'Iressa' (gefitinib) intengo analogue. Njengoba ukuthenga a "Iressa"

Ukulungiselela "Iressa" kuyinto inhibitor ka tyrosine kinase (isb ikhemikhali suppresses ukukhiqizwa lokhu enzyme kanye physico-chemical izinqubo ezihlobene nazo). Tyrosine kinase kuvusa epidermal ngokukhula sici for sebuningini izimila ezinkulu. A Isenzo izidakamizwa kubambezela inqubo futhi, ngaphezu kwalokho, kuvimbela ukuvela nokwanda Ukudlulela isimila kumiswa imikhumbi igazi ngesivinini inqubo apoptosis (ubole amaseli ebulalayo zibe ahlukene izingxenye hlangothi).

The main isithako "Iressa" izidakamizwa - gefitinib - hhayi kuphela sivimbela ukukhula izimila, kodwa futhi kwandisa ukuphumelela kwezindlela radiotherapy, amakhemikhali okwelapha kanye therapy hormone.

Mayelana imithi ejwayelekile izidakamizwa

Thanda isethi anti-isimila izidakamizwa isizukulwane esisha, amaphilisi "Iressa" intengo impela high (kuba emhlabeni izinkulungwane 300. Deda.). Ngokuvamile lokhu kwenza ukuba nesimo esinzima ekubulaleni iziguli ezigulela ukuthenga kubo. Ukumhlenga kulesi simo kuziwa ejwayelekile "Iressa» - Geftinat, oluqanjwe inkampani owaziwa Indian Natco Pharma.

Uqambe izidakamizwa ezivezwa ilayisensi esemthethweni futhi akuhlukile sabafowabo uphawu. Anakho ukwakheka efanayo futhi, ngokufanelekile, nekusebenta efanayo njengoba 'Iressa', intengo yayo ingaphansi kakhulu kulesi simo.

Okunjalo kungenxa yokuthi ukubaluleka ejwayelekile akuyona wabeka ibhizinisi izindleko asathuthuka, ukuhlolwa kanye nokukhangisa. Lokhu kunciphisa kakhulu izindleko futhi, ngenxa yalokho, intengo okudayisa izidakamizwa.

Kuphi ukuthenga izidakamizwa "Iressa" futhi analogue yayo

ERussia, generic "Iressa" yizimboni abadumile Indian ayatholakala kwiwebhusayithi okhethekile nge ezinkulu Indian inkampani 5 ngonyaka idumela WWW.ONKO24.COM. Ngaphezu kwalokho, ukuthenga ejwayelekile, uzochitha imali kakhulu kancane njengoba intengo izikhathi ezingaphezu kweziyisishiyagalombili nokuba eziyishumi ngaphansana izidakamizwa uphawu.

Imigomo Yesevisi - ukutholakala imibhalo efanele, okungase uqinisekise isidingo ukwelashwa yesimanje.

izinkomba

"Iressa" inikezwa kuphela udokotela ukuba khona, uma kudingeka deceleration isimila esibulalayo esikhula ukukhula emaphashini futhi bronchi, kanye sitholakele metastatic umdlavuza wamaphaphu.

Ngempumelelo "Iressa" izidakamizwa izidakamizwa ngempumelelo uma amaseli angavamile kusukela abanomdlavuza akuzona ekuthonyweni imiphumela emibi yokwelashwa ngamakhemikhali platinum amalungiselelo.

Indlela ukuthatha lesi sidakamizwa "Iressa": isitatimende

Ithuluzi yakhelwe kuphela ukusetshenziswa ngomlomo. Uphuzwe ngokuqinile njengoba uyalelwe ngudokotela wakho - kwelinye futhi ngesikhathi esifanayo, ngaphandle ngokuqhathanisa ngayo ukudla.

Njengomthetho, "Iressa" kanye ejwayelekile yayo sabelwe iphilisi elilodwa kanye ngelanga. Ezimweni lapho, nganoma isiphi isizathu, kanye imithi iye uphuthelwe, kufanele kwenziwe amahora kungakadluli 12 ngaphambi hulumeni omusha.

Phawula amaphilisi amabili ngesikhathi umthamo engamukeleki!

Uma isiguli singenakukwazi ukugwinya ithebhulethi iyonke, kungashiwo ziyoncibilika 100 ml amanzi carbonated, ngaphandle esisuka, aphuze noma faka nesineke ngepayipi. Futhi ukuze uthole kuleli cala, umthamo umnyuziki ngokuphuza okuqukethwe ingilazi egcwele amanzi futhi ngokugeza izindonga, baphuze.

In iziguli nge komzimba, inyumoniya interstitial, uhudo olubi nezinye imiphumela engemihle wazithatha ngesikhatsi ukwelashwa, kungenzeka ikhefu isicelo zomuthi ezinsukwini ezingu-14. Ngemva kwalokho ukwelashwa kufanele kuqhutshwe ngaphansi kohlelo ejwayelekile.

side effects

Kuyatholakala ku-izidakamizwa "Iressa" Izibuyekezo bathi ezivamile side effects e inqubo reception kukhona isikhumba kanye induna, ukulunywa, isikhumba esomile kanye nolwelwesi lwamafinyila, stomatitis, kanye nesifo sohudo.

Lezi ukusabela ngokuvamile ngenyanga yokuqala yokwelapha futhi emuva. 3% kuphela iziguli ukusabela ezingezinhle ophoqelelwe ukwelashwa ukumisa okuthuthukile.

Ngaphezu kwalezi, zibonakala neminye imiphumela engathandeki:

• umongozima;
• isicanucanu;
• ukuhlanza;
• asthenia;
• sokuzincisha;
• conjunctivitis;
• blepharitis;
• ukushintsha ipuleti nail;
• komzimba;
• xerophthalmia;
• inyumoniya interstitial (indiva izimpawu zaso ebulalayo kungenzeka).

Ukusetshenziswa kwezidakamizwa kuholela izinguquko kwamanye imingcele laboratory. Ngokwesibonelo, egazini isiguli luyanda creatinine futhi bilirubin, futhi umchamo - amaprotheni.

Izimo izidakamizwa

"Iressa" akuyona inikezwa iziguli, ngubani iguliswa izidakamizwa kufakwe tablet. Futhi hhayi esetshenziswa paediatrics futhi ekwelapheni kwabesifazane abakhulelwe noma asebekhulile.

Ephambi kwezinduna idiopathic cystic yamaphaphu, pneumoconiosis, ama-enzyme isibindi kuphakame bilirubin, kanye lezinceku lactose ukungabekezelelani izidakamizwa kumele kusetshenziswe ngokuqapha.

Iziguli samakhaza concomitant (ukulungiselela, post-emisebeni noma interstitial), ukusetshenziswa amaphilisi 'Iressa' kufanele kwenziwe ngaphansi kokuqondisa esiqinile of onguchwepheshe.

ukweqisa izidakamizwa

Isikali okweqile kungaholela ekuphazamisekeni kwemikhuba ezinzima imisebenzi emathunjini, ukuqubuka kwesikhumba futhi izimpawu okusezingeni eliphezulu kobukhulu engemihle.

Ukuze ekwelapheni ukweqisa izidakamizwa ukwelashwa lingaze isicelo.