisa ukuthi noma yiluphi uhlobo lomuthi olubuzwayo lungabangela imiphumela elandelayo engathandeki:

• Sneezing;
• Ukuvutha emphinjeni nasemakhaleni;
• Ukuqwashisa;
• Ukucasula kwe-mucosa;
• Ukwanda kwegazi;
• Ukushisa kwe-nasopharyngeal mucosa;
• Ukuvota;
• Izinwele;
• Umbono ongenakwenzeka;
• Isizungu;
• ITachycardia;
• Ukukhulisa okukhulu;
• I-Heart rhythm disorder;
• I-Edema ye-mucosa yomzimba;
• Ukucindezeleka.

Ukudlula ngokweqile kwalesi sidakamizwa

Uma usebenzisa imithi yokwelapha eyengeziwe, lezi zibonakaliso ezilandelayo zingase zivele esigulini: i-cyanosis, abafundi abahlanjululwe, ukuhlanza, i-arrhythmia, i-nausea, i-edema ye-pulmonary, umkhuhlane, ukuhluleka ukuphefumula, i-tachycardia, ukucindezeleka okukhulu, ukuboshwa komzimba nokukhathazeka kwengqondo.

Izimpawu ezifana nokulala, i-coma, i-bradycardia ne-apnea, ziphakamisa ukususwa kwe-CNS.

Njengoba ukwelashwa kwezimo ezinjalo, ukugcoba esiswini, ukuphefumula okufakelwayo, ukungenisa izidakamizwa kanye nezidakamizwa zokunciphisa ukucindezelwa kwegazi, kanye nama-anticonvulsant kanye nama-antipyretic agents.

Ukusebenzisana kwezidakamizwa

Izidakamizwa ezithokozisa uhlelo oluzwelayo zingathuthukisa umphumela we-Xylometazoline.

Le mithi ayikwazi ukuhlanganiswa nama-antidepressants nama- MAO inhibitors, ngoba ukusebenzisana kwabo kunomthelela ekwenzeni isimo se-hypertensive.

Ama-analogue namanani

Ukulungiswa kwendawo "Xylometazoline" kubiza malini? Thenga le thuluzi ngokuchofoza ongakwenza ngama-ruble angu-68-75, futhi ngesimo se-gel ne-spray - yama-ruble angu-53-63.

Ngokuqondene nezifanekiselo, okuvamile kakhulu imithi elandelayo: Merialis, Pharmazoline, Tizin Xylo, Pharmazoline N, Otryvin nge menthol kanye ne-eucalyptus, iGalazolin, Otryvin, i-Xylo-mefa ".

Ukubuyekeza mayelana nomuthi

Ukubuyekezwa kwe-"Xylometazoline" yendawo kungcono kakhulu. Iziguli ziphawula ukuthi ukusebenza kahle kwale mithi.

Ngokusho kwezibuyekezo, izidakamizwa ezinjengamahlumela okwenyuka kunzima kunalokho, ngoba ingxenye yesisombululo ingena ngokungenakuphika ku-pharynx, okubangela ukuba kube nemiphumela emibi. Ngakho-ke, iziguli eziningi zikhetha ukusebenzisa i-sprayed spray.

Abantu abaningi baqaphela ukusabela okungathandeki okulandelayo emva kokusebenzisa lesi sidakamizwa: i-neurosis, ukuleleka nokuvusa ukukhathazeka.

Kanti futhi, ezinye iziguli zikhuluma nge-ricochet stagnation, okuthiwa i-rhinitis yezokwelapha. Ukusetshenziswa isikhathi eside kwezidakamizwa kunomthelela ekunciphiseni izitsha, okushintshwa ukuqhutshwa kokukhipha nokukhuphuka kwegazi. Ukunyanyiswa kwamasongo kubuya futhi.

Ngokusetshenziswa isikhathi eside kwesidakamizwa, i-atrophy ye-mucosa yangasese iqala. Ukuze ugweme izimo ezinjalo, kufanele unciphise ukusetshenziswa kwezidakamizwa ezinsukwini ezintathu.